Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50612995 (CHEMBL5276586) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50612998 (CHEMBL5269400) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50613001 (CHEMBL5268739) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | 0.690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50613004 (CHEMBL5282029) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50612994 (CHEMBL5283777) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | UniChem | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50333455 ((2S,3S,4S,5S)-2-butyl-5-(hydroxymethyl)pyrrolidine...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama Curated by ChEMBL | Assay Description Competitive inhibition of rat intestinal maltase by Lineweaver-Burk plot analysis | J Med Chem 55: 10347-62 (2012) Article DOI: 10.1021/jm301304e BindingDB Entry DOI: 10.7270/Q2K35VTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50242818 (1-Oxo-1lambda-4-thia-cyclotridecan-3,4,5,6,8,10,11...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fuji-Sangyo Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of rat intestinal maltase | J Nat Prod 71: 981-4 (2008) Article DOI: 10.1021/np070604h BindingDB Entry DOI: 10.7270/Q2XS5W9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50242271 ((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toyama Curated by ChEMBL | Assay Description Competitive inhibition of rat intestinal maltase by Lineweaver-Burk plot analysis | J Med Chem 55: 10347-62 (2012) Article DOI: 10.1021/jm301304e BindingDB Entry DOI: 10.7270/Q2K35VTX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50316179 ((1S,2R,3R,4S)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fuji-Sangyo Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of rat intestinal maltase | J Nat Prod 71: 981-4 (2008) Article DOI: 10.1021/np070604h BindingDB Entry DOI: 10.7270/Q2XS5W9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50330955 ((1S,2S)-3-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymeth...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 970 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Fuji-Sangyo Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of rat intestinal maltase | J Nat Prod 71: 981-4 (2008) Article DOI: 10.1021/np070604h BindingDB Entry DOI: 10.7270/Q2XS5W9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Competitive inhibition of rat alpha-glucosidase assessed as production of chromogenic p-Nitrphenol measured after 3 mins by HPLC and Michaelis-Menton... | Bioorg Med Chem Lett 21: 2441-4 (2011) Article DOI: 10.1016/j.bmcl.2011.02.062 BindingDB Entry DOI: 10.7270/Q2Z60PCK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50438500 (CHEMBL2414822) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Competitive inhibition of rat intestinal maltase using maltose as substrate by Lineweaver-Burk plot analysis | Bioorg Med Chem 21: 5442-50 (2013) Article DOI: 10.1016/j.bmc.2013.06.002 BindingDB Entry DOI: 10.7270/Q2HD7X24 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50439692 (CHEMBL2418233) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chulalongkorn University Curated by ChEMBL | Assay Description Competitive inhibition of rat intestine maltase using maltose as substrate by Lineweaver-Burk plot analysis | Eur J Med Chem 66: 296-304 (2013) Article DOI: 10.1016/j.ejmech.2013.05.047 BindingDB Entry DOI: 10.7270/Q2X63PCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50439692 (CHEMBL2418233) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chulalongkorn University Curated by ChEMBL | Assay Description Non-competitive inhibition of rat intestine maltase using maltose as substrate by Lineweaver-Burk plot analysis | Eur J Med Chem 66: 296-304 (2013) Article DOI: 10.1016/j.ejmech.2013.05.047 BindingDB Entry DOI: 10.7270/Q2X63PCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50208826 ((+)-Pinoresinol | 4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 2.88E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chulalongkorn University Curated by ChEMBL | Assay Description Competitive inhibition of rat intestinal maltase using maltose as substrate assessed as dissociation of enzyme-inhibitor complex at 0.1 to 1 mg/ml by... | Bioorg Med Chem Lett 22: 5215-7 (2012) Article DOI: 10.1016/j.bmcl.2012.06.068 BindingDB Entry DOI: 10.7270/Q28G8MR8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50123930 (CHEMBL3621759) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chulalongkorn University Curated by ChEMBL | Assay Description Non-competitive inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by Lineweaver-Burk plot ana... | Bioorg Med Chem Lett 25: 4529-33 (2015) Article DOI: 10.1016/j.bmcl.2015.08.069 BindingDB Entry DOI: 10.7270/Q2WD42C3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50123929 (CHEMBL3621760) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chulalongkorn University Curated by ChEMBL | Assay Description Non-competitive inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by Lineweaver-Burk plot ana... | Bioorg Med Chem Lett 25: 4529-33 (2015) Article DOI: 10.1016/j.bmcl.2015.08.069 BindingDB Entry DOI: 10.7270/Q2WD42C3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50208826 ((+)-Pinoresinol | 4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 1.34E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chulalongkorn University Curated by ChEMBL | Assay Description Non-competitive inhibition of rat intestinal maltase using maltose as substrate assessed as dissociation of enzyme-substrate-inhibitor complex at 0.1... | Bioorg Med Chem Lett 22: 5215-7 (2012) Article DOI: 10.1016/j.bmcl.2012.06.068 BindingDB Entry DOI: 10.7270/Q28G8MR8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50123930 (CHEMBL3621759) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.64E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chulalongkorn University Curated by ChEMBL | Assay Description Competitive inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by Lineweaver-Burk plot analysi... | Bioorg Med Chem Lett 25: 4529-33 (2015) Article DOI: 10.1016/j.bmcl.2015.08.069 BindingDB Entry DOI: 10.7270/Q2WD42C3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal alpha-glucosidase (Rattus norvegicus) | BDBM50123929 (CHEMBL3621760) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.96E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chulalongkorn University Curated by ChEMBL | Assay Description Competitive inhibition of rat intestinal Maltase using maltose as substrate assessed as glucose release after 10 mins by Lineweaver-Burk plot analysi... | Bioorg Med Chem Lett 25: 4529-33 (2015) Article DOI: 10.1016/j.bmcl.2015.08.069 BindingDB Entry DOI: 10.7270/Q2WD42C3 | |||||||||||
More data for this Ligand-Target Pair |