Compile Data Set for Download or QSAR

Found 98 hits Enz. Inhib. hit(s) with Target = 'Adenylate cyclase type I'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenylate cyclase type 1 (Bos taurus)	BDBM50010259 (Acetic acid 10,10b-dihydroxy-6-{2-[3-(4-hydroxy-ph...) Show SMILES CC(=O)O[C@H]1[C@@H](OC(=O)NCCNC(=O)CCc2ccc(O)cc2)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C Show InChI InChI=1S/C34H48N2O10/c1-8-31(5)19-24(40)34(43)32(6)23(39)15-16-30(3,4)27(32)26(28(44-20(2)37)33(34,7)46-31)45-29(42)36-18-17-35-25(41)14-11-21-9-12-22(38)13-10-21/h8-10,12-13,23,26-28,38-39,43H,1,11,14-19H2,2-7H3,(H,35,41)(H,36,42)/t23-,26-,27-,28-,31-,32-,33+,34-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010260 (CHEMBL107566 | [2-(2-Bromo-acetylamino)-ethyl]-car...) Show SMILES CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](OC(=O)NCCNC(=O)CBr)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C Show InChI InChI=1S/C25H39BrN2O8/c1-7-22(4)12-15(30)25(34)23(5)14(29)8-9-21(2,3)18(23)17(32)19(24(25,6)36-22)35-20(33)28-11-10-27-16(31)13-26/h7,14,17-19,29,32,34H,1,8-13H2,2-6H3,(H,27,31)(H,28,33)/t14-,17-,18-,19-,22-,23-,24+,25-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Binding activity against Adenylate cyclase in bovine brain membrane using [125I]-6-IHPP-Fsk as the radioligand.				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010270 (Acetic acid 6-[2-(2-bromo-acetylamino)-ethylcarbam...) Show SMILES CC(=O)O[C@H]1[C@@H](OC(=O)NCCNC(=O)CBr)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C Show InChI InChI=1S/C27H41BrN2O9/c1-8-24(5)13-17(33)27(36)25(6)16(32)9-10-23(3,4)20(25)19(21(37-15(2)31)26(27,7)39-24)38-22(35)30-12-11-29-18(34)14-28/h8,16,19-21,32,36H,1,9-14H2,2-7H3,(H,29,34)(H,30,35)/t16-,19-,20-,21-,24-,25-,26+,27-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Binding activity against Adenylate cyclase in bovine brain membrane using [125I]-6-IHPP-Fsk as the radioligand.				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010265 (CHEMBL327142 | {2-[3-(4-Hydroxy-phenyl)-propionyla...) Show SMILES CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](OC(=O)NCCNC(=O)CCc1ccc(O)cc1)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C Show InChI InChI=1S/C32H46N2O9/c1-7-29(4)18-22(37)32(41)30(5)21(36)14-15-28(2,3)25(30)24(39)26(31(32,6)43-29)42-27(40)34-17-16-33-23(38)13-10-19-8-11-20(35)12-9-19/h7-9,11-12,21,24-26,35-36,39,41H,1,10,13-18H2,2-6H3,(H,33,38)(H,34,40)/t21-,24-,25-,26-,29-,30-,31+,32-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010261 ((3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10...) Show SMILES CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C |r| Show InChI InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010274 (Acetic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(2-...) Show SMILES CC(=O)O[C@H]1[C@@H](OC(=O)NCCN)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C Show InChI InChI=1S/C25H40N2O8/c1-8-22(5)13-16(30)25(32)23(6)15(29)9-10-21(3,4)18(23)17(34-20(31)27-12-11-26)19(33-14(2)28)24(25,7)35-22/h8,15,17-19,29,32H,1,9-13,26H2,2-7H3,(H,27,31)/t15-,17-,18-,19-,22-,23-,24+,25-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010273 (CHEMBL111738 | {7-[3-(4-Hydroxy-phenyl)-propionyla...) Show SMILES CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](OC(=O)NCCCCCCCNC(=O)CCc1ccc(O)cc1)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C Show InChI InChI=1S/C37H56N2O9/c1-7-34(4)23-27(42)37(46)35(5)26(41)19-20-33(2,3)30(35)29(44)31(36(37,6)48-34)47-32(45)39-22-12-10-8-9-11-21-38-28(43)18-15-24-13-16-25(40)17-14-24/h7,13-14,16-17,26,29-31,40-41,44,46H,1,8-12,15,18-23H2,2-6H3,(H,38,43)(H,39,45)/t26-,29-,30-,31-,34-,35-,36+,37-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010271 (CHEMBL111425 | {4-[3-(4-Hydroxy-phenyl)-propionyla...) Show SMILES CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](OC(=O)NCCCCNC(=O)CCc1ccc(O)cc1)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C Show InChI InChI=1S/C34H50N2O9/c1-7-31(4)20-24(39)34(43)32(5)23(38)16-17-30(2,3)27(32)26(41)28(33(34,6)45-31)44-29(42)36-19-9-8-18-35-25(40)15-12-21-10-13-22(37)14-11-21/h7,10-11,13-14,23,26-28,37-38,41,43H,1,8-9,12,15-20H2,2-6H3,(H,35,40)(H,36,42)/t23-,26-,27-,28-,31-,32-,33+,34-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010269 (CHEMBL327672 | [2-(4-Hydroxy-phenyl)-ethyl]-carbam...) Show SMILES CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](OC(=O)NCCc1ccc(O)cc1)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C Show InChI InChI=1S/C29H41NO8/c1-7-26(4)16-20(33)29(36)27(5)19(32)12-14-25(2,3)22(27)21(34)23(28(29,6)38-26)37-24(35)30-15-13-17-8-10-18(31)11-9-17/h7-11,19,21-23,31-32,34,36H,1,12-16H2,2-6H3,(H,30,35)/t19-,21-,22-,23-,26-,27-,28+,29-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010262 (CHEMBL326703 | {4-[3-(4-Hydroxy-phenyl)-propionyla...) Show SMILES CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](OC(=O)NCCCCNC(=O)CCc1ccc(O)cc1)[C@H](O)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C Show InChI InChI=1S/C34H50N2O9/c1-7-31(4)20-24(39)34(43)32(5)23(38)16-17-30(2,3)27(32)26(28(41)33(34,6)45-31)44-29(42)36-19-9-8-18-35-25(40)15-12-21-10-13-22(37)14-11-21/h7,10-11,13-14,23,26-28,37-38,41,43H,1,8-9,12,15-20H2,2-6H3,(H,35,40)(H,36,42)/t23-,26-,27-,28-,31-,32-,33+,34-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010266 (CHEMBL324659 | {6-[3-(4-Hydroxy-phenyl)-propionyla...) Show SMILES CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](OC(=O)NCCCCCCNC(=O)CCc1ccc(O)cc1)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C Show InChI InChI=1S/C36H54N2O9/c1-7-33(4)22-26(41)36(45)34(5)25(40)18-19-32(2,3)29(34)28(43)30(35(36,6)47-33)46-31(44)38-21-11-9-8-10-20-37-27(42)17-14-23-12-15-24(39)16-13-23/h7,12-13,15-16,25,28-30,39-40,43,45H,1,8-11,14,17-22H2,2-6H3,(H,37,42)(H,38,44)/t25-,28-,29-,30-,33-,34-,35+,36-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010272 (CHEMBL322952 | {6-[3-(4-Hydroxy-phenyl)-propionyla...) Show SMILES CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](OC(=O)NCCCCCCNC(=O)CCc1ccc(O)cc1)[C@H](O)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C Show InChI InChI=1S/C36H54N2O9/c1-7-33(4)22-26(41)36(45)34(5)25(40)18-19-32(2,3)29(34)28(30(43)35(36,6)47-33)46-31(44)38-21-11-9-8-10-20-37-27(42)17-14-23-12-15-24(39)16-13-23/h7,12-13,15-16,25,28-30,39-40,43,45H,1,8-11,14,17-22H2,2-6H3,(H,37,42)(H,38,44)/t25-,28-,29-,30-,33-,34-,35+,36-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010268 ((2-Amino-ethyl)-carbamic acid (3R,4aR,5S,6S,6aS,10...) Show SMILES CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](OC(=O)NCCN)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C Show InChI InChI=1S/C23H38N2O7/c1-7-20(4)12-14(27)23(30)21(5)13(26)8-9-19(2,3)16(21)15(28)17(22(23,6)32-20)31-18(29)25-11-10-24/h7,13,15-17,26,28,30H,1,8-12,24H2,2-6H3,(H,25,29)/t13-,15-,16-,17-,20-,21-,22+,23-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010264 ((2-Isothiocyanato-ethyl)-carbamic acid 6,10,10b-tr...) Show SMILES CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](OC(=O)NCCN=C=S)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C Show InChI InChI=1S/C24H36N2O7S/c1-7-21(4)12-15(28)24(31)22(5)14(27)8-9-20(2,3)17(22)16(29)18(23(24,6)33-21)32-19(30)26-11-10-25-13-34/h7,14,16-18,27,29,31H,1,8-12H2,2-6H3,(H,26,30)/t14-,16-,17-,18-,21-,22-,23+,24-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Binding activity against Adenylate cyclase in bovine brain membrane using [125I]-6-IHPP-Fsk as the radioligand.				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010263 (Acetic acid 10,10b-dihydroxy-6-(2-isothiocyanato-e...) Show SMILES CC(=O)O[C@H]1[C@@H](OC(=O)NCCN=C=S)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C Show InChI InChI=1S/C26H38N2O8S/c1-8-23(5)13-17(31)26(33)24(6)16(30)9-10-22(3,4)19(24)18(35-21(32)28-12-11-27-14-37)20(34-15(2)29)25(26,7)36-23/h8,16,18-20,30,33H,1,9-13H2,2-7H3,(H,28,32)/t16-,18-,19-,20-,23-,24-,25+,26-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Binding activity against Adenylate cyclase in bovine brain membrane using [125I]-6-IHPP-Fsk as the radioligand.				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010275 (CHEMBL324463 | {2-[3-(4-Hydroxy-phenyl)-propionyla...) Show SMILES CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](OC(=O)NCCNC(=O)CCc1ccc(O)cc1)[C@H](O)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C Show InChI InChI=1S/C32H46N2O9/c1-7-29(4)18-22(37)32(41)30(5)21(36)14-15-28(2,3)25(30)24(26(39)31(32,6)43-29)42-27(40)34-17-16-33-23(38)13-10-19-8-11-20(35)12-9-19/h7-9,11-12,21,24-26,35-36,39,41H,1,10,13-18H2,2-6H3,(H,33,38)(H,34,40)/t21-,24-,25-,26-,29-,30-,31+,32-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	174	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 1 (Bos taurus)	BDBM50010267 (CHEMBL92719 | [2-(4-Hydroxy-phenyl)-ethyl]-carbami...) Show SMILES CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](OC(=O)NCCc1ccc(O)cc1)[C@H](O)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C Show InChI InChI=1S/C29H41NO8/c1-7-26(4)16-20(33)29(36)27(5)19(32)12-14-25(2,3)22(27)21(23(34)28(29,6)38-26)37-24(35)30-15-13-17-8-10-18(31)11-9-17/h7-11,19,21-23,31-32,34,36H,1,12-16H2,2-6H3,(H,30,35)/t19-,21-,22-,23-,26-,27-,28+,29-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	236	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 4 (Homo sapiens (Human))	BDBM50226415 (CHEMBL3142312) Show SMILES [#6]-[#6]-[#8]-c1ccc(-[#6]-[#6@@H]-2-[#7]-[#6](=O)-[#6]C([#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c3ccccc3)-[#7]-[#6]-2=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#7])=O)([#6]-2-[#6]-[#6]-[#6]-[#6]-2)[#6]-2-[#6]-[#6]-[#6]-[#6]-2)cc1 Show InChI InChI=1S/C57H87N15O10S2/c1-4-82-38-24-22-35(23-25-38)29-41-50(77)69-42(28-34-14-6-5-7-15-34)52(79)72-47(33(2)3)54(81)70-43(30-45(58)73)51(78)71-44(32-83-84-57(31-46(74)66-41,36-16-8-9-17-36)37-18-10-11-19-37)53(80)68-40(21-13-27-65-56(62)63)49(76)67-39(48(59)75)20-12-26-64-55(60)61/h5-7,14-15,22-25,33,36-37,39-44,47H,4,8-13,16-21,26-32H2,1-3H3,(H2,58,73)(H2,59,75)(H,66,74)(H,67,76)(H,68,80)(H,69,77)(H,70,81)(H,71,78)(H,72,79)(H4,60,61,64)(H4,62,63,65)/t39-,40-,41+,42+,43+,44+,47+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research and Development Division Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperone				J Med Chem 30: 2291-4 (1987) BindingDB Entry DOI: 10.7270/Q2MG7RRN
					More data for this Ligand-Target Pair
Adenylate cyclase type 4 (Homo sapiens (Human))	BDBM50226412 (CHEMBL3142332) Show SMILES [#6]-[#6]-[#8]-c1ccc(-[#6]-[#6@@H]-2-[#7]-[#6](=O)-[#6]C([#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c3ccccc3)-[#7]-[#6]-2=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#7])=O)([#6]-2-[#6]-[#6]-[#6]-[#6]-2)[#6]-2-[#6]-[#6]-[#6]-[#6]-2)cc1 Show InChI InChI=1S/C57H87N15O10S2/c1-4-82-38-24-22-35(23-25-38)29-41-50(77)69-42(28-34-14-6-5-7-15-34)52(79)72-47(33(2)3)54(81)70-43(30-45(58)73)51(78)71-44(32-83-84-57(31-46(74)66-41,36-16-8-9-17-36)37-18-10-11-19-37)53(80)68-40(21-13-27-65-56(62)63)49(76)67-39(48(59)75)20-12-26-64-55(60)61/h5-7,14-15,22-25,33,36-37,39-44,47H,4,8-13,16-21,26-32H2,1-3H3,(H2,58,73)(H2,59,75)(H,66,74)(H,67,76)(H,68,80)(H,69,77)(H,70,81)(H,71,78)(H,72,79)(H4,60,61,64)(H4,62,63,65)/t39-,40+,41+,42+,43+,44+,47+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research and Development Division Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperone				J Med Chem 30: 2291-4 (1987) BindingDB Entry DOI: 10.7270/Q2MG7RRN
					More data for this Ligand-Target Pair
Adenylate cyclase type 4 (Homo sapiens (Human))	BDBM50226410 (CHEMBL3142318) Show SMILES [#6]-[#6]-[#8]-c1ccc(-[#6]-[#6@@H]-2-[#7]-[#6](=O)-[#6]C([#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c3ccccc3)-[#7]-[#6]-2=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#7])=O)([#6]-2-[#6]-[#6]-[#6]-[#6]-2)[#6]-2-[#6]-[#6]-[#6]-[#6]-2)cc1 |r| Show InChI InChI=1S/C57H87N15O10S2/c1-4-82-38-24-22-35(23-25-38)29-41-50(77)69-42(28-34-14-6-5-7-15-34)52(79)72-47(33(2)3)54(81)70-43(30-45(58)73)51(78)71-44(32-83-84-57(31-46(74)66-41,36-16-8-9-17-36)37-18-10-11-19-37)53(80)68-40(21-13-27-65-56(62)63)49(76)67-39(48(59)75)20-12-26-64-55(60)61/h5-7,14-15,22-25,33,36-37,39-44,47H,4,8-13,16-21,26-32H2,1-3H3,(H2,58,73)(H2,59,75)(H,66,74)(H,67,76)(H,68,80)(H,69,77)(H,70,81)(H,71,78)(H,72,79)(H4,60,61,64)(H4,62,63,65)/t39-,40-,41-,42-,43-,44-,47-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research and Development Division Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperone				J Med Chem 30: 2291-4 (1987) BindingDB Entry DOI: 10.7270/Q2MG7RRN
					More data for this Ligand-Target Pair
Adenylate cyclase type 4 (Homo sapiens (Human))	BDBM50226411 (CHEMBL3142329) Show SMILES [#6]-[#6]-[#8]-c1ccc(-[#6]-[#6@@H]-2-[#7]-[#6](=O)-[#6]C([#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c3ccccc3)-[#7]-[#6]-2=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#7])=O)([#6]-2-[#6]-[#6]-[#6]-[#6]-2)[#6]-2-[#6]-[#6]-[#6]-[#6]-2)cc1 Show InChI InChI=1S/C57H87N15O10S2/c1-4-82-38-24-22-35(23-25-38)29-41-50(77)69-42(28-34-14-6-5-7-15-34)52(79)72-47(33(2)3)54(81)70-43(30-45(58)73)51(78)71-44(32-83-84-57(31-46(74)66-41,36-16-8-9-17-36)37-18-10-11-19-37)53(80)68-40(21-13-27-65-56(62)63)49(76)67-39(48(59)75)20-12-26-64-55(60)61/h5-7,14-15,22-25,33,36-37,39-44,47H,4,8-13,16-21,26-32H2,1-3H3,(H2,58,73)(H2,59,75)(H,66,74)(H,67,76)(H,68,80)(H,69,77)(H,70,81)(H,71,78)(H,72,79)(H4,60,61,64)(H4,62,63,65)/t39-,40+,41-,42-,43-,44-,47-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research and Development Division Curated by ChEMBL					Assay Description Binding affinity against sigma receptor				J Med Chem 30: 2291-4 (1987) BindingDB Entry DOI: 10.7270/Q2MG7RRN
					More data for this Ligand-Target Pair
Adenylate cyclase type 2 (Rattus norvegicus)	BDBM81778 (CAS_132421 | NNC-756 | NSC_132421) Show SMILES CN1CCc2cc(Cl)c(O)cc2C(C1)c1cccc2CCOc12 Show InChI InChI=1S/C19H20ClNO2/c1-21-7-5-13-9-17(20)18(22)10-15(13)16(11-21)14-4-2-3-12-6-8-23-19(12)14/h2-4,9-10,16,22H,5-8,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Curated by PDSP Ki Database									Eur J Pharmacol 219: 45-52 (1992) Article DOI: 10.1016/0014-2999(92)90578-r BindingDB Entry DOI: 10.7270/Q2H70D9P
					More data for this Ligand-Target Pair
Adenylate cyclase type 4 (Homo sapiens (Human))	BDBM50226417 (CHEMBL3142331) Show SMILES [#6]-[#6]-[#8]-c1ccc(-[#6]-[#6@@H]-2-[#7]-[#6](=O)-[#6]C([#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c3ccccc3)-[#7]-[#6]-2=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#7])=O)([#6]-2-[#6]-[#6]-[#6]-[#6]-2)[#6]-2-[#6]-[#6]-[#6]-[#6]-2)cc1 |r| Show InChI InChI=1S/C51H75N11O9S2/c1-4-71-35-22-20-32(21-23-35)26-37-45(66)59-38(25-31-13-6-5-7-14-31)47(68)62-43(30(2)3)49(70)60-39(27-41(52)63)46(67)61-40(48(69)58-36(44(53)65)19-12-24-56-50(54)55)29-72-73-51(28-42(64)57-37,33-15-8-9-16-33)34-17-10-11-18-34/h5-7,13-14,20-23,30,33-34,36-40,43H,4,8-12,15-19,24-29H2,1-3H3,(H2,52,63)(H2,53,65)(H,57,64)(H,58,69)(H,59,66)(H,60,70)(H,61,67)(H,62,68)(H4,54,55,56)/t36-,37-,38-,39-,40-,43-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research and Development Division Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperone				J Med Chem 30: 2291-4 (1987) BindingDB Entry DOI: 10.7270/Q2MG7RRN
					More data for this Ligand-Target Pair
Adenylate cyclase type 4 (Homo sapiens (Human))	BDBM50226413 (CHEMBL2369777) Show SMILES [#6]-[#6]-[#8]-c1ccc(-[#6]-[#6@H]-2-[#7]-[#6](=O)-[#6]C([#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c3ccccc3)-[#7]-[#6]-2=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#7])=O)([#6]-2-[#6]-[#6]-[#6]-[#6]-2)[#6]-2-[#6]-[#6]-[#6]-[#6]-2)cc1 |r| Show InChI InChI=1S/C57H87N13O10S2/c1-4-80-39-25-23-36(24-26-39)30-42-51(75)67-43(29-35-15-6-5-7-16-35)53(77)70-48(34(2)3)55(79)68-44(31-46(59)71)52(76)69-45(33-81-82-57(32-47(72)64-42,37-17-8-9-18-37)38-19-10-11-20-38)54(78)66-41(22-14-28-63-56(61)62)50(74)65-40(49(60)73)21-12-13-27-58/h5-7,15-16,23-26,34,37-38,40-45,48H,4,8-14,17-22,27-33,58H2,1-3H3,(H2,59,71)(H2,60,73)(H,64,72)(H,65,74)(H,66,78)(H,67,75)(H,68,79)(H,69,76)(H,70,77)(H4,61,62,63)/t40-,41-,42+,43-,44-,45-,48-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research and Development Division Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperone				J Med Chem 30: 2291-4 (1987) BindingDB Entry DOI: 10.7270/Q2MG7RRN
					More data for this Ligand-Target Pair
Adenylate cyclase type 2 (Rattus norvegicus)	BDBM50010709 (5-Benzofuran-7-yl-8-chloro-3-methyl-2,3,4,5-tetrah...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1cccc2ccoc12 Show InChI InChI=1S/C19H18ClNO2/c1-21-7-5-13-9-17(20)18(22)10-15(13)16(11-21)14-4-2-3-12-6-8-23-19(12)14/h2-4,6,8-10,16,22H,5,7,11H2,1H3/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Curated by PDSP Ki Database									Eur J Pharmacol 219: 45-52 (1992) Article DOI: 10.1016/0014-2999(92)90578-r BindingDB Entry DOI: 10.7270/Q2H70D9P
					More data for this Ligand-Target Pair
Adenylate cyclase type 4 (Homo sapiens (Human))	BDBM50226416 (CHEMBL2369525) Show SMILES [#6]-[#6]-[#8]-c1ccc(-[#6]-[#6@H]-2-[#7]-[#6](=O)-[#6]C([#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c3ccccc3)-[#7]-[#6]-2=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-2-[#6]-[#6]-[#6]-[#6@H]-2-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#7])=O)([#6]-2-[#6]-[#6]-[#6]-[#6]-2)[#6]-2-[#6]-[#6]-[#6]-[#6]-2)cc1 Show InChI InChI=1S/C56H82N12O10S2/c1-4-78-38-24-22-35(23-25-38)29-40-49(72)64-41(28-34-14-6-5-7-15-34)51(74)67-47(33(2)3)53(76)65-42(30-45(57)69)50(73)66-43(32-79-80-56(31-46(70)62-40,36-16-8-9-17-36)37-18-10-11-19-37)54(77)68-27-13-21-44(68)52(75)63-39(48(58)71)20-12-26-61-55(59)60/h5-7,14-15,22-25,33,36-37,39-44,47H,4,8-13,16-21,26-32H2,1-3H3,(H2,57,69)(H2,58,71)(H,62,70)(H,63,75)(H,64,72)(H,65,76)(H,66,73)(H,67,74)(H4,59,60,61)/t39-,40+,41-,42-,43-,44-,47-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research and Development Division Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperone				J Med Chem 30: 2291-4 (1987) BindingDB Entry DOI: 10.7270/Q2MG7RRN
					More data for this Ligand-Target Pair
Adenylate cyclase type 4 (Homo sapiens (Human))	BDBM50226414 (CHEMBL2369778) Show SMILES [#6]-[#6]-[#8]-c1ccc(-[#6]-[#6@H]-2-[#7]-[#6](=O)-[#6]C([#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c3ccccc3)-[#7]-[#6]-2=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#7])=O)([#6]-2-[#6]-[#6]-[#6]-[#6]-2)[#6]-2-[#6]-[#6]-[#6]-[#6]-2)cc1 |r| Show InChI InChI=1S/C57H87N13O10S2/c1-4-80-39-25-23-36(24-26-39)30-42-51(75)67-43(29-35-15-6-5-7-16-35)53(77)70-48(34(2)3)55(79)68-44(31-46(59)71)52(76)69-45(33-81-82-57(32-47(72)64-42,37-17-8-9-18-37)38-19-10-11-20-38)54(78)66-41(21-12-13-27-58)50(74)65-40(49(60)73)22-14-28-63-56(61)62/h5-7,15-16,23-26,34,37-38,40-45,48H,4,8-14,17-22,27-33,58H2,1-3H3,(H2,59,71)(H2,60,73)(H,64,72)(H,65,74)(H,66,78)(H,67,75)(H,68,79)(H,69,76)(H,70,77)(H4,61,62,63)/t40-,41-,42+,43-,44-,45-,48-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research and Development Division Curated by ChEMBL					Assay Description Binding affinity against sigma receptor				J Med Chem 30: 2291-4 (1987) BindingDB Entry DOI: 10.7270/Q2MG7RRN
					More data for this Ligand-Target Pair
Adenylate cyclase type 4 (Homo sapiens (Human))	BDBM50226418 (CHEMBL3142313) Show SMILES [#6]-[#6]-[#8]-c1ccc(-[#6]-[#6@@H]-2-[#7]-[#6](=O)-[#6]C([#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c3ccccc3)-[#7]-[#6]-2=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](-[#8])=O)([#6]-2-[#6]-[#6]-[#6]-[#6]-2)[#6]-2-[#6]-[#6]-[#6]-[#6]-2)cc1 |r| Show InChI InChI=1S/C57H86N14O11S2/c1-4-82-38-24-22-35(23-25-38)29-41-49(75)68-42(28-34-14-6-5-7-15-34)51(77)71-47(33(2)3)53(79)69-43(30-45(58)72)50(76)70-44(32-83-84-57(31-46(73)65-41,36-16-8-9-17-36)37-18-10-11-19-37)52(78)66-39(20-12-26-63-55(59)60)48(74)67-40(54(80)81)21-13-27-64-56(61)62/h5-7,14-15,22-25,33,36-37,39-44,47H,4,8-13,16-21,26-32H2,1-3H3,(H2,58,72)(H,65,73)(H,66,78)(H,67,74)(H,68,75)(H,69,79)(H,70,76)(H,71,77)(H,80,81)(H4,59,60,63)(H4,61,62,64)/t39-,40-,41-,42-,43-,44-,47-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research and Development Division Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperone				J Med Chem 30: 2291-4 (1987) BindingDB Entry DOI: 10.7270/Q2MG7RRN
					More data for this Ligand-Target Pair
Adenylate cyclase type 2 (Rattus norvegicus)	BDBM81779 (CAS_164252 | NNC-687 | NSC_164252) Show SMILES CN1CCc2cc(c(O)cc2C(C1)c1cccc2CCOc12)[N+]([O-])=O Show InChI InChI=1S/C19H20N2O4/c1-20-7-5-13-9-17(21(23)24)18(22)10-15(13)16(11-20)14-4-2-3-12-6-8-25-19(12)14/h2-4,9-10,16,22H,5-8,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Curated by PDSP Ki Database									Eur J Pharmacol 219: 45-52 (1992) Article DOI: 10.1016/0014-2999(92)90578-r BindingDB Entry DOI: 10.7270/Q2H70D9P
					More data for this Ligand-Target Pair
Adenylate cyclase type 2 (Rattus norvegicus)	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	39.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Curated by PDSP Ki Database									Eur J Pharmacol 219: 45-52 (1992) Article DOI: 10.1016/0014-2999(92)90578-r BindingDB Entry DOI: 10.7270/Q2H70D9P
					More data for this Ligand-Target Pair
Adenylate cyclase type 2 (Rattus norvegicus)	BDBM50004822 ((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...) Show SMILES Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O Show InChI InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	415	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Curated by PDSP Ki Database									Eur J Pharmacol 219: 45-52 (1992) Article DOI: 10.1016/0014-2999(92)90578-r BindingDB Entry DOI: 10.7270/Q2H70D9P
					More data for this Ligand-Target Pair
Adenylate cyclase type 9 (Homo sapiens (Human))	BDBM50049750 ((S)-3-(azetidin-2-ylmethoxy)pyridine | 3-((S)-1-Az...) Show SMILES C(Oc1cccnc1)[C@@H]1CCN1 |r| Show InChI InChI=1S/C9H12N2O/c1-2-9(6-10-4-1)12-7-8-3-5-11-8/h1-2,4,6,8,11H,3,5,7H2/t8-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									Neuropharmacology 35: 725-34 (1996) Article DOI: 10.1016/0028-3908(96)84644-2 BindingDB Entry DOI: 10.7270/Q237777N
					More data for this Ligand-Target Pair
Adenylate cyclase type 9 (Homo sapiens (Human))	BDBM50035398 ((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...) Show SMILES CN1CCC[C@H]1c1cc(C)no1 |r| Show InChI InChI=1S/C9H14N2O/c1-7-6-9(12-10-7)8-4-3-5-11(8)2/h6,8H,3-5H2,1-2H3/t8-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by PDSP Ki Database									J Pharmacol Exp Ther 270: 310-8 (1994) BindingDB Entry DOI: 10.7270/Q2HH6HKJ
					More data for this Ligand-Target Pair
Adenylate cyclase type 2 (Homo sapiens (Human))	BDBM50551445 (CHEMBL4782169) Show SMILES [H][C@@]12[C@H](O)[C@H](OC(C)=O)[C@@]3(C)C[C@](C)(CC(=O)[C@]3(O)C1[C@@H](O)CCC2(C)C)C=C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at recombinant human AC2 expressed in HEK293 cells assessed as increase in cAMP level measured after 30 mins by LANCE Ultra cAMP Det...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112115 BindingDB Entry DOI: 10.7270/Q27D2ZR4
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50010686 ((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...) Show SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Tested for effective dose agonist activity against adenylate cyclase in rat striatal membrane				J Med Chem 37: 2453-60 (1994) BindingDB Entry DOI: 10.7270/Q2KS6QKD
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50010686 ((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...) Show SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effective concentration of the compound against adenylate cyclase				J Med Chem 37: 2453-60 (1994) BindingDB Entry DOI: 10.7270/Q2KS6QKD
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50032523 ((6aR,12bS)-4-Methyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES Cc1cccc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc12 Show InChI InChI=1S/C18H19NO2/c1-10-3-2-4-12-14(10)9-19-15-6-5-11-7-16(20)17(21)8-13(11)18(12)15/h2-4,7-8,15,18-21H,5-6,9H2,1H3/t15-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	151	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effective concentration of the compound as Adenylate cyclase activity was measured in rat homogenate				J Med Chem 38: 3062-70 (1995) BindingDB Entry DOI: 10.7270/Q2JD4VTB
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50032520 ((6aR,12bS)-3-Methyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES Cc1ccc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc2c1 Show InChI InChI=1S/C18H19NO2/c1-10-2-4-13-12(6-10)9-19-15-5-3-11-7-16(20)17(21)8-14(11)18(13)15/h2,4,6-8,15,18-21H,3,5,9H2,1H3/t15-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	134	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effective concentration of the compound as Adenylate cyclase activity was measured in rat homogenate				J Med Chem 38: 3062-70 (1995) BindingDB Entry DOI: 10.7270/Q2JD4VTB
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50010686 ((6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydr...) Show SMILES Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O Show InChI InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	141	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effective concentration of the compound as Adenylate cyclase activity was measured in rat homogenate				J Med Chem 38: 3062-70 (1995) BindingDB Entry DOI: 10.7270/Q2JD4VTB
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50010684 ((6aR,12bS)-6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES CCCN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 Show InChI InChI=1S/C20H23NO2/c1-2-9-21-12-14-5-3-4-6-15(14)20-16-11-19(23)18(22)10-13(16)7-8-17(20)21/h3-6,10-11,17,20,22-23H,2,7-9,12H2,1H3/t17-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>10	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effective concentration of the compound as Adenylate cyclase activity was measured in rat homogenate				J Med Chem 38: 3062-70 (1995) BindingDB Entry DOI: 10.7270/Q2JD4VTB
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50032517 ((6aR,12bS)-2-Ethyl-5,6,6a,7,8,12b-hexahydro-benzo[...) Show SMILES CCc1ccc2CN[C@@H]3CCc4cc(O)c(O)cc4[C@H]3c2c1 Show InChI InChI=1S/C19H21NO2/c1-2-11-3-4-13-10-20-16-6-5-12-8-17(21)18(22)9-15(12)19(16)14(13)7-11/h3-4,7-9,16,19-22H,2,5-6,10H2,1H3/t16-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	610	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effective concentration of the compound as Adenylate cyclase activity was measured in rat homogenate				J Med Chem 38: 3062-70 (1995) BindingDB Entry DOI: 10.7270/Q2JD4VTB
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50032519 ((6aR,12bS)-2-Phenyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES Oc1cc2CC[C@H]3NCc4ccc(cc4[C@@H]3c2cc1O)-c1ccccc1 Show InChI InChI=1S/C23H21NO2/c25-21-11-16-8-9-20-23(19(16)12-22(21)26)18-10-15(6-7-17(18)13-24-20)14-4-2-1-3-5-14/h1-7,10-12,20,23-26H,8-9,13H2/t20-,23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effective concentration of the compound as Adenylate cyclase activity was measured in rat homogenate				J Med Chem 38: 3062-70 (1995) BindingDB Entry DOI: 10.7270/Q2JD4VTB
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50032516 ((6aR,12bS)-4-Methyl-6-propyl-5,6,6a,7,8,12b-hexahy...) Show SMILES CCCN1Cc2c(C)cccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 Show InChI InChI=1S/C21H25NO2/c1-3-9-22-12-17-13(2)5-4-6-15(17)21-16-11-20(24)19(23)10-14(16)7-8-18(21)22/h4-6,10-11,18,21,23-24H,3,7-9,12H2,1-2H3/t18-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	333	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effective concentration of the compound as Adenylate cyclase activity was measured in rat homogenate				J Med Chem 38: 3062-70 (1995) BindingDB Entry DOI: 10.7270/Q2JD4VTB
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50032521 ((6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenan...) Show SMILES Oc1ccc2CN[C@@H]3CCc4cc(O)c(O)cc4[C@H]3c2c1 Show InChI InChI=1S/C17H17NO3/c19-11-3-1-10-8-18-14-4-2-9-5-15(20)16(21)7-13(9)17(14)12(10)6-11/h1,3,5-7,14,17-21H,2,4,8H2/t14-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	148	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effective concentration of the compound as Adenylate cyclase activity was measured in rat homogenate				J Med Chem 38: 3062-70 (1995) BindingDB Entry DOI: 10.7270/Q2JD4VTB
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50032522 ((6aR,12bS)-2-Methyl-5,6,6a,7,8,12b-hexahydro-benzo...) Show SMILES Cc1ccc2CN[C@@H]3CCc4cc(O)c(O)cc4[C@H]3c2c1 Show InChI InChI=1S/C18H19NO2/c1-10-2-3-12-9-19-15-5-4-11-7-16(20)17(21)8-14(11)18(15)13(12)6-10/h2-3,6-8,15,18-21H,4-5,9H2,1H3/t15-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	114	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effective concentration of the compound as Adenylate cyclase activity was measured in rat homogenate				J Med Chem 38: 3062-70 (1995) BindingDB Entry DOI: 10.7270/Q2JD4VTB
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50032524 ((6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenan...) Show SMILES Oc1ccc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc2c1 Show InChI InChI=1S/C17H17NO3/c19-11-2-3-12-10(5-11)8-18-14-4-1-9-6-15(20)16(21)7-13(9)17(12)14/h2-3,5-7,14,17-21H,1,4,8H2/t14-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effective concentration of the compound as Adenylate cyclase activity was measured in rat homogenate				J Med Chem 38: 3062-70 (1995) BindingDB Entry DOI: 10.7270/Q2JD4VTB
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50032518 ((6aR,12bS)-3-Methyl-6-propyl-5,6,6a,7,8,12b-hexahy...) Show SMILES CCCN1Cc2cc(C)ccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 Show InChI InChI=1S/C21H25NO2/c1-3-8-22-12-15-9-13(2)4-6-16(15)21-17-11-20(24)19(23)10-14(17)5-7-18(21)22/h4,6,9-11,18,21,23-24H,3,5,7-8,12H2,1-2H3/t18-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effective concentration of the compound as Adenylate cyclase activity was measured in rat homogenate				J Med Chem 38: 3062-70 (1995) BindingDB Entry DOI: 10.7270/Q2JD4VTB
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50009864 (CHEMBL274833 | [2-Methyl-1-(2-morpholin-4-yl-ethyl...) Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2ccccc2n1CCN1CCOCC1 Show InChI InChI=1S/C26H26N2O2/c1-19-25(26(29)22-11-6-8-20-7-2-3-9-21(20)22)23-10-4-5-12-24(23)28(19)14-13-27-15-17-30-18-16-27/h2-12H,13-18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of hormone stimulated Adenylate cyclase activity in N18TG2 membranes.				J Med Chem 39: 1967-74 (1996) Article DOI: 10.1021/jm950932r BindingDB Entry DOI: 10.7270/Q27M071B
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50009854 (CHEMBL13078 | [1-(2-Morpholin-4-yl-ethyl)-1H-indol...) Show SMILES O=C(c1cn(CCN2CCOCC2)c2ccccc12)c1cccc2ccccc12 Show InChI InChI=1S/C25H24N2O2/c28-25(22-10-5-7-19-6-1-2-8-20(19)22)23-18-27(24-11-4-3-9-21(23)24)13-12-26-14-16-29-17-15-26/h1-11,18H,12-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	275	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of hormone stimulated Adenylate cyclase activity in N18TG2 membranes.				J Med Chem 39: 1967-74 (1996) Article DOI: 10.1021/jm950932r BindingDB Entry DOI: 10.7270/Q27M071B
					More data for this Ligand-Target Pair
Adenylate cyclase type 5 (Rattus norvegicus)	BDBM50050489 (CHEMBL61448 | [6-Isothiocyanato-1-(2-morpholin-4-y...) Show SMILES O=C(c1cn(CCN2CCOCC2)c2cc(ccc12)N=C=S)c1cccc2ccccc12 Show InChI InChI=1S/C26H23N3O2S/c30-26(23-7-3-5-19-4-1-2-6-21(19)23)24-17-29(11-10-28-12-14-31-15-13-28)25-16-20(27-18-32)8-9-22(24)25/h1-9,16-17H,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of hormone stimulated Adenylate cyclase activity in N18TG2 membranes.				J Med Chem 39: 1967-74 (1996) Article DOI: 10.1021/jm950932r BindingDB Entry DOI: 10.7270/Q27M071B
					More data for this Ligand-Target Pair

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