Compile Data Set for Download or QSAR

Found 57 hits Enz. Inhib. hit(s) with all data for entry = 50039375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336625 (5-bromo-N-(4-(2-chlorobenzamido)-3-methoxyphenyl)f...) Show SMILES COc1cc(NC(=O)c2ccc(Br)o2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C19H14BrClN2O4/c1-26-16-10-11(22-19(25)15-8-9-17(20)27-15)6-7-14(16)23-18(24)12-4-2-3-5-13(12)21/h2-10H,1H3,(H,22,25)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336617 (CHEMBL1672247 | N-(3-chloro-4-(2-fluorobenzamido)p...) Show SMILES Fc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C19H13ClFN3O2/c20-14-11-12(23-19(26)17-7-3-4-10-22-17)8-9-16(14)24-18(25)13-5-1-2-6-15(13)21/h1-11H,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.39E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM77724 (MLS000592149 | N-[(5-nitro-2-thienyl)methyleneamin...) Show SMILES [O-][N+](=O)c1ccc(\C=N\NC(=O)c2cccnc2)s1 Show InChI InChI=1S/C11H8N4O3S/c16-11(8-2-1-5-12-6-8)14-13-7-9-3-4-10(19-9)15(17)18/h1-7H,(H,14,16)/b13-7+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336628 (CHEMBL1672232 | N-(4-(2-chlorobenzamido)-3-methoxy...) Show SMILES COc1cc(NC(=O)c2nccs2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C18H14ClN3O3S/c1-25-15-10-11(21-17(24)18-20-8-9-26-18)6-7-14(15)22-16(23)12-4-2-3-5-13(12)19/h2-10H,1H3,(H,21,24)(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	627	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336629 (CHEMBL1672233 | N-(4-(2-chlorobenzamido)-3-methoxy...) Show SMILES COc1cc(NC(=O)c2cscn2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C18H14ClN3O3S/c1-25-16-8-11(21-18(24)15-9-26-10-20-15)6-7-14(16)22-17(23)12-4-2-3-5-13(12)19/h2-10H,1H3,(H,21,24)(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	845	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM55082 (N-[4-[(2-chlorobenzoyl)amino]-3-methoxy-phenyl]pic...) Show SMILES COc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C20H16ClN3O3/c1-27-18-12-13(23-20(26)17-8-4-5-11-22-17)9-10-16(18)24-19(25)14-6-2-3-7-15(14)21/h2-12H,1H3,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	99.5	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336630 (CHEMBL1672235 | N-(4-(2-chlorobenzamido)-3-methoxy...) Show SMILES COc1cc(NC(=O)c2cnccn2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C19H15ClN4O3/c1-27-17-10-12(23-19(26)16-11-21-8-9-22-16)6-7-15(17)24-18(25)13-4-2-3-5-14(13)20/h2-11H,1H3,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336631 (CHEMBL1672236 | N-(4-(2-chlorobenzamido)-3-methoxy...) Show SMILES COc1cc(NC(=O)c2ccncn2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C19H15ClN4O3/c1-27-17-10-12(23-19(26)16-8-9-21-11-22-16)6-7-15(17)24-18(25)13-4-2-3-5-14(13)20/h2-11H,1H3,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336632 (2-chloro-N-(4-(cyclohexanecarboxamido)-2-methoxyph...) Show SMILES COc1cc(NC(=O)C2CCCCC2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C21H23ClN2O3/c1-27-19-13-15(23-20(25)14-7-3-2-4-8-14)11-12-18(19)24-21(26)16-9-5-6-10-17(16)22/h5-6,9-14H,2-4,7-8H2,1H3,(H,23,25)(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50263669 ((1aS,7aS)-7-(hydroxyimino)-N-phenyl-1,1a,7,7a-tetr...) Show SMILES O=NC1[C@@H]2C[C@@]2(Oc2ccccc12)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C17H14N2O3/c20-16(18-11-6-2-1-3-7-11)17-10-13(17)15(19-21)12-8-4-5-9-14(12)22-17/h1-9,13,15H,10H2,(H,18,20)/t13-,15?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.74E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM55083 (N-[3-chloranyl-4-[(2-chlorophenyl)carbonylamino]ph...) Show SMILES Clc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C19H13Cl2N3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	517	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336633 (CHEMBL1672239 | N-(4-(2-chlorobenzamido)-3-(triflu...) Show SMILES FC(F)(F)c1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C20H13ClF3N3O2/c21-15-6-2-1-5-13(15)18(28)27-16-9-8-12(11-14(16)20(22,23)24)26-19(29)17-7-3-4-10-25-17/h1-11H,(H,26,29)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.09E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336634 (CHEMBL1672240 | N-(4-(2-chlorobenzamido)phenyl)pic...) Show SMILES Clc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1 Show InChI InChI=1S/C19H14ClN3O2/c20-16-6-2-1-5-15(16)18(24)22-13-8-10-14(11-9-13)23-19(25)17-7-3-4-12-21-17/h1-12H,(H,22,24)(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM55084 (N-[4-[(2-chlorobenzoyl)amino]-3-fluoro-phenyl]pico...) Show SMILES Fc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C19H13ClFN3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	556	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336635 (CHEMBL1672242 | N-(3-chloro-4-(2-methylbenzamido)p...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C20H16ClN3O2/c1-13-6-2-3-7-15(13)19(25)24-17-10-9-14(12-16(17)21)23-20(26)18-8-4-5-11-22-18/h2-12H,1H3,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	958	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336636 (CHEMBL1672243 | N-(3-chloro-4-(cyclohexanecarboxam...) Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1NC(=O)C1CCCCC1 Show InChI InChI=1S/C19H20ClN3O2/c20-15-12-14(22-19(25)17-8-4-5-11-21-17)9-10-16(15)23-18(24)13-6-2-1-3-7-13/h4-5,8-13H,1-3,6-7H2,(H,22,25)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	426	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336614 (CHEMBL1672244 | N-(4-benzamido-3-chlorophenyl)pico...) Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1 Show InChI InChI=1S/C19H14ClN3O2/c20-15-12-14(22-19(25)17-8-4-5-11-21-17)9-10-16(15)23-18(24)13-6-2-1-3-7-13/h1-12H,(H,22,25)(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	361	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336615 (CHEMBL1672245 | N-(3-chloro-4-(2-chloro-4-fluorobe...) Show SMILES Fc1ccc(C(=O)Nc2ccc(NC(=O)c3ccccn3)cc2Cl)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2FN3O2/c20-14-9-11(22)4-6-13(14)18(26)25-16-7-5-12(10-15(16)21)24-19(27)17-3-1-2-8-23-17/h1-10H,(H,24,27)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	114	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50378891 (CHEMBL1909430) Show SMILES Fc1ccc(C(=O)Nc2ccc(NC(=O)c3ccccn3)cc2Cl)c(F)c1 Show InChI InChI=1S/C19H12ClF2N3O2/c20-14-10-12(24-19(27)17-3-1-2-8-23-17)5-7-16(14)25-18(26)13-6-4-11(21)9-15(13)22/h1-10H,(H,24,27)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50378892 (CHEMBL1909431) Show SMILES Clc1cc(Cl)cc(c1)C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C19H12Cl3N3O2/c20-12-7-11(8-13(21)9-12)18(26)25-16-5-4-14(10-15(16)22)24-19(27)17-3-1-2-6-23-17/h1-10H,(H,24,27)(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50378893 (CHEMBL1909433) Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1cncs1 Show InChI InChI=1S/C16H11ClN4O2S/c17-11-7-10(20-15(22)13-3-1-2-6-19-13)4-5-12(11)21-16(23)14-8-18-9-24-14/h1-9H,(H,20,22)(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50378894 (CHEMBL1909434) Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1nccs1 Show InChI InChI=1S/C16H11ClN4O2S/c17-11-9-10(20-14(22)13-3-1-2-6-18-13)4-5-12(11)21-15(23)16-19-7-8-24-16/h1-9H,(H,20,22)(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	533	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50378895 (CHEMBL1909435) Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1cccs1 Show InChI InChI=1S/C17H12ClN3O2S/c18-12-10-11(20-16(22)14-4-1-2-8-19-14)6-7-13(12)21-17(23)15-5-3-9-24-15/h1-10H,(H,20,22)(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50378896 (CHEMBL1909436) Show SMILES Cn1c(cc2ccccc12)C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C22H17ClN4O2/c1-27-19-8-3-2-6-14(19)12-20(27)22(29)26-17-10-9-15(13-16(17)23)25-21(28)18-7-4-5-11-24-18/h2-13H,1H3,(H,25,28)(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.97E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50378897 (CHEMBL1909437) Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccc(o1)-c1ccccc1 Show InChI InChI=1S/C23H16ClN3O3/c24-17-14-16(26-22(28)19-8-4-5-13-25-19)9-10-18(17)27-23(29)21-12-11-20(30-21)15-6-2-1-3-7-15/h1-14H,(H,26,28)(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.35E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336623 (CHEMBL1672256 | N-(1-(2-chloro-4-fluorobenzoyl)-1H...) Show SMILES Fc1ccc(C(=O)n2ccc3cc(NC(=O)c4ccccn4)ccc23)c(Cl)c1 Show InChI InChI=1S/C21H13ClFN3O2/c22-17-12-14(23)4-6-16(17)21(28)26-10-8-13-11-15(5-7-19(13)26)25-20(27)18-3-1-2-9-24-18/h1-12H,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336624 (CHEMBL1672257 | N-(1-(2-methoxybenzoyl)-1H-indol-5...) Show SMILES COc1ccccc1C(=O)n1ccc2cc(NC(=O)c3ccccn3)ccc12 Show InChI InChI=1S/C22H17N3O3/c1-28-20-8-3-2-6-17(20)22(27)25-13-11-15-14-16(9-10-19(15)25)24-21(26)18-7-4-5-12-23-18/h2-14H,1H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336616 (CHEMBL1672246 | N-(3-chloro-4-isobutyramidophenyl)...) Show SMILES CC(C)C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C16H16ClN3O2/c1-10(2)15(21)20-13-7-6-11(9-12(13)17)19-16(22)14-5-3-4-8-18-14/h3-10H,1-2H3,(H,19,22)(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.27E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336617 (CHEMBL1672247 | N-(3-chloro-4-(2-fluorobenzamido)p...) Show SMILES Fc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C19H13ClFN3O2/c20-14-11-12(23-19(26)17-7-3-4-10-22-17)8-9-16(14)24-18(25)13-5-1-2-6-15(13)21/h1-11H,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50378892 (CHEMBL1909431) Show SMILES Clc1cc(Cl)cc(c1)C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C19H12Cl3N3O2/c20-12-7-11(8-13(21)9-12)18(26)25-16-5-4-14(10-15(16)22)24-19(27)17-3-1-2-6-23-17/h1-10H,(H,24,27)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50378893 (CHEMBL1909433) Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1cncs1 Show InChI InChI=1S/C16H11ClN4O2S/c17-11-7-10(20-15(22)13-3-1-2-6-19-13)4-5-12(11)21-16(23)14-8-18-9-24-14/h1-9H,(H,20,22)(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.18E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50378894 (CHEMBL1909434) Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1nccs1 Show InChI InChI=1S/C16H11ClN4O2S/c17-11-9-10(20-14(22)13-3-1-2-6-18-13)4-5-12(11)21-15(23)16-19-7-8-24-16/h1-9H,(H,20,22)(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	403	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50378895 (CHEMBL1909435) Show SMILES Clc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1cccs1 Show InChI InChI=1S/C17H12ClN3O2S/c18-12-10-11(20-16(22)14-4-1-2-8-19-14)6-7-13(12)21-17(23)15-5-3-9-24-15/h1-10H,(H,20,22)(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50378896 (CHEMBL1909436) Show SMILES Cn1c(cc2ccccc12)C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C22H17ClN4O2/c1-27-19-8-3-2-6-14(19)12-20(27)22(29)26-17-10-9-15(13-16(17)23)25-21(28)18-7-4-5-11-24-18/h2-13H,1H3,(H,25,28)(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.72E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336623 (CHEMBL1672256 | N-(1-(2-chloro-4-fluorobenzoyl)-1H...) Show SMILES Fc1ccc(C(=O)n2ccc3cc(NC(=O)c4ccccn4)ccc23)c(Cl)c1 Show InChI InChI=1S/C21H13ClFN3O2/c22-17-12-14(23)4-6-16(17)21(28)26-10-8-13-11-15(5-7-19(13)26)25-20(27)18-3-1-2-9-24-18/h1-12H,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50336624 (CHEMBL1672257 | N-(1-(2-methoxybenzoyl)-1H-indol-5...) Show SMILES COc1ccccc1C(=O)n1ccc2cc(NC(=O)c3ccccn3)ccc12 Show InChI InChI=1S/C22H17N3O3/c1-28-20-8-3-2-6-17(20)22(27)25-13-11-15-14-16(9-10-19(15)25)24-21(26)18-7-4-5-12-23-18/h2-14H,1H3,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336625 (5-bromo-N-(4-(2-chlorobenzamido)-3-methoxyphenyl)f...) Show SMILES COc1cc(NC(=O)c2ccc(Br)o2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C19H14BrClN2O4/c1-26-16-10-11(22-19(25)15-8-9-17(20)27-15)6-7-14(16)23-18(24)12-4-2-3-5-13(12)21/h2-10H,1H3,(H,22,25)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336626 (CHEMBL1385271 | N-(4-(2-chlorobenzamido)-3-methoxy...) Show SMILES COc1cc(NC(=O)c2ccco2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C19H15ClN2O4/c1-25-17-11-12(21-19(24)16-7-4-10-26-16)8-9-15(17)22-18(23)13-5-2-3-6-14(13)20/h2-11H,1H3,(H,21,24)(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336627 (CHEMBL1672231 | N-(4-(2-chlorobenzamido)-3-methoxy...) Show SMILES COc1cc(NC(=O)C2CCCO2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C19H19ClN2O4/c1-25-17-11-12(21-19(24)16-7-4-10-26-16)8-9-15(17)22-18(23)13-5-2-3-6-14(13)20/h2-3,5-6,8-9,11,16H,4,7,10H2,1H3,(H,21,24)(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM77724 (MLS000592149 | N-[(5-nitro-2-thienyl)methyleneamin...) Show SMILES [O-][N+](=O)c1ccc(\C=N\NC(=O)c2cccnc2)s1 Show InChI InChI=1S/C11H8N4O3S/c16-11(8-2-1-5-12-6-8)14-13-7-9-3-4-10(19-9)15(17)18/h1-7H,(H,14,16)/b13-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	860	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336628 (CHEMBL1672232 | N-(4-(2-chlorobenzamido)-3-methoxy...) Show SMILES COc1cc(NC(=O)c2nccs2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C18H14ClN3O3S/c1-25-15-10-11(21-17(24)18-20-8-9-26-18)6-7-14(15)22-16(23)12-4-2-3-5-13(12)19/h2-10H,1H3,(H,21,24)(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	377	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336629 (CHEMBL1672233 | N-(4-(2-chlorobenzamido)-3-methoxy...) Show SMILES COc1cc(NC(=O)c2cscn2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C18H14ClN3O3S/c1-25-16-8-11(21-18(24)15-9-26-10-20-15)6-7-14(16)22-17(23)12-4-2-3-5-13(12)19/h2-10H,1H3,(H,21,24)(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	753	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM55082 (N-[4-[(2-chlorobenzoyl)amino]-3-methoxy-phenyl]pic...) Show SMILES COc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C20H16ClN3O3/c1-27-18-12-13(23-20(26)17-8-4-5-11-22-17)9-10-16(18)24-19(25)14-6-2-3-7-15(14)21/h2-12H,1H3,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	106	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336630 (CHEMBL1672235 | N-(4-(2-chlorobenzamido)-3-methoxy...) Show SMILES COc1cc(NC(=O)c2cnccn2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C19H15ClN4O3/c1-27-17-10-12(23-19(26)16-11-21-8-9-22-16)6-7-15(17)24-18(25)13-4-2-3-5-14(13)20/h2-11H,1H3,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336631 (CHEMBL1672236 | N-(4-(2-chlorobenzamido)-3-methoxy...) Show SMILES COc1cc(NC(=O)c2ccncn2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C19H15ClN4O3/c1-27-17-10-12(23-19(26)16-8-9-21-11-22-16)6-7-15(17)24-18(25)13-4-2-3-5-14(13)20/h2-11H,1H3,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	894	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336632 (2-chloro-N-(4-(cyclohexanecarboxamido)-2-methoxyph...) Show SMILES COc1cc(NC(=O)C2CCCCC2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C21H23ClN2O3/c1-27-19-13-15(23-20(25)14-7-3-2-4-8-14)11-12-18(19)24-21(26)16-9-5-6-10-17(16)22/h5-6,9-14H,2-4,7-8H2,1H3,(H,23,25)(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50263669 ((1aS,7aS)-7-(hydroxyimino)-N-phenyl-1,1a,7,7a-tetr...) Show SMILES O=NC1[C@@H]2C[C@@]2(Oc2ccccc12)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C17H14N2O3/c20-16(18-11-6-2-1-3-7-11)17-10-13(17)15(19-21)12-8-4-5-9-14(12)22-17/h1-9,13,15H,10H2,(H,18,20)/t13-,15?,17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM55083 (N-[3-chloranyl-4-[(2-chlorophenyl)carbonylamino]ph...) Show SMILES Clc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl Show InChI InChI=1S/C19H13Cl2N3O2/c20-14-6-2-1-5-13(14)18(25)24-16-9-8-12(11-15(16)21)23-19(26)17-7-3-4-10-22-17/h1-11H,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336633 (CHEMBL1672239 | N-(4-(2-chlorobenzamido)-3-(triflu...) Show SMILES FC(F)(F)c1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1ccccc1Cl Show InChI InChI=1S/C20H13ClF3N3O2/c21-15-6-2-1-5-13(15)18(28)27-16-9-8-12(11-14(16)20(22,23)24)26-19(29)17-7-3-4-10-25-17/h1-11H,(H,26,29)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.36E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50336634 (CHEMBL1672240 | N-(4-(2-chlorobenzamido)phenyl)pic...) Show SMILES Clc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1 Show InChI InChI=1S/C19H14ClN3O2/c20-16-6-2-1-5-15(16)18(24)22-13-8-10-14(11-9-13)23-19(25)17-7-3-4-12-21-17/h1-12H,(H,22,24)(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilization				J Med Chem 54: 1106-10 (2011) Article DOI: 10.1021/jm101271s BindingDB Entry DOI: 10.7270/Q27P90C1
					More data for this Ligand-Target Pair

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