Compile Data Set for Download or QSAR

Found 445 hits Enz. Inhib. hit(s) with Target = 'Alpha-synuclein'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM481157 (US10906900, Reference 25a) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1cccs1 Show InChI InChI=1S/C21H17N3S/c1-24(2)18-10-6-15(7-11-18)5-9-17-14-16-8-12-19(23-21(16)22-17)20-4-3-13-25-20/h3-4,6-8,10-14H,1-2H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481157 (US10906900, Reference 25a) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1cccs1 Show InChI InChI=1S/C21H17N3S/c1-24(2)18-10-6-15(7-11-18)5-9-17-14-16-8-12-19(23-21(16)22-17)20-4-3-13-25-20/h3-4,6-8,10-14H,1-2H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481149 (US10906900, Reference 22a) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2cccnc2[nH]1 Show InChI InChI=1S/C17H15N3/c1-20(2)16-9-6-13(7-10-16)5-8-15-12-14-4-3-11-18-17(14)19-15/h3-4,6-7,9-12H,1-2H3,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481149 (US10906900, Reference 22a) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2cccnc2[nH]1 Show InChI InChI=1S/C17H15N3/c1-20(2)16-9-6-13(7-10-16)5-8-15-12-14-4-3-11-18-17(14)19-15/h3-4,6-7,9-12H,1-2H3,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481158 (US10906900, Reference 25b) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1ccsc1 Show InChI InChI=1S/C21H17N3S/c1-24(2)19-8-4-15(5-9-19)3-7-18-13-16-6-10-20(23-21(16)22-18)17-11-12-25-14-17/h4-6,8-14H,1-2H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481153 (US10906900, Reference 22f) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(F)nc2[nH]1 Show InChI InChI=1S/C17H14FN3/c1-21(2)15-8-4-12(5-9-15)3-7-14-11-13-6-10-16(18)20-17(13)19-14/h4-6,8-11H,1-2H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481156 (US10906900, Reference 22d) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2cnccc2[nH]1 Show InChI InChI=1S/C17H15N3/c1-20(2)16-7-4-13(5-8-16)3-6-15-11-14-12-18-10-9-17(14)19-15/h4-5,7-12,19H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481156 (US10906900, Reference 22d) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2cnccc2[nH]1 Show InChI InChI=1S/C17H15N3/c1-20(2)16-7-4-13(5-8-16)3-6-15-11-14-12-18-10-9-17(14)19-15/h4-5,7-12,19H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50545096 (CHEMBL4637732) Show SMILES [O-][N+](=O)c1ccc(F)cc1CN(Cc1ccco1)C(=O)\C=C\c1ccc(F)cc1 Show InChI InChI=1S/C21H16F2N2O4/c22-17-6-3-15(4-7-17)5-10-21(26)24(14-19-2-1-11-29-19)13-16-12-18(23)8-9-20(16)25(27)28/h1-12H,13-14H2/b10-5+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Binding affinity to human wlid-type alpha-synuclein by SPR analysis				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115358 BindingDB Entry DOI: 10.7270/Q2X92FWW
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481159 (US10906900, Reference 25c) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1ccc(F)nc1 Show InChI InChI=1S/C22H17FN4/c1-27(2)19-9-4-15(5-10-19)3-8-18-13-16-6-11-20(26-22(16)25-18)17-7-12-21(23)24-14-17/h4-7,9-14H,1-2H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.27	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481150 (US10906900, Reference 22b) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccncc2[nH]1 Show InChI InChI=1S/C17H15N3/c1-20(2)16-7-4-13(5-8-16)3-6-15-11-14-9-10-18-12-17(14)19-15/h4-5,7-12,19H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481150 (US10906900, Reference 22b) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccncc2[nH]1 Show InChI InChI=1S/C17H15N3/c1-20(2)16-7-4-13(5-8-16)3-6-15-11-14-9-10-18-12-17(14)19-15/h4-5,7-12,19H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481160 (US10906900, Reference 28) Show SMILES CN(CCF)c1ccc(cc1)C#Cc1cc2cccnc2[nH]1 Show InChI InChI=1S/C18H16FN3/c1-22(12-10-19)17-8-5-14(6-9-17)4-7-16-13-15-3-2-11-20-18(15)21-16/h2-3,5-6,8-9,11,13H,10,12H2,1H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481160 (US10906900, Reference 28) Show SMILES CN(CCF)c1ccc(cc1)C#Cc1cc2cccnc2[nH]1 Show InChI InChI=1S/C18H16FN3/c1-22(12-10-19)17-8-5-14(6-9-17)4-7-16-13-15-3-2-11-20-18(15)21-16/h2-3,5-6,8-9,11,13H,10,12H2,1H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481151 (US10906900, Reference 22c) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ncccc2[nH]1 Show InChI InChI=1S/C17H15N3/c1-20(2)15-9-6-13(7-10-15)5-8-14-12-17-16(19-14)4-3-11-18-17/h3-4,6-7,9-12,19H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	3.25	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM481151 (US10906900, Reference 22c) Show SMILES CN(C)c1ccc(cc1)C#Cc1cc2ncccc2[nH]1 Show InChI InChI=1S/C17H15N3/c1-20(2)15-9-6-13(7-10-15)5-8-14-12-17-16(19-14)4-3-11-18-17/h3-4,6-7,9-12,19H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	3.25	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50614060 (CHEMBL5270314) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50545088 (CHEMBL4633757) Show SMILES [O-][N+](=O)c1ccccc1CN(Cc1ccco1)C(=O)\C=C\c1ccc(cc1)C#N Show InChI InChI=1S/C22H17N3O4/c23-14-18-9-7-17(8-10-18)11-12-22(26)24(16-20-5-3-13-29-20)15-19-4-1-2-6-21(19)25(27)28/h1-13H,15-16H2/b12-11+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Binding affinity to human wlid-type alpha-synuclein by SPR analysis				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115358 BindingDB Entry DOI: 10.7270/Q2X92FWW
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50103964 (CHEMBL3593932) Show SMILES [O-][N+](=O)c1ccc(\C=C\C=C2/C(=O)N(Cc3ccc(OCCF)cc3)c3ccccc23)cc1 Show InChI InChI=1S/C26H21FN2O4/c27-16-17-33-22-14-10-20(11-15-22)18-28-25-7-2-1-5-23(25)24(26(28)30)6-3-4-19-8-12-21(13-9-19)29(31)32/h1-15H,16-18H2/b4-3+,24-6-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a
Washington University School of Medicine Curated by ChEMBL					Assay Description Binding affinity to recombinant alpha-synuclein (unknown origin) expressed in Escherichia coli after 1 hr by scintillation counting				J Med Chem 58: 6002-17 (2015) Article DOI: 10.1021/acs.jmedchem.5b00571 BindingDB Entry DOI: 10.7270/Q24Q7WRC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50582842 (CHEMBL5087695) Show SMILES [O-][N+](=O)c1ccc(\C=C\c2ccccc2NC(=O)c2ccccn2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113887 BindingDB Entry DOI: 10.7270/Q2FX7FBG
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50545097 (CHEMBL4634055) Show SMILES [O-][N+](=O)c1ccc(F)cc1CN(Cc1ccccc1)C(=O)\C=C\c1ccc(F)cc1 Show InChI InChI=1S/C23H18F2N2O3/c24-20-9-6-17(7-10-20)8-13-23(28)26(15-18-4-2-1-3-5-18)16-19-14-21(25)11-12-22(19)27(29)30/h1-14H,15-16H2/b13-8+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Binding affinity to human wlid-type alpha-synuclein by SPR analysis				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115358 BindingDB Entry DOI: 10.7270/Q2X92FWW
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50185987 (2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...) Show SMILES [#6]-[#7](-[#6]-[#6]F)-c1ccc2cc(ccc2c1)-[#6](\[#6])=[#6](\C#N)C#N Show InChI InChI=1S/C18H16FN3/c1-13(17(11-20)12-21)14-3-4-16-10-18(22(2)8-7-19)6-5-15(16)9-14/h3-6,9-10H,7-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	16.1	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50185987 (2-(1-(6-((2-fluoroethyl)(methyl)amino)naphthalen-2...) Show SMILES [#6]-[#7](-[#6]-[#6]F)-c1ccc2cc(ccc2c1)-[#6](\[#6])=[#6](\C#N)C#N Show InChI InChI=1S/C18H16FN3/c1-13(17(11-20)12-21)14-3-4-16-10-18(22(2)8-7-19)6-5-15(16)9-14/h3-6,9-10H,7-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	16.1	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50492518 (Florbetapir | US10906900, AV45) Show SMILES CNc1ccc(\C=C\c2ccc(OCCOCCOCCF)nc2)cc1 Show InChI InChI=1S/C20H25FN2O3/c1-22-19-7-4-17(5-8-19)2-3-18-6-9-20(23-16-18)26-15-14-25-13-12-24-11-10-21/h2-9,16,22H,10-15H2,1H3/b3-2+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	24.3	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50492518 (Florbetapir | US10906900, AV45) Show SMILES CNc1ccc(\C=C\c2ccc(OCCOCCOCCF)nc2)cc1 Show InChI InChI=1S/C20H25FN2O3/c1-22-19-7-4-17(5-8-19)2-3-18-6-9-20(23-16-18)26-15-14-25-13-12-24-11-10-21/h2-9,16,22H,10-15H2,1H3/b3-2+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	24.3	n/a	n/a	n/a	n/a	n/a
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE D''ORLEANS; UNIVERSITE DE TOURS; CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS; INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) US Patent					Assay Description Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...				US Patent US10906900 (2021) BindingDB Entry DOI: 10.7270/Q2BC42NC
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50614041 (CHEMBL5286480) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50614041 (CHEMBL5286480) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50609392 (CHEMBL5276896) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50582831 (CHEMBL5074716) Show SMILES COc1ccc(\C=C\c2ccccc2NC(=O)c2ccccc2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113887 BindingDB Entry DOI: 10.7270/Q2FX7FBG
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50614044 (CHEMBL5283353) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50545098 (CHEMBL4644640) Show SMILES [O-][N+](=O)c1ccccc1CN(Cc1ccccc1)C(=O)\C=C\c1ccc(F)cc1 Show InChI InChI=1S/C23H19FN2O3/c24-21-13-10-18(11-14-21)12-15-23(27)25(16-19-6-2-1-3-7-19)17-20-8-4-5-9-22(20)26(28)29/h1-15H,16-17H2/b15-12+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Binding affinity to human wlid-type alpha-synuclein by SPR analysis				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115358 BindingDB Entry DOI: 10.7270/Q2X92FWW
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50389294 (CHEMBL2063787) Show SMILES COc1ccc2Nc3ccc(cc3Sc2c1)[N+]([O-])=O Show InChI InChI=1S/C13H10N2O3S/c1-18-9-3-5-11-13(7-9)19-12-6-8(15(16)17)2-4-10(12)14-11/h2-7,14H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113887 BindingDB Entry DOI: 10.7270/Q2FX7FBG
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50610486 (CHEMBL5290387) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50582846 (CHEMBL5088083) Show SMILES COc1ccc(\C=C\c2ccccc2NC(=O)c2ccccn2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113887 BindingDB Entry DOI: 10.7270/Q2FX7FBG
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50582840 (CHEMBL5092684) Show SMILES CN(C)c1ccc(\C=C\c2ccccc2NC(=O)c2ccccn2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113887 BindingDB Entry DOI: 10.7270/Q2FX7FBG
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50545087 (CHEMBL4639644) Show SMILES [O-][N+](=O)c1ccccc1CN(Cc1ccccc1)C(=O)\C=C\c1ccc(cc1)C#N Show InChI InChI=1S/C24H19N3O3/c25-16-20-12-10-19(11-13-20)14-15-24(28)26(17-21-6-2-1-3-7-21)18-22-8-4-5-9-23(22)27(29)30/h1-15H,17-18H2/b15-14+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Binding affinity to human wlid-type alpha-synuclein by SPR analysis				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115358 BindingDB Entry DOI: 10.7270/Q2X92FWW
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50545092 (CHEMBL4642469) Show SMILES O=C(\C=C\c1ccc(cc1)C#N)N(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C24H20N2O/c25-17-21-13-11-20(12-14-21)15-16-24(27)26(18-22-7-3-1-4-8-22)19-23-9-5-2-6-10-23/h1-16H,18-19H2/b16-15+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Binding affinity to human wlid-type alpha-synuclein by SPR analysis				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115358 BindingDB Entry DOI: 10.7270/Q2X92FWW
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50545086 (CHEMBL4648610) Show SMILES COc1ccccc1N(Cc1ccccc1[N+]([O-])=O)C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C23H20N2O4/c1-29-22-14-8-7-13-21(22)24(17-19-11-5-6-12-20(19)25(27)28)23(26)16-15-18-9-3-2-4-10-18/h2-16H,17H2,1H3/b16-15+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Binding affinity to human wlid-type alpha-synuclein by SPR analysis				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115358 BindingDB Entry DOI: 10.7270/Q2X92FWW
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50545090 (CHEMBL4634968) Show SMILES [O-][N+](=O)c1ccccc1CN(CCc1ccccc1)C(=O)\C=C\c1ccc(cc1)C#N Show InChI InChI=1S/C25H21N3O3/c26-18-22-12-10-21(11-13-22)14-15-25(29)27(17-16-20-6-2-1-3-7-20)19-23-8-4-5-9-24(23)28(30)31/h1-15H,16-17,19H2/b15-14+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Binding affinity to human wlid-type alpha-synuclein by SPR analysis				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115358 BindingDB Entry DOI: 10.7270/Q2X92FWW
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50582841 (CHEMBL5075163) Show SMILES [O-][N+](=O)c1ccc(\C=C\c2ccccc2NC(=O)c2ccccc2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113887 BindingDB Entry DOI: 10.7270/Q2FX7FBG
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50582834 (CHEMBL5086296) Show SMILES CN(C)c1ccc(\C=C\c2ccccc2NC(=O)c2cccnn2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113887 BindingDB Entry DOI: 10.7270/Q2FX7FBG
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50582839 (CHEMBL5072207) Show SMILES CN(C)c1ccc(\C=C\c2ccccc2NC(=O)c2ccccc2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113887 BindingDB Entry DOI: 10.7270/Q2FX7FBG
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50553261 (CHEMBL4763384) Show SMILES [H][C@]12C[C@]([H])(c3ccccc13)c1cc3c(cc21)[C@]1([H])C[C@@]3([H])c2c1c(c1c(c2P(O)(O)=O)[C@@]2([H])C[C@]1([H])c1cc3c(cc21)[C@@]1([H])C[C@]3([H])c2ccccc12)P(O)(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to human alpha-synuclein (1-140 residues) expressed in Escherichia coli BL21(DE3) assessed as first dissociation constant by mass-sp...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50582827 (CHEMBL5075837) Show SMILES COc1ccc(\C=C\c2cccc(NC(=O)c3ccccc3)c2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113887 BindingDB Entry DOI: 10.7270/Q2FX7FBG
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50553260 (CHEMBL4748063) Show SMILES Brc1cccc(c1)-c1cc([nH]n1)-c1ccc2OCOc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to alpha-synuclein (unknown origin) expressed in Escherichia coli BL21(DE3) pLysS by fluorescence method				Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50582851 (CHEMBL5085623) Show SMILES COc1ccc(\C=C\c2ccccc2NC(=O)Cc2ccccc2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113887 BindingDB Entry DOI: 10.7270/Q2FX7FBG
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50582849 (CHEMBL5080710) Show SMILES COc1ccc(\C=C\c2ccccc2NC(=O)c2ccn[nH]2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113887 BindingDB Entry DOI: 10.7270/Q2FX7FBG
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50545099 (CHEMBL4647336) Show SMILES COc1ccccc1CN(Cc1cc(F)ccc1[N+]([O-])=O)C(=O)\C=C\c1ccc(F)cc1 Show InChI InChI=1S/C24H20F2N2O4/c1-32-23-5-3-2-4-18(23)15-27(16-19-14-21(26)11-12-22(19)28(30)31)24(29)13-8-17-6-9-20(25)10-7-17/h2-14H,15-16H2,1H3/b13-8+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	332	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Binding affinity to human wlid-type alpha-synuclein by SPR analysis				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115358 BindingDB Entry DOI: 10.7270/Q2X92FWW
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50545093 (CHEMBL4645133) Show SMILES CC(C)(C)NC(=O)c1ccc(\C=C\C(=O)N(Cc2ccccc2)Cc2ccccc2[N+]([O-])=O)cc1 Show InChI InChI=1S/C28H29N3O4/c1-28(2,3)29-27(33)23-16-13-21(14-17-23)15-18-26(32)30(19-22-9-5-4-6-10-22)20-24-11-7-8-12-25(24)31(34)35/h4-18H,19-20H2,1-3H3,(H,29,33)/b18-15+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	344	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Binding affinity to human wlid-type alpha-synuclein by SPR analysis				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115358 BindingDB Entry DOI: 10.7270/Q2X92FWW
					More data for this Ligand-Target Pair
Alpha-synuclein (Homo sapiens (Human))	BDBM50582844 (CHEMBL5084363) Show SMILES [O-][N+](=O)c1cccc(\C=C\c2ccccc2NC(=O)c2ccccc2)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human alpha-syn aggregates assessed as dissociation constant by SPR analysis				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113887 BindingDB Entry DOI: 10.7270/Q2FX7FBG
					More data for this Ligand-Target Pair

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