Found 20 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 669 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM286099
(N-(5-(ethylsulfonyl)-5-azaspiro[2.4]heptan-7-yl)-N...)Show SMILES CCS(=O)(=O)N1CC(N(C)c2ncnc3[nH]ccc23)C2(CC2)C1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM286098
((R)-3-((7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)...)Show SMILES CN([C@H]1CN(CC11CC1)S(=O)(=O)c1cccc(c1)C#N)c1ncnc2[nH]ccc12 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM286095
((R)-3-(7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)a...)Show SMILES CN([C@H]1CN(CC11CC1)C(=O)CC#N)c1ncnc2[nH]ccc12 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM286098
((R)-3-((7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)...)Show SMILES CN([C@H]1CN(CC11CC1)S(=O)(=O)c1cccc(c1)C#N)c1ncnc2[nH]ccc12 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 24.7 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM286096
(3-(7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino...) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 29.3 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM286096
(3-(7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino...) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 40.4 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM286098
((R)-3-((7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)...)Show SMILES CN([C@H]1CN(CC11CC1)S(=O)(=O)c1cccc(c1)C#N)c1ncnc2[nH]ccc12 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 58.6 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM286098
((R)-3-((7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)...)Show SMILES CN([C@H]1CN(CC11CC1)S(=O)(=O)c1cccc(c1)C#N)c1ncnc2[nH]ccc12 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM286096
(3-(7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino...) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 148 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM286099
(N-(5-(ethylsulfonyl)-5-azaspiro[2.4]heptan-7-yl)-N...)Show SMILES CCS(=O)(=O)N1CC(N(C)c2ncnc3[nH]ccc23)C2(CC2)C1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 198 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM286095
((R)-3-(7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)a...)Show SMILES CN([C@H]1CN(CC11CC1)C(=O)CC#N)c1ncnc2[nH]ccc12 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 252 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM286095
((R)-3-(7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)a...)Show SMILES CN([C@H]1CN(CC11CC1)C(=O)CC#N)c1ncnc2[nH]ccc12 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 412 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM286099
(N-(5-(ethylsulfonyl)-5-azaspiro[2.4]heptan-7-yl)-N...)Show SMILES CCS(=O)(=O)N1CC(N(C)c2ncnc3[nH]ccc23)C2(CC2)C1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 422 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM286096
(3-(7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino...) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 694 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM286097
((S)-3-(7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)a...)Show SMILES CN([C@@H]1CN(CC11CC1)C(=O)CC#N)c1ncnc2[nH]ccc12 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 787 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human)) | BDBM286097
((S)-3-(7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)a...)Show SMILES CN([C@@H]1CN(CC11CC1)C(=O)CC#N)c1ncnc2[nH]ccc12 |r| | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM286097
((S)-3-(7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)a...)Show SMILES CN([C@@H]1CN(CC11CC1)C(=O)CC#N)c1ncnc2[nH]ccc12 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM286097
((S)-3-(7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)a...)Show SMILES CN([C@@H]1CN(CC11CC1)C(=O)CC#N)c1ncnc2[nH]ccc12 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM286099
(N-(5-(ethylsulfonyl)-5-azaspiro[2.4]heptan-7-yl)-N...)Show SMILES CCS(=O)(=O)N1CC(N(C)c2ncnc3[nH]ccc23)C2(CC2)C1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM286095
((R)-3-(7-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)a...)Show SMILES CN([C@H]1CN(CC11CC1)C(=O)CC#N)c1ncnc2[nH]ccc12 |r| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
YANG JI CHEMICAL CO., LTD.; HAN WHA PHARMA CO., LTD.
US Patent
| |
US Patent US10081635 (2018)
BindingDB Entry DOI: 10.7270/Q2R213D4 |
More data for this
Ligand-Target Pair | |
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