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Patent code US8871790

Compile Data Set for Download or QSAR

Found 475 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fatty acid synthase


(Homo sapiens (Human))		BDBM137038
PNG
(US8871790, 104)
Show SMILES CN1CCc2nc([nH]c2C1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C(F)(F)F)c(C)cc1C
Show InChI InChI=1S/C28H31F3N4O/c1-17-14-18(2)23(15-22(17)26-32-24-10-11-34(3)16-25(24)33-26)27(36)35-12-8-20(9-13-35)19-4-6-21(7-5-19)28(29,30)31/h4-7,14-15,20H,8-13,16H2,1-3H3,(H,32,33)
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n/an/a 130n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137043
PNG
(US8871790, 109)
Show SMILES CN(C)C(=O)c1ccc2[nH]c(nc2c1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1C
Show InChI InChI=1S/C31H31N5O2/c1-19-15-20(2)26(31(38)36-13-11-23(12-14-36)22-7-5-21(18-32)6-8-22)17-25(19)29-33-27-10-9-24(16-28(27)34-29)30(37)35(3)4/h5-10,15-17,23H,11-14H2,1-4H3,(H,33,34)
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n/an/a 250n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137057
PNG
(US8871790, 125)
Show SMILES O=C(Nc1cc(ccn1)C(=O)N1CCC(CC1)c1ccc(cc1)C#N)N1CCCC1
Show InChI InChI=1S/C23H25N5O2/c24-16-17-3-5-18(6-4-17)19-8-13-27(14-9-19)22(29)20-7-10-25-21(15-20)26-23(30)28-11-1-2-12-28/h3-7,10,15,19H,1-2,8-9,11-14H2,(H,25,26,30)
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n/an/a>5.00E+4n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137058
PNG
(US8871790, 126)
Show SMILES CC(C)Nc1ccc(cn1)C(=O)Nc1ccc(C)c(C(=O)N2CCC(F)(CC2)c2ccc(cc2)C#N)c1C
Show InChI InChI=1S/C30H32FN5O2/c1-19(2)34-26-12-8-23(18-33-26)28(37)35-25-11-5-20(3)27(21(25)4)29(38)36-15-13-30(31,14-16-36)24-9-6-22(17-32)7-10-24/h5-12,18-19H,13-16H2,1-4H3,(H,33,34)(H,35,37)
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n/an/a>5.00E+4n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137062
PNG
(US8871790, 130)
Show SMILES Cc1cc(C)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nnc(CC2CCOC2)[nH]1
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n/an/a 300n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137073
PNG
(US8871790, 141)
Show SMILES Cc1cc(C)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nnc(CC2COC2)[nH]1
Show InChI InChI=1S/C27H29N5O2/c1-17-11-18(2)24(13-23(17)26-29-25(30-31-26)12-20-15-34-16-20)27(33)32-9-7-22(8-10-32)21-5-3-19(14-28)4-6-21/h3-6,11,13,20,22H,7-10,12,15-16H2,1-2H3,(H,29,30,31)
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n/an/a>5.00E+4n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137077
PNG
(US8871790, 145)
Show SMILES Cc1cc(C2CC2)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nnc(CN2CCC2)[nH]1
Show InChI InChI=1S/C29H32N6O/c1-19-15-25(23-7-8-23)26(28-31-27(32-33-28)18-34-11-2-12-34)16-24(19)29(36)35-13-9-22(10-14-35)21-5-3-20(17-30)4-6-21/h3-6,15-16,22-23H,2,7-14,18H2,1H3,(H,31,32,33)
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n/an/a 820n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137078
PNG
(US8871790, 146)
Show SMILES CN(C)C(=O)Cc1nnc([nH]1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1C1CC1
Show InChI InChI=1S/C29H32N6O2/c1-18-14-24(22-8-9-22)25(28-31-26(32-33-28)16-27(36)34(2)3)15-23(18)29(37)35-12-10-21(11-13-35)20-6-4-19(17-30)5-7-20/h4-7,14-15,21-22H,8-13,16H2,1-3H3,(H,31,32,33)
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n/an/a 260n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137079
PNG
(US8871790, 147)
Show SMILES CCc1cc(C)c(cc1-c1nnc(CCOC)[nH]1)C(=O)N1CCC(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C27H31N5O2/c1-4-20-15-18(2)23(16-24(20)26-29-25(30-31-26)11-14-34-3)27(33)32-12-9-22(10-13-32)21-7-5-19(17-28)6-8-21/h5-8,15-16,22H,4,9-14H2,1-3H3,(H,29,30,31)
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n/an/a 250n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137085
PNG
(US8871790, 153)
Show SMILES COCCc1nnc([nH]1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1C1CCC1
Show InChI InChI=1S/C29H33N5O2/c1-19-16-25(23-4-3-5-23)26(28-31-27(32-33-28)12-15-36-2)17-24(19)29(35)34-13-10-22(11-14-34)21-8-6-20(18-30)7-9-21/h6-9,16-17,22-23H,3-5,10-15H2,1-2H3,(H,31,32,33)
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n/an/a 55n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM136952
PNG
(US8871790, 3)
Show SMILES CC(=O)N1CCc2nc([nH]c2C1)-c1cc(ccc1C)C(=O)N1CCC(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C28H29N5O2/c1-18-3-6-23(15-24(18)27-30-25-11-14-33(19(2)34)17-26(25)31-27)28(35)32-12-9-22(10-13-32)21-7-4-20(16-29)5-8-21/h3-8,15,22H,9-14,17H2,1-2H3,(H,30,31)
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n/an/a 146n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM136961
PNG
(US8871790, 13)
Show SMILES CNC(=O)C1Cc2nc([nH]c2C1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1C
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n/an/a 260n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM50426431
PNG
(CHEMBL2322362)
Show SMILES Cc1cc(C)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nc2cc(ncc2[nH]1)S(C)(=O)=O
Show InChI InChI=1S/C28H27N5O3S/c1-17-12-18(2)23(13-22(17)27-31-24-14-26(37(3,35)36)30-16-25(24)32-27)28(34)33-10-8-21(9-11-33)20-6-4-19(15-29)5-7-20/h4-7,12-14,16,21H,8-11H2,1-3H3,(H,31,32)
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n/an/a 85n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM136976
PNG
(US8871790, 40)
Show SMILES CC(C)Nc1ccc(cn1)C(=O)Nc1cc(ccc1C)C(=O)N1CCCC(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C30H33N5O2/c1-20(2)33-28-13-12-26(19-32-28)29(36)34-27-17-25(9-6-21(27)3)30(37)35-15-4-5-23(14-16-35)24-10-7-22(18-31)8-11-24/h6-13,17,19-20,23H,4-5,14-16H2,1-3H3,(H,32,33)(H,34,36)
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n/an/a 50n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM136985
PNG
(US8871790, 50)
Show SMILES CC(C)Nc1ccc(cn1)C(=O)Nc1cc(ccc1C)C(=O)N1CCC(CC1)c1ccc(cn1)C#N
Show InChI InChI=1S/C28H30N6O2/c1-18(2)32-26-9-7-23(17-31-26)27(35)33-25-14-22(6-4-19(25)3)28(36)34-12-10-21(11-13-34)24-8-5-20(15-29)16-30-24/h4-9,14,16-18,21H,10-13H2,1-3H3,(H,31,32)(H,33,35)
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n/an/a 520n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM136990
PNG
(US8871790, 55)
Show SMILES CCc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC1)C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C30H30FN5O2/c1-2-22-6-7-23(18-26(22)34-28(37)24-8-11-27(33-20-24)35-14-3-15-35)29(38)36-16-12-30(31,13-17-36)25-9-4-21(19-32)5-10-25/h4-11,18,20H,2-3,12-17H2,1H3,(H,34,37)
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n/an/a 35n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137002
PNG
(US8871790, 68)
Show SMILES CCc1cc(C)c(NC(=O)NC2CCCOC2)cc1C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C28H33FN4O3/c1-3-21-15-19(2)25(32-27(35)31-23-5-4-14-36-18-23)16-24(21)26(34)33-12-10-28(29,11-13-33)22-8-6-20(17-30)7-9-22/h6-9,15-16,23H,3-5,10-14,18H2,1-2H3,(H2,31,32,35)
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n/an/a 100n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137011
PNG
(US8871790, 77)
Show SMILES FC(F)(F)c1ccc(cc1NC(=O)NC1CCOC1)C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C25H24F4N4O3/c26-24(18-4-1-16(14-30)2-5-18)8-10-33(11-9-24)22(34)17-3-6-20(25(27,28)29)21(13-17)32-23(35)31-19-7-12-36-15-19/h1-6,13,19H,7-12,15H2,(H2,31,32,35)
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n/an/a 80n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137014
PNG
(US8871790, 80)
Show SMILES Cc1cc(C)c(cc1NC(=O)O[C@@H]1CCOC1)C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N |r|
Show InChI InChI=1S/C26H28FN3O4/c1-17-13-18(2)23(29-25(32)34-21-7-12-33-16-21)14-22(17)24(31)30-10-8-26(27,9-11-30)20-5-3-19(15-28)4-6-20/h3-6,13-14,21H,7-12,16H2,1-2H3,(H,29,32)/t21-/m1/s1
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n/an/a 400n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137117
PNG
(US8871790, 185)
Show SMILES CCc1cc(C2CCC2)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nnc(COC)[nH]1
Show InChI InChI=1S/C29H33N5O2/c1-3-20-15-24(23-5-4-6-23)26(28-31-27(18-36-2)32-33-28)16-25(20)29(35)34-13-11-22(12-14-34)21-9-7-19(17-30)8-10-21/h7-10,15-16,22-23H,3-6,11-14,18H2,1-2H3,(H,31,32,33)
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n/an/a 80n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137122
PNG
(US8871790, 190)
Show SMILES COCc1nnc([nH]1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(cc1C)C1CC1
Show InChI InChI=1S/C27H29N5O2/c1-17-13-23(21-7-8-21)24(14-22(17)26-29-25(16-34-2)30-31-26)27(33)32-11-9-20(10-12-32)19-5-3-18(15-28)4-6-19/h3-6,13-14,20-21H,7-12,16H2,1-2H3,(H,29,30,31)
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n/an/a 5.06E+3n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137123
PNG
(US8871790, 191)
Show SMILES CCc1cc(C)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nnc(CCOC)[nH]1
Show InChI InChI=1S/C27H31N5O2/c1-4-20-15-18(2)23(26-29-25(30-31-26)11-14-34-3)16-24(20)27(33)32-12-9-22(10-13-32)21-7-5-19(17-28)6-8-21/h5-8,15-16,22H,4,9-14H2,1-3H3,(H,29,30,31)
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n/an/a 200n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137124
PNG
(US8871790, 192)
Show SMILES CCc1cc(C)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nnc([nH]1)C1CCOC1
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n/an/a 300n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137144
PNG
(US8871790, 212)
Show SMILES COCCN(C)c1nnc([nH]1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1C
Show InChI InChI=1S/C27H32N6O2/c1-18-15-19(2)24(16-23(18)25-29-27(31-30-25)32(3)13-14-35-4)26(34)33-11-9-22(10-12-33)21-7-5-20(17-28)6-8-21/h5-8,15-16,22H,9-14H2,1-4H3,(H,29,30,31)
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n/an/a 7.19E+3n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137145
PNG
(US8871790, 213)
Show SMILES Cc1cc(C)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nnc([nH]1)N1CCOCC1
Show InChI InChI=1S/C27H30N6O2/c1-18-15-19(2)24(16-23(18)25-29-27(31-30-25)33-11-13-35-14-12-33)26(34)32-9-7-22(8-10-32)21-5-3-20(17-28)4-6-21/h3-6,15-16,22H,7-14H2,1-2H3,(H,29,30,31)
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n/an/a 790n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137148
PNG
(US8871790, 216)
Show SMILES CCc1cc(C2CCC2)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1nnc(OC)[nH]1
Show InChI InChI=1S/C28H31N5O2/c1-3-19-15-23(22-5-4-6-22)25(26-30-28(35-2)32-31-26)16-24(19)27(34)33-13-11-21(12-14-33)20-9-7-18(17-29)8-10-20/h7-10,15-16,21-22H,3-6,11-14H2,1-2H3,(H,30,31,32)
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n/an/a 90n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137149
PNG
(US8871790, 217)
Show SMILES CCc1cc(C2CCC2)c(cc1C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N)-c1nnc(OC)[nH]1
Show InChI InChI=1S/C28H30FN5O2/c1-3-19-15-22(20-5-4-6-20)24(25-31-27(36-2)33-32-25)16-23(19)26(35)34-13-11-28(29,12-14-34)21-9-7-18(17-30)8-10-21/h7-10,15-16,20H,3-6,11-14H2,1-2H3,(H,31,32,33)
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n/an/a 100n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137150
PNG
(US8871790, 218)
Show SMILES CCOc1nnc([nH]1)-c1cc(C(=O)N2CCC(F)(CC2)c2ccc(cc2)C#N)c(CC)cc1C1CCC1
Show InChI InChI=1S/C29H32FN5O2/c1-3-20-16-23(21-6-5-7-21)25(26-32-28(34-33-26)37-4-2)17-24(20)27(36)35-14-12-29(30,13-15-35)22-10-8-19(18-31)9-11-22/h8-11,16-17,21H,3-7,12-15H2,1-2H3,(H,32,33,34)
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n/an/a 170n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137156
PNG
(US8871790, 224)
Show SMILES COc1nnc([nH]1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C(F)(F)F)c(C)cc1C1CCC1
Show InChI InChI=1S/C27H29F3N4O2/c1-16-14-22(19-4-3-5-19)23(24-31-26(36-2)33-32-24)15-21(16)25(35)34-12-10-18(11-13-34)17-6-8-20(9-7-17)27(28,29)30/h6-9,14-15,18-19H,3-5,10-13H2,1-2H3,(H,31,32,33)
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n/an/a 160n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137164
PNG
(US8871790, 232)
Show SMILES CN(C)C(=O)c1cnc([nH]1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1C
Show InChI InChI=1S/C27H29N5O2/c1-17-13-18(2)23(14-22(17)25-29-16-24(30-25)27(34)31(3)4)26(33)32-11-9-21(10-12-32)20-7-5-19(15-28)6-8-20/h5-8,13-14,16,21H,9-12H2,1-4H3,(H,29,30)
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n/an/a 650n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137185
PNG
(US8871790, 253)
Show SMILES Cc1cc(C2CCC2)c(cc1C(=O)N1CCC(CC1)c1ccc(cc1)C#N)-c1ncc([nH]1)C#N
Show InChI InChI=1S/C28H27N5O/c1-18-13-25(22-3-2-4-22)26(27-31-17-23(16-30)32-27)14-24(18)28(34)33-11-9-21(10-12-33)20-7-5-19(15-29)6-8-20/h5-8,13-14,17,21-22H,2-4,9-12H2,1H3,(H,31,32)
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n/an/a 90n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137191
PNG
(US8871790, 259)
Show SMILES CCc1nnc([nH]1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1SC
Show InChI InChI=1S/C25H27N5OS/c1-4-23-27-24(29-28-23)21-14-20(16(2)13-22(21)32-3)25(31)30-11-9-19(10-12-30)18-7-5-17(15-26)6-8-18/h5-8,13-14,19H,4,9-12H2,1-3H3,(H,27,28,29)
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n/an/a 1.33E+3n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137199
PNG
(US8871790, 267)
Show SMILES Cc1ccc(cc1C(=O)Nc1ccc(nc1)N1CCCC1)C(=O)N1CCC(CC1)c1ccncc1
Show InChI InChI=1S/C28H31N5O2/c1-20-4-5-23(28(35)33-16-10-22(11-17-33)21-8-12-29-13-9-21)18-25(20)27(34)31-24-6-7-26(30-19-24)32-14-2-3-15-32/h4-9,12-13,18-19,22H,2-3,10-11,14-17H2,1H3,(H,31,34)
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n/an/a 3.03E+4n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM50426438
PNG
(CHEMBL2322367)
Show SMILES CN1CCN(CC1)c1cc2nc([nH]c2cn1)-c1cc(ccc1C)C(=O)N1CCC(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C31H33N7O/c1-21-3-6-25(31(39)38-11-9-24(10-12-38)23-7-4-22(19-32)5-8-23)17-26(21)30-34-27-18-29(33-20-28(27)35-30)37-15-13-36(2)14-16-37/h3-8,17-18,20,24H,9-16H2,1-2H3,(H,34,35)
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n/an/a 520n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137212
PNG
(US8871790, 282)
Show SMILES CC(C)c1nnc(Nc2cc(ccc2C)C(=O)N2CCC(CC2)c2ccc(cc2)C#N)[nH]1
Show InChI InChI=1S/C25H28N6O/c1-16(2)23-28-25(30-29-23)27-22-14-21(7-4-17(22)3)24(32)31-12-10-20(11-13-31)19-8-5-18(15-26)6-9-19/h4-9,14,16,20H,10-13H2,1-3H3,(H2,27,28,29,30)
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n/an/a 3.01E+4n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137219
PNG
(US8871790, 290)
Show SMILES CC(C)NC(=O)c1cncc(Nc2cc(ccc2C)C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c1
Show InChI InChI=1S/C29H31N5O2/c1-19(2)32-28(35)25-14-26(18-31-17-25)33-27-15-24(7-4-20(27)3)29(36)34-12-10-23(11-13-34)22-8-5-21(16-30)6-9-22/h4-9,14-15,17-19,23,33H,10-13H2,1-3H3,(H,32,35)
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n/an/a 470n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137223
PNG
(US8871790, 295)
Show SMILES CN1CCN(CC1)C(=O)c1ccnc(Nc2cc(ccc2C)C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c1
Show InChI InChI=1S/C31H34N6O2/c1-22-3-6-26(30(38)36-13-10-25(11-14-36)24-7-4-23(21-32)5-8-24)19-28(22)34-29-20-27(9-12-33-29)31(39)37-17-15-35(2)16-18-37/h3-9,12,19-20,25H,10-11,13-18H2,1-2H3,(H,33,34)
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n/an/a 3.82E+3n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137226
PNG
(US8871790, 302)
Show SMILES COCCNC(=O)Nc1cc(cnn1)C(=O)N1CCC(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C21H24N6O3/c1-30-11-8-23-21(29)25-19-12-18(14-24-26-19)20(28)27-9-6-17(7-10-27)16-4-2-15(13-22)3-5-16/h2-5,12,14,17H,6-11H2,1H3,(H2,23,25,26,29)
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n/an/a>5.00E+4n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137246
PNG
(US8871790, 325)
Show SMILES CN1CCC(CNC(=O)Nc2cc(ccc2C)C(=O)N2CCC(F)(CC2)c2ccc(cc2)C#N)CC1
Show InChI InChI=1S/C28H34FN5O2/c1-20-3-6-23(17-25(20)32-27(36)31-19-22-9-13-33(2)14-10-22)26(35)34-15-11-28(29,12-16-34)24-7-4-21(18-30)5-8-24/h3-8,17,22H,9-16,19H2,1-2H3,(H2,31,32,36)
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n/an/a 340n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137257
PNG
(US8871790, 337)
Show SMILES CC(=O)N1CCC(C1)OC(=O)Nc1ccc(C)c(c1)C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C27H29FN4O4/c1-18-3-8-22(30-26(35)36-23-9-12-32(17-23)19(2)33)15-24(18)25(34)31-13-10-27(28,11-14-31)21-6-4-20(16-29)5-7-21/h3-8,15,23H,9-14,17H2,1-2H3,(H,30,35)
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n/an/a 165n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137268
PNG
(US8871790, 348)
Show SMILES Cc1ncc(cc1NC(=O)c1ccc(nc1)N1CCCC1)C(=O)N1CCC(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C29H30N6O2/c1-20-26(33-28(36)24-8-9-27(32-18-24)34-12-2-3-13-34)16-25(19-31-20)29(37)35-14-10-23(11-15-35)22-6-4-21(17-30)5-7-22/h4-9,16,18-19,23H,2-3,10-15H2,1H3,(H,33,36)
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n/an/a 455n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137273
PNG
(US8871790, 353)
Show SMILES Cc1ccc(cc1NC(=O)N1CCCC1)C(=O)N1CCC2(CC1)OCc1cc(ccc21)C#N
Show InChI InChI=1S/C26H28N4O3/c1-18-4-6-20(15-23(18)28-25(32)30-10-2-3-11-30)24(31)29-12-8-26(9-13-29)22-7-5-19(16-27)14-21(22)17-33-26/h4-7,14-15H,2-3,8-13,17H2,1H3,(H,28,32)
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n/an/a 1.85E+4n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137275
PNG
(US8871790, 355)
Show SMILES CC(C)Nc1ccc(cn1)C(=O)Nc1cc(ccc1C)C(=O)N1CCC2(CC1)OCc1cc(ccc21)C#N
Show InChI InChI=1S/C30H31N5O3/c1-19(2)33-27-9-7-23(17-32-27)28(36)34-26-15-22(6-4-20(26)3)29(37)35-12-10-30(11-13-35)25-8-5-21(16-31)14-24(25)18-38-30/h4-9,14-15,17,19H,10-13,18H2,1-3H3,(H,32,33)(H,34,36)
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n/an/a 140n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137278
PNG
(US8871790, 358)
Show SMILES Cc1ccc(cc1NC(=O)c1ccc(nc1)N1CCNCC1)C(=O)N1CCC2(CC1)OCc1cc(ccc21)C#N
Show InChI InChI=1S/C31H32N6O3/c1-21-2-4-23(17-27(21)35-29(38)24-5-7-28(34-19-24)36-14-10-33-11-15-36)30(39)37-12-8-31(9-13-37)26-6-3-22(18-32)16-25(26)20-40-31/h2-7,16-17,19,33H,8-15,20H2,1H3,(H,35,38)
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n/an/a 805n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137280
PNG
(US8871790, 360)
Show SMILES COCCNc1ccc(cn1)C(=O)Nc1cc(ccc1C)C(=O)N1CCC2(CC1)OCc1cc(ccc21)C#N
Show InChI InChI=1S/C30H31N5O4/c1-20-3-5-22(16-26(20)34-28(36)23-6-8-27(33-18-23)32-11-14-38-2)29(37)35-12-9-30(10-13-35)25-7-4-21(17-31)15-24(25)19-39-30/h3-8,15-16,18H,9-14,19H2,1-2H3,(H,32,33)(H,34,36)
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n/an/a 280n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137287
PNG
(US8871790, 368)
Show SMILES Cc1ccc(cc1NC(=O)NCC1CCCO1)C(=O)N1CCC2(CC1)OCc1cc(ccc21)C#N
Show InChI InChI=1S/C27H30N4O4/c1-18-4-6-20(14-24(18)30-26(33)29-16-22-3-2-12-34-22)25(32)31-10-8-27(9-11-31)23-7-5-19(15-28)13-21(23)17-35-27/h4-7,13-14,22H,2-3,8-12,16-17H2,1H3,(H2,29,30,33)
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n/an/a 310n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137289
PNG
(US8871790, 373)
Show SMILES Cc1ccc(cc1NC(=O)N1CCCC1)-c1nnc2CC(CCn12)c1ccc(cc1)C#N
Show InChI InChI=1S/C25H26N6O/c1-17-4-7-21(14-22(17)27-25(32)30-11-2-3-12-30)24-29-28-23-15-20(10-13-31(23)24)19-8-5-18(16-26)6-9-19/h4-9,14,20H,2-3,10-13,15H2,1H3,(H,27,32)
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n/an/a>5.00E+4n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137291
PNG
(US8871790, 375)
Show SMILES CC(C)CNC(=O)Nc1cc(ccc1C)-c1nnc2CC(CCn12)c1ccc(cc1)C#N
Show InChI InChI=1S/C25H28N6O/c1-16(2)15-27-25(32)28-22-12-21(7-4-17(22)3)24-30-29-23-13-20(10-11-31(23)24)19-8-5-18(14-26)6-9-19/h4-9,12,16,20H,10-11,13,15H2,1-3H3,(H2,27,28,32)
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n/an/a 6.36E+3n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137298
PNG
(US8871790, 383)
Show SMILES Cc1ccc(nc1NC(=O)NC1CCOC1)C(=O)N1CCC(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C24H27N5O3/c1-16-2-7-21(27-22(16)28-24(31)26-20-10-13-32-15-20)23(30)29-11-8-19(9-12-29)18-5-3-17(14-25)4-6-18/h2-7,19-20H,8-13,15H2,1H3,(H2,26,27,28,31)
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n/an/a>5.00E+4n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
Fatty acid synthase


(Homo sapiens (Human))		BDBM137305
PNG
(US8871790, 391)
Show SMILES CC(C)CNc1ccc(cn1)C(=O)Nc1cc(nn1C)C(=O)N1CCC(CC1)c1ccc(cc1)C#N
Show InChI InChI=1S/C27H31N7O2/c1-18(2)16-29-24-9-8-22(17-30-24)26(35)31-25-14-23(32-33(25)3)27(36)34-12-10-21(11-13-34)20-6-4-19(15-28)5-7-20/h4-9,14,17-18,21H,10-13,16H2,1-3H3,(H,29,30)(H,31,35)
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n/an/a>5.00E+4n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...

US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%