Affinity Data by PubMed id=15686933

PubMed code 15686933

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50154496 ((R)-5-(4-Bromo-benzyl)-3-(3,5-dichloro-phenyl)-1,5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
Cerep Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160927 ((6S,7aS)-6-(4''-Bromo-biphenyl-3-ylmethoxy)-2-(3,5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
Cerep Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160919 ((6S,7aS)-6-[(4''-Bromo-biphenyl-3-ylmethyl)-methyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
Cerep Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160925 (3''-{[(6S,7aS)-2-(3,5-Dichloro-phenyl)-1,3-dioxo-h...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
Cerep Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160924 (3''-[(6S,7aS)-2-(3,5-Dichloro-phenyl)-1,3-dioxo-he...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
Cerep Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160920 ((6R,7aS)-6-(4''-Bromo-biphenyl-3-ylmethoxy)-2-(3,5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
Cerep Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160929 ((6S,7aS)-6-(4''-Bromo-biphenyl-3-ylmethylsulfanyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
Cerep Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160923 ((6S,7aS)-6-(4''-Bromo-biphenyl-4-yloxy)-2-(3,5-dic...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
Cerep Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160928 ((6R,7aR)-6-(4''-Chloro-biphenyl-3-ylmethoxy)-2-(3,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
Cerep Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160926 (3''-({[(6S,7aS)-2-(3,5-Dichloro-phenyl)-1,3-dioxo-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
Cerep Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160921 ((6S,7aS)-6-(3''-Bromo-biphenyl-3-ylmethoxy)-2-(3,5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	755	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
Cerep Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-L/beta-2 (Homo sapiens (Human))	BDBM50160920 ((6R,7aS)-6-(4''-Bromo-biphenyl-3-ylmethoxy)-2-(3,5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	935	n/a	n/a	n/a	n/a	n/a	n/a
Cerep Curated by ChEMBL					Assay Description Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assay				Bioorg Med Chem Lett 15: 1161-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.007 BindingDB Entry DOI: 10.7270/Q2NP23W2
Cerep Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%