BindingDB logo
myBDB logout

PubMed code 17764163

Compile data set for download or QSAR
Found 61 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220345
PNG
((+/-)-oxiran-2-ylmethyl (9Z,12Z,15Z)-octadeca-9,12...)
Show SMILES CC\C=C/C\C=C/C\C=C/CCCCCCCC(=O)OCC1CO1 |w:21.20|
Show InChI InChI=1S/C21H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(22)24-19-20-18-23-20/h3-4,6-7,9-10,20H,2,5,8,11-19H2,1H3/b4-3-,7-6-,10-9-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220359
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl benzoate | CH...)
Show SMILES O=C(OCC1CCCCO1)c1ccccc1 |w:4.3|
Show InChI InChI=1S/C13H16O3/c14-13(11-6-2-1-3-7-11)16-10-12-8-4-5-9-15-12/h1-3,6-7,12H,4-5,8-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220351
PNG
((S,5Z,8Z,11Z,14Z)-N-((tetrahydrofuran-2-yl)methyl)...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NC[C@@H]1CCCO1
Show InChI InChI=1S/C25H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-25(27)26-23-24-20-19-22-28-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3,(H,26,27)/b7-6-,10-9-,13-12-,16-15-/t24-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.50E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220347
PNG
((+/-)-oxiran-2-ylmethyl (5Z,8Z,11Z,14Z)-icosa-5,8,...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CO1 |w:23.22|
Show InChI InChI=1S/C23H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(24)26-21-22-20-25-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220342
PNG
(CHEMBL230760 | tetrahydro-2H-pyran-4-yl (5Z,8Z,11Z...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC1CCOCC1
Show InChI InChI=1S/C25H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-25(26)28-24-20-22-27-23-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3/b7-6-,10-9-,13-12-,16-15-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.30E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220352
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl (5Z,8Z,11Z,14...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CCCCO1 |w:23.22|
Show InChI InChI=1S/C26H42O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22-26(27)29-24-25-21-19-20-23-28-25/h6-7,9-10,12-13,15-16,25H,2-5,8,11,14,17-24H2,1H3/b7-6-,10-9-,13-12-,16-15-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.60E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220360
PNG
((R,5Z,8Z,11Z,14Z)-oxiran-2-ylmethyl icosa-5,8,11,1...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@H]1CO1
Show InChI InChI=1S/C23H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(24)26-21-22-20-25-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/t22-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220360
PNG
((R,5Z,8Z,11Z,14Z)-oxiran-2-ylmethyl icosa-5,8,11,1...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@H]1CO1
Show InChI InChI=1S/C23H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(24)26-21-22-20-25-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/t22-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.30E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220343
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl (9Z,12Z)-octa...)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)OCC1CCCCO1 |w:21.20|
Show InChI InChI=1S/C24H42O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-24(25)27-22-23-19-17-18-21-26-23/h6-7,9-10,23H,2-5,8,11-22H2,1H3/b7-6-,10-9-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.50E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220349
PNG
((S,5Z,8Z,11Z,14Z)-oxiran-2-ylmethyl icosa-5,8,11,1...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@@H]1CO1
Show InChI InChI=1S/C23H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(24)26-21-22-20-25-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/t22-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220357
PNG
((+/-)-oxiran-2-ylmethyl (9Z)-hexadec-9-enoate | CH...)
Show SMILES CCCCCC\C=C/CCCCCCCC(=O)OCC1CO1 |w:19.18|
Show InChI InChI=1S/C19H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(20)22-17-18-16-21-18/h7-8,18H,2-6,9-17H2,1H3/b8-7-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.20E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220363
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl (9Z)-hexadec-...)
Show SMILES CCCCCC\C=C/CCCCCCCC(=O)OCC1CCCCO1 |w:19.18|
Show InChI InChI=1S/C22H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18-22(23)25-20-21-17-15-16-19-24-21/h7-8,21H,2-6,9-20H2,1H3/b8-7-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220355
PNG
((+/-)-oxiran-2-ylmethyl (9Z,12Z)-octadeca-9,12-die...)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)OCC1CO1 |w:21.20|
Show InChI InChI=1S/C21H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(22)24-19-20-18-23-20/h6-7,9-10,20H,2-5,8,11-19H2,1H3/b7-6-,10-9-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220353
PNG
((+/-)-oxiran-2-ylmethyl (9Z)-octadec-9-enoate | CH...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OCC1CO1 |w:21.20|
Show InChI InChI=1S/C21H38O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(22)24-19-20-18-23-20/h9-10,20H,2-8,11-19H2,1H3/b10-9-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220345
PNG
((+/-)-oxiran-2-ylmethyl (9Z,12Z,15Z)-octadeca-9,12...)
Show SMILES CC\C=C/C\C=C/C\C=C/CCCCCCCC(=O)OCC1CO1 |w:21.20|
Show InChI InChI=1S/C21H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(22)24-19-20-18-23-20/h3-4,6-7,9-10,20H,2,5,8,11-19H2,1H3/b4-3-,7-6-,10-9-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50107604
PNG
((5Z,8Z,11Z,14Z)-(tetrahydrofuran-3-yl)methyl icosa...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CCOC1
Show InChI InChI=1S/C25H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-25(26)28-23-24-20-21-27-22-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3/b7-6-,10-9-,13-12-,16-15-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.10E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220349
PNG
((S,5Z,8Z,11Z,14Z)-oxiran-2-ylmethyl icosa-5,8,11,1...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@@H]1CO1
Show InChI InChI=1S/C23H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(24)26-21-22-20-25-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/t22-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220347
PNG
((+/-)-oxiran-2-ylmethyl (5Z,8Z,11Z,14Z)-icosa-5,8,...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CO1 |w:23.22|
Show InChI InChI=1S/C23H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(24)26-21-22-20-25-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220357
PNG
((+/-)-oxiran-2-ylmethyl (9Z)-hexadec-9-enoate | CH...)
Show SMILES CCCCCC\C=C/CCCCCCCC(=O)OCC1CO1 |w:19.18|
Show InChI InChI=1S/C19H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(20)22-17-18-16-21-18/h7-8,18H,2-6,9-17H2,1H3/b8-7-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.30E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220358
PNG
((+/-)-(5Z,8Z,11Z,14Z)-N-((2,2-dimethyl-1,3-dioxola...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCC1COC(C)(C)O1 |w:23.22|
Show InChI InChI=1S/C26H43NO3/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(28)27-22-24-23-29-26(2,3)30-24/h8-9,11-12,14-15,17-18,24H,4-7,10,13,16,19-23H2,1-3H3,(H,27,28)/b9-8-,12-11-,15-14-,18-17-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.50E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220354
PNG
((S,5Z,8Z,11Z,14Z)-(2,2-dimethyl-1,3-dioxolan-4-yl)...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@@H]1COC(C)(C)O1
Show InChI InChI=1S/C26H42O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(27)28-22-24-23-29-26(2,3)30-24/h8-9,11-12,14-15,17-18,24H,4-7,10,13,16,19-23H2,1-3H3/b9-8-,12-11-,15-14-,18-17-/t24-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220368
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl 1,1'-biphenyl...)
Show SMILES O=C(OCC1CCCCO1)c1cccc(c1)-c1ccccc1 |w:4.3|
Show InChI InChI=1S/C19H20O3/c20-19(22-14-18-11-4-5-12-21-18)17-10-6-9-16(13-17)15-7-2-1-3-8-15/h1-3,6-10,13,18H,4-5,11-12,14H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220362
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl (9Z,12Z,15Z)-...)
Show SMILES CC\C=C/C\C=C/C\C=C/CCCCCCCC(=O)OCC1CCCCO1 |w:21.20|
Show InChI InChI=1S/C24H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-24(25)27-22-23-19-17-18-21-26-23/h3-4,6-7,9-10,23H,2,5,8,11-22H2,1H3/b4-3-,7-6-,10-9-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220347
PNG
((+/-)-oxiran-2-ylmethyl (5Z,8Z,11Z,14Z)-icosa-5,8,...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CO1 |w:23.22|
Show InChI InChI=1S/C23H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(24)26-21-22-20-25-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.90E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum membrane fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220344
PNG
(2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl (5Z,8Z,11Z,1...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCCC1OCC(C)(C)CO1
Show InChI InChI=1S/C28H46O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-26(29)30-23-22-27-31-24-28(2,3)25-32-27/h8-9,11-12,14-15,17-18,27H,4-7,10,13,16,19-25H2,1-3H3/b9-8-,12-11-,15-14-,18-17-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.10E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50107600
PNG
((5Z,8Z,11Z,14Z)-(tetrahydrofuran-2-yl)methyl icosa...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CCCO1
Show InChI InChI=1S/C25H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-25(26)28-23-24-20-19-22-27-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3/b7-6-,10-9-,13-12-,16-15-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.10E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220362
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl (9Z,12Z,15Z)-...)
Show SMILES CC\C=C/C\C=C/C\C=C/CCCCCCCC(=O)OCC1CCCCO1 |w:21.20|
Show InChI InChI=1S/C24H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-24(25)27-22-23-19-17-18-21-26-23/h3-4,6-7,9-10,23H,2,5,8,11-22H2,1H3/b4-3-,7-6-,10-9-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220355
PNG
((+/-)-oxiran-2-ylmethyl (9Z,12Z)-octadeca-9,12-die...)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)OCC1CO1 |w:21.20|
Show InChI InChI=1S/C21H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(22)24-19-20-18-23-20/h6-7,9-10,20H,2-5,8,11-19H2,1H3/b7-6-,10-9-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.30E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220356
PNG
((R,5Z,8Z,11Z,14Z)-N-((tetrahydrofuran-2-yl)methyl)...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NC[C@H]1CCCO1
Show InChI InChI=1S/C25H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-25(27)26-23-24-20-19-22-28-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3,(H,26,27)/b7-6-,10-9-,13-12-,16-15-/t24-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220352
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl (5Z,8Z,11Z,14...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CCCCO1 |w:23.22|
Show InChI InChI=1S/C26H42O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22-26(27)29-24-25-21-19-20-23-28-25/h6-7,9-10,12-13,15-16,25H,2-5,8,11,14,17-24H2,1H3/b7-6-,10-9-,13-12-,16-15-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.60E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum membrane fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220344
PNG
(2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl (5Z,8Z,11Z,1...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCCC1OCC(C)(C)CO1
Show InChI InChI=1S/C28H46O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-26(29)30-23-22-27-31-24-28(2,3)25-32-27/h8-9,11-12,14-15,17-18,27H,4-7,10,13,16,19-25H2,1-3H3/b9-8-,12-11-,15-14-,18-17-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.70E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220364
PNG
((R,5Z,8Z,11Z,14Z)-(2,2-dimethyl-1,3-dioxolan-4-yl)...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@H]1COC(C)(C)O1
Show InChI InChI=1S/C26H42O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(27)28-22-24-23-29-26(2,3)30-24/h8-9,11-12,14-15,17-18,24H,4-7,10,13,16,19-23H2,1-3H3/b9-8-,12-11-,15-14-,18-17-/t24-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.80E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220357
PNG
((+/-)-oxiran-2-ylmethyl (9Z)-hexadec-9-enoate | CH...)
Show SMILES CCCCCC\C=C/CCCCCCCC(=O)OCC1CO1 |w:19.18|
Show InChI InChI=1S/C19H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(20)22-17-18-16-21-18/h7-8,18H,2-6,9-17H2,1H3/b8-7-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.80E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum membrane fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220365
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl (9Z)-octadec-...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OCC1CCCCO1 |w:21.20|
Show InChI InChI=1S/C24H44O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-24(25)27-22-23-19-17-18-21-26-23/h9-10,23H,2-8,11-22H2,1H3/b10-9-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.90E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220342
PNG
(CHEMBL230760 | tetrahydro-2H-pyran-4-yl (5Z,8Z,11Z...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC1CCOCC1
Show InChI InChI=1S/C25H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-25(26)28-24-20-22-27-23-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3/b7-6-,10-9-,13-12-,16-15-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220361
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl 1,1'-biphenyl...)
Show SMILES O=C(OCC1CCCCO1)c1ccc(cc1)-c1ccccc1 |w:4.3|
Show InChI InChI=1S/C19H20O3/c20-19(22-14-18-8-4-5-13-21-18)17-11-9-16(10-12-17)15-6-2-1-3-7-15/h1-3,6-7,9-12,18H,4-5,8,13-14H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.20E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50107600
PNG
((5Z,8Z,11Z,14Z)-(tetrahydrofuran-2-yl)methyl icosa...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CCCO1
Show InChI InChI=1S/C25H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-25(26)28-23-24-20-19-22-27-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3/b7-6-,10-9-,13-12-,16-15-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.30E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50107601
PNG
((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid (t...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCC1CCCO1
Show InChI InChI=1S/C25H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-25(27)26-23-24-20-19-22-28-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3,(H,26,27)/b7-6-,10-9-,13-12-,16-15-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.40E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220366
PNG
((+/-)-oxiran-2-ylmethyl 1,1'-biphenyl-4-carboxylat...)
Show SMILES O=C(OCC1CO1)c1ccc(cc1)-c1ccccc1 |w:4.3|
Show InChI InChI=1S/C16H14O3/c17-16(19-11-15-10-18-15)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9,15H,10-11H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.50E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50107604
PNG
((5Z,8Z,11Z,14Z)-(tetrahydrofuran-3-yl)methyl icosa...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CCOC1
Show InChI InChI=1S/C25H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-25(26)28-23-24-20-21-27-22-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3/b7-6-,10-9-,13-12-,16-15-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.30E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220346
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl 1,1'-biphenyl...)
Show SMILES O=C(OCC1CCCCO1)c1ccccc1-c1ccccc1 |w:4.3|
Show InChI InChI=1S/C19H20O3/c20-19(22-14-16-10-6-7-13-21-16)18-12-5-4-11-17(18)15-8-2-1-3-9-15/h1-5,8-9,11-12,16H,6-7,10,13-14H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.30E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220350
PNG
(1,3-benzodioxol-5-ylmethyl (5Z,8Z,11Z,14Z)-icosa-5...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCc1ccc2OCOc2c1
Show InChI InChI=1S/C28H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(29)30-23-25-20-21-26-27(22-25)32-24-31-26/h6-7,9-10,12-13,15-16,20-22H,2-5,8,11,14,17-19,23-24H2,1H3/b7-6-,10-9-,13-12-,16-15-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.50E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220348
PNG
((+/-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl (5Z,8Z,...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1COC(C)(C)O1 |w:23.22|
Show InChI InChI=1S/C26H42O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(27)28-22-24-23-29-26(2,3)30-24/h8-9,11-12,14-15,17-18,24H,4-7,10,13,16,19-23H2,1-3H3/b9-8-,12-11-,15-14-,18-17-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.50E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220345
PNG
((+/-)-oxiran-2-ylmethyl (9Z,12Z,15Z)-octadeca-9,12...)
Show SMILES CC\C=C/C\C=C/C\C=C/CCCCCCCC(=O)OCC1CO1 |w:21.20|
Show InChI InChI=1S/C21H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(22)24-19-20-18-23-20/h3-4,6-7,9-10,20H,2,5,8,11-19H2,1H3/b4-3-,7-6-,10-9-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.00E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum membrane fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220352
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl (5Z,8Z,11Z,14...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CCCCO1 |w:23.22|
Show InChI InChI=1S/C26H42O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22-26(27)29-24-25-21-19-20-23-28-25/h6-7,9-10,12-13,15-16,25H,2-5,8,11,14,17-24H2,1H3/b7-6-,10-9-,13-12-,16-15-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.10E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220359
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl benzoate | CH...)
Show SMILES O=C(OCC1CCCCO1)c1ccccc1 |w:4.3|
Show InChI InChI=1S/C13H16O3/c14-13(11-6-2-1-3-7-11)16-10-12-8-4-5-9-15-12/h1-3,6-7,12H,4-5,8-10H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 5.30E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50107601
PNG
((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid (t...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCC1CCCO1
Show InChI InChI=1S/C25H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-25(27)26-23-24-20-19-22-28-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3,(H,26,27)/b7-6-,10-9-,13-12-,16-15-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.60E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220364
PNG
((R,5Z,8Z,11Z,14Z)-(2,2-dimethyl-1,3-dioxolan-4-yl)...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@H]1COC(C)(C)O1
Show InChI InChI=1S/C26H42O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(27)28-22-24-23-29-26(2,3)30-24/h8-9,11-12,14-15,17-18,24H,4-7,10,13,16,19-23H2,1-3H3/b9-8-,12-11-,15-14-,18-17-/t24-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.00E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220367
PNG
((+/-)-oxiran-2-ylmethyl 1,1'-biphenyl-3-carboxylat...)
Show SMILES O=C(OCC1CO1)c1cccc(c1)-c1ccccc1 |w:4.3|
Show InChI InChI=1S/C16H14O3/c17-16(19-11-15-10-18-15)14-8-4-7-13(9-14)12-5-2-1-3-6-12/h1-9,15H,10-11H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.10E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220351
PNG
((S,5Z,8Z,11Z,14Z)-N-((tetrahydrofuran-2-yl)methyl)...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NC[C@@H]1CCCO1
Show InChI InChI=1S/C25H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-25(27)26-23-24-20-19-22-28-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3,(H,26,27)/b7-6-,10-9-,13-12-,16-15-/t24-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.90E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220351
PNG
((S,5Z,8Z,11Z,14Z)-N-((tetrahydrofuran-2-yl)methyl)...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NC[C@@H]1CCCO1
Show InChI InChI=1S/C25H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-25(27)26-23-24-20-19-22-28-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3,(H,26,27)/b7-6-,10-9-,13-12-,16-15-/t24-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.00E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum membrane fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220343
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl (9Z,12Z)-octa...)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)OCC1CCCCO1 |w:21.20|
Show InChI InChI=1S/C24H42O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-24(25)27-22-23-19-17-18-21-26-23/h6-7,9-10,23H,2-5,8,11-22H2,1H3/b7-6-,10-9-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.30E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50107600
PNG
((5Z,8Z,11Z,14Z)-(tetrahydrofuran-2-yl)methyl icosa...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CCCO1
Show InChI InChI=1S/C25H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-25(26)28-23-24-20-19-22-27-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3/b7-6-,10-9-,13-12-,16-15-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.50E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum membrane fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220361
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl 1,1'-biphenyl...)
Show SMILES O=C(OCC1CCCCO1)c1ccc(cc1)-c1ccccc1 |w:4.3|
Show InChI InChI=1S/C19H20O3/c20-19(22-14-18-8-4-5-13-21-18)17-11-9-16(10-12-17)15-6-2-1-3-7-15/h1-3,6-7,9-12,18H,4-5,8,13-14H2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.00E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum membrane fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220356
PNG
((R,5Z,8Z,11Z,14Z)-N-((tetrahydrofuran-2-yl)methyl)...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NC[C@H]1CCCO1
Show InChI InChI=1S/C25H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-25(27)26-23-24-20-19-22-28-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3,(H,26,27)/b7-6-,10-9-,13-12-,16-15-/t24-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.10E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum membrane fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220358
PNG
((+/-)-(5Z,8Z,11Z,14Z)-N-((2,2-dimethyl-1,3-dioxola...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCC1COC(C)(C)O1 |w:23.22|
Show InChI InChI=1S/C26H43NO3/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(28)27-22-24-23-29-26(2,3)30-24/h8-9,11-12,14-15,17-18,24H,4-7,10,13,16,19-23H2,1-3H3,(H,27,28)/b9-8-,12-11-,15-14-,18-17-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.00E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220350
PNG
(1,3-benzodioxol-5-ylmethyl (5Z,8Z,11Z,14Z)-icosa-5...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCc1ccc2OCOc2c1
Show InChI InChI=1S/C28H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(29)30-23-25-20-21-26-27(22-25)32-24-31-26/h6-7,9-10,12-13,15-16,20-22H,2-5,8,11,14,17-19,23-24H2,1H3/b7-6-,10-9-,13-12-,16-15-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.10E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220348
PNG
((+/-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl (5Z,8Z,...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1COC(C)(C)O1 |w:23.22|
Show InChI InChI=1S/C26H42O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(27)28-22-24-23-29-26(2,3)30-24/h8-9,11-12,14-15,17-18,24H,4-7,10,13,16,19-23H2,1-3H3/b9-8-,12-11-,15-14-,18-17-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.50E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum membrane fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220348
PNG
((+/-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl (5Z,8Z,...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1COC(C)(C)O1 |w:23.22|
Show InChI InChI=1S/C26H42O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(27)28-22-24-23-29-26(2,3)30-24/h8-9,11-12,14-15,17-18,24H,4-7,10,13,16,19-23H2,1-3H3/b9-8-,12-11-,15-14-,18-17-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.80E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))		BDBM50220356
PNG
((R,5Z,8Z,11Z,14Z)-N-((tetrahydrofuran-2-yl)methyl)...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NC[C@H]1CCCO1
Show InChI InChI=1S/C25H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-25(27)26-23-24-20-19-22-28-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3,(H,26,27)/b7-6-,10-9-,13-12-,16-15-/t24-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.90E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase


(Rattus norvegicus (Rat))		BDBM50220344
PNG
(2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl (5Z,8Z,11Z,1...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCCC1OCC(C)(C)CO1
Show InChI InChI=1S/C28H46O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-26(29)30-23-22-27-31-24-28(2,3)25-32-27/h8-9,11-12,14-15,17-18,27H,4-7,10,13,16,19-25H2,1-3H3/b9-8-,12-11-,15-14-,18-17-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.90E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum membrane fractions assessed as [3H]-2-oleoglycerol hydrolysis

J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%