Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001169 (2-benzo[d][1,3]thiazol-2-ylsulfanyl-1-ethanamino-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 90 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001184 (2-(6-Isopropyl-benzothiazol-2-ylsulfanyl)-ethylami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001187 (3-(5-Chloro-benzothiazol-2-ylsulfanyl)-N-hydroxy-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001170 (5-ethyloxy-2-benzo[d][1,3]thiazol-2-ylsulfanyl-1-e...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001179 (3-(Benzothiazol-2-ylsulfanyl)-N-hydroxy-N-methyl-a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001182 (2-(5-Chloro-benzothiazol-2-ylsulfanyl)-ethylamine-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001178 (2-(7-Chloro-benzothiazol-2-ylsulfanyl)-ethylamine-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 530 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001177 (2-(6-Ethoxy-benzothiazol-2-ylsulfanyl)-ethylamine-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 390 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001185 (2-(5-Chloro-benzothiazol-2-ylsulfanyl)-ethylamine-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.45E+4 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001168 (3-(Benzothiazol-2-ylsulfanyl)-propylamine-N-hydrox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001174 (2-(Benzothiazol-2-ylsulfanyl)-ethylamine-N-hydroxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001180 (2-(Benzothiazol-2-ylsulfanyl)-N-hydroxy-N-methyl-a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001175 (C-(Benzothiazol-2-ylsulfanyl)-methylamine-N-hydrox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001186 (2-(5-Trifluoromethyl-benzothiazol-2-ylsulfanyl)-et...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50000540 (1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001172 (2-benzo[d][1,3]thiazol-2-ylsulfanyl-1-ethanamino-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | DrugBank PubMed | n/a | n/a | n/a | n/a | 470 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001176 (2-(5-Chloro-benzothiazol-2-ylsulfanyl)-ethylamine-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001181 (3-(Benzothiazol-2-ylsulfanyl)-N-hydroxy-N-methyl-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 39 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001183 (3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human)) | BDBM50001171 (3-(Benzothiazol-2-ylsulfanyl)-propylamine-N-hydrox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 45 | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of ionophore stimulated LTB4 release from human peripheral blood leukocytes. | J Med Chem 35: 3180-3 (1992) BindingDB Entry DOI: 10.7270/Q2542P68 | |||||||||||
More data for this Ligand-Target Pair |