Found 43 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50052442
((4-Hydroxy-3-methoxy-phenyl)-acetic acid (2R,3S,3a...)Show SMILES COc1cc(CC(=O)OCC2=C[C@H]3[C@H]4O[C@]5(Cc6ccccc6)O[C@]4(C[C@@H](C)[C@]3(O5)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)C(C)=C)ccc1O |r,t:10,35,THB:23:15:26.25.24:12| Show InChI InChI=1S/C37H40O9/c1-21(2)35-17-23(4)37-27(33(35)44-36(45-35,46-37)19-24-9-7-6-8-10-24)14-26(18-34(41)30(37)13-22(3)32(34)40)20-43-31(39)16-25-11-12-28(38)29(15-25)42-5/h6-15,23,27,30,33,38,41H,1,16-20H2,2-5H3/t23-,27+,30-,33-,34-,35-,36-,37-/m1/s1 | PDB
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Article
PubMed
| 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding to Rat Vanilloid receptor 1 (VR1) expressing CHO cells compared to capsacin |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50196343
(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(cc2)C(C)(C)C)ccc1O Show InChI InChI=1S/C28H40N2O4S/c1-27(2,3)22-11-8-19(9-12-22)14-21(18-34-25(32)28(4,5)6)17-30-26(35)29-16-20-10-13-23(31)24(15-20)33-7/h8-13,15,21,31H,14,16-18H2,1-7H3,(H2,29,30,35) | PDB
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| 6.35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20293
(2-[(3,4-dimethylphenyl)methyl]-3-({[(3-fluoro-4-me...)Show SMILES Cc1ccc(CC(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)COC(=O)C(C)(C)C)cc1C Show InChI InChI=1S/C26H36FN3O4S2/c1-17-7-8-19(11-18(17)2)12-21(16-34-24(31)26(3,4)5)15-29-25(35)28-14-20-9-10-23(22(27)13-20)30-36(6,32)33/h7-11,13,21,30H,12,14-16H2,1-6H3,(H2,28,29,35) | PDB
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| 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibition of capsaicin-induced [Ca2+] uptake by Rat Vanilloid receptor 1 (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50196337
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)ccc1O Show InChI InChI=1S/C26H36N2O4S/c1-17-7-8-19(11-18(17)2)12-21(16-32-24(30)26(3,4)5)15-28-25(33)27-14-20-9-10-22(29)23(13-20)31-6/h7-11,13,21,29H,12,14-16H2,1-6H3,(H2,27,28,33) | PDB
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| 17.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130546
(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O Show InChI InChI=1S/C29H43N3O5S2/c1-28(2,3)23-12-9-20(10-13-23)15-22(19-37-26(33)29(4,5)6)18-31-27(38)30-17-21-11-14-24(25(16-21)36-7)32-39(8,34)35/h9-14,16,22,32H,15,17-19H2,1-8H3,(H2,30,31,38) | PDB
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| 25.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130542
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES Cc1ccc(CC(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)COC(=O)C(C)(C)C)cc1C Show InChI InChI=1S/C26H37N3O4S2/c1-18-7-8-21(13-19(18)2)14-22(17-33-24(30)26(3,4)5)16-28-25(34)27-15-20-9-11-23(12-10-20)29-35(6,31)32/h7-13,22,29H,14-17H2,1-6H3,(H2,27,28,34) | PDB
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| 29.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130548
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)ccc1NS(C)(=O)=O Show InChI InChI=1S/C27H39N3O5S2/c1-18-8-9-20(12-19(18)2)13-22(17-35-25(31)27(3,4)5)16-29-26(36)28-15-21-10-11-23(24(14-21)34-6)30-37(7,32)33/h8-12,14,22,30H,13,15-17H2,1-7H3,(H2,28,29,36) | PDB
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| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20293
(2-[(3,4-dimethylphenyl)methyl]-3-({[(3-fluoro-4-me...)Show SMILES Cc1ccc(CC(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)COC(=O)C(C)(C)C)cc1C Show InChI InChI=1S/C26H36FN3O4S2/c1-17-7-8-19(11-18(17)2)12-21(16-34-24(31)26(3,4)5)15-29-25(35)28-14-20-9-10-23(22(27)13-20)30-36(6,32)33/h7-11,13,21,30H,12,14-16H2,1-6H3,(H2,28,29,35) | PDB
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PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130540
(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)Show SMILES CC(C)(C)C(=O)OCC(CNC(=S)NCc1ccc(NS(C)(=O)=O)cc1)Cc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C28H41N3O4S2/c1-27(2,3)23-12-8-20(9-13-23)16-22(19-35-25(32)28(4,5)6)18-30-26(36)29-17-21-10-14-24(15-11-21)31-37(7,33)34/h8-15,22,31H,16-19H2,1-7H3,(H2,29,30,36) | PDB
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| 64 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130542
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES Cc1ccc(CC(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)COC(=O)C(C)(C)C)cc1C Show InChI InChI=1S/C26H37N3O4S2/c1-18-7-8-21(13-19(18)2)14-22(17-33-24(30)26(3,4)5)16-28-25(34)27-15-20-9-11-23(12-10-20)29-35(6,31)32/h7-13,22,29H,14-17H2,1-6H3,(H2,27,28,34) | PDB
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| 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibition of capsaicin-induced [Ca2+] uptake by Rat Vanilloid receptor 1 (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130544
(Benzoic acid 2-(4-tert-butyl-benzyl)-3-[3-(4-metha...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)c2ccccc2)Cc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O Show InChI InChI=1S/C31H39N3O5S2/c1-31(2,3)26-14-11-22(12-15-26)17-24(21-39-29(35)25-9-7-6-8-10-25)20-33-30(40)32-19-23-13-16-27(28(18-23)38-4)34-41(5,36)37/h6-16,18,24,34H,17,19-21H2,1-5H3,(H2,32,33,40) | PDB
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PC sid
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| 77.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130540
(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)Show SMILES CC(C)(C)C(=O)OCC(CNC(=S)NCc1ccc(NS(C)(=O)=O)cc1)Cc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C28H41N3O4S2/c1-27(2,3)23-12-8-20(9-13-23)16-22(19-35-25(32)28(4,5)6)18-30-26(36)29-17-21-10-14-24(15-11-21)31-37(7,33)34/h8-15,22,31H,16-19H2,1-7H3,(H2,29,30,36) | PDB
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PubMed
| 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibition of capsaicin-induced [Ca2+] uptake by Rat Vanilloid receptor 1 (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130553
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES CCS(=O)(=O)Nc1ccc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)cc1 Show InChI InChI=1S/C27H39N3O4S2/c1-7-36(32,33)30-24-12-10-21(11-13-24)16-28-26(35)29-17-23(18-34-25(31)27(4,5)6)15-22-9-8-19(2)20(3)14-22/h8-14,23,30H,7,15-18H2,1-6H3,(H2,28,29,35) | PDB
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| 108 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130552
(Benzoic acid 2-(3,4-dimethyl-benzyl)-3-[3-(4-metha...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)c2ccccc2)Cc2ccc(C)c(C)c2)ccc1NS(C)(=O)=O Show InChI InChI=1S/C29H35N3O5S2/c1-20-10-11-22(14-21(20)2)15-24(19-37-28(33)25-8-6-5-7-9-25)18-31-29(38)30-17-23-12-13-26(27(16-23)36-3)32-39(4,34)35/h5-14,16,24,32H,15,17-19H2,1-4H3,(H2,30,31,38) | PDB
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| 148 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130539
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES CC(C)S(=O)(=O)Nc1ccc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)cc1 Show InChI InChI=1S/C28H41N3O4S2/c1-19(2)37(33,34)31-25-12-10-22(11-13-25)16-29-27(36)30-17-24(18-35-26(32)28(5,6)7)15-23-9-8-20(3)21(4)14-23/h8-14,19,24,31H,15-18H2,1-7H3,(H2,29,30,36) | PDB
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| 227 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130545
(Benzoic acid 2-(4-tert-butyl-benzyl)-3-[3-(4-metha...)Show SMILES CC(C)(C)c1ccc(CC(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)COC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C30H37N3O4S2/c1-30(2,3)26-14-10-22(11-15-26)18-24(21-37-28(34)25-8-6-5-7-9-25)20-32-29(38)31-19-23-12-16-27(17-13-23)33-39(4,35)36/h5-17,24,33H,18-21H2,1-4H3,(H2,31,32,38) | PDB
MMDB
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KEGG
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UniChem
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PubMed
| 239 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130553
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES CCS(=O)(=O)Nc1ccc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)cc1 Show InChI InChI=1S/C27H39N3O4S2/c1-7-36(32,33)30-24-12-10-21(11-13-24)16-28-26(35)29-17-23(18-34-25(31)27(4,5)6)15-22-9-8-19(2)20(3)14-22/h8-14,23,30H,7,15-18H2,1-6H3,(H2,28,29,35) | PDB
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PubMed
| 309 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibition of capsaicin-induced [Ca2+] uptake by Rat Vanilloid receptor 1 (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130543
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES CCCS(=O)(=O)Nc1ccc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)cc1 Show InChI InChI=1S/C28H41N3O4S2/c1-7-14-37(33,34)31-25-12-10-22(11-13-25)17-29-27(36)30-18-24(19-35-26(32)28(4,5)6)16-23-9-8-20(2)21(3)15-23/h8-13,15,24,31H,7,14,16-19H2,1-6H3,(H2,29,30,36) | PDB
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| 313 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130555
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES Cc1ccc(CC(CNC(=S)NCc2cccc(NS(C)(=O)=O)c2)COC(=O)C(C)(C)C)cc1C Show InChI InChI=1S/C26H37N3O4S2/c1-18-10-11-20(12-19(18)2)13-22(17-33-24(30)26(3,4)5)16-28-25(34)27-15-21-8-7-9-23(14-21)29-35(6,31)32/h7-12,14,22,29H,13,15-17H2,1-6H3,(H2,27,28,34) | PDB
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| 355 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130556
(Benzoic acid 2-(3,4-dimethyl-benzyl)-3-[3-(4-metha...)Show SMILES Cc1ccc(CC(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)COC(=O)c2ccccc2)cc1C Show InChI InChI=1S/C28H33N3O4S2/c1-20-9-10-23(15-21(20)2)16-24(19-35-27(32)25-7-5-4-6-8-25)18-30-28(36)29-17-22-11-13-26(14-12-22)31-37(3,33)34/h4-15,24,31H,16-19H2,1-3H3,(H2,29,30,36) | PDB
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| 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20284
(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)Show InChI InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25) | PDB
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Article
PubMed
| 520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibition of capsaicin-induced [Ca2+] uptake by Rat Vanilloid receptor 1 (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130543
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES CCCS(=O)(=O)Nc1ccc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)cc1 Show InChI InChI=1S/C28H41N3O4S2/c1-7-14-37(33,34)31-25-12-10-22(11-13-25)17-29-27(36)30-18-24(19-35-26(32)28(4,5)6)16-23-9-8-20(2)21(3)15-23/h8-13,15,24,31H,7,14,16-19H2,1-6H3,(H2,29,30,36) | PDB
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| 940 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibition of capsaicin-induced [Ca2+] uptake by Rat Vanilloid receptor 1 (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20284
(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)Show InChI InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25) | PDB
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| 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20461
((6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methy...)Show InChI InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+ | PDB
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| 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding to Rat Vanilloid receptor 1 (VR1) expressing CHO cells compared to capsacin |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130538
(2,2-Dimethyl-propionic acid 3-[3-(4-acetylamino-be...)Show SMILES CC(=O)Nc1ccc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)cc1 Show InChI InChI=1S/C27H37N3O3S/c1-18-7-8-22(13-19(18)2)14-23(17-33-25(32)27(4,5)6)16-29-26(34)28-15-21-9-11-24(12-10-21)30-20(3)31/h7-13,23H,14-17H2,1-6H3,(H,30,31)(H2,28,29,34) | PDB
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| 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20461
((6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methy...)Show InChI InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+ | PDB
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| 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130550
(2,2-Dimethyl-propionic acid 3-[3-(4-benzenesulfony...)Show SMILES Cc1ccc(CC(CNC(=S)NCc2ccc(NS(=O)(=O)c3ccccc3)cc2)COC(=O)C(C)(C)C)cc1C Show InChI InChI=1S/C31H39N3O4S2/c1-22-11-12-25(17-23(22)2)18-26(21-38-29(35)31(3,4)5)20-33-30(39)32-19-24-13-15-27(16-14-24)34-40(36,37)28-9-7-6-8-10-28/h6-17,26,34H,18-21H2,1-5H3,(H2,32,33,39) | PDB
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| 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130554
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES CC(C)C(=O)Nc1ccc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)cc1 Show InChI InChI=1S/C29H41N3O3S/c1-19(2)26(33)32-25-12-10-22(11-13-25)16-30-28(36)31-17-24(18-35-27(34)29(5,6)7)15-23-9-8-20(3)21(4)14-23/h8-14,19,24H,15-18H2,1-7H3,(H,32,33)(H2,30,31,36) | PDB
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| 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130551
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES Cc1ccc(CC(CNC(=S)NCc2ccc(CNS(C)(=O)=O)cc2)COC(=O)C(C)(C)C)cc1C Show InChI InChI=1S/C27H39N3O4S2/c1-19-7-8-23(13-20(19)2)14-24(18-34-25(31)27(3,4)5)16-29-26(35)28-15-21-9-11-22(12-10-21)17-30-36(6,32)33/h7-13,24,30H,14-18H2,1-6H3,(H2,28,29,35) | PDB
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| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]-RTX displacement. |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20461
((6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methy...)Show InChI InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+ | PDB
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| n/a | n/a | n/a | n/a | 44.8 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50196343
(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(cc2)C(C)(C)C)ccc1O Show InChI InChI=1S/C28H40N2O4S/c1-27(2,3)22-11-8-19(9-12-22)14-21(18-34-25(32)28(4,5)6)17-30-26(35)29-16-20-10-13-23(31)24(15-20)33-7/h8-13,15,21,31H,14,16-18H2,1-7H3,(H2,29,30,35) | PDB
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| n/a | n/a | n/a | n/a | 2.83 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130551
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES Cc1ccc(CC(CNC(=S)NCc2ccc(CNS(C)(=O)=O)cc2)COC(=O)C(C)(C)C)cc1C Show InChI InChI=1S/C27H39N3O4S2/c1-19-7-8-23(13-20(19)2)14-24(18-34-25(31)27(3,4)5)16-29-26(35)28-15-21-9-11-22(12-10-21)17-30-36(6,32)33/h7-13,24,30H,14-18H2,1-6H3,(H2,28,29,35) | PDB
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| n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130556
(Benzoic acid 2-(3,4-dimethyl-benzyl)-3-[3-(4-metha...)Show SMILES Cc1ccc(CC(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)COC(=O)c2ccccc2)cc1C Show InChI InChI=1S/C28H33N3O4S2/c1-20-9-10-23(15-21(20)2)16-24(19-35-27(32)25-7-5-4-6-8-25)18-30-28(36)29-17-22-11-13-26(14-12-22)31-37(3,33)34/h4-15,24,31H,16-19H2,1-3H3,(H2,29,30,36) | PDB
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| n/a | n/a | n/a | n/a | 1.73E+3 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50196337
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)ccc1O Show InChI InChI=1S/C26H36N2O4S/c1-17-7-8-19(11-18(17)2)12-21(16-32-24(30)26(3,4)5)15-28-25(33)27-14-20-9-10-22(29)23(13-20)31-6/h7-11,13,21,29H,12,14-16H2,1-6H3,(H2,27,28,33) | PDB
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| n/a | n/a | n/a | n/a | 1.97 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130544
(Benzoic acid 2-(4-tert-butyl-benzyl)-3-[3-(4-metha...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)c2ccccc2)Cc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O Show InChI InChI=1S/C31H39N3O5S2/c1-31(2,3)26-14-11-22(12-15-26)17-24(21-39-29(35)25-9-7-6-8-10-25)20-33-30(40)32-19-23-13-16-27(28(18-23)38-4)34-41(5,36)37/h6-16,18,24,34H,17,19-21H2,1-5H3,(H2,32,33,40) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 252 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130555
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES Cc1ccc(CC(CNC(=S)NCc2cccc(NS(C)(=O)=O)c2)COC(=O)C(C)(C)C)cc1C Show InChI InChI=1S/C26H37N3O4S2/c1-18-10-11-20(12-19(18)2)13-22(17-33-24(30)26(3,4)5)16-28-25(34)27-15-21-8-7-9-23(14-21)29-35(6,31)32/h7-12,14,22,29H,13,15-17H2,1-6H3,(H2,27,28,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 990 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130546
(2,2-Dimethyl-propionic acid 2-(4-tert-butyl-benzyl...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O Show InChI InChI=1S/C29H43N3O5S2/c1-28(2,3)23-12-9-20(10-13-23)15-22(19-37-26(33)29(4,5)6)18-31-27(38)30-17-21-11-14-24(25(16-21)36-7)32-39(8,34)35/h9-14,16,22,32H,15,17-19H2,1-8H3,(H2,30,31,38) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130538
(2,2-Dimethyl-propionic acid 3-[3-(4-acetylamino-be...)Show SMILES CC(=O)Nc1ccc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)cc1 Show InChI InChI=1S/C27H37N3O3S/c1-18-7-8-22(13-19(18)2)14-23(17-33-25(32)27(4,5)6)16-29-26(34)28-15-21-9-11-24(12-10-21)30-20(3)31/h7-13,23H,14-17H2,1-6H3,(H,30,31)(H2,28,29,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 450 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130552
(Benzoic acid 2-(3,4-dimethyl-benzyl)-3-[3-(4-metha...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)c2ccccc2)Cc2ccc(C)c(C)c2)ccc1NS(C)(=O)=O Show InChI InChI=1S/C29H35N3O5S2/c1-20-10-11-22(14-21(20)2)15-24(19-37-28(33)25-8-6-5-7-9-25)18-31-29(38)30-17-23-12-13-26(27(16-23)36-3)32-39(4,34)35/h5-14,16,24,32H,15,17-19H2,1-4H3,(H2,30,31,38) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 166 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130548
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)ccc1NS(C)(=O)=O Show InChI InChI=1S/C27H39N3O5S2/c1-18-8-9-20(12-19(18)2)13-22(17-35-25(31)27(3,4)5)16-29-26(36)28-15-21-10-11-23(24(14-21)34-6)30-37(7,32)33/h8-12,14,22,30H,13,15-17H2,1-7H3,(H2,28,29,36) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130554
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES CC(C)C(=O)Nc1ccc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)cc1 Show InChI InChI=1S/C29H41N3O3S/c1-19(2)26(33)32-25-12-10-22(11-13-25)16-30-28(36)31-17-24(18-35-27(34)29(5,6)7)15-23-9-8-20(3)21(4)14-23/h8-14,19,24H,15-18H2,1-7H3,(H,32,33)(H2,30,31,36) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.14E+3 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130539
(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)Show SMILES CC(C)S(=O)(=O)Nc1ccc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)cc1 Show InChI InChI=1S/C28H41N3O4S2/c1-19(2)37(33,34)31-25-12-10-22(11-13-25)16-29-27(36)30-17-24(18-35-26(32)28(5,6)7)15-23-9-8-20(3)21(4)14-23/h8-14,19,24,31H,15-18H2,1-7H3,(H2,29,30,36) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 790 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50130545
(Benzoic acid 2-(4-tert-butyl-benzyl)-3-[3-(4-metha...)Show SMILES CC(C)(C)c1ccc(CC(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)COC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C30H37N3O4S2/c1-30(2,3)26-14-10-22(11-15-26)18-24(21-37-28(34)25-8-6-5-7-9-25)20-32-29(38)31-19-23-12-16-27(17-13-23)33-39(4,35)36/h5-17,24,33H,18-21H2,1-4H3,(H2,31,32,38) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.79E+3 | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells |
J Med Chem 46: 3116-26 (2003)
Article DOI: 10.1021/jm030089u
BindingDB Entry DOI: 10.7270/Q2SB4551 |
More data for this
Ligand-Target Pair | |
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