Compile Data Set for Download or QSAR

Found 46 hits of ki data for polymerid = 50001449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106431 (1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C17H11NO7/c19-11-2-1-7(4-12(11)20)16(23)15-9-6-14(22)13(21)5-8(9)3-10(18-15)17(24)25/h1-6,19-22H,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106431 (1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C17H11NO7/c19-11-2-1-7(4-12(11)20)16(23)15-9-6-14(22)13(21)5-8(9)3-10(18-15)17(24)25/h1-6,19-22H,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106443 (1-(3,4-Dihydroxy-benzyl)-6,7-dihydroxy-isoquinolin...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(Cc2ccc(O)c(O)c2)n1 Show InChI InChI=1S/C17H13NO6/c19-13-2-1-8(4-14(13)20)3-11-10-7-16(22)15(21)6-9(10)5-12(18-11)17(23)24/h1-2,4-7,19-22H,3H2,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128459 (4-(3,4-Dihydroxy-benzyl)-6,7-dihydroxy-quinoline-2...) Show SMILES OC(=O)c1cc(Cc2ccc(O)c(O)c2)c2cc(O)c(O)cc2n1 Show InChI InChI=1S/C17H13NO6/c19-13-2-1-8(4-14(13)20)3-9-5-12(17(23)24)18-11-7-16(22)15(21)6-10(9)11/h1-2,4-7,19-22H,3H2,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability of compound to displace Insulin-Like Growth Factor (IGF-I) from its binding to Insulin-like growth factor binding protein 3 (IGFBP-3)				Bioorg Med Chem Lett 13: 1931-4 (2003) BindingDB Entry DOI: 10.7270/Q2XD1138
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128442 (1-[4-(3,5-Dichloro-phenoxy)-3-fluoro-benzoyl]-6,7-...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(Oc2cc(Cl)cc(Cl)c2)c(F)c1 Show InChI InChI=1S/C23H12Cl2FNO6/c24-12-6-13(25)8-14(7-12)33-20-2-1-10(3-16(20)26)22(30)21-15-9-19(29)18(28)5-11(15)4-17(27-21)23(31)32/h1-9,28-29H,(H,31,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128432 (1-(3-Fluoro-4-p-tolyloxy-benzoyl)-6,7-dihydroxy-is...) Show SMILES Cc1ccc(Oc2ccc(cc2F)C(=O)c2nc(cc3cc(O)c(O)cc23)C(O)=O)cc1 Show InChI InChI=1S/C24H16FNO6/c1-12-2-5-15(6-3-12)32-21-7-4-13(8-17(21)25)23(29)22-16-11-20(28)19(27)10-14(16)9-18(26-22)24(30)31/h2-11,27-28H,1H3,(H,30,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128450 (1-[4-(3-Chloro-phenoxy)-3-fluoro-benzoyl]-6,7-dihy...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(Oc2cccc(Cl)c2)c(F)c1 Show InChI InChI=1S/C23H13ClFNO6/c24-13-2-1-3-14(9-13)32-20-5-4-11(6-16(20)25)22(29)21-15-10-19(28)18(27)8-12(15)7-17(26-21)23(30)31/h1-10,27-28H,(H,30,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128452 (6,7-Dihydroxy-1-[hydroxy-(2,4,6-trimethyl-phenyl)-...) Show SMILES Cc1cc(C)c(C(O)c2nc(cc3cc(O)c(O)cc23)C(O)=O)c(C)c1 Show InChI InChI=1S/C20H19NO5/c1-9-4-10(2)17(11(3)5-9)19(24)18-13-8-16(23)15(22)7-12(13)6-14(21-18)20(25)26/h4-8,19,22-24H,1-3H3,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128451 (1-[4-(3,4-Dichloro-phenoxy)-3-fluoro-benzoyl]-6,7-...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(Oc2ccc(Cl)c(Cl)c2)c(F)c1 Show InChI InChI=1S/C23H12Cl2FNO6/c24-14-3-2-12(8-15(14)25)33-20-4-1-10(5-16(20)26)22(30)21-13-9-19(29)18(28)7-11(13)6-17(27-21)23(31)32/h1-9,28-29H,(H,31,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106446 (6,7-Dihydroxy-1-(naphthalene-2-carbonyl)-isoquinol...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C21H13NO5/c23-17-9-14-8-16(21(26)27)22-19(15(14)10-18(17)24)20(25)13-6-5-11-3-1-2-4-12(11)7-13/h1-10,23-24H,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128430 (6,7-Dihydroxy-1-[hydroxy-(4-trifluoromethyl-phenyl...) Show SMILES OC(c1ccc(cc1)C(F)(F)F)c1nc(cc2cc(O)c(O)cc12)C(O)=O Show InChI InChI=1S/C18H12F3NO5/c19-18(20,21)10-3-1-8(2-4-10)16(25)15-11-7-14(24)13(23)6-9(11)5-12(22-15)17(26)27/h1-7,16,23-25H,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128454 (1-[4-(4-Chloro-phenoxy)-3-fluoro-benzoyl]-6,7-dihy...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(Oc2ccc(Cl)cc2)c(F)c1 Show InChI InChI=1S/C23H13ClFNO6/c24-13-2-4-14(5-3-13)32-20-6-1-11(7-16(20)25)22(29)21-15-10-19(28)18(27)9-12(15)8-17(26-21)23(30)31/h1-10,27-28H,(H,30,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128433 (1-[(3-Fluoro-phenyl)-hydroxy-methyl]-6,7-dihydroxy...) Show SMILES OC(c1cccc(F)c1)c1nc(cc2cc(O)c(O)cc12)C(O)=O Show InChI InChI=1S/C17H12FNO5/c18-10-3-1-2-8(4-10)16(22)15-11-7-14(21)13(20)6-9(11)5-12(19-15)17(23)24/h1-7,16,20-22H,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128438 (1-[(2-Chloro-phenyl)-hydroxy-methyl]-6,7-dihydroxy...) Show SMILES OC(c1ccccc1Cl)c1nc(cc2cc(O)c(O)cc12)C(O)=O Show InChI InChI=1S/C17H12ClNO5/c18-11-4-2-1-3-9(11)16(22)15-10-7-14(21)13(20)6-8(10)5-12(19-15)17(23)24/h1-7,16,20-22H,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106439 (6,7-Dihydroxy-1-(naphthalene-1-carbonyl)-isoquinol...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C21H13NO5/c23-17-9-12-8-16(21(26)27)22-19(15(12)10-18(17)24)20(25)14-7-3-5-11-4-1-2-6-13(11)14/h1-10,23-24H,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106432 ((3,4-Dihydroxy-phenyl)-(3,6,7-trihydroxy-isoquinol...) Show SMILES Oc1ccc(cc1O)C(=O)c1[nH]c(=O)cc2cc(O)c(O)cc12 Show InChI InChI=1S/C16H11NO6/c18-10-2-1-7(3-11(10)19)16(23)15-9-6-13(21)12(20)4-8(9)5-14(22)17-15/h1-6,18-21H,(H,17,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128447 (1-(3,4-Dichloro-benzoyl)-6,7-dihydroxy-isoquinolin...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C17H9Cl2NO5/c18-10-2-1-7(3-11(10)19)16(23)15-9-6-14(22)13(21)5-8(9)4-12(20-15)17(24)25/h1-6,21-22H,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106441 (1-(3,4-Dihydroxy-benzyl)-isoquinoline-3,6,7-triol ...) Show SMILES Oc1ccc(Cc2[nH]c(=O)cc3cc(O)c(O)cc23)cc1O Show InChI InChI=1S/C16H13NO5/c18-12-2-1-8(4-13(12)19)3-11-10-7-15(21)14(20)5-9(10)6-16(22)17-11/h1-2,4-7,18-21H,3H2,(H,17,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128434 (1-[4-(4-Chloro-phenylsulfanyl)-3-fluoro-benzoyl]-6...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(Sc2ccc(Cl)cc2)c(F)c1 Show InChI InChI=1S/C23H13ClFNO5S/c24-13-2-4-14(5-3-13)32-20-6-1-11(7-16(20)25)22(29)21-15-10-19(28)18(27)9-12(15)8-17(26-21)23(30)31/h1-10,27-28H,(H,30,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128431 (1-[3-Fluoro-4-(4-trifluoromethyl-phenoxy)-benzoyl]...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(Oc2ccc(cc2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C24H13F4NO6/c25-16-7-11(1-6-20(16)35-14-4-2-13(3-5-14)24(26,27)28)22(32)21-15-10-19(31)18(30)9-12(15)8-17(29-21)23(33)34/h1-10,30-31H,(H,33,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128446 (6,7-Dihydroxy-1-(4-nitro-benzoyl)-isoquinoline-3-c...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C17H10N2O7/c20-13-6-9-5-12(17(23)24)18-15(11(9)7-14(13)21)16(22)8-1-3-10(4-2-8)19(25)26/h1-7,20-21H,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128443 (6,7-Dihydroxy-1-[hydroxy-(4-phenoxy-phenyl)-methyl...) Show SMILES OC(c1ccc(Oc2ccccc2)cc1)c1nc(cc2cc(O)c(O)cc12)C(O)=O Show InChI InChI=1S/C23H17NO6/c25-19-11-14-10-18(23(28)29)24-21(17(14)12-20(19)26)22(27)13-6-8-16(9-7-13)30-15-4-2-1-3-5-15/h1-12,22,25-27H,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128436 (1-[4-(Biphenyl-4-yloxy)-3-fluoro-benzoyl]-6,7-dihy...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(Oc2ccc(cc2)-c2ccccc2)c(F)c1 Show InChI InChI=1S/C29H18FNO6/c30-22-12-18(8-11-26(22)37-20-9-6-17(7-10-20)16-4-2-1-3-5-16)28(34)27-21-15-25(33)24(32)14-19(21)13-23(31-27)29(35)36/h1-15,32-33H,(H,35,36)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128437 (6,7-Dihydroxy-1-(4-trifluoromethyl-benzoyl)-isoqui...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H10F3NO5/c19-18(20,21)10-3-1-8(2-4-10)16(25)15-11-7-14(24)13(23)6-9(11)5-12(22-15)17(26)27/h1-7,23-24H,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106433 (1-(2,4-Dichloro-benzoyl)-6,7-dihydroxy-isoquinolin...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C17H9Cl2NO5/c18-8-1-2-9(11(19)5-8)16(23)15-10-6-14(22)13(21)4-7(10)3-12(20-15)17(24)25/h1-6,21-22H,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128455 (1-(3,4-Difluoro-benzoyl)-6,7-dihydroxy-isoquinolin...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(F)c(F)c1 Show InChI InChI=1S/C17H9F2NO5/c18-10-2-1-7(3-11(10)19)16(23)15-9-6-14(22)13(21)5-8(9)4-12(20-15)17(24)25/h1-6,21-22H,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106436 ((6,7-Dihydroxy-isoquinolin-1-yl)-(3,4-dihydroxy-ph...) Show SMILES Oc1ccc(cc1O)C(=O)c1nccc2cc(O)c(O)cc12 Show InChI InChI=1S/C16H11NO5/c18-11-2-1-9(6-12(11)19)16(22)15-10-7-14(21)13(20)5-8(10)3-4-17-15/h1-7,18-21H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128444 (6-Amino-1-(3,4-dihydroxy-benzoyl)-7-hydroxy-isoqui...) Show SMILES Nc1cc2cc(nc(C(=O)c3ccc(O)c(O)c3)c2cc1O)C(O)=O Show InChI InChI=1S/C17H12N2O6/c18-10-3-8-4-11(17(24)25)19-15(9(8)6-13(10)21)16(23)7-1-2-12(20)14(22)5-7/h1-6,20-22H,18H2,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128440 (1-[4-(2-Ethyl-hexylamino)-3-fluoro-benzoyl]-6,7-di...) Show SMILES CCCCC(CC)CNc1ccc(cc1F)C(=O)c1nc(cc2cc(O)c(O)cc12)C(O)=O Show InChI InChI=1S/C25H27FN2O5/c1-3-5-6-14(4-2)13-27-19-8-7-15(9-18(19)26)24(31)23-17-12-22(30)21(29)11-16(17)10-20(28-23)25(32)33/h7-12,14,27,29-30H,3-6,13H2,1-2H3,(H,32,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106438 (1-(Benzo[1,3]dioxole-5-carbonyl)-6,7-dihydroxy-iso...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C18H11NO7/c20-12-4-9-3-11(18(23)24)19-16(10(9)6-13(12)21)17(22)8-1-2-14-15(5-8)26-7-25-14/h1-6,20-21H,7H2,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106437 (5-Bromo-1-(3,4-dihydroxy-benzoyl)-6-hydroxy-7-meth...) Show SMILES COc1cc2c(nc(cc2c(Br)c1O)C(O)=O)C(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C18H12BrNO7/c1-27-13-6-9-8(14(19)17(13)24)5-10(18(25)26)20-15(9)16(23)7-2-3-11(21)12(22)4-7/h2-6,21-22,24H,1H3,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106438 (1-(Benzo[1,3]dioxole-5-carbonyl)-6,7-dihydroxy-iso...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C18H11NO7/c20-12-4-9-3-11(18(23)24)19-16(10(9)6-13(12)21)17(22)8-1-2-14-15(5-8)26-7-25-14/h1-6,20-21H,7H2,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128439 (1-Benzo[1,3]dioxol-5-ylmethyl-6,7-dihydroxy-isoqui...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(Cc2ccc3OCOc3c2)n1 Show InChI InChI=1S/C18H13NO6/c20-14-6-10-5-13(18(22)23)19-12(11(10)7-15(14)21)3-9-1-2-16-17(4-9)25-8-24-16/h1-2,4-7,20-21H,3,8H2,(H,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128435 (6,7-Dihydroxy-1-(2,4,6-trimethyl-benzoyl)-isoquino...) Show SMILES Cc1cc(C)c(C(=O)c2nc(cc3cc(O)c(O)cc23)C(O)=O)c(C)c1 Show InChI InChI=1S/C20H17NO5/c1-9-4-10(2)17(11(3)5-9)19(24)18-13-8-16(23)15(22)7-12(13)6-14(21-18)20(25)26/h4-8,22-23H,1-3H3,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128453 (1-(2-Chloro-benzoyl)-6,7-dihydroxy-isoquinoline-3-...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccccc1Cl Show InChI InChI=1S/C17H10ClNO5/c18-11-4-2-1-3-9(11)16(22)15-10-7-14(21)13(20)6-8(10)5-12(19-15)17(23)24/h1-7,20-21H,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128441 (6,7-Dihydroxy-1-(4-methanesulfonylamino-benzoyl)-i...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)C(=O)c1nc(cc2cc(O)c(O)cc12)C(O)=O Show InChI InChI=1S/C18H14N2O7S/c1-28(26,27)20-11-4-2-9(3-5-11)17(23)16-12-8-15(22)14(21)7-10(12)6-13(19-16)18(24)25/h2-8,20-22H,1H3,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128449 (1-(3-Fluoro-benzoyl)-6,7-dihydroxy-isoquinoline-3-...) Show SMILES OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1cccc(F)c1 Show InChI InChI=1S/C17H10FNO5/c18-10-3-1-2-8(4-10)16(22)15-11-7-14(21)13(20)6-9(11)5-12(19-15)17(23)24/h1-7,20-21H,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128448 (1-(4-Amino-benzoyl)-6,7-dihydroxy-isoquinoline-3-c...) Show SMILES Nc1ccc(cc1)C(=O)c1nc(cc2cc(O)c(O)cc12)C(O)=O Show InChI InChI=1S/C17H12N2O5/c18-10-3-1-8(2-4-10)16(22)15-11-7-14(21)13(20)6-9(11)5-12(19-15)17(23)24/h1-7,20-21H,18H2,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106440 (8-Bromo-1-(3,4-dihydroxy-benzoyl)-7-hydroxy-6-meth...) Show SMILES COc1cc2cc(nc(C(=O)c3ccc(O)c(O)c3)c2c(Br)c1O)C(O)=O Show InChI InChI=1S/C18H12BrNO7/c1-27-12-6-8-4-9(18(25)26)20-15(13(8)14(19)17(12)24)16(23)7-2-3-10(21)11(22)5-7/h2-6,21-22,24H,1H3,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106435 (7-Hydroxy-1-(3-hydroxy-4-methoxy-benzoyl)-6-methox...) Show SMILES COc1ccc(cc1O)C(=O)c1nc(cc2cc(OC)c(O)cc12)C(O)=O Show InChI InChI=1S/C19H15NO7/c1-26-15-4-3-9(6-13(15)21)18(23)17-11-8-14(22)16(27-2)7-10(11)5-12(20-17)19(24)25/h3-8,21-22H,1-2H3,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128445 (6-Amino-1-(benzo[1,3]dioxole-5-carbonyl)-7-hydroxy...) Show SMILES Nc1cc2cc(nc(C(=O)c3ccc4OCOc4c3)c2cc1O)C(O)=O Show InChI InChI=1S/C18H12N2O6/c19-11-3-9-4-12(18(23)24)20-16(10(9)6-13(11)21)17(22)8-1-2-14-15(5-8)26-7-25-14/h1-6,21H,7,19H2,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106442 (1-(3,4-Dihydroxy-benzoyl)-6,7-dimethoxy-isoquinoli...) Show SMILES COc1cc2cc(nc(C(=O)c3ccc(O)c(O)c3)c2cc1OC)C(O)=O Show InChI InChI=1S/C19H15NO7/c1-26-15-7-10-5-12(19(24)25)20-17(11(10)8-16(15)27-2)18(23)9-3-4-13(21)14(22)6-9/h3-8,21-22H,1-2H3,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106434 (1-(3,4-Dimethoxy-benzoyl)-6,7-dimethoxy-isoquinoli...) Show SMILES CCOC(=O)c1cc2cc(OC)c(OC)cc2c(n1)C(=O)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C23H23NO7/c1-6-31-23(26)16-9-14-11-19(29-4)20(30-5)12-15(14)21(24-16)22(25)13-7-8-17(27-2)18(10-13)28-3/h7-12H,6H2,1-5H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106444 (1-(3-Hydroxy-4-methoxy-benzoyl)-6,7-dimethoxy-isoq...) Show SMILES COc1ccc(cc1O)C(=O)c1nc(cc2cc(OC)c(OC)cc12)C(O)=O Show InChI InChI=1S/C20H17NO7/c1-26-15-5-4-10(7-14(15)22)19(23)18-12-9-17(28-3)16(27-2)8-11(12)6-13(21-18)20(24)25/h4-9,22H,1-3H3,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50106445 ((3,4-Dimethoxy-phenyl)-(3-hydroxy-6,7-dimethoxy-is...) Show SMILES COc1ccc(cc1OC)C(=O)c1[nH]c(=O)cc2cc(OC)c(OC)cc12 Show InChI InChI=1S/C20H19NO6/c1-24-14-6-5-11(7-15(14)25-2)20(23)19-13-10-17(27-4)16(26-3)8-12(13)9-18(22)21-19/h5-10H,1-4H3,(H,21,22)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Insulin-like growth factor binding protein 3				J Med Chem 44: 4001-10 (2001) BindingDB Entry DOI: 10.7270/Q2F18Z12
					More data for this Ligand-Target Pair
Insulin-like growth factor-binding protein 3 (Homo sapiens (Human))	BDBM50128429 (1-(Benzo[1,3]dioxole-5-carbonyl)-7-hydroxy-6-metha...) Show SMILES CS(=O)(=O)Nc1cc2cc(nc(C(=O)c3ccc4OCOc4c3)c2cc1O)C(O)=O Show InChI InChI=1S/C19H14N2O8S/c1-30(26,27)21-12-4-10-5-13(19(24)25)20-17(11(10)7-14(12)22)18(23)9-2-3-15-16(6-9)29-8-28-15/h2-7,21-22H,8H2,1H3,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)				Bioorg Med Chem Lett 13: 1927-30 (2003) BindingDB Entry DOI: 10.7270/Q2251HK5
					More data for this Ligand-Target Pair