Compile Data Set for Download or QSAR

Found 9 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Translocator protein (Homo sapiens (Human))	BDBM279583 (US10035780, Compound 7) Show SMILES CCN(CC)C(=O)Oc1nc(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C19H19N3O2/c1-3-22(4-2)19(23)24-18-15-12-8-9-13-16(15)20-17(21-18)14-10-6-5-7-11-14/h5-13H,3-4H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. US Patent					Assay Description For the assays described herein systemic injections of kainic in rats were applied and also contusion (Veenman et al. 2002; Soustiel et al. Neuropath...				US Patent US10035780 (2018) BindingDB Entry DOI: 10.7270/Q20V8FTD
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM279584 (US10035780, Compound 8) Show SMILES CCN(CC)C(=O)Oc1nc(nc2ccccc12)-c1ccccc1Cl Show InChI InChI=1S/C19H18ClN3O2/c1-3-23(4-2)19(24)25-18-14-10-6-8-12-16(14)21-17(22-18)13-9-5-7-11-15(13)20/h5-12H,3-4H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. US Patent					Assay Description For the assays described herein systemic injections of kainic in rats were applied and also contusion (Veenman et al. 2002; Soustiel et al. Neuropath...				US Patent US10035780 (2018) BindingDB Entry DOI: 10.7270/Q20V8FTD
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM279580 (US10035780, Compound 4) Show SMILES CCN(CC)C(=O)Oc1nc(nc2ccccc12)-c1ccc(Br)cc1 Show InChI InChI=1S/C19H18BrN3O2/c1-3-23(4-2)19(24)25-18-15-7-5-6-8-16(15)21-17(22-18)13-9-11-14(20)12-10-13/h5-12H,3-4H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. US Patent					Assay Description For the assays described herein systemic injections of kainic in rats were applied and also contusion (Veenman et al. 2002; Soustiel et al. Neuropath...				US Patent US10035780 (2018) BindingDB Entry DOI: 10.7270/Q20V8FTD
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM279577 (US10035780, Compound 1) Show SMILES CCN(C)C(=O)Oc1nc(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C18H17N3O2/c1-3-21(2)18(22)23-17-14-11-7-8-12-15(14)19-16(20-17)13-9-5-4-6-10-13/h4-12H,3H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. US Patent					Assay Description For the assays described herein systemic injections of kainic in rats were applied and also contusion (Veenman et al. 2002; Soustiel et al. Neuropath...				US Patent US10035780 (2018) BindingDB Entry DOI: 10.7270/Q20V8FTD
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM279582 (US10035780, Compound 6) Show SMILES CCN(C)C(=O)Oc1nc(nc2ccccc12)-c1ccccc1Cl Show InChI InChI=1S/C18H16ClN3O2/c1-3-22(2)18(23)24-17-13-9-5-7-11-15(13)20-16(21-17)12-8-4-6-10-14(12)19/h4-11H,3H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. US Patent					Assay Description For the assays described herein systemic injections of kainic in rats were applied and also contusion (Veenman et al. 2002; Soustiel et al. Neuropath...				US Patent US10035780 (2018) BindingDB Entry DOI: 10.7270/Q20V8FTD
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM279578 (US10035780, Compound 2) Show SMILES CCN(CC)C(=O)Oc1nc(nc2ccccc12)-c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C19H17ClFN3O2/c1-3-24(4-2)19(25)26-18-13-7-5-6-8-16(13)22-17(23-18)12-9-10-15(21)14(20)11-12/h5-11H,3-4H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. US Patent					Assay Description For the assays described herein systemic injections of kainic in rats were applied and also contusion (Veenman et al. 2002; Soustiel et al. Neuropath...				US Patent US10035780 (2018) BindingDB Entry DOI: 10.7270/Q20V8FTD
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM279581 (US10035780, Compound 5) Show SMILES CN(C)C(=O)Oc1nc(nc2ccccc12)-c1ccccc1Cl Show InChI InChI=1S/C17H14ClN3O2/c1-21(2)17(22)23-16-12-8-4-6-10-14(12)19-15(20-16)11-7-3-5-9-13(11)18/h3-10H,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. US Patent					Assay Description For the assays described herein systemic injections of kainic in rats were applied and also contusion (Veenman et al. 2002; Soustiel et al. Neuropath...				US Patent US10035780 (2018) BindingDB Entry DOI: 10.7270/Q20V8FTD
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM279585 (US10035780, Compound A) Show SMILES CN(C)C(=O)Oc1nc(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C17H15N3O2/c1-20(2)17(21)22-16-13-10-6-7-11-14(13)18-15(19-16)12-8-4-3-5-9-12/h3-11H,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. US Patent					Assay Description For the assays described herein systemic injections of kainic in rats were applied and also contusion (Veenman et al. 2002; Soustiel et al. Neuropath...				US Patent US10035780 (2018) BindingDB Entry DOI: 10.7270/Q20V8FTD
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM279579 (US10035780, Compound 3) Show SMILES CCN(CC)C(=O)Oc1nc(nc2ccccc12)-c1c(Cl)cccc1Cl Show InChI InChI=1S/C19H17Cl2N3O2/c1-3-24(4-2)19(25)26-18-12-8-5-6-11-15(12)22-17(23-18)16-13(20)9-7-10-14(16)21/h5-11H,3-4H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. US Patent					Assay Description For the assays described herein systemic injections of kainic in rats were applied and also contusion (Veenman et al. 2002; Soustiel et al. Neuropath...				US Patent US10035780 (2018) BindingDB Entry DOI: 10.7270/Q20V8FTD
					More data for this Ligand-Target Pair