Affinity Data by PubMed id=10636243

PubMed code 10636243

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50084050 (3-(6-Chloro-pyridin-2-yl)-8-methyl-8-aza-bicyclo[3...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmacy and Biochemistry Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-quinuclidinyl benzilate to Muscarinic acetylcholine receptor M1 in rat brain cortex at 10e-5 M of compound concentratio...				Bioorg Med Chem Lett 10: 55-8 (2000) BindingDB Entry DOI: 10.7270/Q2VQ31X8
Institute of Pharmacy and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50084051 (3-(6-Chloro-pyridin-3-yl)-8-methyl-8-aza-bicyclo[3...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmacy and Biochemistry Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-quinuclidinyl benzilate to Muscarinic acetylcholine receptor M1 in rat brain cortex at 10e-5 M of compound concentratio...				Bioorg Med Chem Lett 10: 55-8 (2000) BindingDB Entry DOI: 10.7270/Q2VQ31X8
Institute of Pharmacy and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Rattus norvegicus (Rat))	BDBM50084053 (6-Chloro-1',2',3',6'-tetrahydro-[3,4']bipyridinyl;...) Show SMILES Clc1ccc(cn1)C1=CCNCC1 \|t:8\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmacy and Biochemistry Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to 5-hydroxytryptamine 1B receptor in rat striatum; Residual radioligand binding higher than 50%				Bioorg Med Chem Lett 10: 55-8 (2000) BindingDB Entry DOI: 10.7270/Q2VQ31X8
Institute of Pharmacy and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50084054 (6'-Chloro-1-methyl-1,2,5,6-tetrahydro-[3,3']bipyri...) Show SMILES CN1CCC=C(C1)c1ccc(Cl)nc1 \|c:4\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmacy and Biochemistry Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat heart atria at 10e-5 M of compound concentration				Bioorg Med Chem Lett 10: 55-8 (2000) BindingDB Entry DOI: 10.7270/Q2VQ31X8
Institute of Pharmacy and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50084051 (3-(6-Chloro-pyridin-3-yl)-8-methyl-8-aza-bicyclo[3...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmacy and Biochemistry Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat heart atria at 10e-5 M of compound concentration				Bioorg Med Chem Lett 10: 55-8 (2000) BindingDB Entry DOI: 10.7270/Q2VQ31X8
Institute of Pharmacy and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50084053 (6-Chloro-1',2',3',6'-tetrahydro-[3,4']bipyridinyl;...) Show SMILES Clc1ccc(cn1)C1=CCNCC1 \|t:8\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmacy and Biochemistry Curated by ChEMBL					Assay Description Inhibition of [3H]-8-hydroxy-2-dipropylamino-1,2,3,4-tetrahydronaphthalene binding to 5-hydroxytryptamine 1A receptor in hippocampus region of rat br...				Bioorg Med Chem Lett 10: 55-8 (2000) BindingDB Entry DOI: 10.7270/Q2VQ31X8
Institute of Pharmacy and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%