Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50152191 (Phosphoric acid 5-(4-amino-2-oxo-2H-pyrimidin-1-yl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Georgia Curated by ChEMBL | Assay Description Inhibitory activity against 3'-processing step in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrate | Bioorg Med Chem Lett 14: 4815-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.050 BindingDB Entry DOI: 10.7270/Q2QV3N8B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50152191 (Phosphoric acid 5-(4-amino-2-oxo-2H-pyrimidin-1-yl...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Georgia Curated by ChEMBL | Assay Description Inhibitory activity against strand transfer in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrate | Bioorg Med Chem Lett 14: 4815-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.050 BindingDB Entry DOI: 10.7270/Q2QV3N8B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50152192 (Phosphoric acid 4-(6-amino-purin-9-yl)-3-hydroxy-t...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Georgia Curated by ChEMBL | Assay Description Inhibitory activity against strand transfer in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrate | Bioorg Med Chem Lett 14: 4815-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.050 BindingDB Entry DOI: 10.7270/Q2QV3N8B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50152189 (Phosphoric acid 5-(6-amino-purin-9-yl)-2-phosphono...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Georgia Curated by ChEMBL | Assay Description Inhibitory activity against strand transfer in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrate | Bioorg Med Chem Lett 14: 4815-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.050 BindingDB Entry DOI: 10.7270/Q2QV3N8B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50152190 (Phosphoric acid 5-(6-amino-purin-9-yl)-2-phosphono...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.14E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Georgia Curated by ChEMBL | Assay Description Inhibitory activity against strand transfer in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrate | Bioorg Med Chem Lett 14: 4815-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.050 BindingDB Entry DOI: 10.7270/Q2QV3N8B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50152192 (Phosphoric acid 4-(6-amino-purin-9-yl)-3-hydroxy-t...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Georgia Curated by ChEMBL | Assay Description Inhibitory activity against 3'-processing step in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrate | Bioorg Med Chem Lett 14: 4815-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.050 BindingDB Entry DOI: 10.7270/Q2QV3N8B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50152189 (Phosphoric acid 5-(6-amino-purin-9-yl)-2-phosphono...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Georgia Curated by ChEMBL | Assay Description Inhibitory activity against 3'-processing step in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrate | Bioorg Med Chem Lett 14: 4815-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.050 BindingDB Entry DOI: 10.7270/Q2QV3N8B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50152190 (Phosphoric acid 5-(6-amino-purin-9-yl)-2-phosphono...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Georgia Curated by ChEMBL | Assay Description Inhibitory activity against 3'-processing step in wild-type HIV-1 integrase was determined using 21-mer oligonucleotide substrate | Bioorg Med Chem Lett 14: 4815-7 (2004) Article DOI: 10.1016/j.bmcl.2004.07.050 BindingDB Entry DOI: 10.7270/Q2QV3N8B | |||||||||||
More data for this Ligand-Target Pair |