Found 77 hits Enz. Inhib. hit(s) with all data for entry = 50003619 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473868
(CHEMBL339108)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1CCOCc1ccccc1)C2(C)C |THB:8:9:25:14.12.13,15:14:25:9.3.2| Show InChI InChI=1S/C24H31NO2/c1-23(2)22-16-19-20(10-7-11-21(19)26)24(23,3)12-13-25(22)14-15-27-17-18-8-5-4-6-9-18/h4-11,22,26H,12-17H2,1-3H3/t22-,24?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473870
(CHEMBL2112617)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23+,25?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473882
(CHEMBL126206)Show SMILES [H][C@@]12Cc3c(O)cccc3C(C)(CCN1CC(C)OCc1ccccc1)C2 |THB:15:14:3.9.2:26,8:9:26:14.12.13| Show InChI InChI=1S/C23H29NO2/c1-17(26-16-18-7-4-3-5-8-18)15-24-12-11-23(2)14-19(24)13-20-21(23)9-6-10-22(20)25/h3-10,17,19,25H,11-16H2,1-2H3/t17?,19-,23?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473876
(CHEMBL2112614)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C24H31NO2/c1-17(27-16-19-8-5-4-6-9-19)15-25-13-12-24(3)18(2)22(25)14-20-21(24)10-7-11-23(20)26/h4-11,17-18,22,26H,12-16H2,1-3H3/t17-,18?,22+,24?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1S
(Rattus norvegicus) | BDBM50473868
(CHEMBL339108)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1CCOCc1ccccc1)C2(C)C |THB:8:9:25:14.12.13,15:14:25:9.3.2| Show InChI InChI=1S/C24H31NO2/c1-23(2)22-16-19-20(10-7-11-21(19)26)24(23,3)12-13-25(22)14-15-27-17-18-8-5-4-6-9-18/h4-11,22,26H,12-17H2,1-3H3/t22-,24?/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of verapamil from L-type calcium channel binding site |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473890
(CHEMBL2111820)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23-,25?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 114 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473866
(CHEMBL2112613)Show SMILES [H][C@]12Cc3cc(O)ccc3C(C)(CCN1C[C@H](C)Oc1ccccc1)C2(C)C |THB:8:9:25:14.12.13,15:14:25:9.3.2| Show InChI InChI=1S/C24H31NO2/c1-17(27-20-8-6-5-7-9-20)16-25-13-12-24(4)21-11-10-19(26)14-18(21)15-22(25)23(24,2)3/h5-11,14,17,22,26H,12-13,15-16H2,1-4H3/t17-,22+,24?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 149 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473883
(CHEMBL2111817)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@@H](C)OCc1ccccc1)C2C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C24H31NO2/c1-17(27-16-19-8-5-4-6-9-19)15-25-13-12-24(3)18(2)22(25)14-20-21(24)10-7-11-23(20)26/h4-11,17-18,22,26H,12-16H2,1-3H3/t17-,18?,22-,24?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 153 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50066066
((S)-1-[4-(Benzothiazol-2-yl-methyl-amino)-piperidi...)Show SMILES CN(C1CCN(C[C@H](O)COc2ccc(F)c(F)c2)CC1)c1nc2ccccc2s1 Show InChI InChI=1S/C22H25F2N3O2S/c1-26(22-25-20-4-2-3-5-21(20)30-22)15-8-10-27(11-9-15)13-16(28)14-29-17-6-7-18(23)19(24)12-17/h2-7,12,15-16,28H,8-11,13-14H2,1H3/t16-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 203 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473881
(CHEMBL2112615)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OCC1CCCCC1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H39NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h8,11-12,18-19,23,27H,5-7,9-10,13-17H2,1-4H3/t18-,23+,25?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 208 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1S
(Rattus norvegicus) | BDBM50473868
(CHEMBL339108)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1CCOCc1ccccc1)C2(C)C |THB:8:9:25:14.12.13,15:14:25:9.3.2| Show InChI InChI=1S/C24H31NO2/c1-23(2)22-16-19-20(10-7-11-21(19)26)24(23,3)12-13-25(22)14-15-27-17-18-8-5-4-6-9-18/h4-11,22,26H,12-17H2,1-3H3/t22-,24?/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 217 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of diltiazem from L-type calcium channel binding site |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473879
(CHEMBL2111818)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@@H](C)OCC1CCCCC1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H39NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h8,11-12,18-19,23,27H,5-7,9-10,13-17H2,1-4H3/t18-,23-,25?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 241 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473869
(Lifarizine | RS-87476-000)Show SMILES Cc1nc([nH]c1CN1CCN(CC1)C(c1ccccc1)c1ccccc1)-c1ccc(C)cc1 Show InChI InChI=1S/C29H32N4/c1-22-13-15-26(16-14-22)29-30-23(2)27(31-29)21-32-17-19-33(20-18-32)28(24-9-5-3-6-10-24)25-11-7-4-8-12-25/h3-16,28H,17-21H2,1-2H3,(H,30,31) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 259 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473875
(CHEMBL2111814)Show SMILES [H][C@]12Cc3cc(O)ccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2(C)C |THB:8:9:26:14.12.13,15:14:26:9.3.2| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-8-6-5-7-9-19)16-26-13-12-25(4)22-11-10-21(27)14-20(22)15-23(26)24(25,2)3/h5-11,14,18,23,27H,12-13,15-17H2,1-4H3/t18-,23+,25?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 312 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473894
(CHEMBL2112628)Show SMILES [H][C@]12Cc3cc(O)ccc3C(C)(CCN1C[C@@H](C)OCc1ccccc1)C2(C)C |THB:8:9:26:14.12.13,15:14:26:9.3.2| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-8-6-5-7-9-19)16-26-13-12-25(4)22-11-10-21(27)14-20(22)15-23(26)24(25,2)3/h5-11,14,18,23,27H,12-13,15-17H2,1-4H3/t18-,23-,25?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 382 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1S
(Rattus norvegicus) | BDBM50473890
(CHEMBL2111820)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23-,25?/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 391 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of diltiazem from L-type calcium channel binding site |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1S
(Rattus norvegicus) | BDBM50473870
(CHEMBL2112617)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23+,25?/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 449 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of verapamil from L-type calcium channel binding site |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1S
(Rattus norvegicus) | BDBM50473890
(CHEMBL2111820)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23-,25?/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of verapamil from L-type calcium channel binding site |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1S
(Rattus norvegicus) | BDBM50473870
(CHEMBL2112617)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23+,25?/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 660 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of diltiazem from L-type calcium channel binding site |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473888
(CHEMBL2111816)Show SMILES [H][C@]12Cc3cc(O)ccc3C(C)(CCN1C[C@@H](C)Oc1ccccc1)C2(C)C |THB:8:9:25:14.12.13,15:14:25:9.3.2| Show InChI InChI=1S/C24H31NO2/c1-17(27-20-8-6-5-7-9-20)16-25-13-12-24(4)21-11-10-19(26)14-18(21)15-22(25)23(24,2)3/h5-11,14,17,22,26H,12-13,15-16H2,1-4H3/t17-,22-,24?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 662 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473891
(CHEMBL2112624)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OC)C2(C)C |r,THB:15:14:20:9.3.2,8:9:20:14.12.13| Show InChI InChI=1S/C19H29NO2/c1-13(22-5)12-20-10-9-19(4)15-7-6-8-16(21)14(15)11-17(20)18(19,2)3/h6-8,13,17,21H,9-12H2,1-5H3/t13-,17+,19?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 783 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473872
(CHEMBL2111815)Show SMILES [H][C@@]12Cc3cc(O)ccc3C(C)(CCN1C[C@@H](C)Oc1ccccc1)C2(C)C |THB:8:9:25:14.12.13,15:14:25:9.3.2| Show InChI InChI=1S/C24H31NO2/c1-17(27-20-8-6-5-7-9-20)16-25-13-12-24(4)21-11-10-19(26)14-18(21)15-22(25)23(24,2)3/h5-11,14,17,22,26H,12-13,15-16H2,1-4H3/t17-,22+,24?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 864 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473880
(CHEMBL421078)Show SMILES [H][C@]12Cc3cc(O)ccc3C(C)(CCN1CCc1ccccc1)C2(C)C |THB:8:9:23:14.12.13,15:14:23:9.3.2| Show InChI InChI=1S/C23H29NO/c1-22(2)21-16-18-15-19(25)9-10-20(18)23(22,3)12-14-24(21)13-11-17-7-5-4-6-8-17/h4-10,15,21,25H,11-14,16H2,1-3H3/t21-,23?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473877
(CHEMBL2111813)Show SMILES [H][C@@]12Cc3cc(O)ccc3C(C)(CCN1C[C@@H](C)OCc1ccccc1)C2(C)C |THB:8:9:26:14.12.13,15:14:26:9.3.2| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-8-6-5-7-9-19)16-26-13-12-25(4)22-11-10-21(27)14-20(22)15-23(26)24(25,2)3/h5-11,14,18,23,27H,12-13,15-17H2,1-4H3/t18-,23+,25?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473889
(CHEMBL332216)Show SMILES [H][C@@]12Cc3cc(O)ccc3C(C)(CCN1CCc1ccccc1)C2(C)C |THB:8:9:23:14.12.13,15:14:23:9.3.2| Show InChI InChI=1S/C23H29NO/c1-22(2)21-16-18-15-19(25)9-10-20(18)23(22,3)12-14-24(21)13-11-17-7-5-4-6-8-17/h4-10,15,21,25H,11-14,16H2,1-3H3/t21-,23?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473887
(CHEMBL2112616)Show SMILES [H][C@@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23-,25?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473886
(CHEMBL2111819)Show SMILES [H][C@@]12Cc3c(O)cccc3C(C)(CCN1C[C@@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23+,25?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473878
(CHEMBL2112629)Show SMILES [H][C@@]12Cc3cc(O)ccc3C(C)(CCN1C[C@H](C)Oc1ccccc1)C2(C)C |THB:8:9:25:14.12.13,15:14:25:9.3.2| Show InChI InChI=1S/C24H31NO2/c1-17(27-20-8-6-5-7-9-20)16-25-13-12-24(4)21-11-10-19(26)14-18(21)15-22(25)23(24,2)3/h5-11,14,17,22,26H,12-13,15-16H2,1-4H3/t17-,22-,24?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473885
(CHEMBL2112618)Show SMILES [H][C@@]12Cc3cc(O)ccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2(C)C |THB:8:9:26:14.12.13,15:14:26:9.3.2| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-8-6-5-7-9-19)16-26-13-12-25(4)22-11-10-21(27)14-20(22)15-23(26)24(25,2)3/h5-11,14,18,23,27H,12-13,15-17H2,1-4H3/t18-,23-,25?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473873
(CHEMBL2111821)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@@H](C)OC)C2(C)C |r,THB:15:14:20:9.3.2,8:9:20:14.12.13| Show InChI InChI=1S/C19H29NO2/c1-13(22-5)12-20-10-9-19(4)15-7-6-8-16(21)14(15)11-17(20)18(19,2)3/h6-8,13,17,21H,9-12H2,1-5H3/t13-,17-,19?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 3.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50066430
(2-(4-Methyl-piperazin-1-yl)-5-(2,3,5-trichloro-phe...)Show SMILES CN1CCN(CC1)c1ncc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl Show InChI InChI=1S/C15H16Cl3N5/c1-22-2-4-23(5-3-22)15-20-8-11(14(19)21-15)10-6-9(16)7-12(17)13(10)18/h6-8H,2-5H2,1H3,(H2,19,20,21) | PDB
UniProtKB/SwissProt
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| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473874
(CHEMBL607229)Show SMILES [H][C@]12Cc3ccccc3C(C)(CCN1C[C@H](C)OC)C2(C)C |r,THB:14:13:19:8.2.3,7:8:19:13.11.12| Show InChI InChI=1S/C19H29NO/c1-14(21-5)13-20-11-10-19(4)16-9-7-6-8-15(16)12-17(20)18(19,2)3/h6-9,14,17H,10-13H2,1-5H3/t14-,17+,19?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50366613
(DEXTROMETHORPHAN)Show SMILES COc1ccc2C[C@H]3[C@H]4CCCC[C@@]4(CCN3C)c2c1 |r,THB:17:16:5.18.6:8| Show InChI InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank PC cid PC sid UniChem
Similars
| Article PubMed
| 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473884
(CHEMBL421633)Show SMILES [H][C@]12Cc3ccc(O)cc3C(C)(CCN1CC(C)OC)C2(C)C |THB:15:14:20:9.3.2,8:9:20:14.12.13| Show InChI InChI=1S/C19H29NO2/c1-13(22-5)12-20-9-8-19(4)16-11-15(21)7-6-14(16)10-17(20)18(19,2)3/h6-7,11,13,17,21H,8-10,12H2,1-5H3/t13?,17-,19?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 6.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473892
(CHEMBL125438)Show SMILES [H][C@]12Cc3cccc(O)c3C(C)(CCN1CC(C)OC)C2(C)C |THB:15:14:20:9.3.2,7:9:20:14.12.13| Show InChI InChI=1S/C19H29NO2/c1-13(22-5)12-20-10-9-19(4)17-14(7-6-8-15(17)21)11-16(20)18(19,2)3/h6-8,13,16,21H,9-12H2,1-5H3/t13?,16-,19?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1S
(Rattus norvegicus) | BDBM50473890
(CHEMBL2111820)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23-,25?/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of DHP from L-type calcium channel binding site |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473893
(CHEMBL122442)Show SMILES [H][C@@]12Cc3c(O)cccc3C(C)(CCN1C[C@@H](C)OC)C2(C)C |THB:15:14:20:9.3.2,8:9:20:14.12.13| Show InChI InChI=1S/C19H29NO2/c1-13(22-5)12-20-10-9-19(4)15-7-6-8-16(21)14(15)11-17(20)18(19,2)3/h6-8,13,17,21H,9-12H2,1-5H3/t13-,17+,19?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473868
(CHEMBL339108)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1CCOCc1ccccc1)C2(C)C |THB:8:9:25:14.12.13,15:14:25:9.3.2| Show InChI InChI=1S/C24H31NO2/c1-23(2)22-16-19-20(10-7-11-21(19)26)24(23,3)12-13-25(22)14-15-27-17-18-8-5-4-6-9-18/h4-11,22,26H,12-17H2,1-3H3/t22-,24?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]-TTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473870
(CHEMBL2112617)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23+,25?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]-TTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1S
(Rattus norvegicus) | BDBM50473870
(CHEMBL2112617)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23+,25?/m0/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of DHP from L-type calcium channel binding site |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473871
(CHEMBL607230)Show SMILES [H][C@@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OC)C2(C)C |r,THB:15:14:20:9.3.2,8:9:20:14.12.13| Show InChI InChI=1S/C19H29NO2/c1-13(22-5)12-20-10-9-19(4)15-7-6-8-16(21)14(15)11-17(20)18(19,2)3/h6-8,13,17,21H,9-12H2,1-5H3/t13-,17-,19?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1S
(Rattus norvegicus) | BDBM50473868
(CHEMBL339108)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1CCOCc1ccccc1)C2(C)C |THB:8:9:25:14.12.13,15:14:25:9.3.2| Show InChI InChI=1S/C24H31NO2/c1-23(2)22-16-19-20(10-7-11-21(19)26)24(23,3)12-13-25(22)14-15-27-17-18-8-5-4-6-9-18/h4-11,22,26H,12-17H2,1-3H3/t22-,24?/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of dihydropyridine (DHP) from the L-type calcium channel binding site |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473867
(CHEMBL333992)Show SMILES [H][C@]12Cc3cc(O)ccc3C(C)(CCN1CC(C)OC)C2(C)C |THB:8:9:20:14.12.13,15:14:20:9.3.2| Show InChI InChI=1S/C19H29NO2/c1-13(22-5)12-20-9-8-19(4)16-7-6-15(21)10-14(16)11-17(20)18(19,2)3/h6-7,10,13,17,21H,8-9,11-12H2,1-5H3/t13?,17-,19?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473890
(CHEMBL2111820)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23-,25?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]-TTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50117271
(1-(2,6-dimethylphenoxy)-2-propanolamine | 1-(2,6-d...)Show InChI InChI=1S/C11H17NO/c1-8-5-4-6-9(2)11(8)13-7-10(3)12/h4-6,10H,7,12H2,1-3H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 2.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473876
(CHEMBL2112614)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C24H31NO2/c1-17(27-16-19-8-5-4-6-9-19)15-25-13-12-24(3)18(2)22(25)14-20-21(24)10-7-11-23(20)26/h4-11,17-18,22,26H,12-16H2,1-3H3/t17-,18?,22+,24?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 134 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473882
(CHEMBL126206)Show SMILES [H][C@@]12Cc3c(O)cccc3C(C)(CCN1CC(C)OCc1ccccc1)C2 |THB:15:14:3.9.2:26,8:9:26:14.12.13| Show InChI InChI=1S/C23H29NO2/c1-17(26-16-18-7-4-3-5-8-18)15-24-12-11-23(2)14-19(24)13-20-21(23)9-6-10-22(20)25/h3-10,17,19,25H,11-16H2,1-2H3/t17?,19-,23?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 255 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473870
(CHEMBL2112617)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2(C)C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C25H33NO2/c1-18(28-17-19-9-6-5-7-10-19)16-26-14-13-25(4)21-11-8-12-22(27)20(21)15-23(26)24(25,2)3/h5-12,18,23,27H,13-17H2,1-4H3/t18-,23+,25?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 322 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473868
(CHEMBL339108)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1CCOCc1ccccc1)C2(C)C |THB:8:9:25:14.12.13,15:14:25:9.3.2| Show InChI InChI=1S/C24H31NO2/c1-23(2)22-16-19-20(10-7-11-21(19)26)24(23,3)12-13-25(22)14-15-27-17-18-8-5-4-6-9-18/h4-11,22,26H,12-17H2,1-3H3/t22-,24?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 379 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473883
(CHEMBL2111817)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@@H](C)OCc1ccccc1)C2C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C24H31NO2/c1-17(27-16-19-8-5-4-6-9-19)15-25-13-12-24(3)18(2)22(25)14-20-21(24)10-7-11-23(20)26/h4-11,17-18,22,26H,12-16H2,1-3H3/t17-,18?,22-,24?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 452 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this Ligand-Target Pair | |