Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50519874 (CHEMBL4582264) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using methylglyoxal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysis | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50519874 (CHEMBL4582264) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50519874 (CHEMBL4582264) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50519874 (CHEMBL4582264) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of human AKR1B1 expressed in Escherichia coli using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using by... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50519877 (CHEMBL4462469) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50080464 (ALR2 inhibitor, 12 | CHEMBL1405739) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 102 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of human AKR1B1 expressed in Escherichia coli using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using by... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50080464 (ALR2 inhibitor, 12 | CHEMBL1405739) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50519877 (CHEMBL4462469) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50519875 (CHEMBL4566195) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50080464 (ALR2 inhibitor, 12 | CHEMBL1405739) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 146 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using methylglyoxal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysis | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50080464 (ALR2 inhibitor, 12 | CHEMBL1405739) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 176 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50519874 (CHEMBL4582264) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 216 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using 4-hydroxynonenal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysis | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50519875 (CHEMBL4566195) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 233 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50519874 (CHEMBL4582264) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 292 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using 4-hydroxynonenal glutathione as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analy... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50519876 (CHEMBL4541343) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 434 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using H2O-dissolved compound by spect... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50080464 (ALR2 inhibitor, 12 | CHEMBL1405739) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 644 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using 4-hydroxynonenal as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analysis | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50519876 (CHEMBL4541343) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 787 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using 1% DMSO-dissolved compound by s... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Rattus norvegicus) | BDBM50080464 (ALR2 inhibitor, 12 | CHEMBL1405739) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of rat lens ALR2 using 4-hydroxynonenal glutathione as substrate incubated for 1 min and measured up to 4 mins by spectrophotometric analy... | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B10 (Homo sapiens (Human)) | BDBM50519874 (CHEMBL4582264) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.62E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Comenius University in Bratislava Curated by ChEMBL | Assay Description Inhibition of human AKR1B10 using D,L-glyceraldehyde as substrate incubated for 1 min and measured up to 4 mins using by spectrophotometric analysis | J Med Chem 63: 369-381 (2020) Article DOI: 10.1021/acs.jmedchem.9b01747 BindingDB Entry DOI: 10.7270/Q22F7RT7 | |||||||||||
More data for this Ligand-Target Pair |