Compile Data Set for Download or QSAR

Found 114 hits Enz. Inhib. hit(s) with all data for assayid = 2 entry = 178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174777 (US10053462, 8 | US9102686, 8 | US9540388, 8) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4cscn4)n2C3)c1Cl |r,THB:9:11:17.26.27:13.15.14| Show InChI InChI=1S/C19H15ClF3N5OS/c20-15-11(4-2-5-12(15)19(21,22)23)18(29)28-10-3-1-6-14(28)17-26-25-16(27(17)7-10)13-8-30-9-24-13/h2,4-5,8-10,14H,1,3,6-7H2/t10-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.30	n/a	2.5	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174777 (US10053462, 8 | US9102686, 8 | US9540388, 8) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4cscn4)n2C3)c1Cl |r,THB:9:11:17.26.27:13.15.14| Show InChI InChI=1S/C19H15ClF3N5OS/c20-15-11(4-2-5-12(15)19(21,22)23)18(29)28-10-3-1-6-14(28)17-26-25-16(27(17)7-10)13-8-30-9-24-13/h2,4-5,8-10,14H,1,3,6-7H2/t10-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.30	n/a	9.70	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM203334 ((6r,10s)-11-[(2,3-dichloro-4-fluorophenyl)carbonyl...) Show SMILES Fc1ccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4ccccn4)n2C3)c(Cl)c1Cl |r,THB:5:7:13.23.24:9.10.11| Show InChI InChI=1S/C20H16Cl2FN5O/c21-16-12(7-8-13(23)17(16)22)20(29)28-11-4-3-6-15(28)19-26-25-18(27(19)10-11)14-5-1-2-9-24-14/h1-2,5,7-9,11,15H,3-4,6,10H2/t11-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.20	n/a	20	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM203334 ((6r,10s)-11-[(2,3-dichloro-4-fluorophenyl)carbonyl...) Show SMILES Fc1ccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4ccccn4)n2C3)c(Cl)c1Cl |r,THB:5:7:13.23.24:9.10.11| Show InChI InChI=1S/C20H16Cl2FN5O/c21-16-12(7-8-13(23)17(16)22)20(29)28-11-4-3-6-15(28)19-26-25-18(27(19)10-11)14-5-1-2-9-24-14/h1-2,5,7-9,11,15H,3-4,6,10H2/t11-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.20	n/a	25	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM203315 ((6r,10s)-11-{[2-chloro-3-(trifluoromethyl)phenyl]c...) Show SMILES Cc1ccnc(c1)-c1nnc2[C@H]3CCC[C@@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:19:18:10.17.16:14.13.12| Show InChI InChI=1S/C22H19ClF3N5O/c1-12-8-9-27-16(10-12)19-28-29-20-17-7-2-4-13(11-30(19)20)31(17)21(32)14-5-3-6-15(18(14)23)22(24,25)26/h3,5-6,8-10,13,17H,2,4,7,11H2,1H3/t13-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.10	n/a	7.40	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM203315 ((6r,10s)-11-{[2-chloro-3-(trifluoromethyl)phenyl]c...) Show SMILES Cc1ccnc(c1)-c1nnc2[C@H]3CCC[C@@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:19:18:10.17.16:14.13.12| Show InChI InChI=1S/C22H19ClF3N5O/c1-12-8-9-27-16(10-12)19-28-29-20-17-7-2-4-13(11-30(19)20)31(17)21(32)14-5-3-6-15(18(14)23)22(24,25)26/h3,5-6,8-10,13,17H,2,4,7,11H2,1H3/t13-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.10	n/a	17	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM203331 ((6r,10s)-11-{[2-chloro-4-fluoro-3-(trifluoromethyl...) Show SMILES Fc1ccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4ccccn4)n2C3)c(Cl)c1C(F)(F)F |r,THB:5:7:13.23.24:9.10.11| Show InChI InChI=1S/C21H16ClF4N5O/c22-17-12(7-8-13(23)16(17)21(24,25)26)20(32)31-11-4-3-6-15(31)19-29-28-18(30(19)10-11)14-5-1-2-9-27-14/h1-2,5,7-9,11,15H,3-4,6,10H2/t11-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.20	n/a	10	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174802 (US10053462, 33 | US9102686, 33 | US9540388, 32) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4ccccn4)n2C3)c1Cl |r,THB:9:11:17.27.28:13.14.15| Show InChI InChI=1S/C21H17ClF3N5O/c22-17-13(6-4-7-14(17)21(23,24)25)20(31)30-12-5-3-9-16(30)19-28-27-18(29(19)11-12)15-8-1-2-10-26-15/h1-2,4,6-8,10,12,16H,3,5,9,11H2/t12-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.20	n/a	11	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM203331 ((6r,10s)-11-{[2-chloro-4-fluoro-3-(trifluoromethyl...) Show SMILES Fc1ccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4ccccn4)n2C3)c(Cl)c1C(F)(F)F |r,THB:5:7:13.23.24:9.10.11| Show InChI InChI=1S/C21H16ClF4N5O/c22-17-12(7-8-13(23)16(17)21(24,25)26)20(32)31-11-4-3-6-15(31)19-29-28-18(30(19)10-11)14-5-1-2-9-27-14/h1-2,5,7-9,11,15H,3-4,6,10H2/t11-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.20	n/a	13	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174802 (US10053462, 33 | US9102686, 33 | US9540388, 32) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4ccccn4)n2C3)c1Cl |r,THB:9:11:17.27.28:13.14.15| Show InChI InChI=1S/C21H17ClF3N5O/c22-17-13(6-4-7-14(17)21(23,24)25)20(31)30-12-5-3-9-16(30)19-28-27-18(29(19)11-12)15-8-1-2-10-26-15/h1-2,4,6-8,10,12,16H,3,5,9,11H2/t12-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.20	n/a	13	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM203332 ((6r,10s)-11-{[2-methyl-3-(trifluoromethyl)phenyl]c...) Show SMILES Cc1c(cccc1C(F)(F)F)C(=O)N1[C@H]2CCC[C@@H]1c1nnc(-c3ccccn3)n1C2 |r,THB:11:13:19.29.30:15.16.17| Show InChI InChI=1S/C22H20F3N5O/c1-13-15(7-5-8-16(13)22(23,24)25)21(31)30-14-6-4-10-18(30)20-28-27-19(29(20)12-14)17-9-2-3-11-26-17/h2-3,5,7-9,11,14,18H,4,6,10,12H2,1H3/t14-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.20	n/a	14	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM203332 ((6r,10s)-11-{[2-methyl-3-(trifluoromethyl)phenyl]c...) Show SMILES Cc1c(cccc1C(F)(F)F)C(=O)N1[C@H]2CCC[C@@H]1c1nnc(-c3ccccn3)n1C2 |r,THB:11:13:19.29.30:15.16.17| Show InChI InChI=1S/C22H20F3N5O/c1-13-15(7-5-8-16(13)22(23,24)25)21(31)30-14-6-4-10-18(30)20-28-27-19(29(20)12-14)17-9-2-3-11-26-17/h2-3,5,7-9,11,14,18H,4,6,10,12H2,1H3/t14-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.20	n/a	726	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174781 (US10053462, 12 | US9102686, 12 | US9540388, 12) Show SMILES Fc1ccc(nc1)-c1nnc2[C@@H]3CCC[C@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:19:18:10.17.16:14.12.13| Show InChI InChI=1S/C21H16ClF4N5O/c22-17-13(4-2-5-14(17)21(24,25)26)20(32)31-12-3-1-6-16(31)19-29-28-18(30(19)10-12)15-8-7-11(23)9-27-15/h2,4-5,7-9,12,16H,1,3,6,10H2/t12-,16+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.40	n/a	13	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174781 (US10053462, 12 | US9102686, 12 | US9540388, 12) Show SMILES Fc1ccc(nc1)-c1nnc2[C@@H]3CCC[C@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:19:18:10.17.16:14.12.13| Show InChI InChI=1S/C21H16ClF4N5O/c22-17-13(4-2-5-14(17)21(24,25)26)20(32)31-12-3-1-6-16(31)19-29-28-18(30(19)10-12)15-8-7-11(23)9-27-15/h2,4-5,7-9,12,16H,1,3,6,10H2/t12-,16+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.40	n/a	37	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174795 (US10053462, 26 | US9102686, 26 | US9540388, 26) Show SMILES COc1ccnc(c1)-c1nnc2[C@H]3CCC[C@@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:20:19:11.18.17:15.13.14| Show InChI InChI=1S/C22H19ClF3N5O2/c1-33-13-8-9-27-16(10-13)19-28-29-20-17-7-2-4-12(11-30(19)20)31(17)21(32)14-5-3-6-15(18(14)23)22(24,25)26/h3,5-6,8-10,12,17H,2,4,7,11H2,1H3/t12-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	1.40	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174830 (US10053462, 61 | US9102686, 61 | US9540388, 61) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4cccs4)n2C3)c1Cl |r,THB:9:11:16.25.26:13.14| Show InChI InChI=1S/C19H14ClF3N4OS/c20-15-11(3-1-4-12(15)19(21,22)23)18(28)27-10-6-7-13(27)16-24-25-17(26(16)9-10)14-5-2-8-29-14/h1-5,8,10,13H,6-7,9H2/t10-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	2.60	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174818 (US10053462, 49 | US9102686, 49 | US9540388, 49) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4cscn4)n2C3)c1Cl |r,TLB:9:11:14.13:16.26.25| Show InChI InChI=1S/C18H13ClF3N5OS/c19-14-10(2-1-3-11(14)18(20,21)22)17(28)27-9-4-5-13(27)16-25-24-15(26(16)6-9)12-7-29-8-23-12/h1-3,7-9,13H,4-6H2/t9-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	5	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174772 (US10053462, 3 | US9102686, 3 | US9540388, 3) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@@H]3CCC[C@H]2c2nnc(-c4ncccn4)n2C3)c1Cl |r,THB:9:11:17.27.28:13.15.14| Show InChI InChI=1S/C20H16ClF3N6O/c21-15-12(5-2-6-13(15)20(22,23)24)19(31)30-11-4-1-7-14(30)17-27-28-18(29(17)10-11)16-25-8-3-9-26-16/h2-3,5-6,8-9,11,14H,1,4,7,10H2/t11-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	8.10	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174772 (US10053462, 3 | US9102686, 3 | US9540388, 3) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@@H]3CCC[C@H]2c2nnc(-c4ncccn4)n2C3)c1Cl |r,THB:9:11:17.27.28:13.15.14| Show InChI InChI=1S/C20H16ClF3N6O/c21-15-12(5-2-6-13(15)20(22,23)24)19(31)30-11-4-1-7-14(30)17-27-28-18(29(17)10-11)16-25-8-3-9-26-16/h2-3,5-6,8-9,11,14H,1,4,7,10H2/t11-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	9.60	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174795 (US10053462, 26 | US9102686, 26 | US9540388, 26) Show SMILES COc1ccnc(c1)-c1nnc2[C@H]3CCC[C@@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:20:19:11.18.17:15.13.14| Show InChI InChI=1S/C22H19ClF3N5O2/c1-33-13-8-9-27-16(10-13)19-28-29-20-17-7-2-4-12(11-30(19)20)31(17)21(32)14-5-3-6-15(18(14)23)22(24,25)26/h3,5-6,8-10,12,17H,2,4,7,11H2,1H3/t12-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	10	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174818 (US10053462, 49 | US9102686, 49 | US9540388, 49) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4cscn4)n2C3)c1Cl |r,TLB:9:11:14.13:16.26.25| Show InChI InChI=1S/C18H13ClF3N5OS/c19-14-10(2-1-3-11(14)18(20,21)22)17(28)27-9-4-5-13(27)16-25-24-15(26(16)6-9)12-7-29-8-23-12/h1-3,7-9,13H,4-6H2/t9-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	14	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174796 (US10053462, 27 | US9102686, 27 | US9540388, 27) Show SMILES COc1ccnc(c1)-c1nnc2[C@@H]3CCC[C@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:20:19:11.18.17:15.13.14| Show InChI InChI=1S/C22H19ClF3N5O2/c1-33-13-8-9-27-16(10-13)19-28-29-20-17-7-2-4-12(11-30(19)20)31(17)21(32)14-5-3-6-15(18(14)23)22(24,25)26/h3,5-6,8-10,12,17H,2,4,7,11H2,1H3/t12-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	1.54E+3	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174796 (US10053462, 27 | US9102686, 27 | US9540388, 27) Show SMILES COc1ccnc(c1)-c1nnc2[C@@H]3CCC[C@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:20:19:11.18.17:15.13.14| Show InChI InChI=1S/C22H19ClF3N5O2/c1-33-13-8-9-27-16(10-13)19-28-29-20-17-7-2-4-12(11-30(19)20)31(17)21(32)14-5-3-6-15(18(14)23)22(24,25)26/h3,5-6,8-10,12,17H,2,4,7,11H2,1H3/t12-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	1.91E+3	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174830 (US10053462, 61 | US9102686, 61 | US9540388, 61) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4cccs4)n2C3)c1Cl |r,THB:9:11:16.25.26:13.14| Show InChI InChI=1S/C19H14ClF3N4OS/c20-15-11(3-1-4-12(15)19(21,22)23)18(28)27-10-6-7-13(27)16-24-25-17(26(16)9-10)14-5-2-8-29-14/h1-5,8,10,13H,6-7,9H2/t10-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM203314 ((6r,10s)-11-{[2-chloro-3-(trifluoromethyl)phenyl]c...) Show SMILES Cc1nc(ccc1F)-c1nnc2[C@H]3CCC[C@@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:20:19:11.18.17:15.14.13| Show InChI InChI=1S/C22H18ClF4N5O/c1-11-15(24)8-9-16(28-11)19-29-30-20-17-7-2-4-12(10-31(19)20)32(17)21(33)13-5-3-6-14(18(13)23)22(25,26)27/h3,5-6,8-9,12,17H,2,4,7,10H2,1H3/t12-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.90	n/a	31	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM203314 ((6r,10s)-11-{[2-chloro-3-(trifluoromethyl)phenyl]c...) Show SMILES Cc1nc(ccc1F)-c1nnc2[C@H]3CCC[C@@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:20:19:11.18.17:15.14.13| Show InChI InChI=1S/C22H18ClF4N5O/c1-11-15(24)8-9-16(28-11)19-29-30-20-17-7-2-4-12(10-31(19)20)32(17)21(33)13-5-3-6-14(18(13)23)22(25,26)27/h3,5-6,8-9,12,17H,2,4,7,10H2,1H3/t12-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.90	n/a	41	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM203324 ((6r,10s)-11-{[3-chloro-2-(trifluoromethyl)pyridin-...) Show SMILES FC(F)(F)c1nccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4ccccn4)n2C3)c1Cl |r,THB:9:11:17.27.28:13.14.15| Show InChI InChI=1S/C20H16ClF3N6O/c21-15-12(7-9-26-16(15)20(22,23)24)19(31)30-11-4-3-6-14(30)18-28-27-17(29(18)10-11)13-5-1-2-8-25-13/h1-2,5,7-9,11,14H,3-4,6,10H2/t11-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	13	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM203324 ((6r,10s)-11-{[3-chloro-2-(trifluoromethyl)pyridin-...) Show SMILES FC(F)(F)c1nccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4ccccn4)n2C3)c1Cl |r,THB:9:11:17.27.28:13.14.15| Show InChI InChI=1S/C20H16ClF3N6O/c21-15-12(7-9-26-16(15)20(22,23)24)19(31)30-11-4-3-6-14(30)18-28-27-17(29(18)10-11)13-5-1-2-8-25-13/h1-2,5,7-9,11,14H,3-4,6,10H2/t11-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	30	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174792 (US10053462, 23 | US9102686, 23 | US9540388, 23) Show SMILES Cc1cccc(n1)-c1nnc2[C@H]3CCC[C@@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:19:18:10.17.16:14.12.13| Show InChI InChI=1S/C22H19ClF3N5O/c1-12-5-2-9-16(27-12)19-28-29-20-17-10-3-6-13(11-30(19)20)31(17)21(32)14-7-4-8-15(18(14)23)22(24,25)26/h2,4-5,7-9,13,17H,3,6,10-11H2,1H3/t13-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	n/a	40	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174792 (US10053462, 23 | US9102686, 23 | US9540388, 23) Show SMILES Cc1cccc(n1)-c1nnc2[C@H]3CCC[C@@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:19:18:10.17.16:14.12.13| Show InChI InChI=1S/C22H19ClF3N5O/c1-12-5-2-9-16(27-12)19-28-29-20-17-10-3-6-13(11-30(19)20)31(17)21(32)14-7-4-8-15(18(14)23)22(24,25)26/h2,4-5,7-9,13,17H,3,6,10-11H2,1H3/t13-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	n/a	56	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174793 (US10053462, 24 | US9102686, 24 | US9540388, 24) Show SMILES Cc1cccc(n1)-c1nnc2[C@@H]3CCC[C@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:19:18:10.17.16:14.12.13| Show InChI InChI=1S/C22H19ClF3N5O/c1-12-5-2-9-16(27-12)19-28-29-20-17-10-3-6-13(11-30(19)20)31(17)21(32)14-7-4-8-15(18(14)23)22(24,25)26/h2,4-5,7-9,13,17H,3,6,10-11H2,1H3/t13-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	n/a	3.70E+3	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174793 (US10053462, 24 | US9102686, 24 | US9540388, 24) Show SMILES Cc1cccc(n1)-c1nnc2[C@@H]3CCC[C@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:19:18:10.17.16:14.12.13| Show InChI InChI=1S/C22H19ClF3N5O/c1-12-5-2-9-16(27-12)19-28-29-20-17-10-3-6-13(11-30(19)20)31(17)21(32)14-7-4-8-15(18(14)23)22(24,25)26/h2,4-5,7-9,13,17H,3,6,10-11H2,1H3/t13-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM203318 ((6r,10s)-11-{[2-chloro-3-(trifluoromethyl)phenyl]c...) Show SMILES FC(F)(F)c1ccnc(c1)-c1nnc2[C@H]3CCC[C@@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:22:21:13.20.19:17.16.15| Show InChI InChI=1S/C22H16ClF6N5O/c23-17-13(4-2-5-14(17)22(27,28)29)20(35)34-12-3-1-6-16(34)19-32-31-18(33(19)10-12)15-9-11(7-8-30-15)21(24,25)26/h2,4-5,7-9,12,16H,1,3,6,10H2/t12-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.80	n/a	1.60	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM203318 ((6r,10s)-11-{[2-chloro-3-(trifluoromethyl)phenyl]c...) Show SMILES FC(F)(F)c1ccnc(c1)-c1nnc2[C@H]3CCC[C@@H](Cn12)N3C(=O)c1cccc(c1Cl)C(F)(F)F |r,THB:22:21:13.20.19:17.16.15| Show InChI InChI=1S/C22H16ClF6N5O/c23-17-13(4-2-5-14(17)22(27,28)29)20(35)34-12-3-1-6-16(34)19-32-31-18(33(19)10-12)15-9-11(7-8-30-15)21(24,25)26/h2,4-5,7-9,12,16H,1,3,6,10H2/t12-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.80	n/a	1.70	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM203333 ((6r,10s)-11-[(2,4-dichloro-3-fluorophenyl)carbonyl...) Show SMILES Fc1c(Cl)ccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4ccccn4)n2C3)c1Cl |r,THB:7:9:15.25.26:11.12.13| Show InChI InChI=1S/C20H16Cl2FN5O/c21-13-8-7-12(16(22)17(13)23)20(29)28-11-4-3-6-15(28)19-26-25-18(27(19)10-11)14-5-1-2-9-24-14/h1-2,5,7-9,11,15H,3-4,6,10H2/t11-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.80	n/a	18	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM203333 ((6r,10s)-11-[(2,4-dichloro-3-fluorophenyl)carbonyl...) Show SMILES Fc1c(Cl)ccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4ccccn4)n2C3)c1Cl |r,THB:7:9:15.25.26:11.12.13| Show InChI InChI=1S/C20H16Cl2FN5O/c21-13-8-7-12(16(22)17(13)23)20(29)28-11-4-3-6-15(28)19-26-25-18(27(19)10-11)14-5-1-2-9-24-14/h1-2,5,7-9,11,15H,3-4,6,10H2/t11-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.80	n/a	462	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM203323 ((6r,10s)-11-{[3-fluoro-2-(trifluoromethyl)pyridin-...) Show SMILES Fc1c(ccnc1C(F)(F)F)C(=O)N1[C@H]2CCC[C@@H]1c1nnc(-c3ccccn3)n1C2 |r,THB:11:13:19.29.30:15.16.17| Show InChI InChI=1S/C20H16F4N6O/c21-15-12(7-9-26-16(15)20(22,23)24)19(31)30-11-4-3-6-14(30)18-28-27-17(29(18)10-11)13-5-1-2-8-25-13/h1-2,5,7-9,11,14H,3-4,6,10H2/t11-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.20	n/a	21	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM203323 ((6r,10s)-11-{[3-fluoro-2-(trifluoromethyl)pyridin-...) Show SMILES Fc1c(ccnc1C(F)(F)F)C(=O)N1[C@H]2CCC[C@@H]1c1nnc(-c3ccccn3)n1C2 |r,THB:11:13:19.29.30:15.16.17| Show InChI InChI=1S/C20H16F4N6O/c21-15-12(7-9-26-16(15)20(22,23)24)19(31)30-11-4-3-6-14(30)18-28-27-17(29(18)10-11)13-5-1-2-8-25-13/h1-2,5,7-9,11,14H,3-4,6,10H2/t11-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.20	n/a	327	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174821 (US10053462, 52 | US9102686, 52 | US9540388, 52) Show SMILES Fc1ccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4cscn4)n2C3)c(Cl)c1C(F)(F)F |r,TLB:5:7:10.9:12.22.21| Show InChI InChI=1S/C18H12ClF4N5OS/c19-14-9(2-3-10(20)13(14)18(21,22)23)17(29)28-8-1-4-12(28)16-26-25-15(27(16)5-8)11-6-30-7-24-11/h2-3,6-8,12H,1,4-5H2/t8-,12+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.30	n/a	10	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174815 (US10053462, 46 | US9102686, 46 | US9540388, 46) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4ncccn4)n2C3)c1Cl |r,THB:9:11:16.26.27:14.13| Show InChI InChI=1S/C19H14ClF3N6O/c20-14-11(3-1-4-12(14)19(21,22)23)18(30)29-10-5-6-13(29)16-26-27-17(28(16)9-10)15-24-7-2-8-25-15/h1-4,7-8,10,13H,5-6,9H2/t10-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.30	n/a	15	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174816 (US10053462, 47 | US9102686, 47 | US9540388, 47) Show SMILES Fc1ccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4cnccn4)n2C3)c(Cl)c1Cl |r,THB:5:7:12.22.23:10.9| Show InChI InChI=1S/C18H13Cl2FN6O/c19-14-10(2-3-11(21)15(14)20)18(28)27-9-1-4-13(27)17-25-24-16(26(17)8-9)12-7-22-5-6-23-12/h2-3,5-7,9,13H,1,4,8H2/t9-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.30	n/a	20	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174831 (US10053462, 62 | US9102686, 62 | US9540388, 62) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4ccc[nH]4)n2C3)c1Cl |r,THB:9:11:16.25.26:13.14| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.30	n/a	20	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174821 (US10053462, 52 | US9102686, 52 | US9540388, 52) Show SMILES Fc1ccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4cscn4)n2C3)c(Cl)c1C(F)(F)F |r,TLB:5:7:10.9:12.22.21| Show InChI InChI=1S/C18H12ClF4N5OS/c19-14-9(2-3-10(20)13(14)18(21,22)23)17(29)28-8-1-4-12(28)16-26-25-15(27(16)5-8)11-6-30-7-24-11/h2-3,6-8,12H,1,4-5H2/t8-,12+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.30	n/a	131	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174815 (US10053462, 46 | US9102686, 46 | US9540388, 46) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4ncccn4)n2C3)c1Cl |r,THB:9:11:16.26.27:14.13| Show InChI InChI=1S/C19H14ClF3N6O/c20-14-11(3-1-4-12(14)19(21,22)23)18(30)29-10-5-6-13(29)16-26-27-17(28(16)9-10)15-24-7-2-8-25-15/h1-4,7-8,10,13H,5-6,9H2/t10-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.30	n/a	253	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174802 (US10053462, 33 | US9102686, 33 | US9540388, 32) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4ccccn4)n2C3)c1Cl |r,THB:9:11:17.27.28:13.14.15| Show InChI InChI=1S/C21H17ClF3N5O/c22-17-13(6-4-7-14(17)21(23,24)25)20(31)30-12-5-3-9-16(30)19-28-27-18(29(19)11-12)15-8-1-2-10-26-15/h1-2,4,6-8,10,12,16H,3,5,9,11H2/t12-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.30	n/a	1.51E+3	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174816 (US10053462, 47 | US9102686, 47 | US9540388, 47) Show SMILES Fc1ccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4cnccn4)n2C3)c(Cl)c1Cl |r,THB:5:7:12.22.23:10.9| Show InChI InChI=1S/C18H13Cl2FN6O/c19-14-10(2-3-11(21)15(14)20)18(28)27-9-1-4-13(27)17-25-24-16(26(17)8-9)12-7-22-5-6-23-12/h2-3,5-7,9,13H,1,4,8H2/t9-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.30	n/a	1.92E+3	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174802 (US10053462, 33 | US9102686, 33 | US9540388, 32) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CCC[C@@H]2c2nnc(-c4ccccn4)n2C3)c1Cl |r,THB:9:11:17.27.28:13.14.15| Show InChI InChI=1S/C21H17ClF3N5O/c22-17-13(6-4-7-14(17)21(23,24)25)20(31)30-12-5-3-9-16(30)19-28-27-18(29(19)11-12)15-8-1-2-10-26-15/h1-2,4,6-8,10,12,16H,3,5,9,11H2/t12-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.30	n/a	2.11E+3	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM174831 (US10053462, 62 | US9102686, 62 | US9540388, 62) Show SMILES FC(F)(F)c1cccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4ccc[nH]4)n2C3)c1Cl |r,THB:9:11:16.25.26:13.14| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.30	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174822 (US10053462, 53 | US9102686, 53 | US9540388, 53) Show SMILES Cc1c(cccc1C(F)(F)F)C(=O)N1[C@H]2CC[C@@H]1c1nnc(-c3cscn3)n1C2 |r,TLB:11:13:16.15:18.28.27| Show InChI InChI=1S/C19H16F3N5OS/c1-10-12(3-2-4-13(10)19(20,21)22)18(28)27-11-5-6-15(27)17-25-24-16(26(17)7-11)14-8-29-9-23-14/h2-4,8-9,11,15H,5-7H2,1H3/t11-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.90	n/a	3.10	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM174823 (US10053462, 54 | US9102686, 54 | US9540388, 54) Show SMILES Fc1c(Cl)ccc(C(=O)N2[C@H]3CC[C@@H]2c2nnc(-c4cscn4)n2C3)c1Cl |r,TLB:7:9:12.11:14.24.23| Show InChI InChI=1S/C17H12Cl2FN5OS/c18-10-3-2-9(13(19)14(10)20)17(26)25-8-1-4-12(25)16-23-22-15(24(16)5-8)11-6-27-7-21-11/h2-3,6-8,12H,1,4-5H2/t8-,12+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.90	n/a	6.10	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description 1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...				US Patent US9540388 (2017) BindingDB Entry DOI: 10.7270/Q20V8B0D
					More data for this Ligand-Target Pair

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