Found 47 hits Enz. Inhib. hit(s) with all data for entry = 50038048 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM35847
((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | PDB
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PDB
Article
PubMed
| 0.790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM35847
((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | PDB
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PDB
Article
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| 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224577
(4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-oxopy...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C22H25BrN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29) | PDB
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| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224575
((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...)Show SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C22H25BrN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29)/t20-/m1/s1 | PDB
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| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224572
(4-(2-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C22H25ClN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29) | PDB
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| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224570
((S)-4-(2-(2-(3-hydroxy-4-(3-iodophenyl)butyl)-5-ox...)Show SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(I)c1 Show InChI InChI=1S/C22H25IN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29)/t20-/m1/s1 | PDB
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| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224574
(4-(2-(2-(3-hydroxy-4-(3-iodophenyl)butyl)-5-oxopyr...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(I)c1 Show InChI InChI=1S/C22H25IN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29) | PDB
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| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224586
(4-(2-(2-(4-(3-fluorophenyl)-3-hydroxybutyl)-5-oxop...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(F)c1 Show InChI InChI=1S/C22H25FN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29) | PDB
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| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224583
(4-(2-(2-(3-methyl-4-(3-phenethylphenyl)butyl)-5-ox...)Show SMILES CC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(CCc2ccccc2)c1 Show InChI InChI=1S/C31H36N2O3/c1-24(22-28-9-5-8-27(23-28)11-10-25-6-3-2-4-7-25)16-19-32-20-18-30(34)33(32)21-17-26-12-14-29(15-13-26)31(35)36/h2-9,12-15,23-24H,10-11,16-22H2,1H3,(H,35,36) | PDB
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| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224584
(4-(2-(2-(3-hydroxy-4-(3-(trifluoromethyl)phenyl)bu...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C23H25F3N2O4/c24-23(25,26)19-3-1-2-17(14-19)15-20(29)9-11-27-12-10-21(30)28(27)13-8-16-4-6-18(7-5-16)22(31)32/h1-7,14,20,29H,8-13,15H2,(H,31,32) | PDB
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| 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224581
(4-(2-(2-(3-hydroxy-4-(3-(trifluoromethoxy)phenyl)b...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H25F3N2O5/c24-23(25,26)33-20-3-1-2-17(15-20)14-19(29)9-11-27-12-10-21(30)28(27)13-8-16-4-6-18(7-5-16)22(31)32/h1-7,15,19,29H,8-14H2,(H,31,32) | PDB
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| 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224580
(4-(2-(2-(3-hydroxy-4-phenylbutyl)-5-oxopyrazolidin...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C22H26N2O4/c25-20(16-18-4-2-1-3-5-18)11-13-23-14-12-21(26)24(23)15-10-17-6-8-19(9-7-17)22(27)28/h1-9,20,25H,10-16H2,(H,27,28) | PDB
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| 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224578
((S)-4-(2-(2-(3-hydroxy-4-phenylbutyl)-5-oxopyrazol...)Show SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C22H26N2O4/c25-20(16-18-4-2-1-3-5-18)11-13-23-14-12-21(26)24(23)15-10-17-6-8-19(9-7-17)22(27)28/h1-9,20,25H,10-16H2,(H,27,28)/t20-/m1/s1 | PDB
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| 134 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224571
(4-(2-(2-(3-hydroxyoctyl)-5-oxopyrazolidin-1-yl)eth...)Show InChI InChI=1S/C20H30N2O4/c1-2-3-4-5-18(23)11-13-21-14-12-19(24)22(21)15-10-16-6-8-17(9-7-16)20(25)26/h6-9,18,23H,2-5,10-15H2,1H3,(H,25,26) | PDB
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| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224582
(4-(2-(2-(4-(3-(2-cyclopropylethyl)phenyl)-3-hydrox...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(CCC2CC2)c1 Show InChI InChI=1S/C27H34N2O4/c30-25(19-23-3-1-2-22(18-23)7-6-20-4-5-20)13-15-28-16-14-26(31)29(28)17-12-21-8-10-24(11-9-21)27(32)33/h1-3,8-11,18,20,25,30H,4-7,12-17,19H2,(H,32,33) | PDB
Reactome pathway
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| 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224583
(4-(2-(2-(3-methyl-4-(3-phenethylphenyl)butyl)-5-ox...)Show SMILES CC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(CCc2ccccc2)c1 Show InChI InChI=1S/C31H36N2O3/c1-24(22-28-9-5-8-27(23-28)11-10-25-6-3-2-4-7-25)16-19-32-20-18-30(34)33(32)21-17-26-12-14-29(15-13-26)31(35)36/h2-9,12-15,23-24H,10-11,16-22H2,1H3,(H,35,36) | PDB
Reactome pathway
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| 560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224579
(4-(2-(2-(4-hydroxy-4-(1-propylcyclobutyl)butyl)-5-...)Show SMILES CCCC1(CCC1)C(O)CCCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H34N2O4/c1-2-12-23(13-4-14-23)20(26)5-3-15-24-16-11-21(27)25(24)17-10-18-6-8-19(9-7-18)22(28)29/h6-9,20,26H,2-5,10-17H2,1H3,(H,28,29) | PDB
Reactome pathway
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| 750 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224576
(4-(2-(2-(4-hydroxynonyl)-5-oxopyrazolidin-1-yl)eth...)Show InChI InChI=1S/C21H32N2O4/c1-2-3-4-6-19(24)7-5-14-22-15-13-20(25)23(22)16-12-17-8-10-18(11-9-17)21(26)27/h8-11,19,24H,2-7,12-16H2,1H3,(H,26,27) | PDB
Reactome pathway
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| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224568
(4-(2-(2-(3-hydroxy-5-methylhexyl)-5-oxopyrazolidin...)Show InChI InChI=1S/C19H28N2O4/c1-14(2)13-17(22)8-10-20-11-9-18(23)21(20)12-7-15-3-5-16(6-4-15)19(24)25/h3-6,14,17,22H,7-13H2,1-2H3,(H,24,25) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224570
((S)-4-(2-(2-(3-hydroxy-4-(3-iodophenyl)butyl)-5-ox...)Show SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(I)c1 Show InChI InChI=1S/C22H25IN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29)/t20-/m1/s1 | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Similars
| Article
PubMed
| 2.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224571
(4-(2-(2-(3-hydroxyoctyl)-5-oxopyrazolidin-1-yl)eth...)Show InChI InChI=1S/C20H30N2O4/c1-2-3-4-5-18(23)11-13-21-14-12-19(24)22(21)15-10-16-6-8-17(9-7-16)20(25)26/h6-9,18,23H,2-5,10-15H2,1H3,(H,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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PC sid
UniChem
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PubMed
| 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224574
(4-(2-(2-(3-hydroxy-4-(3-iodophenyl)butyl)-5-oxopyr...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(I)c1 Show InChI InChI=1S/C22H25IN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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Similars
| Article
PubMed
| 2.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224576
(4-(2-(2-(4-hydroxynonyl)-5-oxopyrazolidin-1-yl)eth...)Show InChI InChI=1S/C21H32N2O4/c1-2-3-4-6-19(24)7-5-14-22-15-13-20(25)23(22)16-12-17-8-10-18(11-9-17)21(26)27/h8-11,19,24H,2-7,12-16H2,1H3,(H,26,27) | PDB
Reactome pathway
KEGG
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UniChem
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| Article
PubMed
| 2.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224569
(4-(2-(2-(3-hydroxy-4-methylheptyl)-5-oxopyrazolidi...)Show InChI InChI=1S/C20H30N2O4/c1-3-4-15(2)18(23)10-12-21-13-11-19(24)22(21)14-9-16-5-7-17(8-6-16)20(25)26/h5-8,15,18,23H,3-4,9-14H2,1-2H3,(H,25,26) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Patents
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PubMed
| 2.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224581
(4-(2-(2-(3-hydroxy-4-(3-(trifluoromethoxy)phenyl)b...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C23H25F3N2O5/c24-23(25,26)33-20-3-1-2-17(15-20)14-19(29)9-11-27-12-10-21(30)28(27)13-8-16-4-6-18(7-5-16)22(31)32/h1-7,15,19,29H,8-14H2,(H,31,32) | PDB
Reactome pathway
KEGG
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UniChem
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Similars
| Article
PubMed
| 2.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224575
((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...)Show SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C22H25BrN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29)/t20-/m1/s1 | PDB
Reactome pathway
KEGG
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UniChem
Similars
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PubMed
| 3.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224568
(4-(2-(2-(3-hydroxy-5-methylhexyl)-5-oxopyrazolidin...)Show InChI InChI=1S/C19H28N2O4/c1-14(2)13-17(22)8-10-20-11-9-18(23)21(20)12-7-15-3-5-16(6-4-15)19(24)25/h3-6,14,17,22H,7-13H2,1-2H3,(H,24,25) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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| Article
PubMed
| 4.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224577
(4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-oxopy...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C22H25BrN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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Similars
| Article
PubMed
| 5.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224572
(4-(2-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C22H25ClN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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PC sid
UniChem
Patents
Similars
| Article
PubMed
| 5.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224584
(4-(2-(2-(3-hydroxy-4-(3-(trifluoromethyl)phenyl)bu...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C23H25F3N2O4/c24-23(25,26)19-3-1-2-17(14-19)15-20(29)9-11-27-12-10-21(30)28(27)13-8-16-4-6-18(7-5-16)22(31)32/h1-7,14,20,29H,8-13,15H2,(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224569
(4-(2-(2-(3-hydroxy-4-methylheptyl)-5-oxopyrazolidi...)Show InChI InChI=1S/C20H30N2O4/c1-3-4-15(2)18(23)10-12-21-13-11-19(24)22(21)14-9-16-5-7-17(8-6-16)20(25)26/h5-8,15,18,23H,3-4,9-14H2,1-2H3,(H,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
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| CHEMBL
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PC sid
UniChem
Patents
Similars
| Article
PubMed
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224580
(4-(2-(2-(3-hydroxy-4-phenylbutyl)-5-oxopyrazolidin...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C22H26N2O4/c25-20(16-18-4-2-1-3-5-18)11-13-23-14-12-21(26)24(23)15-10-17-6-8-19(9-7-17)22(27)28/h1-9,20,25H,10-16H2,(H,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224586
(4-(2-(2-(4-(3-fluorophenyl)-3-hydroxybutyl)-5-oxop...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(F)c1 Show InChI InChI=1S/C22H25FN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 6.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224582
(4-(2-(2-(4-(3-(2-cyclopropylethyl)phenyl)-3-hydrox...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(CCC2CC2)c1 Show InChI InChI=1S/C27H34N2O4/c30-25(19-23-3-1-2-22(18-23)7-6-20-4-5-20)13-15-28-16-14-26(31)29(28)17-12-21-8-10-24(11-9-21)27(32)33/h1-3,8-11,18,20,25,30H,4-7,12-17,19H2,(H,32,33) | PDB
Reactome pathway
KEGG
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GoogleScholar
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224578
((S)-4-(2-(2-(3-hydroxy-4-phenylbutyl)-5-oxopyrazol...)Show SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1ccccc1 Show InChI InChI=1S/C22H26N2O4/c25-20(16-18-4-2-1-3-5-18)11-13-23-14-12-21(26)24(23)15-10-17-6-8-19(9-7-17)22(27)28/h1-9,20,25H,10-16H2,(H,27,28)/t20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224579
(4-(2-(2-(4-hydroxy-4-(1-propylcyclobutyl)butyl)-5-...)Show SMILES CCCC1(CCC1)C(O)CCCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H34N2O4/c1-2-12-23(13-4-14-23)20(26)5-3-15-24-16-11-21(27)25(24)17-10-18-6-8-19(9-7-18)22(28)29/h6-9,20,26H,2-5,10-17H2,1H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Binding affinity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224572
(4-(2-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Cl)c1 Show InChI InChI=1S/C22H25ClN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224571
(4-(2-(2-(3-hydroxyoctyl)-5-oxopyrazolidin-1-yl)eth...)Show InChI InChI=1S/C20H30N2O4/c1-2-3-4-5-18(23)11-13-21-14-12-19(24)22(21)15-10-16-6-8-17(9-7-16)20(25)26/h6-9,18,23H,2-5,10-15H2,1H3,(H,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 595 | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224568
(4-(2-(2-(3-hydroxy-5-methylhexyl)-5-oxopyrazolidin...)Show InChI InChI=1S/C19H28N2O4/c1-14(2)13-17(22)8-10-20-11-9-18(23)21(20)12-7-15-3-5-16(6-4-15)19(24)25/h3-6,14,17,22H,7-13H2,1-2H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224579
(4-(2-(2-(4-hydroxy-4-(1-propylcyclobutyl)butyl)-5-...)Show SMILES CCCC1(CCC1)C(O)CCCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H34N2O4/c1-2-12-23(13-4-14-23)20(26)5-3-15-24-16-11-21(27)25(24)17-10-18-6-8-19(9-7-18)22(28)29/h6-9,20,26H,2-5,10-17H2,1H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 393 | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224571
(4-(2-(2-(3-hydroxyoctyl)-5-oxopyrazolidin-1-yl)eth...)Show InChI InChI=1S/C20H30N2O4/c1-2-3-4-5-18(23)11-13-21-14-12-19(24)22(21)15-10-16-6-8-17(9-7-16)20(25)26/h6-9,18,23H,2-5,10-15H2,1H3,(H,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224577
(4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-oxopy...)Show SMILES OC(CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C22H25BrN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224569
(4-(2-(2-(3-hydroxy-4-methylheptyl)-5-oxopyrazolidi...)Show InChI InChI=1S/C20H30N2O4/c1-3-4-15(2)18(23)10-12-21-13-11-19(24)22(21)14-9-16-5-7-17(8-6-16)20(25)26/h5-8,15,18,23H,3-4,9-14H2,1-2H3,(H,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224576
(4-(2-(2-(4-hydroxynonyl)-5-oxopyrazolidin-1-yl)eth...)Show InChI InChI=1S/C21H32N2O4/c1-2-3-4-6-19(24)7-5-14-22-15-13-20(25)23(22)16-12-17-8-10-18(11-9-17)21(26)27/h8-11,19,24H,2-7,12-16H2,1H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50224575
((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...)Show SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C22H25BrN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29)/t20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human prostaglandin EP2 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224568
(4-(2-(2-(3-hydroxy-5-methylhexyl)-5-oxopyrazolidin...)Show InChI InChI=1S/C19H28N2O4/c1-14(2)13-17(22)8-10-20-11-9-18(23)21(20)12-7-15-3-5-16(6-4-15)19(24)25/h3-6,14,17,22H,7-13H2,1-2H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 277 | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50224575
((S)-4-(2-(2-(4-(3-bromophenyl)-3-hydroxybutyl)-5-o...)Show SMILES O[C@H](CCN1CCC(=O)N1CCc1ccc(cc1)C(O)=O)Cc1cccc(Br)c1 Show InChI InChI=1S/C22H25BrN2O4/c23-19-3-1-2-17(14-19)15-20(26)9-11-24-12-10-21(27)25(24)13-8-16-4-6-18(7-5-16)22(28)29/h1-7,14,20,26H,8-13,15H2,(H,28,29)/t20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human prostaglandin EP4 receptor |
Bioorg Med Chem Lett 17: 6572-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.074
BindingDB Entry DOI: 10.7270/Q29887V9 |
More data for this
Ligand-Target Pair | |
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