Affinity Data by PubMed id=17411026

PubMed code 17411026

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476276 (CHEMBL390561) Show SMILES CN(C)c1ccc(\C=C\c2cnc(OCCO)c(Br)c2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476283 (CHEMBL227921) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476279 (CHEMBL227817) Show SMILES CNc1ccc(\C=C\c2cnc(OCCO)c(Br)c2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476277 (CHEMBL1162947) Show SMILES OCCOc1ncc(\C=C/c2ccc(O)cc2)cc1Br Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476284 (CHEMBL227869) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476280 (CHEMBL224148) Show SMILES CN(C)c1ccc(\C=C\c2cnc(OCCO)c(I)c2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476282 (CHEMBL227750) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476278 (CHEMBL224149) Show SMILES CNc1ccc(\C=C\c2cnc(OCCO)c(I)c2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476274 (CHEMBL224147) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476275 (CHEMBL226662) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476281 (CHEMBL227923) Show SMILES OCCOc1ncc(\C=C\c2ccc(O)cc2)cc1I Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50476273 (CHEMBL228094) Show SMILES Oc1ccc(\C=C\c2cnc(OCCOCCOCCF)c(I)c2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain				J Med Chem 50: 2157-65 (2007) Article DOI: 10.1021/jm070025+ BindingDB Entry DOI: 10.7270/Q21N83WD
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%