Affinity Data by PubMed id=16610801

PubMed code 16610801

Found 34 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50185321 (6-cyano-7-nitroquinoxaline-2,3-dione \| 7-nitro-2,3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM26431 ((2R)-2-aminopentanedioic acid \| CHEMBL76232 \| D-Gl...) Show SMILES N[C@H](CCC(O)=O)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50185318 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxythiophe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50178141 ((S)-1-(2-amino-2-carboxyethyl)-3-(4-carboxybenzyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50185319 ((S)-1-(2-amino-2-carboxyethyl)-3-(4-sulfobenzyl)py...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50185320 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxyfuran-3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50185328 ((S)-1-(2-amino-2-carboxyethyl)-3-(tetrazol-5-ylmet...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50185322 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-tetrazol-5-yle...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human))	BDBM50185318 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxythiophe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from human GLUK7 expressed in HEK293 cell membranes				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50178138 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxyethyl)p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50185327 ((R)-1-(2-amino-2-carboxyethyl)-3-(2-carboxythiophe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50178136 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus)	BDBM50185323 ((RS)-1-(2-amino-2-carboxyethyl)-3-(4-phosphonobenz...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from rat GLUK6 expressed in HEK293 cells				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50185318 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxythiophe...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUK5 by FLIPR assay				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 4 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA4				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 3 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA3				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA2				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 1 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA1				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, kainate 2 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUK6				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUK5 by FLIPR assay				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human))	BDBM50185318 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxythiophe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.64E+5	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Displacement of [3H]kainate from human GLUK7 expressed in HEK293 cell membranes				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50178138 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxyethyl)p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	7.31E+4	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50185322 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-tetrazol-5-yle...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.37E+4	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50185318 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxythiophe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50185319 ((S)-1-(2-amino-2-carboxyethyl)-3-(4-sulfobenzyl)py...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.68E+3	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50185328 ((S)-1-(2-amino-2-carboxyethyl)-3-(tetrazol-5-ylmet...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.02E+4	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50185323 ((RS)-1-(2-amino-2-carboxyethyl)-3-(4-phosphonobenz...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50185320 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxyfuran-3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50185324 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-phosphonobenzy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50185321 (6-cyano-7-nitroquinoxaline-2,3-dione \| 7-nitro-2,3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50178136 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	402	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (Homo sapiens (Human))	BDBM26431 ((2R)-2-aminopentanedioic acid \| CHEMBL76232 \| D-Gl...) Show SMILES N[C@H](CCC(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Induction of calcium influx in HEK293 cells expressing human GLUK5 by FLIPR assay				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.78E+3	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 5 (Rattus norvegicus)	BDBM50178141 ((S)-1-(2-amino-2-carboxyethyl)-3-(4-carboxybenzyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	9.25E+3	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Antagonist activity against GLUK5-containing kainate receptor by inhibition of kainate-induced depolarization of neonatal rat dorsal root fibers				J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76
University Walk Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%