Compile Data Set for Download or QSAR

Found 37 hits Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50017130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177834 (2-Methoxy-5-{[6-methoxy-7-(3-pyrrolidin-1-ylpropox...) Show SMILES COC1=CC(=O)C(Nc2ncnc3cc(OCCCN4CCCC4)c(OC)cc23)=CC1=O |c:31,t:2| Show InChI InChI=1S/C23H26N4O5/c1-30-20-13-18(28)17(11-19(20)29)26-23-15-10-21(31-2)22(12-16(15)24-14-25-23)32-9-5-8-27-6-3-4-7-27/h10-14H,3-9H2,1-2H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177834 (2-Methoxy-5-{[6-methoxy-7-(3-pyrrolidin-1-ylpropox...) Show SMILES COC1=CC(=O)C(Nc2ncnc3cc(OCCCN4CCCC4)c(OC)cc23)=CC1=O |c:31,t:2| Show InChI InChI=1S/C23H26N4O5/c1-30-20-13-18(28)17(11-19(20)29)26-23-15-10-21(31-2)22(12-16(15)24-14-25-23)32-9-5-8-27-6-3-4-7-27/h10-14H,3-9H2,1-2H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177847 (2-Methoxy-5-({6-methoxy-7-[(1-methylpiperidin-4-yl...) Show SMILES COC1=CC(=O)C(Nc2ncnc3cc(OCC4CCN(C)CC4)c(OC)cc23)=CC1=O |c:31,t:2| Show InChI InChI=1S/C23H26N4O5/c1-27-6-4-14(5-7-27)12-32-22-10-16-15(8-21(22)31-3)23(25-13-24-16)26-17-9-19(29)20(30-2)11-18(17)28/h8-11,13-14H,4-7,12H2,1-3H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM4851 ((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...) Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1 Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<15	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177825 (2-{[6-Methoxy-7-(2-methoxyethoxy)-4-quinazolinyl]a...) Show SMILES COCCOc1cc2ncnc(N=C3CC(=O)C(C)=CC3=O)c2cc1OC |w:12.11,c:18| Show InChI InChI=1S/C19H19N3O5/c1-11-6-16(24)14(8-15(11)23)22-19-12-7-17(26-3)18(27-5-4-25-2)9-13(12)20-10-21-19/h6-7,9-10H,4-5,8H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<15	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM21 (CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...) Show SMILES COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1 Show InChI InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	<15	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177841 (2-methoxy-5-{[6-methoxy-7-(2-methoxyethoxy)quinazo...) Show SMILES COCCOc1cc2ncnc(N=C3CC(=O)C(OC)=CC3=O)c2cc1OC |w:12.11,c:19| Show InChI InChI=1S/C19H19N3O6/c1-25-4-5-28-18-8-12-11(6-17(18)27-3)19(21-10-20-12)22-13-7-15(24)16(26-2)9-14(13)23/h6,8-10H,4-5,7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002581 (CHEMBL2113167) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(=CC3=O)N(C)C)c2cc1OC |c:17,t:13| Show InChI InChI=1S/C20H22N4O5/c1-24(2)15-10-16(25)14(8-17(15)26)23-20-12-7-18(28-4)19(29-6-5-27-3)9-13(12)21-11-22-20/h7-11H,5-6H2,1-4H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177798 (2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...) Show SMILES COCCOc1cc2ncnc(N=C3CC(=O)C(SC)=CC3=O)c2cc1OC |w:12.11,c:19| Show InChI InChI=1S/C19H19N3O5S/c1-25-4-5-27-17-8-12-11(6-16(17)26-2)19(21-10-20-12)22-13-7-15(24)18(28-3)9-14(13)23/h6,8-10H,4-5,7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177850 (2-[3-(Ethylamino)phenoxy]-5-{[6-methoxy-7-(2-metho...) Show SMILES CCNc1cccc(OC2=CC(=O)C(Nc3ncnc4cc(OCCOC)c(OC)cc34)=CC2=O)c1 |c:33,t:9| Show InChI InChI=1S/C26H26N4O6/c1-4-27-16-6-5-7-17(10-16)36-23-14-21(31)20(12-22(23)32)30-26-18-11-24(34-3)25(35-9-8-33-2)13-19(18)28-15-29-26/h5-7,10-15,27H,4,8-9H2,1-3H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002439 (CHEMBL2113174) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(Oc4ccccc4)=CC3=O)c2cc1OC |c:25,t:13| Show InChI InChI=1S/C24H21N3O6/c1-30-8-9-32-23-12-17-16(10-22(23)31-2)24(26-14-25-17)27-18-11-20(29)21(13-19(18)28)33-15-6-4-3-5-7-15/h3-7,10-14H,8-9H2,1-2H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177803 (2-[2-Fluoro-1-(fluoromethyl)ethoxy]-5-({6-methoxy-...) Show SMILES COc1cc2c(N=C3CC(=O)C(OC(CF)CF)=CC3=O)ncnc2cc1OCC1CCN(C)CC1 |w:6.5,c:17| Show InChI InChI=1S/C25H28F2N4O5/c1-31-5-3-15(4-6-31)13-35-24-9-18-17(7-23(24)34-2)25(29-14-28-18)30-19-8-21(33)22(10-20(19)32)36-16(11-26)12-27/h7,9-10,14-16H,3-6,8,11-13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002441 (CHEMBL2113176) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(OCc4cccnc4)=CC3=O)c2cc1OC |c:26,t:13| Show InChI InChI=1S/C24H22N4O6/c1-31-6-7-33-23-10-17-16(8-22(23)32-2)24(27-14-26-17)28-18-9-20(30)21(11-19(18)29)34-13-15-4-3-5-25-12-15/h3-5,8-12,14H,6-7,13H2,1-2H3,(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	193	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177826 (2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...) Show SMILES COCCOc1cc2ncnc(N=C3CC(=O)C(=CC3=O)N3CC3C)c2cc1OC |w:12.11,c:17| Show InChI InChI=1S/C21H22N4O5/c1-12-10-25(12)16-9-17(26)15(7-18(16)27)24-21-13-6-19(29-3)20(30-5-4-28-2)8-14(13)22-11-23-21/h6,8-9,11-12H,4-5,7,10H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	206	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002440 (CHEMBL2113175) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(OC(CF)CF)=CC3=O)c2cc1OC |c:23,t:13| Show InChI InChI=1S/C21H21F2N3O6/c1-29-3-4-31-20-7-14-13(5-19(20)30-2)21(25-11-24-14)26-15-6-17(28)18(8-16(15)27)32-12(9-22)10-23/h5-8,11-12H,3-4,9-10H2,1-2H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	212	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002591 (CHEMBL2113180) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(=CC3=O)N3CCCCC3)c2cc1OC |c:17,t:13| Show InChI InChI=1S/C23H26N4O5/c1-30-8-9-32-22-12-16-15(10-21(22)31-2)23(25-14-24-16)26-17-11-20(29)18(13-19(17)28)27-6-4-3-5-7-27/h10-14H,3-9H2,1-2H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002594 (CHEMBL2113186) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(Oc4ccc(cc4)-n4ccnc4)=CC3=O)c2cc1OC |c:31,t:13| Show InChI InChI=1S/C27H23N5O6/c1-35-9-10-37-26-13-20-19(11-25(26)36-2)27(30-15-29-20)31-21-12-23(34)24(14-22(21)33)38-18-5-3-17(4-6-18)32-8-7-28-16-32/h3-8,11-16H,9-10H2,1-2H3,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002587 (CHEMBL2113184) Show SMILES COc1cc2c(NC3=CC(=O)C(OCCN(C)c4ccccc4)=CC3=O)ncnc2cc1OCC1CCN(C)CC1 |c:23,t:7| Show InChI InChI=1S/C31H35N5O5/c1-35-11-9-21(10-12-35)19-41-30-17-24-23(15-29(30)39-3)31(33-20-32-24)34-25-16-27(38)28(18-26(25)37)40-14-13-36(2)22-7-5-4-6-8-22/h4-8,15-18,20-21H,9-14,19H2,1-3H3,(H,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	329	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177798 (2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...) Show SMILES COCCOc1cc2ncnc(N=C3CC(=O)C(SC)=CC3=O)c2cc1OC |w:12.11,c:19| Show InChI InChI=1S/C19H19N3O5S/c1-25-4-5-27-17-8-12-11(6-16(17)26-2)19(21-10-20-12)22-13-7-15(24)18(28-3)9-14(13)23/h6,8-10H,4-5,7H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	456	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002446 (CHEMBL2113172) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(OC)=C(Cl)C3=O)c2cc1OC |t:13,19| Show InChI InChI=1S/C19H18ClN3O6/c1-26-4-5-29-15-8-11-10(6-14(15)27-2)19(22-9-21-11)23-12-7-13(24)18(28-3)16(20)17(12)25/h6-9H,4-5H2,1-3H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	466	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002443 (CHEMBL2113169) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(OC(C)C)=CC3=O)c2cc1OC |c:21,t:13| Show InChI InChI=1S/C21H23N3O6/c1-12(2)30-18-10-16(25)15(8-17(18)26)24-21-13-7-19(28-4)20(29-6-5-27-3)9-14(13)22-11-23-21/h7-12H,5-6H2,1-4H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002445 (CHEMBL2113171) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(OC(CF)CF)=C(Cl)C3=O)c2cc1OC |t:13,23| Show InChI InChI=1S/C21H20ClF2N3O6/c1-30-3-4-32-17-7-13-12(5-16(17)31-2)21(26-10-25-13)27-14-6-15(28)20(18(22)19(14)29)33-11(8-23)9-24/h5-7,10-11H,3-4,8-9H2,1-2H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	792	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177833 (2-(2,2-Difluoroethoxy)-5-{[6-methoxy-7-(2-methoxye...) Show SMILES COCCOc1cc2ncnc(N=C3CC(=O)C(OCC(F)F)=CC3=O)c2cc1OC |w:12.11,c:22| Show InChI InChI=1S/C20H19F2N3O6/c1-28-3-4-30-18-7-12-11(5-17(18)29-2)20(24-10-23-12)25-13-6-15(27)16(8-14(13)26)31-9-19(21)22/h5,7-8,10,19H,3-4,6,9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177813 (2-(4-Ethylpiperazin-1-yl)-5-{[6-methoxy-7-(2-metho...) Show SMILES CCN1CCN(CC1)C1=CC(=O)C(Nc2ncnc3cc(OCCOC)c(OC)cc23)=CC1=O |c:33,t:9| Show InChI InChI=1S/C24H29N5O5/c1-4-28-5-7-29(8-6-28)19-14-20(30)18(12-21(19)31)27-24-16-11-22(33-3)23(34-10-9-32-2)13-17(16)25-15-26-24/h11-15H,4-10H2,1-3H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002442 (CHEMBL2113178) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C=CC3=O)c2cc1OC |c:17,t:13| Show InChI InChI=1S/C18H17N3O5/c1-24-5-6-26-17-9-13-12(8-16(17)25-2)18(20-10-19-13)21-14-7-11(22)3-4-15(14)23/h3-4,7-10H,5-6H2,1-2H3,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177811 (2-{[-6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]...) Show SMILES COCCOc1cc2ncnc(N=C3CC(=O)C(=CC3=O)N3CC(C)OC3=O)c2cc1OC |w:12.11,c:17| Show InChI InChI=1S/C22H22N4O7/c1-12-10-26(22(29)33-12)16-9-17(27)15(7-18(16)28)25-21-13-6-19(31-3)20(32-5-4-30-2)8-14(13)23-11-24-21/h6,8-9,11-12H,4-5,7,10H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177836 (2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...) Show SMILES COCCOc1cc2ncnc(N=C3CC(=O)C(OCCOc4ccccc4)=CC3=O)c2cc1OC |w:12.11,c:28| Show InChI InChI=1S/C26H25N3O7/c1-32-8-9-36-25-14-19-18(12-24(25)33-2)26(28-16-27-19)29-20-13-22(31)23(15-21(20)30)35-11-10-34-17-6-4-3-5-7-17/h3-7,12,14-16H,8-11,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002444 (CHEMBL2113170) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(=CC3=O)N3CCN(Cc4ccccc4)CC3)c2cc1OC |c:17,t:13| Show InChI InChI=1S/C29H31N5O5/c1-37-12-13-39-28-16-22-21(14-27(28)38-2)29(31-19-30-22)32-23-15-26(36)24(17-25(23)35)34-10-8-33(9-11-34)18-20-6-4-3-5-7-20/h3-7,14-17,19H,8-13,18H2,1-2H3,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177802 (2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...) Show SMILES COCCOc1cc2ncnc(N=C3CC(=O)C(=CC3=O)N(C)c3ccccc3)c2cc1OC |w:12.11,c:17| Show InChI InChI=1S/C25H24N4O5/c1-29(16-7-5-4-6-8-16)20-14-21(30)19(12-22(20)31)28-25-17-11-23(33-3)24(34-10-9-32-2)13-18(17)26-15-27-25/h4-8,11,13-15H,9-10,12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177837 (2-Ethoxy-5-{[6-methoxy-7-(2-methoxyethoxy)quinazol...) Show SMILES CCOC1=CC(=O)C(Nc2ncnc3cc(OCCOC)c(OC)cc23)=CC1=O |c:27,t:3| Show InChI InChI=1S/C20H21N3O6/c1-4-28-17-10-15(24)14(8-16(17)25)23-20-12-7-18(27-3)19(29-6-5-26-2)9-13(12)21-11-22-20/h7-11H,4-6H2,1-3H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177837 (2-Ethoxy-5-{[6-methoxy-7-(2-methoxyethoxy)quinazol...) Show SMILES CCOC1=CC(=O)C(Nc2ncnc3cc(OCCOC)c(OC)cc23)=CC1=O |c:27,t:3| Show InChI InChI=1S/C20H21N3O6/c1-4-28-17-10-15(24)14(8-16(17)25)23-20-12-7-18(27-3)19(29-6-5-26-2)9-13(12)21-11-22-20/h7-11H,4-6H2,1-3H3,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177802 (2-{[6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yl]a...) Show SMILES COCCOc1cc2ncnc(N=C3CC(=O)C(=CC3=O)N(C)c3ccccc3)c2cc1OC |w:12.11,c:17| Show InChI InChI=1S/C25H24N4O5/c1-29(16-7-5-4-6-8-16)20-14-21(30)19(12-22(20)31)28-25-17-11-23(33-3)24(34-10-9-32-2)13-18(17)26-15-27-25/h4-8,11,13-15H,9-10,12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50177852 (3-Chloro-2-ethoxy-5-{[6-methoxy-7-(2-methoxyethoxy...) Show SMILES CCOC1=C(Cl)C(=O)C(Nc2ncnc3cc(OCCOC)c(OC)cc23)=CC1=O |c:3,28| Show InChI InChI=1S/C20H20ClN3O6/c1-4-29-19-14(25)8-13(18(26)17(19)21)24-20-11-7-15(28-3)16(30-6-5-27-2)9-12(11)22-10-23-20/h7-10H,4-6H2,1-3H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002449 (CHEMBL2113166) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(Cl)=CC3=O)c2cc1OC |c:18,t:13| Show InChI InChI=1S/C18H16ClN3O5/c1-25-3-4-27-17-8-12-10(5-16(17)26-2)18(21-9-20-12)22-13-7-14(23)11(19)6-15(13)24/h5-9H,3-4H2,1-2H3,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002582 (CHEMBL2113168) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(=CC3=O)N3CCOCC3)c2cc1OC |c:17,t:13| Show InChI InChI=1S/C22H24N4O6/c1-29-7-8-32-21-11-15-14(9-20(21)30-2)22(24-13-23-15)25-16-10-19(28)17(12-18(16)27)26-3-5-31-6-4-26/h9-13H,3-8H2,1-2H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002592 (CHEMBL2113188) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(OC(c4ccccc4)C(F)(F)F)=CC3=O)c2cc1OC |c:30,t:13| Show InChI InChI=1S/C26H22F3N3O6/c1-35-8-9-37-23-12-17-16(10-22(23)36-2)25(31-14-30-17)32-18-11-20(34)21(13-19(18)33)38-24(26(27,28)29)15-6-4-3-5-7-15/h3-7,10-14,24H,8-9H2,1-2H3,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50002590 (CHEMBL2113182) Show SMILES COCCOc1cc2ncnc(NC3=CC(=O)C(OCc4ccc(F)cc4)=CC3=O)c2cc1OC |c:27,t:13| Show InChI InChI=1S/C25H22FN3O6/c1-32-7-8-34-24-11-18-17(9-23(24)33-2)25(28-14-27-18)29-19-10-21(31)22(12-20(19)30)35-13-15-3-5-16(26)6-4-15/h3-6,9-12,14H,7-8,13H2,1-2H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory activity against VEGF stimulated autophosphorylation of VEGFR2 expressed in KDR15 cells				J Med Chem 48: 7560-81 (2005) Article DOI: 10.1021/jm050559f BindingDB Entry DOI: 10.7270/Q2028R3S
					More data for this Ligand-Target Pair