Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM50156570 (1-[3-aminomethyl-3-deoxy-2-O-,6-N-(thiocarbonyl)-b...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM50156573 (1-(3-aminomethyl-2-O-,6-N-carbonyl-3-deoxy-beta-D-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM50118625 ((R)-1-((R)-3-Chloro-4-hydroxy-5-methylphosphate-te...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM1 (dT | thymidine) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM50156571 (1-[3-(azidomethyl)-2,3-dideoxy-alpha-D-erythro-pen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM50156568 (1,3-bis[(3R)-(3'-deoxythymidin-3'-yl)methyl]urea |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM50156572 (1-[3-C-(azido-methyl)-2,3-dideoxy-beta-D-thereo-pe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM50118623 ((R)-1-((R)-3-Fluoro-4-hydroxy-5-methylphosphate-te...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM50131909 (1-((2R,4R,5S)-4-aminomethyl-5-hydroxymethyl-tetrah...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM50156576 (1-(3-azidomethyl-2,5-difluoro-2,3,5-trideoxy-beta-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM50156574 (1-(3-azidomethyl-2,3-dideoxy-2-fluoro-beta-D-ribof...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.65E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM50156575 (1-(3-azidomethyl-2-chloro-2,3-dideoxy-beta-D-ribof...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Homo sapiens (Human)) | BDBM1 (dT | thymidine) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of human TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Homo sapiens (Human)) | BDBM50131909 (1-((2R,4R,5S)-4-aminomethyl-5-hydroxymethyl-tetrah...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of human TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Mycobacterium tuberculosis) | BDBM50156569 (1-[3-aminomethyl-2-chloro-2,3-dideoxy-beta-D-ribof...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Homo sapiens (Human)) | BDBM50156570 (1-[3-aminomethyl-3-deoxy-2-O-,6-N-(thiocarbonyl)-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of human TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Homo sapiens (Human)) | BDBM50156572 (1-[3-C-(azido-methyl)-2,3-dideoxy-beta-D-thereo-pe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.04E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of human TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate kinase (Homo sapiens (Human)) | BDBM50156573 (1-(3-aminomethyl-2-O-,6-N-carbonyl-3-deoxy-beta-D-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ghent University Curated by ChEMBL | Assay Description Inhibition of human TMPK by coupled spectrophotometric assay | J Med Chem 47: 6187-94 (2004) Article DOI: 10.1021/jm040847w BindingDB Entry DOI: 10.7270/Q24M95B1 | |||||||||||
More data for this Ligand-Target Pair |