BindingDB PrimarySearch

Found 957 hits of ic50 data for polymerid = 6311
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50612011 (CHEMBL5288122) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50612010 (CHEMBL5271462) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50267086 (Adociaquinone B \| CHEMBL476648) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris Descartes Curated by ChEMBL					Assay Description Inhibition of human recombinant CDC25B				Bioorg Med Chem 16: 9040-9 (2008) Article DOI: 10.1016/j.bmc.2008.08.009 BindingDB Entry DOI: 10.7270/Q2833SZB
Universit£ Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50267086 (Adociaquinone B \| CHEMBL476648) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Inhibition of Cdc25B				J Med Chem 55: 4142-58 (2012) Article DOI: 10.1021/jm201624h BindingDB Entry DOI: 10.7270/Q2X34ZJ9
Universit£ di Napoli Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50267086 (Adociaquinone B \| CHEMBL476648) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Polytechnic Institute and State University Curated by ChEMBL					Assay Description Inhibition of histidine-tagged full length human Cdc25B expressed in Escherichia coli				Bioorg Med Chem 17: 2276-81 (2009) Article DOI: 10.1016/j.bmc.2008.10.090 BindingDB Entry DOI: 10.7270/Q21J99MN
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM41999 (3-(3,4,5-trihydroxy-6-keto-xanthen-9-yl)propionic ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant phosphatase activity of Cdc25B catalytic domain expressed in Escherichia coli BL21(DE3) using OMFP as substrate by spectrof...				J Med Chem 55: 4142-58 (2012) Article DOI: 10.1021/jm201624h BindingDB Entry DOI: 10.7270/Q2X34ZJ9
Universit£ di Napoli Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50208827 (2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione \|...) Show SMILES OCCSC1=C(SCCO)C(=O)c2ccccc2C1=O \|c:4\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sejong University Curated by ChEMBL					Assay Description Inhibition of GST tagged Cdc25B				Bioorg Med Chem Lett 17: 2351-4 (2007) Article DOI: 10.1016/j.bmcl.2006.12.046 BindingDB Entry DOI: 10.7270/Q2DF6QWF
Sejong University Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50267086 (Adociaquinone B \| CHEMBL476648) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Polytechnic Institute and State University Curated by ChEMBL					Assay Description Inhibition of histidine-tagged human recombinant Cdc25B catalytic domain expressed in Escherichia coli				Bioorg Med Chem 17: 2276-81 (2009) Article DOI: 10.1016/j.bmc.2008.10.090 BindingDB Entry DOI: 10.7270/Q21J99MN
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317356 (3-(3-stearoyl-1H-pyrazole-5-carboxamido)thiophene-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50177318 (2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibitory activity against cdc25B phosphatase				Bioorg Med Chem Lett 16: 499-502 (2005) Article DOI: 10.1016/j.bmcl.2005.10.062 BindingDB Entry DOI: 10.7270/Q2319VFG
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50208827 (2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione \|...) Show SMILES OCCSC1=C(SCCO)C(=O)c2ccccc2C1=O \|c:4\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
Max-Planck-Institute of Molecular Physiology Curated by ChEMBL					Assay Description Inhibition of human Cdc25B				Bioorg Med Chem 19: 2145-55 (2011) Article DOI: 10.1016/j.bmc.2011.02.047 BindingDB Entry DOI: 10.7270/Q2BR8SHK
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317355 (2-(3-stearoyl-1H-pyrazole-5-carboxamido)benzoic ac...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317365 (5-(4-chlorophenyl)-3-stearoylpyrrolo[3,4-c]pyrazol...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM124256 ((3S,3aR,4S,7aS)-4-acetyl-7-dodecyl-3-methyl-1-oxo-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Lanzhou University									Org Biomol Chem 12: 3441-5 (2014) Article DOI: 10.1039/c4ob00214h BindingDB Entry DOI: 10.7270/Q2JQ0ZPC
Lanzhou University					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50297586 (CHEMBL557129 \| N-(1-benzyl-3-cyano-1H-pyrrolo[3,2-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Sejong University Curated by ChEMBL					Assay Description Inhibition of GST-fused Cdc25B				Bioorg Med Chem Lett 19: 4372-5 (2009) Article DOI: 10.1016/j.bmcl.2009.05.078 BindingDB Entry DOI: 10.7270/Q2D79BGK
Sejong University Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 \| Sodium orthovanadate (SOV) \| Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...				Eur J Med Chem 172: 163-173 (2019) Article DOI: 10.1016/j.ejmech.2019.03.059 BindingDB Entry DOI: 10.7270/Q2028VWB
Yanbian University College of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50106497 (6-Chloro-7-(2-morpholin-4-yl-ethylamino)-quinoline...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human cell division cycle 25B				J Med Chem 44: 4042-9 (2001) BindingDB Entry DOI: 10.7270/Q2X34WR5
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50297585 (CHEMBL557673 \| N-(1-benzyl-1H-pyrrolo[3,2-b]quinox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Sejong University Curated by ChEMBL					Assay Description Inhibition of GST-fused Cdc25B				Bioorg Med Chem Lett 19: 4372-5 (2009) Article DOI: 10.1016/j.bmcl.2009.05.078 BindingDB Entry DOI: 10.7270/Q2D79BGK
Sejong University Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM124255 ((3S,3aR,4S,7R,7aS)-4-acetyl-7-dodecyl-3-methyl-1-o...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Lanzhou University									Org Biomol Chem 12: 3441-5 (2014) Article DOI: 10.1039/c4ob00214h BindingDB Entry DOI: 10.7270/Q2JQ0ZPC
Lanzhou University					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM31040 (1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...) Show SMILES CCn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	223	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The Cdc25B Phosphatase Secondary Selectivity Assay has been developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) part...				PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2FF3QRT
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317352 (5-phenyl-3-stearoylpyrrolo[3,4-c]pyrazole-4,6(1H,5...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317364 (5-(3-chlorophenyl)-3-stearoylpyrrolo[3,4-c]pyrazol...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317366 (5-(2-bromophenyl)-3-stearoylpyrrolo[3,4-c]pyrazole...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50504361 (CHEMBL4452484) Show SMILES CSC1=C(SC)C(=O)c2ccccc2C1=O \|c:2\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University Curated by ChEMBL					Assay Description Inhibition of recombinant Cdc25B (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assay				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111719 BindingDB Entry DOI: 10.7270/Q2D221X9
Montana State University Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50504361 (CHEMBL4452484) Show SMILES CSC1=C(SC)C(=O)c2ccccc2C1=O \|c:2\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50341995 (5-(2-(dimethylamino)ethylamino)-2,6-dimethylbenzo[...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Max-Planck-Institute of Molecular Physiology Curated by ChEMBL					Assay Description Inhibition of human Cdc25B				Bioorg Med Chem 19: 2145-55 (2011) Article DOI: 10.1016/j.bmc.2011.02.047 BindingDB Entry DOI: 10.7270/Q2BR8SHK
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50099736 (4-Ethoxy-[1,2]naphthoquinone \| 4-ethoxynaphthalene...) Show SMILES CCOC1=CC(=O)C(=O)c2ccccc12 \|t:3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Polytechnic Institute and State University Curated by ChEMBL					Assay Description Inhibition of histidine-tagged human recombinant Cdc25B catalytic domain expressed in Escherichia coli				Bioorg Med Chem 17: 2276-81 (2009) Article DOI: 10.1016/j.bmc.2008.10.090 BindingDB Entry DOI: 10.7270/Q21J99MN
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50106505 (6-Chloro-7-(indan-1-ylamino)-quinoline-5,8-dione \|...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human cell division cycle 25B				J Med Chem 44: 4042-9 (2001) BindingDB Entry DOI: 10.7270/Q2X34WR5
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317382 (5-(naphthalen-1-yl)-3-stearoylpyrrolo[3,4-c]pyrazo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317376 (3-stearoyl-5-(2-(trifluoromethyl)phenyl)pyrrolo[3,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50512278 (CHEMBL4475724) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...				Eur J Med Chem 172: 163-173 (2019) Article DOI: 10.1016/j.ejmech.2019.03.059 BindingDB Entry DOI: 10.7270/Q2028VWB
Yanbian University College of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317380 (CHEMBL1098821 \| methyl 3-(4,6-dioxo-3-stearoylpyrr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM32102 (1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...) Show SMILES Cn1ncnc2c1nc(=O)n(C)c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PCBioAssay	n/a	n/a	349	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The Cdc25B Phosphatase HTS dose response confirmation has been developed to confirm actives identified in the Cdc25B HTS AID 368, screened at the Uni...				PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2BG2MCP
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50106491 (5-Amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human cell division cycle 25B				J Med Chem 44: 4042-9 (2001) BindingDB Entry DOI: 10.7270/Q2X34WR5
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50512277 (CHEMBL4445615) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...				Eur J Med Chem 172: 163-173 (2019) Article DOI: 10.1016/j.ejmech.2019.03.059 BindingDB Entry DOI: 10.7270/Q2028VWB
Yanbian University College of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM32102 (1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...) Show SMILES Cn1ncnc2c1nc(=O)n(C)c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PCBioAssay	n/a	n/a	396	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2125R2H
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50033731 ((R)-5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Montana State University Curated by ChEMBL					Assay Description Inhibition of recombinant Cdc25B (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assay				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111719 BindingDB Entry DOI: 10.7270/Q2D221X9
Montana State University Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50261252 (CHEMBL511236 \| [((R)-4-Hexadecanoyl-3-hydroxy-5-ox...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of Bayreuth Curated by ChEMBL					Assay Description Inhibition of cdc25B				Bioorg Med Chem 16: 4203-21 (2008) Article DOI: 10.1016/j.bmc.2008.02.069 BindingDB Entry DOI: 10.7270/Q2C24W6P
University of Bayreuth Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM31040 (1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...) Show SMILES CCn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The Cdc25B Phosphatase HTS dose response confirmation has been developed to confirm actives identified in the Cdc25B HTS AID 368, screened at the Uni...				PubChem Bioassay (2006) BindingDB Entry DOI: 10.7270/Q2BG2MCP
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317359 (5-(4-nitrophenyl)-3-stearoylpyrrolo[3,4-c]pyrazole...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317374 (CHEMBL1098791 \| methyl 2-(4,6-dioxo-3-stearoylpyrr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM31044 (1-Ethyl-6-methyl-3-thiophen-2-yl-1H-pyrimido[5,4-e...) Show SMILES CCn1nc(nc2c1nc(=O)n(C)c2=O)-c1cccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	421	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The Cdc25B Phosphatase probe assessment dose response reproducibility assay has been developed to re-confirm actives that were identified in the Cdc2...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q25T3HWF
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50106503 (6-Chloro-7-(2-morpholin-4-yl-ethylamino)-phthalazi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human cell division cycle 25B				J Med Chem 44: 4042-9 (2001) BindingDB Entry DOI: 10.7270/Q2X34WR5
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM31040 (1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...) Show SMILES CCn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	447	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2125R2H
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50106493 (7-[2-(4-Hydroxy-3-methoxy-phenyl)-ethylamino]-quin...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human cell division cycle 25B				J Med Chem 44: 4042-9 (2001) BindingDB Entry DOI: 10.7270/Q2X34WR5
University of Pittsburgh Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317361 (5-(2-fluorophenyl)-3-stearoylpyrrolo[3,4-c]pyrazol...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50512272 (CHEMBL4450252) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Yanbian University College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged CDC25B expressed in Escherichia coli BL21 (DE3) using pNPP as substrate measured for 2 mins by colorimetri...				Eur J Med Chem 172: 163-173 (2019) Article DOI: 10.1016/j.ejmech.2019.03.059 BindingDB Entry DOI: 10.7270/Q2028VWB
Yanbian University College of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317375 (CHEMBL1098792 \| methyl 4-(4,6-dioxo-3-stearoylpyrr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM31040 (1-Ethyl-6-methyl-3-phenyl-1H-pyrimido[5,4-e][1,2,4...) Show SMILES CCn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	493	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description The Cdc25B Phosphatase probe assessment dose response reproducibility assay has been developed to re-confirm actives that were identified in the Cdc2...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q25T3HWF
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50317358 (5-(4-nitrophenyl)-3-tetradecanoylpyrrolo[3,4-c]pyr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of CDC25B				Bioorg Med Chem Lett 20: 2876-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.040 BindingDB Entry DOI: 10.7270/Q2W959CB
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair

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