Affinity Data by PubMed id=12036354

PubMed code 12036354

Found 23 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113815 (4-(2-Naphthalen-1-yl-ethyl)-5-piperidin-4-yl-isoxa...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1CCc1cccc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50000687 (2-(3-Carboxy-propyl)-6-(4-methoxy-phenyl)-2H-pyrid...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113817 (4-(2-Naphthalen-2-yl-ethyl)-5-piperidin-4-yl-isoxa...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1CCc1ccc2ccccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113806 (4-(3,3-Diphenyl-propyl)-5-piperidin-4-yl-isoxazol-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50095533 (4-(naphthalen-2-ylmethyl)-5-(piperidin-4-yl)isoxaz...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1Cc1ccc2ccccc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113810 (4-Naphthalen-1-ylmethyl-5-piperidin-4-yl-isoxazol-...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1Cc1cccc2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113812 (4-Benzhydryl-5-piperidin-4-yl-isoxazol-3-ol; hydro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113824 (4-Phenethyl-5-piperidin-4-yl-isoxazol-3-ol; hydrob...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1CCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113804 (4-Anthracen-9-ylmethyl-5-piperidin-4-yl-isoxazol-3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113813 (4-Biphenyl-4-ylmethyl-5-piperidin-4-yl-isoxazol-3-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113803 (4-Methyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobrom...) Show SMILES Cc1c(o[nH]c1=O)C1CCNCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113811 (4-(2,2-Diphenyl-ethyl)-5-piperidin-4-yl-isoxazol-3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113816 (4-Octyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobromi...) Show SMILES CCCCCCCCc1c(o[nH]c1=O)C1CCNCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113823 (4-Butyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobromi...) Show SMILES CCCCc1c(o[nH]c1=O)C1CCNCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113814 (4-Cyclohexylmethyl-5-piperidin-4-yl-isoxazol-3-ol;...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1CC1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113808 (4-Benzyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobrom...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113821 (4-Hexyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobromi...) Show SMILES CCCCCCc1c(o[nH]c1=O)C1CCNCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113805 (4-(3-Phenyl-propyl)-5-piperidin-4-yl-isoxazol-3-ol...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1CCCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113822 (5-(4-Methyl-piperidin-4-yl)-isoxazol-3-ol; hydrobr...) Show SMILES CC1(CCNCC1)c1cc(=O)[nH]o1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113819 (4-(4,4-Diphenyl-butyl)-5-piperidin-4-yl-isoxazol-3...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113818 (5-Piperidin-4-yl-4-propyl-isoxazol-3-ol; hydrobrom...) Show SMILES CCCc1c(o[nH]c1=O)C1CCNCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50113809 (4-Ethyl-5-piperidin-4-yl-isoxazol-3-ol; hydrobromi...) Show SMILES CCc1c(o[nH]c1=O)C1CCNCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Rattus norvegicus (Rat))	BDBM50032954 (5-(piperidin-4-yl)isoxazol-3-ol \| 5-Piperidin-4-yl...) Show SMILES O=c1cc(o[nH]1)C1CCNCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Affinity for GABA-B receptor by inhibiting GABA uptake into rat brain synaptosomes				J Med Chem 45: 2454-68 (2002) BindingDB Entry DOI: 10.7270/Q2D21Z91
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%