Compile Data Set for Download or QSAR

Found 51 hits of ic50 data for polymerid = 8986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50017712 ((-)-reserpine | (3beta,16beta,17alpha,18beta,20alp...) Show SMILES CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c1cc(OC)c(OC)c(OC)c1 |r| Show InChI InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	8.5	n/a
Hebrew University of Jerusalem					Assay Description The uptake assay was performed in reaction buffer containing 140 mM K2-tartrate, 10 mM Tricine, 10 mM Tris, and 5 mM MgCl2, pH 8.5. Liposomes (1 _...				J Biol Chem 288: 32160-71 (2013) Article DOI: 10.1074/jbc.M113.502971 BindingDB Entry DOI: 10.7270/Q20P0XVW
					More data for this Ligand-Target Pair				3D Structure (crystal)
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573715 (CHEMBL4874676) Show SMILES CCCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573730 (CHEMBL4873900) Show SMILES COc1cc2CCN3CC(CC(C)C)C(O)(CO)CC3c2cc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573717 (CHEMBL4854730) Show SMILES COc1cc2C3CC(O)C(CC(C)C)CN3CCc2cc1OCC(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573716 (CHEMBL4874168) Show SMILES CCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573713 (CHEMBL4859304) Show SMILES COc1cc2C3CC(O)C(CC(C)C)CN3CCc2cc1OCC1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573717 (CHEMBL4854730) Show SMILES COc1cc2C3CC(O)C(CC(C)C)CN3CCc2cc1OCC(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573730 (CHEMBL4873900) Show SMILES COc1cc2CCN3CC(CC(C)C)C(O)(CO)CC3c2cc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50017701 (3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-...) Show SMILES COc1cc2CCN3CC(CC(C)C)C(=O)CC3c2cc1OC Show InChI InChI=1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	8.30	5.20	n/a	n/a	n/a	7.5	25
Hebrew University of Jerusalem					Assay Description Liposomes (1-2 ul) were added to 200 ul of reaction buffer containing 150 mM NaCl, 15 mM Tris-HCl, pH 7.5, and increasing concentrations of [3H]TBZOH...				J Biol Chem 288: 32160-71 (2013) Article DOI: 10.1074/jbc.M113.502971 BindingDB Entry DOI: 10.7270/Q20P0XVW
					More data for this Ligand-Target Pair				3D Structure (crystal)
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50342818 ((3S,11BS)-TETRABENAZINE | CHEMBL519344) Show SMILES COc1cc2CCN3C[C@H](CC(C)C)C(=O)C[C@H]3c2cc1OC |r| Show InChI InChI=1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573724 (CHEMBL4871801) Show SMILES CCCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OCC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573716 (CHEMBL4874168) Show SMILES CCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50301021 ((+)-dihydrotetrabenzaine | CHEMBL576222 | US110532...) Show SMILES COc1cc2CCN3C[C@@H](CC(C)C)[C@H](O)C[C@@H]3c2cc1OC |r| Show InChI InChI=1S/C19H29NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16-17,21H,5-7,10-11H2,1-4H3/t14-,16-,17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573713 (CHEMBL4859304) Show SMILES COc1cc2C3CC(O)C(CC(C)C)CN3CCc2cc1OCC1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50301021 ((+)-dihydrotetrabenzaine | CHEMBL576222 | US110532...) Show SMILES COc1cc2CCN3C[C@@H](CC(C)C)[C@H](O)C[C@@H]3c2cc1OC |r| Show InChI InChI=1S/C19H29NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16-17,21H,5-7,10-11H2,1-4H3/t14-,16-,17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573726 (CHEMBL4878776) Show SMILES CCOc1cc2C3CC(O)C(CC(C)C)CN3CCc2cc1OCC1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573731 (CHEMBL4860699) Show SMILES COc1cc2CCN3CC(CC(C)C)C(O)(CC3c2cc1OC)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573715 (CHEMBL4874676) Show SMILES CCCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573723 (CHEMBL4875286) Show SMILES CCOc1cc2C3CC(O)C(CC(C)C)CN3CCc2cc1OCCCF Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573714 (CHEMBL4867332) Show SMILES COCCCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM637602 (US20230382919, Compound 17) Show SMILES C1CNCc2c(C1)oc1ccccc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573714 (CHEMBL4867332) Show SMILES COCCCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopC...				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50597228 (CHEMBL5176306) Show SMILES Cl.[H][C@]12C[C@H](CC)[C@]3([H])N(C1)CCc1c(n(CC)c4ccc(O)cc14)[C@]3([H])C2 |r,TLB:15:14:10.2.27:7,5:4:9.10:27.25,24:13:10.2.27:7,3:2:14.13.12.11:7,THB:14:25:9.10:4.3,11:9:27.25:4.3| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00214 BindingDB Entry DOI: 10.7270/Q2BR8X66
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50342818 ((3S,11BS)-TETRABENAZINE | CHEMBL519344) Show SMILES COc1cc2CCN3C[C@H](CC(C)C)C(=O)C[C@H]3c2cc1OC |r| Show InChI InChI=1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573718 (CHEMBL4862715) Show SMILES CCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OCCCOC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50597220 (CHEMBL5207655) Show SMILES [H][C@]12C[C@H](CC)[C@]3([H])N(C1)CCc1c([nH]c4ccc(OCC)cc14)[C@]3([H])C2 |r,TLB:4:3:24.26:9.8,2:1:6:12.13.10.11,23:12:26.1.9:6,14:13:26.1.9:6,THB:10:8:24.26:3.2,13:24:9.8:3.2| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00214 BindingDB Entry DOI: 10.7270/Q2BR8X66
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573731 (CHEMBL4860699) Show SMILES COc1cc2CCN3CC(CC(C)C)C(O)(CC3c2cc1OC)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50301023 (3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-...) Show SMILES COc1cc2CCN3CC(CC(C)C)C(N)CC3c2cc1OC Show InChI InChI=1S/C19H30N2O2/c1-12(2)7-14-11-21-6-5-13-8-18(22-3)19(23-4)9-15(13)17(21)10-16(14)20/h8-9,12,14,16-17H,5-7,10-11,20H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50597225 (CHEMBL5207764) Show SMILES Cl.[H][C@]12C[C@H](CC)[C@]3([H])N(C1)CCc1c(n(C)c4ccc(O)cc14)[C@]3([H])C2 |r,TLB:5:4:24.26:10.9,3:2:7:13.14.11.12,23:13:26.2.10:7,15:14:26.2.10:7,THB:11:9:24.26:4.3,14:24:10.9:4.3| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00214 BindingDB Entry DOI: 10.7270/Q2BR8X66
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573725 (CHEMBL4869605) Show SMILES CCOc1cc2C3CC(O)C(CC(C)C)CN3CCc2cc1OCCCOC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573727 (CHEMBL4857619) Show SMILES CC(C)CC1CN2CCc3cc(OCC4CC4)c(OCC4CC4)cc3C2CC1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573720 (CHEMBL4864621) Show SMILES CCCOc1cc2C3CC(O)C(CC(C)C)CN3CCc2cc1OCC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50597226 (CHEMBL5188930) Show SMILES [H][C@]12C[C@H](CC)[C@]3([H])N(C1)CCc1c(n(C)c4ccc(cc14)C#N)[C@]3([H])C2 |r,TLB:14:13:9.1.26:6,21:12:9.1.26:6,4:3:8.9:26.24,2:1:13.12.11.10:6,THB:13:24:8.9:3.2,10:8:26.24:3.2| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00214 BindingDB Entry DOI: 10.7270/Q2BR8X66
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573729 (CHEMBL4856324) Show SMILES CCCOc1cc2C3CC(O)C(CC(C)C)CN3CCc2cc1OC(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573728 (CHEMBL4877457) Show SMILES CCCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OC(C)C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573721 (CHEMBL4871559) Show SMILES CCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OCCCF Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573719 (CHEMBL4849901) Show SMILES CCOc1cc2CCN3CC(CC(C)C)C(O)CC3c2cc1OCC1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50192902 (2-ethyl-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-he...) Show SMILES CCC1(O)CC2N(CCc3cc(OC)c(OC)cc23)CC1CC(C)C Show InChI InChI=1S/C21H33NO3/c1-6-21(23)12-18-17-11-20(25-5)19(24-4)10-15(17)7-8-22(18)13-16(21)9-14(2)3/h10-11,14,16,18,23H,6-9,12-13H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573732 (CHEMBL4867056) Show SMILES COc1cc2CCN3CC(CC(C)C)C(C)(O)CC3c2cc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50573722 (CHEMBL4849938) Show SMILES CCOc1cc2C3CC(O)C(CC(C)C)CN3CCc2cc1OC Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]DTBZ binding to VMAT2 in rat brain incubated for 30 mins by liquid scintillation spectrometry analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113718 BindingDB Entry DOI: 10.7270/Q2CN77QJ
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50597219 (CHEMBL5202868) Show SMILES [H][C@@]12C[C@H](CC)[C@@]3([H])C(C1)c1[nH]c4ccc(O)cc4c1CCN3C2 |r,TLB:2:1:6:19.10.21.20,18:19:9.1.23:6,11:10:9.1.23:6,THB:4:3:8.9:23.22,21:22:8.9:3.2,10:8:23.22:3.2| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00214 BindingDB Entry DOI: 10.7270/Q2BR8X66
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50597224 (CHEMBL5171433) Show SMILES [H][C@]12C[C@H](CC)[C@]3([H])N(C1)CCc1c(n(C)c4ccc(OC)cc14)[C@]3([H])C2 |r,TLB:4:3:24.26:9.8,2:1:6:12.13.10.11,23:12:26.1.9:6,14:13:26.1.9:6,THB:10:8:24.26:3.2,13:24:9.8:3.2| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00214 BindingDB Entry DOI: 10.7270/Q2BR8X66
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50597227 (CHEMBL5180373) Show SMILES [H][C@]12C[C@H](CC)[C@]3([H])N(C1)CCc1c(n(C)c4ccc(CC)cc14)[C@]3([H])C2 |r,TLB:4:3:24.26:9.8,2:1:6:12.13.10.11,23:12:26.1.9:6,14:13:26.1.9:6,THB:10:8:24.26:3.2,13:24:9.8:3.2| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00214 BindingDB Entry DOI: 10.7270/Q2BR8X66
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM637600 (US20230382919, Compound 16) Show SMILES C1Cc2oc3ccccc3c2CCN1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50597223 (CHEMBL5201219) Show SMILES [H][C@]12C[C@H](CC)[C@]3([H])N(C1)CCc1c(n(C)c4ccccc14)[C@]3([H])C2 |r,TLB:14:13:9.1.24:6,4:3:8.9:24.22,21:12:9.1.24:6,2:1:13.12.11.10:6,THB:13:22:8.9:3.2,10:8:24.22:3.2| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00214 BindingDB Entry DOI: 10.7270/Q2BR8X66
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50597222 (CHEMBL5184088) Show SMILES [H][C@]12C[C@H](CC)[C@]3([H])N(C1)CCc1c([nH]c4ccccc14)[C@]3([H])C2 |r,TLB:4:3:21.23:9.8,20:12:23.1.9:6,2:1:6:12.13.10.11,14:13:23.1.9:6,THB:10:8:21.23:3.2,13:21:9.8:3.2| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00214 BindingDB Entry DOI: 10.7270/Q2BR8X66
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50597221 (CHEMBL5175119) Show SMILES [H][C@]12C[C@H](CC)[C@]3([H])N(C1)CCc1c([nH]c4ccc(cc14)C#N)[C@]3([H])C2 |r,TLB:4:3:23.25:9.8,2:1:6:12.13.10.11,20:12:25.1.9:6,14:13:25.1.9:6,THB:10:8:23.25:3.2,13:23:9.8:3.2| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00214 BindingDB Entry DOI: 10.7270/Q2BR8X66
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50308247 (CHEMBL1215855) Show SMILES [H][C@]12C[C@H](CC)[C@]3([H])N(C1)CCc1c([nH]c4ccc(OC)cc14)[C@]3([H])C2 |@@:8,TLB:2:1:6:13.12.10.11,THB:13:23:8.9:3.2,10:8:23.25:3.2| Show InChI InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13+,17+,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00214 BindingDB Entry DOI: 10.7270/Q2BR8X66
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM637601 (US20230382919, Compound 25) Show SMILES CN1CCc2oc3ccccc3c2CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Synaptic vesicular amine transporter (Rattus norvegicus (Rat))	BDBM50597229 (CHEMBL5188726) Show SMILES [H][C@]12C[C@H](CC)[C@]3([H])N(C1)CCc1c([nH]c4ccc(OC)c(Br)c14)[C@]3([H])C2 |r,TLB:4:3:24.26:9.8,2:1:6:12.13.10.11,23:12:26.1.9:6,14:13:26.1.9:6,THB:10:8:24.26:3.2,13:24:9.8:3.2| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00214 BindingDB Entry DOI: 10.7270/Q2BR8X66
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 51 total )  |  Next  |  Last  >>

Jump to: