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Compile Data Set for Download or QSAR

Found 44 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50012735   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50098184
PNG
(AG-26 | CHEMBL1289260)
Show SMILES COc1ccc(CCNC(=O)Nc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C19H32N2O/c1-14(2)17-11-16(13-21-7-9-22-10-8-21)12-18(15(3)4)19(17)20(5)6/h11-12,14-15H,7-10,13H2,1-6H3
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Article
PubMed
n/an/an/an/a 990n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559843
PNG
(CHEMBL4749577)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2cc3ccccc3s2)c(F)c1 |r|
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n/an/an/an/a 0.760n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559804
PNG
(CHEMBL4760555)
Show SMILES COc1ccc(CC(CO)NC(=O)Nc2ccc(Cl)cc2)cc1
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n/an/an/an/a 6.80n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559805
PNG
(CHEMBL4765025)
Show SMILES COc1ccc(CC(NC(=O)Nc2ccc(Cl)cc2)C(O)=O)cc1
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n/an/an/an/a 31n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559806
PNG
(CHEMBL4796468)
Show SMILES COc1ccc(CC(NC(=O)Nc2ccc(Cl)cc2)C(N)=O)cc1
PDB

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n/an/an/an/a 3.60n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559807
PNG
(CHEMBL4778312)
Show SMILES COc1ccc(cc1)[C@@H]1NC(=O)[C@@H]1NC(=O)Nc1ccc(Cl)cc1 |r|
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n/an/an/an/a 12n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559808
PNG
(CHEMBL4756217)
Show SMILES COc1ccc(cc1)[C@@H]1NC(=O)[C@H]1NC(=O)Nc1ccc(Cl)cc1 |r|
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n/an/an/an/a>100n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559809
PNG
(CHEMBL4793814)
Show SMILES COc1ccc(cc1)[C@@H]1CNC(=O)[C@@H]1NC(=O)Nc1ccc(Cl)cc1 |r|
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n/an/an/an/a 0.910n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559810
PNG
(CHEMBL4744094)
Show SMILES COc1ccc(cc1)[C@@H]1CNC(=O)[C@H]1NC(=O)Nc1ccc(Cl)cc1 |r|
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n/an/an/an/a 0.180n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559811
PNG
(CHEMBL4784400)
Show SMILES COc1ccc(cc1)[C@@H]1CCNC(=O)[C@H]1NC(=O)Nc1ccc(Cl)cc1 |r|
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n/an/an/an/a 0.110n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559812
PNG
(CHEMBL4740375)
Show SMILES COc1ccc(cc1)C1CNC(=O)C1NC(=O)Nc1ccc(Cl)cc1
PDB

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n/an/an/an/a 4.60n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559812
PNG
(CHEMBL4740375)
Show SMILES COc1ccc(cc1)C1CNC(=O)C1NC(=O)Nc1ccc(Cl)cc1
PDB

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n/an/an/an/a 4.60n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559813
PNG
(CHEMBL4793603)
Show SMILES COc1ccc(cc1)[C@H]1CNC(=O)[C@@H]1NC(=O)Nc1ccc(Cl)cc1 |r|
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n/an/an/an/a 34n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559810
PNG
(CHEMBL4744094)
Show SMILES COc1ccc(cc1)[C@@H]1CNC(=O)[C@H]1NC(=O)Nc1ccc(Cl)cc1 |r|
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n/an/an/an/a 0.180n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559814
PNG
(CHEMBL4743917)
Show SMILES COc1ccc(cc1)[C@@H]1CNC(=O)[C@H]1NC(=O)Nc1ccc(F)cc1 |r|
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n/an/an/an/a 0.0850n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559815
PNG
(CHEMBL4745044)
Show SMILES COc1ccc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r|
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n/an/an/an/a 0.450n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559816
PNG
(CHEMBL4751168)
Show SMILES COc1ccc(cc1F)[C@@H]1CNC(=O)[C@H]1NC(=O)Nc1ccc(F)cc1 |r|
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n/an/an/an/a 0.900n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559817
PNG
(CHEMBL4743133)
Show SMILES COc1ccc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(Cl)c1 |r|
PDB

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n/an/an/an/a 4n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559818
PNG
(CHEMBL4743084)
Show SMILES COc1ccc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(C)c1 |r|
PDB

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n/an/an/an/a 1.60n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559819
PNG
(CHEMBL4793557)
Show SMILES Fc1ccc(NC(=O)N[C@H]2[C@@H](CNC2=O)c2ccc(Cl)cc2F)cc1 |r|
PDB

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n/an/an/an/a 3.10n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559820
PNG
(CHEMBL4744835)
Show SMILES COc1cc(F)c(cc1F)[C@@H]1CNC(=O)[C@H]1NC(=O)Nc1ccc(F)cc1 |r|
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n/an/an/an/a 0.150n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559821
PNG
(CHEMBL4781596)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r|
PDB

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n/an/an/an/a 0.140n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559822
PNG
(CHEMBL4753713)
Show SMILES COc1cnc([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r|
PDB

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n/an/an/an/a 0.360n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559823
PNG
(CHEMBL4756320)
Show SMILES CCOc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r|
PDB

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n/an/an/an/a 14n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559824
PNG
(CHEMBL4783963)
Show SMILES CCc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r|
PDB

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n/an/an/an/a 5.80n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559825
PNG
(CHEMBL4758129)
Show SMILES Fc1ccc(NC(=O)N[C@H]2[C@@H](CNC2=O)c2c(F)cc(cc2F)C#N)cc1 |r|
PDB

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n/an/an/an/a 9.70n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559826
PNG
(CHEMBL4781488)
Show SMILES CNc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 |r|
PDB

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n/an/an/an/a 1.40n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559827
PNG
(CHEMBL4763824)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2cccc(F)c2)c(F)c1 |r|
PDB

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antibodypedia
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n/an/an/an/a 0.950n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559828
PNG
(CHEMBL4797598)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2F)c(F)c1 |r|
PDB

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n/an/an/an/a 43n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559829
PNG
(CHEMBL4784510)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 |r|
PDB

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UniChem
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PubMed
n/an/an/an/a 0.410n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559830
PNG
(CHEMBL4758920)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)cc2)c(F)c1 |r|
PDB

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n/an/an/an/a 0.110n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559831
PNG
(CHEMBL4761554)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Br)cc2)c(F)c1 |r|
PDB

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n/an/an/an/a 0.190n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559832
PNG
(CHEMBL4742149)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(cc2)C#N)c(F)c1 |r|
PDB

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n/an/an/an/a 0.780n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559833
PNG
(CHEMBL4763673)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(C)cc2)c(F)c1 |r|
PDB

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n/an/an/an/a 2n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559834
PNG
(CHEMBL4789579)
Show SMILES COc1ccc(NC(=O)N[C@H]2[C@@H](CNC2=O)c2c(F)cc(OC)cc2F)cc1 |r|
PDB

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n/an/an/an/a 3.20n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559835
PNG
(CHEMBL4762030)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)c(F)c2)c(F)c1 |r|
PDB

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n/an/an/an/a 0.160n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559836
PNG
(CHEMBL4755590)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)c(O)c2)c(F)c1 |r|
PDB

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n/an/an/an/a 0.0870n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559837
PNG
(CHEMBL4776349)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)c(O)c2)c(F)c1 |r|
PDB

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n/an/an/an/a 0.0500n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559838
PNG
(CHEMBL4790836)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(C)c(O)c2)c(F)c1 |r|
PDB

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n/an/an/an/a 0.0780n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559839
PNG
(CHEMBL4792002)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)cn2)c(F)c1 |r|
PDB

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n/an/an/an/a 4.5n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559840
PNG
(CHEMBL4760897)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)s2)c(F)c1 |r|
PDB

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n/an/an/an/a 0.290n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559841
PNG
(CHEMBL4790245)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ncc(Cl)s2)c(F)c1 |r|
PDB

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n/an/an/an/a 1.90n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559842
PNG
(CHEMBL4778725)
Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2cc(C)ns2)c(F)c1 |r|
PDB

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n/an/an/an/a 0.320n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50559803
PNG
(CHEMBL4782531)
Show SMILES COc1ccc(CC(C)NC(=O)Nc2ccc(Cl)cc2)cc1
PDB

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n/an/an/an/a 23n/an/an/an/a


TBA

Assay Description
Agonist activity at human FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b02101
BindingDB Entry DOI: 10.7270/Q2V98CSC
More data for this
Ligand-Target Pair