Found 24 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108509
(5-((E)-4,8-Dimethyl-nona-3,7-dienyl)-3a,4,7,7a-tet...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:11| Show InChI InChI=1S/C19H26O3/c1-13(2)6-4-7-14(3)8-5-9-15-10-11-16-17(12-15)19(21)22-18(16)20/h6,8,10,16-17H,4-5,7,9,11-12H2,1-3H3/b14-8+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description Binding affinity for human cloned Histamine H1 receptor expressed in CHO cells using [3H]pyrilamine as radioligand |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108512
(5-(4,8,12-Trimethyl-tridecyl)-3a,4,7,7a-tetrahydro...)Show SMILES CC(C)CCCC(C)CCCC(C)CCCC1=CCC2C(C1)C(=O)OC2=O |t:16| Show InChI InChI=1S/C24H40O3/c1-17(2)8-5-9-18(3)10-6-11-19(4)12-7-13-20-14-15-21-22(16-20)24(26)27-23(21)25/h14,17-19,21-22H,5-13,15-16H2,1-4H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 2.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108511
(5-(4-Methyl-pent-3-enyl)-3a,4,7,7a-tetrahydro-isob...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:6| Show InChI InChI=1S/C14H18O3/c1-9(2)4-3-5-10-6-7-11-12(8-10)14(16)17-13(11)15/h4,6,11-12H,3,5,7-8H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50059863
((Z)-2-Methyl-3-tetradecyl-but-2-enedioic acid | CH...)Show InChI InChI=1S/C19H34O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-17(19(22)23)16(2)18(20)21/h3-15H2,1-2H3,(H,20,21)(H,22,23)/b17-16- | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 9.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108509
(5-((E)-4,8-Dimethyl-nona-3,7-dienyl)-3a,4,7,7a-tet...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:11| Show InChI InChI=1S/C19H26O3/c1-13(2)6-4-7-14(3)8-5-9-15-10-11-16-17(12-15)19(21)22-18(16)20/h6,8,10,16-17H,4-5,7,9,11-12H2,1-3H3/b14-8+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.36E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108509
(5-((E)-4,8-Dimethyl-nona-3,7-dienyl)-3a,4,7,7a-tet...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:11| Show InChI InChI=1S/C19H26O3/c1-13(2)6-4-7-14(3)8-5-9-15-10-11-16-17(12-15)19(21)22-18(16)20/h6,8,10,16-17H,4-5,7,9,11-12H2,1-3H3/b14-8+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108507
(CHEMBL420797 | dodecanoic anhydride)Show InChI InChI=1S/C24H46O3/c1-3-5-7-9-11-13-15-17-19-21-23(25)27-24(26)22-20-18-16-14-12-10-8-6-4-2/h3-22H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 2.29E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108510
(((E)-3-Dodec-2-enyl)-dihydro-furan-2,5-dione | CHE...)Show InChI InChI=1S/C16H26O3/c1-2-3-4-5-6-7-8-9-10-11-12-14-13-15(17)19-16(14)18/h10-11,14H,2-9,12-13H2,1H3/b11-10+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 4.01E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108514
(2-Dodec-2-enyl-succinic acid | CHEMBL441996)Show InChI InChI=1S/C16H28O4/c1-2-3-4-5-6-7-8-9-10-11-12-14(16(19)20)13-15(17)18/h10-11,14H,2-9,12-13H2,1H3,(H,17,18)(H,19,20)/b11-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.02E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108505
(4-[(E)-3,7-Dimethyl-octa-2,6-dien-(E)-ylidene]-cyc...)Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]=[#6]-1/[#6]-[#6]-[#6](-[#6](-[#6]-1)-[#6](-[#8])=O)-[#6](-[#8])=O Show InChI InChI=1S/C18H26O4/c1-12(2)5-4-6-13(3)7-8-14-9-10-15(17(19)20)16(11-14)18(21)22/h5,7-8,15-16H,4,6,9-11H2,1-3H3,(H,19,20)(H,21,22)/b13-7+,14-8+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 4.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108511
(5-(4-Methyl-pent-3-enyl)-3a,4,7,7a-tetrahydro-isob...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:6| Show InChI InChI=1S/C14H18O3/c1-9(2)4-3-5-10-6-7-11-12(8-10)14(16)17-13(11)15/h4,6,11-12H,3,5,7-8H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.49E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108509
(5-((E)-4,8-Dimethyl-nona-3,7-dienyl)-3a,4,7,7a-tet...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6]-2-[#6](-[#6]-1)-[#6](=O)-[#8]-[#6]-2=O |t:11| Show InChI InChI=1S/C19H26O3/c1-13(2)6-4-7-14(3)8-5-9-15-10-11-16-17(12-15)19(21)22-18(16)20/h6,8,10,16-17H,4-5,7,9,11-12H2,1-3H3/b14-8+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 5.03E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of Farnesyltransferase |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108507
(CHEMBL420797 | dodecanoic anhydride)Show InChI InChI=1S/C24H46O3/c1-3-5-7-9-11-13-15-17-19-21-23(25)27-24(26)22-20-18-16-14-12-10-8-6-4-2/h3-22H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 8.54E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of farnesyl-protein transferase |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108515
(4-(4-Methyl-pent-3-enyl)-cyclohex-4-ene-1,2-dicarb...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6](-[#6](-[#6]-1)-[#6](-[#8])=O)-[#6](-[#8])=O |t:6| Show InChI InChI=1S/C14H20O4/c1-9(2)4-3-5-10-6-7-11(13(15)16)12(8-10)14(17)18/h4,6,11-12H,3,5,7-8H2,1-2H3,(H,15,16)(H,17,18) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 9.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108506
(4-(4,8,12-Trimethyl-tridecyl)-cyclohex-4-ene-1,2-d...)Show SMILES CC(C)CCCC(C)CCCC(C)CCCC1=CCC(C(C1)C(O)=O)C(O)=O |t:16| Show InChI InChI=1S/C24H42O4/c1-17(2)8-5-9-18(3)10-6-11-19(4)12-7-13-20-14-15-21(23(25)26)22(16-20)24(27)28/h14,17-19,21-22H,5-13,15-16H2,1-4H3,(H,25,26)(H,27,28) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108516
(4-(4,8,12-Trimethyl-tridecyl)-cyclohex-4-ene-1,2-d...)Show SMILES COC(=O)C1CC=C(CCCC(C)CCCC(C)CCCC(C)C)CC1C(=O)OC |t:6| Show InChI InChI=1S/C26H46O4/c1-19(2)10-7-11-20(3)12-8-13-21(4)14-9-15-22-16-17-23(25(27)29-5)24(18-22)26(28)30-6/h16,19-21,23-24H,7-15,17-18H2,1-6H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108506
(4-(4,8,12-Trimethyl-tridecyl)-cyclohex-4-ene-1,2-d...)Show SMILES CC(C)CCCC(C)CCCC(C)CCCC1=CCC(C(C1)C(O)=O)C(O)=O |t:16| Show InChI InChI=1S/C24H42O4/c1-17(2)8-5-9-18(3)10-6-11-19(4)12-7-13-20-14-15-21(23(25)26)22(16-20)24(27)28/h14,17-19,21-22H,5-13,15-16H2,1-4H3,(H,25,26)(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description Binding affinity for human cloned Histamine H1 receptor expressed in CHO cells using [3H]pyrilamine as radioligand |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108515
(4-(4-Methyl-pent-3-enyl)-cyclohex-4-ene-1,2-dicarb...)Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-1=[#6]-[#6]-[#6](-[#6](-[#6]-1)-[#6](-[#8])=O)-[#6](-[#8])=O |t:6| Show InChI InChI=1S/C14H20O4/c1-9(2)4-3-5-10-6-7-11(13(15)16)12(8-10)14(17)18/h4,6,11-12H,3,5,7-8H2,1-2H3,(H,15,16)(H,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of farnesyl-protein transferase |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108508
(3-Methylene-dihydro-furan-2,5-dione | CHEMBL87967)Show InChI InChI=1S/C5H4O3/c1-3-2-4(6)8-5(3)7/h1-2H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of farnesyl-protein transferase |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108505
(4-[(E)-3,7-Dimethyl-octa-2,6-dien-(E)-ylidene]-cyc...)Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]=[#6]-1/[#6]-[#6]-[#6](-[#6](-[#6]-1)-[#6](-[#8])=O)-[#6](-[#8])=O Show InChI InChI=1S/C18H26O4/c1-12(2)5-4-6-13(3)7-8-14-9-10-15(17(19)20)16(11-14)18(21)22/h5,7-8,15-16H,4,6,9-11H2,1-3H3,(H,19,20)(H,21,22)/b13-7+,14-8+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of farnesyl-protein transferase |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108514
(2-Dodec-2-enyl-succinic acid | CHEMBL441996)Show InChI InChI=1S/C16H28O4/c1-2-3-4-5-6-7-8-9-10-11-12-14(16(19)20)13-15(17)18/h10-11,14H,2-9,12-13H2,1H3,(H,17,18)(H,19,20)/b11-10+ | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of geranylgeranyl-protein transferase type-I |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108512
(5-(4,8,12-Trimethyl-tridecyl)-3a,4,7,7a-tetrahydro...)Show SMILES CC(C)CCCC(C)CCCC(C)CCCC1=CCC2C(C1)C(=O)OC2=O |t:16| Show InChI InChI=1S/C24H40O3/c1-17(2)8-5-9-18(3)10-6-11-19(4)12-7-13-20-14-15-21-22(16-20)24(26)27-23(21)25/h14,17-19,21-22H,5-13,15-16H2,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of farnesyl-protein transferase |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108508
(3-Methylene-dihydro-furan-2,5-dione | CHEMBL87967)Show InChI InChI=1S/C5H4O3/c1-3-2-4(6)8-5(3)7/h1-2H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description Binding affinity for human cloned 5-hydroxytryptamine 3 receptor |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha
(Homo sapiens (Human)) | BDBM50108510
(((E)-3-Dodec-2-enyl)-dihydro-furan-2,5-dione | CHE...)Show InChI InChI=1S/C16H26O3/c1-2-3-4-5-6-7-8-9-10-11-12-14-13-15(17)19-16(14)18/h10-11,14H,2-9,12-13H2,1H3/b11-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University College London
Curated by ChEMBL
| Assay Description In vitro inhibition of farnesyl-protein transferase |
Bioorg Med Chem Lett 12: 255-9 (2001)
BindingDB Entry DOI: 10.7270/Q2GQ6Z93 |
More data for this Ligand-Target Pair | |