Found 44 hits Enz. Inhib. hit(s) with all data for entry = 50039106 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50366567
(ATOMOXETINE)Show InChI InChI=1S/C17H21NO/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3/t17-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE PC cid PC sid UniChem
Similars
| DrugBank Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313549
(CHEMBL1085197 | CHEMBL1204411 | {3-[1-(2-Fluoro-ph...)Show InChI InChI=1S/C18H21FN2O2S/c1-20-12-6-8-15-13-14-7-2-4-10-17(14)21(24(15,22)23)18-11-5-3-9-16(18)19/h2-5,7,9-11,15,20H,6,8,12-13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313550
(CHEMBL1085198 | CHEMBL1204412 | {3-[1-(2,6-Difluor...)Show InChI InChI=1S/C18H20F2N2O2S/c1-21-11-5-7-14-12-13-6-2-3-10-17(13)22(25(14,23)24)18-15(19)8-4-9-16(18)20/h2-4,6,8-10,14,21H,5,7,11-12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313552
(CHEMBL1096001 | CHEMBL1204414 | {3-[6-Fluoro-1-(2-...)Show InChI InChI=1S/C18H20F2N2O2S/c1-21-10-4-5-15-12-13-11-14(19)8-9-17(13)22(25(15,23)24)18-7-3-2-6-16(18)20/h2-3,6-9,11,15,21H,4-5,10,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313548
(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)Show InChI InChI=1S/C18H22N2O2S/c1-19-13-7-11-17-14-15-8-5-6-12-18(15)20(23(17,21)22)16-9-3-2-4-10-16/h2-6,8-10,12,17,19H,7,11,13-14H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313553
(CHEMBL1099373 | CHEMBL1204415 | {3-[1-(2,6-Difluor...)Show InChI InChI=1S/C18H19F3N2O2S/c1-22-9-3-4-14-11-12-10-13(19)7-8-17(12)23(26(14,24)25)18-15(20)5-2-6-16(18)21/h2,5-8,10,14,22H,3-4,9,11H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313551
(CHEMBL1095367 | CHEMBL1204413 | [3-(6-Fluoro-2,2-d...)Show InChI InChI=1S/C18H21FN2O2S/c1-20-11-5-8-17-13-14-12-15(19)9-10-18(14)21(24(17,22)23)16-6-3-2-4-7-16/h2-4,6-7,9-10,12,17,20H,5,8,11,13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313553
(CHEMBL1099373 | CHEMBL1204415 | {3-[1-(2,6-Difluor...)Show InChI InChI=1S/C18H19F3N2O2S/c1-22-9-3-4-14-11-12-10-13(19)7-8-17(12)23(26(14,24)25)18-15(20)5-2-6-16(18)21/h2,5-8,10,14,22H,3-4,9,11H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313543
(CHEMBL1087924 | {3-[1-(2-Fluoro-phenyl)-2,2-dioxo-...)Show InChI InChI=1S/C17H20FN3O2S/c1-19-11-6-12-20-13-14-7-2-4-9-16(14)21(24(20,22)23)17-10-5-3-8-15(17)18/h2-5,7-10,19H,6,11-13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313547
(CHEMBL1083211 | {4-[6-Fluoro-1-(2-fluoro-phenyl)-2...)Show InChI InChI=1S/C18H21F2N3O2S/c1-21-10-4-5-11-22-13-14-12-15(19)8-9-17(14)23(26(22,24)25)18-7-3-2-6-16(18)20/h2-3,6-9,12,21H,4-5,10-11,13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313544
(CHEMBL1084933 | {4-[1-(2-Fluoro-phenyl)-2,2-dioxo-...)Show InChI InChI=1S/C18H22FN3O2S/c1-20-12-6-7-13-21-14-15-8-2-4-10-17(15)22(25(21,23)24)18-11-5-3-9-16(18)19/h2-5,8-11,20H,6-7,12-14H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313550
(CHEMBL1085198 | CHEMBL1204412 | {3-[1-(2,6-Difluor...)Show InChI InChI=1S/C18H20F2N2O2S/c1-21-11-5-7-14-12-13-6-2-3-10-17(13)22(25(14,23)24)18-15(19)8-4-9-16(18)20/h2-4,6,8-10,14,21H,5,7,11-12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313549
(CHEMBL1085197 | CHEMBL1204411 | {3-[1-(2-Fluoro-ph...)Show InChI InChI=1S/C18H21FN2O2S/c1-20-12-6-8-15-13-14-7-2-4-10-17(14)21(24(15,22)23)18-11-5-3-9-16(18)19/h2-5,7,9-11,15,20H,6,8,12-13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313548
(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)Show InChI InChI=1S/C18H22N2O2S/c1-19-13-7-11-17-14-15-8-5-6-12-18(15)20(23(17,21)22)16-9-3-2-4-10-16/h2-6,8-10,12,17,19H,7,11,13-14H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313552
(CHEMBL1096001 | CHEMBL1204414 | {3-[6-Fluoro-1-(2-...)Show InChI InChI=1S/C18H20F2N2O2S/c1-21-10-4-5-15-12-13-11-14(19)8-9-17(13)22(25(15,23)24)18-7-3-2-6-16(18)20/h2-3,6-9,11,15,21H,4-5,10,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313547
(CHEMBL1083211 | {4-[6-Fluoro-1-(2-fluoro-phenyl)-2...)Show InChI InChI=1S/C18H21F2N3O2S/c1-21-10-4-5-11-22-13-14-12-15(19)8-9-17(14)23(26(22,24)25)18-7-3-2-6-16(18)20/h2-3,6-9,12,21H,4-5,10-11,13H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313546
(CHEMBL1083210 | {3-[6-Fluoro-1-(2-fluoro-phenyl)-2...)Show InChI InChI=1S/C17H19F2N3O2S/c1-20-9-4-10-21-12-13-11-14(18)7-8-16(13)22(25(21,23)24)17-6-3-2-5-15(17)19/h2-3,5-8,11,20H,4,9-10,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313532
(CHEMBL1086398 | [3-(2,2-Dioxo-1-phenyl-1,4-dihydro...)Show InChI InChI=1S/C17H21N3O2S/c1-18-12-7-13-19-14-15-8-5-6-11-17(15)20(23(19,21)22)16-9-3-2-4-10-16/h2-6,8-11,18H,7,12-14H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313537
(CHEMBL1085906 | [3-(2,2-Dioxo-1-p-tolyl-1,4-dihydr...)Show InChI InChI=1S/C18H23N3O2S/c1-15-8-10-17(11-9-15)21-18-7-4-3-6-16(18)14-20(24(21,22)23)13-5-12-19-2/h3-4,6-11,19H,5,12-14H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313551
(CHEMBL1095367 | CHEMBL1204413 | [3-(6-Fluoro-2,2-d...)Show InChI InChI=1S/C18H21FN2O2S/c1-20-11-5-8-17-13-14-12-15(19)9-10-18(14)21(24(17,22)23)16-6-3-2-4-7-16/h2-4,6-7,9-10,12,17,20H,5,8,11,13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313542
(CHEMBL1087923 | {2-[1-(2-Fluoro-phenyl)-2,2-dioxo-...)Show InChI InChI=1S/C16H18FN3O2S/c1-18-10-11-19-12-13-6-2-4-8-15(13)20(23(19,21)22)16-9-5-3-7-14(16)17/h2-9,18H,10-12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313551
(CHEMBL1095367 | CHEMBL1204413 | [3-(6-Fluoro-2,2-d...)Show InChI InChI=1S/C18H21FN2O2S/c1-20-11-5-8-17-13-14-12-15(19)9-10-18(14)21(24(17,22)23)16-6-3-2-4-7-16/h2-4,6-7,9-10,12,17,20H,5,8,11,13H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313552
(CHEMBL1096001 | CHEMBL1204414 | {3-[6-Fluoro-1-(2-...)Show InChI InChI=1S/C18H20F2N2O2S/c1-21-10-4-5-15-12-13-11-14(19)8-9-17(13)22(25(15,23)24)18-7-3-2-6-16(18)20/h2-3,6-9,11,15,21H,4-5,10,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313536
(CHEMBL1085905 | {3-[1-(4-Fluoro-phenyl)-2,2-dioxo-...)Show InChI InChI=1S/C17H20FN3O2S/c1-19-11-4-12-20-13-14-5-2-3-6-17(14)21(24(20,22)23)16-9-7-15(18)8-10-16/h2-3,5-10,19H,4,11-13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313553
(CHEMBL1099373 | CHEMBL1204415 | {3-[1-(2,6-Difluor...)Show InChI InChI=1S/C18H19F3N2O2S/c1-22-9-3-4-14-11-12-10-13(19)7-8-17(12)23(26(14,24)25)18-15(20)5-2-6-16(18)21/h2,5-8,10,14,22H,3-4,9,11H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313533
(CHEMBL1086399 | {3-[1-(3-Fluoro-phenyl)-2,2-dioxo-...)Show InChI InChI=1S/C17H20FN3O2S/c1-19-10-5-11-20-13-14-6-2-3-9-17(14)21(24(20,22)23)16-8-4-7-15(18)12-16/h2-4,6-9,12,19H,5,10-11,13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313552
(CHEMBL1096001 | CHEMBL1204414 | {3-[6-Fluoro-1-(2-...)Show InChI InChI=1S/C18H20F2N2O2S/c1-21-10-4-5-15-12-13-11-14(19)8-9-17(13)22(25(15,23)24)18-7-3-2-6-16(18)20/h2-3,6-9,11,15,21H,4-5,10,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313535
(CHEMBL1085904 | {3-[1-(3-Methoxy-phenyl)-2,2-dioxo...)Show InChI InChI=1S/C18H23N3O3S/c1-19-11-6-12-20-14-15-7-3-4-10-18(15)21(25(20,22)23)16-8-5-9-17(13-16)24-2/h3-5,7-10,13,19H,6,11-12,14H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313539
(CHEMBL1077202 | {3-[1-(4-Chloro-phenyl)-2,2-dioxo-...)Show InChI InChI=1S/C17H20ClN3O2S/c1-19-11-4-12-20-13-14-5-2-3-6-17(14)21(24(20,22)23)16-9-7-15(18)8-10-16/h2-3,5-10,19H,4,11-13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313540
(CHEMBL1087921 | {3-[1-(3,4-Difluoro-phenyl)-2,2-di...)Show InChI InChI=1S/C17H19F2N3O2S/c1-20-9-4-10-21-12-13-5-2-3-6-17(13)22(25(21,23)24)14-7-8-15(18)16(19)11-14/h2-3,5-8,11,20H,4,9-10,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313534
(CHEMBL1082534 | [3-(2,2-Dioxo-1-m-tolyl-1,4-dihydr...)Show InChI InChI=1S/C18H23N3O2S/c1-15-7-5-9-17(13-15)21-18-10-4-3-8-16(18)14-20(24(21,22)23)12-6-11-19-2/h3-5,7-10,13,19H,6,11-12,14H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313545
(CHEMBL1084934 | {2-[6-Fluoro-1-(2-fluoro-phenyl)-2...)Show InChI InChI=1S/C16H17F2N3O2S/c1-19-8-9-20-11-12-10-13(17)6-7-15(12)21(24(20,22)23)16-5-3-2-4-14(16)18/h2-7,10,19H,8-9,11H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313541
(CHEMBL1087922 | {3-[1-(3-Chloro-4-fluoro-phenyl)-2...)Show InChI InChI=1S/C17H19ClFN3O2S/c1-20-9-4-10-21-12-13-5-2-3-6-17(13)22(25(21,23)24)14-7-8-16(19)15(18)11-14/h2-3,5-8,11,20H,4,9-10,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313546
(CHEMBL1083210 | {3-[6-Fluoro-1-(2-fluoro-phenyl)-2...)Show InChI InChI=1S/C17H19F2N3O2S/c1-20-9-4-10-21-12-13-11-14(18)7-8-16(13)22(25(21,23)24)17-6-3-2-5-15(17)19/h2-3,5-8,11,20H,4,9-10,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313544
(CHEMBL1084933 | {4-[1-(2-Fluoro-phenyl)-2,2-dioxo-...)Show InChI InChI=1S/C18H22FN3O2S/c1-20-12-6-7-13-21-14-15-8-2-4-10-17(15)22(25(21,23)24)18-11-5-3-9-16(18)19/h2-5,8-11,20H,6-7,12-14H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313548
(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)Show InChI InChI=1S/C18H22N2O2S/c1-19-13-7-11-17-14-15-8-5-6-12-18(15)20(23(17,21)22)16-9-3-2-4-10-16/h2-6,8-10,12,17,19H,7,11,13-14H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50313538
(CHEMBL1085907 | {3-[1-(4-Methoxy-phenyl)-2,2-dioxo...)Show InChI InChI=1S/C18H23N3O3S/c1-19-12-5-13-20-14-15-6-3-4-7-18(15)21(25(20,22)23)16-8-10-17(24-2)11-9-16/h3-4,6-11,19H,5,12-14H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50313551
(CHEMBL1095367 | CHEMBL1204413 | [3-(6-Fluoro-2,2-d...)Show InChI InChI=1S/C18H21FN2O2S/c1-20-11-5-8-17-13-14-12-15(19)9-10-18(14)21(24(17,22)23)16-6-3-2-4-7-16/h2-4,6-7,9-10,12,17,20H,5,8,11,13H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Displacement of [3H]WIN-35428 from human recombinant DAT expressed in CHO cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313543
(CHEMBL1087924 | {3-[1-(2-Fluoro-phenyl)-2,2-dioxo-...)Show InChI InChI=1S/C17H20FN3O2S/c1-19-11-6-12-20-13-14-7-2-4-9-16(14)21(24(20,22)23)17-10-5-3-8-15(17)18/h2-5,7-10,19H,6,11-13H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313532
(CHEMBL1086398 | [3-(2,2-Dioxo-1-phenyl-1,4-dihydro...)Show InChI InChI=1S/C17H21N3O2S/c1-18-12-7-13-19-14-15-8-5-6-11-17(15)20(23(19,21)22)16-9-3-2-4-10-16/h2-6,8-11,18H,7,12-14H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50313548
(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)Show InChI InChI=1S/C18H22N2O2S/c1-19-13-7-11-17-14-15-8-5-6-12-18(15)20(23(17,21)22)16-9-3-2-4-10-16/h2-6,8-10,12,17,19H,7,11,13-14H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Displacement of [3H]WIN-35428 from human recombinant DAT expressed in CHO cells |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313548
(CHEMBL1077209 | CHEMBL1204410 | [3-(2,2-Dioxo-1-ph...)Show InChI InChI=1S/C18H22N2O2S/c1-19-13-7-11-17-14-15-8-5-6-12-18(15)20(23(17,21)22)16-9-3-2-4-10-16/h2-6,8-10,12,17,19H,7,11,13-14H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313550
(CHEMBL1085198 | CHEMBL1204412 | {3-[1-(2,6-Difluor...)Show InChI InChI=1S/C18H20F2N2O2S/c1-21-11-5-7-14-12-13-6-2-3-10-17(13)22(25(14,23)24)18-15(19)8-4-9-16(18)20/h2-4,6,8-10,14,21H,5,7,11-12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50313545
(CHEMBL1084934 | {2-[6-Fluoro-1-(2-fluoro-phenyl)-2...)Show InChI InChI=1S/C16H17F2N3O2S/c1-19-8-9-20-11-12-10-13(17)6-7-15(12)21(24(20,22)23)16-5-3-2-4-14(16)18/h2-7,10,19H,8-9,11H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR |
Bioorg Med Chem Lett 20: 1555-8 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q |
More data for this Ligand-Target Pair | |