Found 66 hits Enz. Inhib. hit(s) with all data for entry = 50043616 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50347750
(CHEMBL1802358)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2OCOc2c1 |w:13.15,c:11| Show InChI InChI=1S/C17H13N3O3/c21-16-13(8-11-6-7-14-15(9-11)23-10-22-14)19-17(20-16)18-12-4-2-1-3-5-12/h1-9H,10H2,(H2,18,19,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50443638
(CHEMBL3092863)Show SMILES NCCOCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:21.21,t:18| Show InChI InChI=1S/C25H30N4O7/c26-7-8-31-9-10-32-11-12-33-13-14-34-20-4-2-19(3-5-20)27-25-28-21(24(30)29-25)15-18-1-6-22-23(16-18)36-17-35-22/h1-6,15-16H,7-14,17,26H2,(H2,27,28,29,30) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50347750
(CHEMBL1802358)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2OCOc2c1 |w:13.15,c:11| Show InChI InChI=1S/C17H13N3O3/c21-16-13(8-11-6-7-14-15(9-11)23-10-22-14)19-17(20-16)18-12-4-2-1-3-5-12/h1-9H,10H2,(H2,18,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50347750
(CHEMBL1802358)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2OCOc2c1 |w:13.15,c:11| Show InChI InChI=1S/C17H13N3O3/c21-16-13(8-11-6-7-14-15(9-11)23-10-22-14)19-17(20-16)18-12-4-2-1-3-5-12/h1-9H,10H2,(H2,18,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50443639
(CHEMBL3092862)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C23H26N4O6/c24-7-8-29-9-10-30-11-12-31-18-4-2-17(3-5-18)25-23-26-19(22(28)27-23)13-16-1-6-20-21(14-16)33-15-32-20/h1-6,13-14H,7-12,15,24H2,(H2,25,26,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50443638
(CHEMBL3092863)Show SMILES NCCOCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:21.21,t:18| Show InChI InChI=1S/C25H30N4O7/c26-7-8-31-9-10-32-11-12-33-13-14-34-20-4-2-19(3-5-20)27-25-28-21(24(30)29-25)15-18-1-6-22-23(16-18)36-17-35-22/h1-6,15-16H,7-14,17,26H2,(H2,27,28,29,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50443638
(CHEMBL3092863)Show SMILES NCCOCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:21.21,t:18| Show InChI InChI=1S/C25H30N4O7/c26-7-8-31-9-10-32-11-12-33-13-14-34-20-4-2-19(3-5-20)27-25-28-21(24(30)29-25)15-18-1-6-22-23(16-18)36-17-35-22/h1-6,15-16H,7-14,17,26H2,(H2,27,28,29,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50443638
(CHEMBL3092863)Show SMILES NCCOCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:21.21,t:18| Show InChI InChI=1S/C25H30N4O7/c26-7-8-31-9-10-32-11-12-33-13-14-34-20-4-2-19(3-5-20)27-25-28-21(24(30)29-25)15-18-1-6-22-23(16-18)36-17-35-22/h1-6,15-16H,7-14,17,26H2,(H2,27,28,29,30) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1B expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50443639
(CHEMBL3092862)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C23H26N4O6/c24-7-8-29-9-10-30-11-12-31-18-4-2-17(3-5-18)25-23-26-19(22(28)27-23)13-16-1-6-20-21(14-16)33-15-32-20/h1-6,13-14H,7-12,15,24H2,(H2,25,26,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50347750
(CHEMBL1802358)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2OCOc2c1 |w:13.15,c:11| Show InChI InChI=1S/C17H13N3O3/c21-16-13(8-11-6-7-14-15(9-11)23-10-22-14)19-17(20-16)18-12-4-2-1-3-5-12/h1-9H,10H2,(H2,18,19,20,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1B expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50443639
(CHEMBL3092862)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C23H26N4O6/c24-7-8-29-9-10-30-11-12-31-18-4-2-17(3-5-18)25-23-26-19(22(28)27-23)13-16-1-6-20-21(14-16)33-15-32-20/h1-6,13-14H,7-12,15,24H2,(H2,25,26,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50443639
(CHEMBL3092862)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C23H26N4O6/c24-7-8-29-9-10-30-11-12-31-18-4-2-17(3-5-18)25-23-26-19(22(28)27-23)13-16-1-6-20-21(14-16)33-15-32-20/h1-6,13-14H,7-12,15,24H2,(H2,25,26,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1B expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50443638
(CHEMBL3092863)Show SMILES NCCOCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:21.21,t:18| Show InChI InChI=1S/C25H30N4O7/c26-7-8-31-9-10-32-11-12-33-13-14-34-20-4-2-19(3-5-20)27-25-28-21(24(30)29-25)15-18-1-6-22-23(16-18)36-17-35-22/h1-6,15-16H,7-14,17,26H2,(H2,27,28,29,30) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50443639
(CHEMBL3092862)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C23H26N4O6/c24-7-8-29-9-10-30-11-12-31-18-4-2-17(3-5-18)25-23-26-19(22(28)27-23)13-16-1-6-20-21(14-16)33-15-32-20/h1-6,13-14H,7-12,15,24H2,(H2,25,26,27,28) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 3
(Homo sapiens (Human)) | BDBM50443638
(CHEMBL3092863)Show SMILES NCCOCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:21.21,t:18| Show InChI InChI=1S/C25H30N4O7/c26-7-8-31-9-10-32-11-12-33-13-14-34-20-4-2-19(3-5-20)27-25-28-21(24(30)29-25)15-18-1-6-22-23(16-18)36-17-35-22/h1-6,15-16H,7-14,17,26H2,(H2,27,28,29,30) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK3 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 3
(Homo sapiens (Human)) | BDBM50443639
(CHEMBL3092862)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C23H26N4O6/c24-7-8-29-9-10-30-11-12-31-18-4-2-17(3-5-18)25-23-26-19(22(28)27-23)13-16-1-6-20-21(14-16)33-15-32-20/h1-6,13-14H,7-12,15,24H2,(H2,25,26,27,28) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK3 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50443638
(CHEMBL3092863)Show SMILES NCCOCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:21.21,t:18| Show InChI InChI=1S/C25H30N4O7/c26-7-8-31-9-10-32-11-12-33-13-14-34-20-4-2-19(3-5-20)27-25-28-21(24(30)29-25)15-18-1-6-22-23(16-18)36-17-35-22/h1-6,15-16H,7-14,17,26H2,(H2,27,28,29,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK2 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50347750
(CHEMBL1802358)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2OCOc2c1 |w:13.15,c:11| Show InChI InChI=1S/C17H13N3O3/c21-16-13(8-11-6-7-14-15(9-11)23-10-22-14)19-17(20-16)18-12-4-2-1-3-5-12/h1-9H,10H2,(H2,18,19,20,21) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50443639
(CHEMBL3092862)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C23H26N4O6/c24-7-8-29-9-10-30-11-12-31-18-4-2-17(3-5-18)25-23-26-19(22(28)27-23)13-16-1-6-20-21(14-16)33-15-32-20/h1-6,13-14H,7-12,15,24H2,(H2,25,26,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK2 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50347750
(CHEMBL1802358)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2OCOc2c1 |w:13.15,c:11| Show InChI InChI=1S/C17H13N3O3/c21-16-13(8-11-6-7-14-15(9-11)23-10-22-14)19-17(20-16)18-12-4-2-1-3-5-12/h1-9H,10H2,(H2,18,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK2 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK3
(Mus musculus) | BDBM50443638
(CHEMBL3092863)Show SMILES NCCOCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:21.21,t:18| Show InChI InChI=1S/C25H30N4O7/c26-7-8-31-9-10-32-11-12-33-13-14-34-20-4-2-19(3-5-20)27-25-28-21(24(30)29-25)15-18-1-6-22-23(16-18)36-17-35-22/h1-6,15-16H,7-14,17,26H2,(H2,27,28,29,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK3 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 3
(Homo sapiens (Human)) | BDBM50347750
(CHEMBL1802358)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2OCOc2c1 |w:13.15,c:11| Show InChI InChI=1S/C17H13N3O3/c21-16-13(8-11-6-7-14-15(9-11)23-10-22-14)19-17(20-16)18-12-4-2-1-3-5-12/h1-9H,10H2,(H2,18,19,20,21) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK3 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK3
(Mus musculus) | BDBM50443639
(CHEMBL3092862)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C23H26N4O6/c24-7-8-29-9-10-30-11-12-31-18-4-2-17(3-5-18)25-23-26-19(22(28)27-23)13-16-1-6-20-21(14-16)33-15-32-20/h1-6,13-14H,7-12,15,24H2,(H2,25,26,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 810 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK3 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK3
(Mus musculus) | BDBM50347750
(CHEMBL1802358)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2OCOc2c1 |w:13.15,c:11| Show InChI InChI=1S/C17H13N3O3/c21-16-13(8-11-6-7-14-15(9-11)23-10-22-14)19-17(20-16)18-12-4-2-1-3-5-12/h1-9H,10H2,(H2,18,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK3 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50443638
(CHEMBL3092863)Show SMILES NCCOCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:21.21,t:18| Show InChI InChI=1S/C25H30N4O7/c26-7-8-31-9-10-32-11-12-33-13-14-34-20-4-2-19(3-5-20)27-25-28-21(24(30)29-25)15-18-1-6-22-23(16-18)36-17-35-22/h1-6,15-16H,7-14,17,26H2,(H2,27,28,29,30) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK9/cyclin T using YSPTSPSYSPTSPSYSPTSPSKKKK as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50443639
(CHEMBL3092862)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C23H26N4O6/c24-7-8-29-9-10-30-11-12-31-18-4-2-17(3-5-18)25-23-26-19(22(28)27-23)13-16-1-6-20-21(14-16)33-15-32-20/h1-6,13-14H,7-12,15,24H2,(H2,25,26,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK9/cyclin T using YSPTSPSYSPTSPSYSPTSPSKKKK as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50443637
(CHEMBL3092864)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccccc3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C22H26N4O4/c23-10-11-28-12-13-29-14-15-30-19-8-6-18(7-9-19)24-22-25-20(21(27)26-22)16-17-4-2-1-3-5-17/h1-9,16H,10-15,23H2,(H2,24,25,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK3
(Mus musculus) | BDBM50443637
(CHEMBL3092864)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccccc3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C22H26N4O4/c23-10-11-28-12-13-29-14-15-30-19-8-6-18(7-9-19)24-22-25-20(21(27)26-22)16-17-4-2-1-3-5-17/h1-9,16H,10-15,23H2,(H2,24,25,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK3 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK3
(Mus musculus) | BDBM50443640
(CHEMBL3092861)Show InChI InChI=1S/C6H15NO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-7H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK3 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK3
(Mus musculus) | BDBM50443641
(CHEMBL3092860)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccccc1 |w:13.15,c:11| Show InChI InChI=1S/C16H13N3O/c20-15-14(11-12-7-3-1-4-8-12)18-16(19-15)17-13-9-5-2-6-10-13/h1-11H,(H2,17,18,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK3 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50443637
(CHEMBL3092864)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccccc3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C22H26N4O4/c23-10-11-28-12-13-29-14-15-30-19-8-6-18(7-9-19)24-22-25-20(21(27)26-22)16-17-4-2-1-3-5-17/h1-9,16H,10-15,23H2,(H2,24,25,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK2 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50443641
(CHEMBL3092860)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccccc1 |w:13.15,c:11| Show InChI InChI=1S/C16H13N3O/c20-15-14(11-12-7-3-1-4-8-12)18-16(19-15)17-13-9-5-2-6-10-13/h1-11H,(H2,17,18,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK2 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50443637
(CHEMBL3092864)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccccc3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C22H26N4O4/c23-10-11-28-12-13-29-14-15-30-19-8-6-18(7-9-19)24-22-25-20(21(27)26-22)16-17-4-2-1-3-5-17/h1-9,16H,10-15,23H2,(H2,24,25,26,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50443640
(CHEMBL3092861)Show InChI InChI=1S/C6H15NO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-7H2 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50443641
(CHEMBL3092860)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccccc1 |w:13.15,c:11| Show InChI InChI=1S/C16H13N3O/c20-15-14(11-12-7-3-1-4-8-12)18-16(19-15)17-13-9-5-2-6-10-13/h1-11H,(H2,17,18,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50443637
(CHEMBL3092864)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccccc3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C22H26N4O4/c23-10-11-28-12-13-29-14-15-30-19-8-6-18(7-9-19)24-22-25-20(21(27)26-22)16-17-4-2-1-3-5-17/h1-9,16H,10-15,23H2,(H2,24,25,26,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK9/cyclin T using YSPTSPSYSPTSPSYSPTSPSKKKK as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50443640
(CHEMBL3092861)Show InChI InChI=1S/C6H15NO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK9/cyclin T using YSPTSPSYSPTSPSYSPTSPSKKKK as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50443641
(CHEMBL3092860)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccccc1 |w:13.15,c:11| Show InChI InChI=1S/C16H13N3O/c20-15-14(11-12-7-3-1-4-8-12)18-16(19-15)17-13-9-5-2-6-10-13/h1-11H,(H2,17,18,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK9/cyclin T using YSPTSPSYSPTSPSYSPTSPSKKKK as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50347750
(CHEMBL1802358)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2OCOc2c1 |w:13.15,c:11| Show InChI InChI=1S/C17H13N3O3/c21-16-13(8-11-6-7-14-15(9-11)23-10-22-14)19-17(20-16)18-12-4-2-1-3-5-12/h1-9H,10H2,(H2,18,19,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK9/cyclin T using YSPTSPSYSPTSPSYSPTSPSKKKK as substrate |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50443637
(CHEMBL3092864)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccccc3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C22H26N4O4/c23-10-11-28-12-13-29-14-15-30-19-8-6-18(7-9-19)24-22-25-20(21(27)26-22)16-17-4-2-1-3-5-17/h1-9,16H,10-15,23H2,(H2,24,25,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using [gamma-33P]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50443638
(CHEMBL3092863)Show SMILES NCCOCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:21.21,t:18| Show InChI InChI=1S/C25H30N4O7/c26-7-8-31-9-10-32-11-12-33-13-14-34-20-4-2-19(3-5-20)27-25-28-21(24(30)29-25)15-18-1-6-22-23(16-18)36-17-35-22/h1-6,15-16H,7-14,17,26H2,(H2,27,28,29,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using [gamma-33P]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50443639
(CHEMBL3092862)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C23H26N4O6/c24-7-8-29-9-10-30-11-12-31-18-4-2-17(3-5-18)25-23-26-19(22(28)27-23)13-16-1-6-20-21(14-16)33-15-32-20/h1-6,13-14H,7-12,15,24H2,(H2,25,26,27,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using [gamma-33P]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50443640
(CHEMBL3092861)Show InChI InChI=1S/C6H15NO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-7H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using [gamma-33P]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50443641
(CHEMBL3092860)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccccc1 |w:13.15,c:11| Show InChI InChI=1S/C16H13N3O/c20-15-14(11-12-7-3-1-4-8-12)18-16(19-15)17-13-9-5-2-6-10-13/h1-11H,(H2,17,18,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using [gamma-33P]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50347750
(CHEMBL1802358)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2OCOc2c1 |w:13.15,c:11| Show InChI InChI=1S/C17H13N3O3/c21-16-13(8-11-6-7-14-15(9-11)23-10-22-14)19-17(20-16)18-12-4-2-1-3-5-12/h1-9H,10H2,(H2,18,19,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using [gamma-33P]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50443638
(CHEMBL3092863)Show SMILES NCCOCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:21.21,t:18| Show InChI InChI=1S/C25H30N4O7/c26-7-8-31-9-10-32-11-12-33-13-14-34-20-4-2-19(3-5-20)27-25-28-21(24(30)29-25)15-18-1-6-22-23(16-18)36-17-35-22/h1-6,15-16H,7-14,17,26H2,(H2,27,28,29,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK2/cyclin A using [gamma-33P]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50443639
(CHEMBL3092862)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C23H26N4O6/c24-7-8-29-9-10-30-11-12-31-18-4-2-17(3-5-18)25-23-26-19(22(28)27-23)13-16-1-6-20-21(14-16)33-15-32-20/h1-6,13-14H,7-12,15,24H2,(H2,25,26,27,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK2/cyclin A using [gamma-33P]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50443640
(CHEMBL3092861)Show InChI InChI=1S/C6H15NO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-7H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK2/cyclin A using [gamma-33P]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50443637
(CHEMBL3092864)Show SMILES NCCOCCOCCOc1ccc(NC2=NC(=Cc3ccccc3)C(=O)N2)cc1 |w:18.18,t:15| Show InChI InChI=1S/C22H26N4O4/c23-10-11-28-12-13-29-14-15-30-19-8-6-18(7-9-19)24-22-25-20(21(27)26-22)16-17-4-2-1-3-5-17/h1-9,16H,10-15,23H2,(H2,24,25,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK2/cyclin A using [gamma-33P]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50347750
(CHEMBL1802358)Show SMILES O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2OCOc2c1 |w:13.15,c:11| Show InChI InChI=1S/C17H13N3O3/c21-16-13(8-11-6-7-14-15(9-11)23-10-22-14)19-17(20-16)18-12-4-2-1-3-5-12/h1-9H,10H2,(H2,18,19,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Rennes 1
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK2/cyclin A using [gamma-33P]-ATP after 30 mins by scintillation counting |
Eur J Med Chem 62: 728-37 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.035 BindingDB Entry DOI: 10.7270/Q2T1553Q |
More data for this Ligand-Target Pair | |