Compile Data Set for Download or QSAR

Found 510 hits Enz. Inhib. hit(s) with all data for entry = 2712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376831 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES CO[C@@H]1CCN(C[C@H]1F)c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C28H33F2N5O2/c1-16-9-17(11-18(31)10-16)20-5-7-32-14-25(20)34-28(36)21-3-4-23(29)22-12-19(13-33-27(21)22)35-8-6-26(37-2)24(30)15-35/h3-5,7,12-14,16-18,24,26H,6,8-11,15,31H2,1-2H3,(H,34,36)/t16-,17+,18-,24+,26+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376832 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES COCCO[C@H]1CCN(C[C@@H]1F)c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C30H37F2N5O3/c1-18-11-19(13-20(33)12-18)22-5-7-34-16-27(22)36-30(38)23-3-4-25(31)24-14-21(15-35-29(23)24)37-8-6-28(26(32)17-37)40-10-9-39-2/h3-5,7,14-16,18-20,26,28H,6,8-13,17,33H2,1-2H3,(H,36,38)/t18-,19+,20-,26-,28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376832 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES COCCO[C@H]1CCN(C[C@@H]1F)c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C30H37F2N5O3/c1-18-11-19(13-20(33)12-18)22-5-7-34-16-27(22)36-30(38)23-3-4-25(31)24-14-21(15-35-29(23)24)37-8-6-28(26(32)17-37)40-10-9-39-2/h3-5,7,14-16,18-20,26,28H,6,8-13,17,33H2,1-2H3,(H,36,38)/t18-,19+,20-,26-,28-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376833 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](O)CN1c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C27H32FN5O2/c1-15-7-17(10-18(29)8-15)21-5-6-30-13-25(21)32-27(35)22-3-4-24(28)23-11-19(12-31-26(22)23)33-14-20(34)9-16(33)2/h3-6,11-13,15-18,20,34H,7-10,14,29H2,1-2H3,(H,32,35)/t15-,16+,17+,18-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376833 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](O)CN1c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C27H32FN5O2/c1-15-7-17(10-18(29)8-15)21-5-6-30-13-25(21)32-27(35)22-3-4-24(28)23-11-19(12-31-26(22)23)33-14-20(34)9-16(33)2/h3-6,11-13,15-18,20,34H,7-10,14,29H2,1-2H3,(H,32,35)/t15-,16+,17+,18-,20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376834 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES C[C@H]1C[C@H](O)CN1c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C27H32FN5O2/c1-15-7-17(10-18(29)8-15)21-5-6-30-13-25(21)32-27(35)22-3-4-24(28)23-11-19(12-31-26(22)23)33-14-20(34)9-16(33)2/h3-6,11-13,15-18,20,34H,7-10,14,29H2,1-2H3,(H,32,35)/t15-,16-,17+,18-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376834 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES C[C@H]1C[C@H](O)CN1c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C27H32FN5O2/c1-15-7-17(10-18(29)8-15)21-5-6-30-13-25(21)32-27(35)22-3-4-24(28)23-11-19(12-31-26(22)23)33-14-20(34)9-16(33)2/h3-6,11-13,15-18,20,34H,7-10,14,29H2,1-2H3,(H,32,35)/t15-,16-,17+,18-,20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376835 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES C[C@H]1CCN1c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C26H30FN5O/c1-15-9-17(11-18(28)10-15)20-5-7-29-14-24(20)31-26(33)21-3-4-23(27)22-12-19(13-30-25(21)22)32-8-6-16(32)2/h3-5,7,12-18H,6,8-11,28H2,1-2H3,(H,31,33)/t15-,16-,17+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376835 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES C[C@H]1CCN1c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C26H30FN5O/c1-15-9-17(11-18(28)10-15)20-5-7-29-14-24(20)31-26(33)21-3-4-23(27)22-12-19(13-30-25(21)22)32-8-6-16(32)2/h3-5,7,12-18H,6,8-11,28H2,1-2H3,(H,31,33)/t15-,16-,17+,18-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376836 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES C[C@@H]1CCN1c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C26H30FN5O/c1-15-9-17(11-18(28)10-15)20-5-7-29-14-24(20)31-26(33)21-3-4-23(27)22-12-19(13-30-25(21)22)32-8-6-16(32)2/h3-5,7,12-18H,6,8-11,28H2,1-2H3,(H,31,33)/t15-,16+,17+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376836 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES C[C@@H]1CCN1c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C26H30FN5O/c1-15-9-17(11-18(28)10-15)20-5-7-29-14-24(20)31-26(33)21-3-4-23(27)22-12-19(13-30-25(21)22)32-8-6-16(32)2/h3-5,7,12-18H,6,8-11,28H2,1-2H3,(H,31,33)/t15-,16+,17+,18-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376837 (Ethyl 4-(8-(4-((1R,3S,5S)-3-amino-5-methylcyclohex...) Show SMILES CCOC(=O)N1CCN(CC1)c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C29H35FN6O3/c1-3-39-29(38)36-10-8-35(9-11-36)21-15-24-25(30)5-4-23(27(24)33-16-21)28(37)34-26-17-32-7-6-22(26)19-12-18(2)13-20(31)14-19/h4-7,15-20H,3,8-14,31H2,1-2H3,(H,34,37)/t18-,19+,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376837 (Ethyl 4-(8-(4-((1R,3S,5S)-3-amino-5-methylcyclohex...) Show SMILES CCOC(=O)N1CCN(CC1)c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C29H35FN6O3/c1-3-39-29(38)36-10-8-35(9-11-36)21-15-24-25(30)5-4-23(27(24)33-16-21)28(37)34-26-17-32-7-6-22(26)19-12-18(2)13-20(31)14-19/h4-7,15-20H,3,8-14,31H2,1-2H3,(H,34,37)/t18-,19+,20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376838 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CCCC[C@H]1C |r| Show InChI InChI=1S/C28H34FN5O/c1-17-11-19(13-20(30)12-17)22-8-9-31-16-26(22)33-28(35)23-6-7-25(29)24-14-21(15-32-27(23)24)34-10-4-3-5-18(34)2/h6-9,14-20H,3-5,10-13,30H2,1-2H3,(H,33,35)/t17-,18+,19+,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376838 (N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CCCC[C@H]1C |r| Show InChI InChI=1S/C28H34FN5O/c1-17-11-19(13-20(30)12-17)22-8-9-31-16-26(22)33-28(35)23-6-7-25(29)24-14-21(15-32-27(23)24)34-10-4-3-5-18(34)2/h6-9,14-20H,3-5,10-13,30H2,1-2H3,(H,33,35)/t17-,18+,19+,20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376839 (US10450296, Example 170 | US11053215, Example 170 ...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CCCC[C@@H]1C |r| Show InChI InChI=1S/C28H34FN5O/c1-17-11-19(13-20(30)12-17)22-8-9-31-16-26(22)33-28(35)23-6-7-25(29)24-14-21(15-32-27(23)24)34-10-4-3-5-18(34)2/h6-9,14-20H,3-5,10-13,30H2,1-2H3,(H,33,35)/t17-,18-,19+,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376667 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES CCc1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C24H27FN4O/c1-3-15-10-20-21(25)5-4-19(23(20)28-12-15)24(30)29-22-13-27-7-6-18(22)16-8-14(2)9-17(26)11-16/h4-7,10,12-14,16-17H,3,8-9,11,26H2,1-2H3,(H,29,30)/t14-,16+,17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376667 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES CCc1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C24H27FN4O/c1-3-15-10-20-21(25)5-4-19(23(20)28-12-15)24(30)29-22-13-27-7-6-18(22)16-8-14(2)9-17(26)11-16/h4-7,10,12-14,16-17H,3,8-9,11,26H2,1-2H3,(H,29,30)/t14-,16+,17-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376668 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CCC[C@@H](F)C1 |r| Show InChI InChI=1S/C27H31F2N5O/c1-16-9-17(11-19(30)10-16)21-6-7-31-14-25(21)33-27(35)22-4-5-24(29)23-12-20(13-32-26(22)23)34-8-2-3-18(28)15-34/h4-7,12-14,16-19H,2-3,8-11,15,30H2,1H3,(H,33,35)/t16-,17+,18+,19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376668 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CCC[C@@H](F)C1 |r| Show InChI InChI=1S/C27H31F2N5O/c1-16-9-17(11-19(30)10-16)21-6-7-31-14-25(21)33-27(35)22-4-5-24(29)23-12-20(13-32-26(22)23)34-8-2-3-18(28)15-34/h4-7,12-14,16-19H,2-3,8-11,15,30H2,1H3,(H,33,35)/t16-,17+,18+,19-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376669 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CCCC1 |r| Show InChI InChI=1S/C26H30FN5O/c1-16-10-17(12-18(28)11-16)20-6-7-29-15-24(20)31-26(33)21-4-5-23(27)22-13-19(14-30-25(21)22)32-8-2-3-9-32/h4-7,13-18H,2-3,8-12,28H2,1H3,(H,31,33)/t16-,17+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376670 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CCC1 |r| Show InChI InChI=1S/C25H28FN5O/c1-15-9-16(11-17(27)10-15)19-5-6-28-14-23(19)30-25(32)20-3-4-22(26)21-12-18(13-29-24(20)21)31-7-2-8-31/h3-6,12-17H,2,7-11,27H2,1H3,(H,30,32)/t15-,16+,17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376671 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CC[C@H](F)C1 |r| Show InChI InChI=1S/C26H29F2N5O/c1-15-8-16(10-18(29)9-15)20-4-6-30-13-24(20)32-26(34)21-2-3-23(28)22-11-19(12-31-25(21)22)33-7-5-17(27)14-33/h2-4,6,11-13,15-18H,5,7-10,14,29H2,1H3,(H,32,34)/t15-,16+,17-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376671 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CC[C@H](F)C1 |r| Show InChI InChI=1S/C26H29F2N5O/c1-15-8-16(10-18(29)9-15)20-4-6-30-13-24(20)32-26(34)21-2-3-23(28)22-11-19(12-31-25(21)22)33-7-5-17(27)14-33/h2-4,6,11-13,15-18H,5,7-10,14,29H2,1H3,(H,32,34)/t15-,16+,17-,18-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376672 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CC[C@@H](F)C1 |r| Show InChI InChI=1S/C26H29F2N5O/c1-15-8-16(10-18(29)9-15)20-4-6-30-13-24(20)32-26(34)21-2-3-23(28)22-11-19(12-31-25(21)22)33-7-5-17(27)14-33/h2-4,6,11-13,15-18H,5,7-10,14,29H2,1H3,(H,32,34)/t15-,16+,17+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376672 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CC[C@@H](F)C1 |r| Show InChI InChI=1S/C26H29F2N5O/c1-15-8-16(10-18(29)9-15)20-4-6-30-13-24(20)32-26(34)21-2-3-23(28)22-11-19(12-31-25(21)22)33-7-5-17(27)14-33/h2-4,6,11-13,15-18H,5,7-10,14,29H2,1H3,(H,32,34)/t15-,16+,17+,18-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376673 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CC[C@@H](C1)C#N |r| Show InChI InChI=1S/C27H29FN6O/c1-16-8-18(10-19(30)9-16)21-4-6-31-14-25(21)33-27(35)22-2-3-24(28)23-11-20(13-32-26(22)23)34-7-5-17(12-29)15-34/h2-4,6,11,13-14,16-19H,5,7-10,15,30H2,1H3,(H,33,35)/t16-,17+,18+,19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376673 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CC[C@@H](C1)C#N |r| Show InChI InChI=1S/C27H29FN6O/c1-16-8-18(10-19(30)9-16)21-4-6-31-14-25(21)33-27(35)22-2-3-24(28)23-11-20(13-32-26(22)23)34-7-5-17(12-29)15-34/h2-4,6,11,13-14,16-19H,5,7-10,15,30H2,1H3,(H,33,35)/t16-,17+,18+,19-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376674 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CC[C@H](C1)C#N |r| Show InChI InChI=1S/C27H29FN6O/c1-16-8-18(10-19(30)9-16)21-4-6-31-14-25(21)33-27(35)22-2-3-24(28)23-11-20(13-32-26(22)23)34-7-5-17(12-29)15-34/h2-4,6,11,13-14,16-19H,5,7-10,15,30H2,1H3,(H,33,35)/t16-,17-,18+,19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376674 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CC[C@H](C1)C#N |r| Show InChI InChI=1S/C27H29FN6O/c1-16-8-18(10-19(30)9-16)21-4-6-31-14-25(21)33-27(35)22-2-3-24(28)23-11-20(13-32-26(22)23)34-7-5-17(12-29)15-34/h2-4,6,11,13-14,16-19H,5,7-10,15,30H2,1H3,(H,33,35)/t16-,17-,18+,19-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376675 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CC(F)C1 |r| Show InChI InChI=1S/C25H27F2N5O/c1-14-6-15(8-17(28)7-14)19-4-5-29-11-23(19)31-25(33)20-2-3-22(27)21-9-18(10-30-24(20)21)32-12-16(26)13-32/h2-5,9-11,14-17H,6-8,12-13,28H2,1H3,(H,31,33)/t14-,15+,17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376675 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CC(F)C1 |r| Show InChI InChI=1S/C25H27F2N5O/c1-14-6-15(8-17(28)7-14)19-4-5-29-11-23(19)31-25(33)20-2-3-22(27)21-9-18(10-30-24(20)21)32-12-16(26)13-32/h2-5,9-11,14-17H,6-8,12-13,28H2,1H3,(H,31,33)/t14-,15+,17-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376676 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CCOCC1 |r| Show InChI InChI=1S/C26H30FN5O2/c1-16-10-17(12-18(28)11-16)20-4-5-29-15-24(20)31-26(33)21-2-3-23(27)22-13-19(14-30-25(21)22)32-6-8-34-9-7-32/h2-5,13-18H,6-12,28H2,1H3,(H,31,33)/t16-,17+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376676 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)N1CCOCC1 |r| Show InChI InChI=1S/C26H30FN5O2/c1-16-10-17(12-18(28)11-16)20-4-5-29-15-24(20)31-26(33)21-2-3-23(27)22-13-19(14-30-25(21)22)32-6-8-34-9-7-32/h2-5,13-18H,6-12,28H2,1H3,(H,31,33)/t16-,17+,18-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376677 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES CO[C@H]1CCCN(C1)c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C28H34FN5O2/c1-17-10-18(12-19(30)11-17)22-7-8-31-15-26(22)33-28(35)23-5-6-25(29)24-13-20(14-32-27(23)24)34-9-3-4-21(16-34)36-2/h5-8,13-15,17-19,21H,3-4,9-12,16,30H2,1-2H3,(H,33,35)/t17-,18+,19-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376677 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES CO[C@H]1CCCN(C1)c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C28H34FN5O2/c1-17-10-18(12-19(30)11-17)22-7-8-31-15-26(22)33-28(35)23-5-6-25(29)24-13-20(14-32-27(23)24)34-9-3-4-21(16-34)36-2/h5-8,13-15,17-19,21H,3-4,9-12,16,30H2,1-2H3,(H,33,35)/t17-,18+,19-,21-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376678 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES CO[C@@H]1CCCN(C1)c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C28H34FN5O2/c1-17-10-18(12-19(30)11-17)22-7-8-31-15-26(22)33-28(35)23-5-6-25(29)24-13-20(14-32-27(23)24)34-9-3-4-21(16-34)36-2/h5-8,13-15,17-19,21H,3-4,9-12,16,30H2,1-2H3,(H,33,35)/t17-,18+,19-,21+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376678 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES CO[C@@H]1CCCN(C1)c1cnc2c(ccc(F)c2c1)C(=O)Nc1cnccc1[C@@H]1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C28H34FN5O2/c1-17-10-18(12-19(30)11-17)22-7-8-31-15-26(22)33-28(35)23-5-6-25(29)24-13-20(14-32-27(23)24)34-9-3-4-21(16-34)36-2/h5-8,13-15,17-19,21H,3-4,9-12,16,30H2,1-2H3,(H,33,35)/t17-,18+,19-,21+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376679 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)C1CC1 |r| Show InChI InChI=1S/C25H27FN4O/c1-14-8-16(10-18(27)9-14)19-6-7-28-13-23(19)30-25(31)20-4-5-22(26)21-11-17(15-2-3-15)12-29-24(20)21/h4-7,11-16,18H,2-3,8-10,27H2,1H3,(H,30,31)/t14-,16+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376679 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)C1CC1 |r| Show InChI InChI=1S/C25H27FN4O/c1-14-8-16(10-18(27)9-14)19-6-7-28-13-23(19)30-25(31)20-4-5-22(26)21-11-17(15-2-3-15)12-29-24(20)21/h4-7,11-16,18H,2-3,8-10,27H2,1H3,(H,30,31)/t14-,16+,18-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376680 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)C#CC1CC1 |r| Show InChI InChI=1S/C27H27FN4O/c1-16-10-19(13-20(29)11-16)21-8-9-30-15-25(21)32-27(33)22-6-7-24(28)23-12-18(14-31-26(22)23)5-4-17-2-3-17/h6-9,12,14-17,19-20H,2-3,10-11,13,29H2,1H3,(H,32,33)/t16-,19+,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376680 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)C#CC1CC1 |r| Show InChI InChI=1S/C27H27FN4O/c1-16-10-19(13-20(29)11-16)21-8-9-30-15-25(21)32-27(33)22-6-7-24(28)23-12-18(14-31-26(22)23)5-4-17-2-3-17/h6-9,12,14-17,19-20H,2-3,10-11,13,29H2,1H3,(H,32,33)/t16-,19+,20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376682 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C29H25F2N5O/c1-16-9-18(11-20(33)10-16)21-7-8-34-15-26(21)36-29(37)22-5-6-24(30)23-12-19(14-35-28(22)23)27-17(13-32)3-2-4-25(27)31/h2-8,12,14-16,18,20H,9-11,33H2,1H3,(H,36,37)/t16-,18+,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376682 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)-c1c(F)cccc1C#N |r| Show InChI InChI=1S/C29H25F2N5O/c1-16-9-18(11-20(33)10-16)21-7-8-34-15-26(21)36-29(37)22-5-6-24(30)23-12-19(14-35-28(22)23)27-17(13-32)3-2-4-25(27)31/h2-8,12,14-16,18,20H,9-11,33H2,1H3,(H,36,37)/t16-,18+,20-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376683 (Tert-Butyl {(1S,3R,5S)-3-[3-({[3-(2,6-difluorophen...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)-c1c(F)cccc1F |r| Show InChI InChI=1S/C28H25F3N4O/c1-15-9-16(11-18(32)10-15)19-7-8-33-14-25(19)35-28(36)20-5-6-22(29)21-12-17(13-34-27(20)21)26-23(30)3-2-4-24(26)31/h2-8,12-16,18H,9-11,32H2,1H3,(H,35,36)/t15-,16+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376683 (Tert-Butyl {(1S,3R,5S)-3-[3-({[3-(2,6-difluorophen...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)-c1c(F)cccc1F |r| Show InChI InChI=1S/C28H25F3N4O/c1-15-9-16(11-18(32)10-15)19-7-8-33-14-25(19)35-28(36)20-5-6-22(29)21-12-17(13-34-27(20)21)26-23(30)3-2-4-24(26)31/h2-8,12-16,18H,9-11,32H2,1H3,(H,35,36)/t15-,16+,18-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376684 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)-c1ccccc1C#N |r| Show InChI InChI=1S/C29H26FN5O/c1-17-10-19(12-21(32)11-17)23-8-9-33-16-27(23)35-29(36)24-6-7-26(30)25-13-20(15-34-28(24)25)22-5-3-2-4-18(22)14-31/h2-9,13,15-17,19,21H,10-12,32H2,1H3,(H,35,36)/t17-,19+,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376684 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)-c1ccccc1C#N |r| Show InChI InChI=1S/C29H26FN5O/c1-17-10-19(12-21(32)11-17)23-8-9-33-16-27(23)35-29(36)24-6-7-26(30)25-13-20(15-34-28(24)25)22-5-3-2-4-18(22)14-31/h2-9,13,15-17,19,21H,10-12,32H2,1H3,(H,35,36)/t17-,19+,21-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM376685 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)-c1c(F)cc(O)cc1F |r| Show InChI InChI=1S/C28H25F3N4O2/c1-14-6-15(8-17(32)7-14)19-4-5-33-13-25(19)35-28(37)20-2-3-22(29)21-9-16(12-34-27(20)21)26-23(30)10-18(36)11-24(26)31/h2-5,9-15,17,36H,6-8,32H2,1H3,(H,35,37)/t14-,15+,17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM376685 (N-{4-[(1R,3S,5S)-3-Amino-5-methylcyclohexyl]pyridi...) Show SMILES C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c2cc(cnc12)-c1c(F)cc(O)cc1F |r| Show InChI InChI=1S/C28H25F3N4O2/c1-14-6-15(8-17(32)7-14)19-4-5-33-13-25(19)35-28(37)20-2-3-22(29)21-9-16(12-34-27(20)21)26-23(30)10-18(36)11-24(26)31/h2-5,9-15,17,36H,6-8,32H2,1H3,(H,35,37)/t14-,15+,17-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University					Assay Description Pim-1 and Pim-3 kinase assays—20 μL reactions were run in white 384 well polystyrene plates dotted with 0.8 μL compound/DMSO in the assay b...				J Med Chem 50: 4928-38 (2007) BindingDB Entry DOI: 10.7270/Q20G3NF8
					More data for this Ligand-Target Pair

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