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PubMed code 17927165

Compile data set for download or QSAR
Found 58 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19331
PNG
(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 |r|
Show InChI InChI=1S/C36H39N7O2/c1-45-28-13-10-24(11-14-28)23-43-34(15-12-26-21-38-31-8-4-2-6-29(26)31)41-42-35(43)33(40-36(44)25-16-18-37-19-17-25)20-27-22-39-32-9-5-3-7-30(27)32/h2-11,13-14,21-22,25,33,37-39H,12,15-20,23H2,1H3,(H,40,44)/t33-/m1/s1
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n/an/a 0.300n/a 3n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19333
PNG
(N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-[2-(1...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)c(OC)c1 |r|
Show InChI InChI=1S/C37H41N7O3/c1-46-28-13-11-26(34(20-28)47-2)23-44-35(14-12-25-21-39-31-9-5-3-7-29(25)31)42-43-36(44)33(41-37(45)24-15-17-38-18-16-24)19-27-22-40-32-10-6-4-8-30(27)32/h3-11,13,20-22,24,33,38-40H,12,14-19,23H2,1-2H3,(H,41,45)/t33-/m1/s1
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n/an/a 0.5n/a 0.600n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19332
PNG
(N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)m...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 |r|
Show InChI InChI=1S/C34H38N6O2/c1-42-28-14-11-25(12-15-28)23-40-32(16-13-24-7-3-2-4-8-24)38-39-33(40)31(37-34(41)26-17-19-35-20-18-26)21-27-22-36-30-10-6-5-9-29(27)30/h2-12,14-15,22,26,31,35-36H,13,16-21,23H2,1H3,(H,37,41)/t31-/m1/s1
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n/an/a 0.600n/a 1.60n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19334
PNG
(N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-(2-ph...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)c(OC)c1 |r|
Show InChI InChI=1S/C35H40N6O3/c1-43-28-14-13-26(32(21-28)44-2)23-41-33(15-12-24-8-4-3-5-9-24)39-40-34(41)31(38-35(42)25-16-18-36-19-17-25)20-27-22-37-30-11-7-6-10-29(27)30/h3-11,13-14,21-22,25,31,36-37H,12,15-20,23H2,1-2H3,(H,38,42)/t31-/m1/s1
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n/an/a 0.900n/a 6.10n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19312
PNG
((2S)-N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)c(OC)c1 |r|
Show InChI InChI=1S/C36H39N7O3/c1-45-26-15-13-24(33(19-26)46-2)22-43-34(16-14-23-20-38-29-10-5-3-8-27(23)29)41-42-35(43)32(40-36(44)31-12-7-17-37-31)18-25-21-39-30-11-6-4-9-28(25)30/h3-6,8-11,13,15,19-21,31-32,37-39H,7,12,14,16-18,22H2,1-2H3,(H,40,44)/t31-,32+/m0/s1
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n/an/a 5.60 11n/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19294
PNG
(2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indo...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)cc1 |r|
Show InChI InChI=1S/C34H37N7O2/c1-34(2,35)33(42)38-30(18-24-20-37-29-11-7-5-9-27(24)29)32-40-39-31(41(32)21-22-12-15-25(43-3)16-13-22)17-14-23-19-36-28-10-6-4-8-26(23)28/h4-13,15-16,19-20,30,36-37H,14,17-18,21,35H2,1-3H3,(H,38,42)/t30-/m1/s1
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n/an/a 6 4n/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19349
PNG
(N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)m...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCOCC2)cc1 |r|
Show InChI InChI=1S/C34H37N5O3/c1-41-28-14-11-25(12-15-28)23-39-32(16-13-24-7-3-2-4-8-24)37-38-33(39)31(36-34(40)26-17-19-42-20-18-26)21-27-22-35-30-10-6-5-9-29(27)30/h2-12,14-15,22,26,31,35H,13,16-21,23H2,1H3,(H,36,40)/t31-/m1/s1
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n/an/a 6 51n/an/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19318
PNG
(N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-[2-(1...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCCNC2)c(OC)c1 |r|
Show InChI InChI=1S/C37H41N7O3/c1-46-28-15-13-26(34(19-28)47-2)23-44-35(16-14-24-21-39-31-11-5-3-9-29(24)31)42-43-36(44)33(41-37(45)25-8-7-17-38-20-25)18-27-22-40-32-12-6-4-10-30(27)32/h3-6,9-13,15,19,21-22,25,33,38-40H,7-8,14,16-18,20,23H2,1-2H3,(H,41,45)/t25?,33-/m1/s1
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n/an/a 6.5n/a 5.30n/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19323
PNG
((3R)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphe...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCNC2)cc1 |r|
Show InChI InChI=1S/C34H38N6O2/c1-42-28-16-13-25(14-17-28)23-40-32(18-15-24-8-3-2-4-9-24)38-39-33(40)31(37-34(41)26-10-7-19-35-21-26)20-27-22-36-30-12-6-5-11-29(27)30/h2-6,8-9,11-14,16-17,22,26,31,35-36H,7,10,15,18-21,23H2,1H3,(H,37,41)/t26-,31-/m1/s1
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n/an/a 7n/a 36n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19308
PNG
((2S)-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)cc1 |r|
Show InChI InChI=1S/C35H37N7O2/c1-44-26-15-12-23(13-16-26)22-42-33(17-14-24-20-37-29-9-4-2-7-27(24)29)40-41-34(42)32(39-35(43)31-11-6-18-36-31)19-25-21-38-30-10-5-3-8-28(25)30/h2-5,7-10,12-13,15-16,20-21,31-32,36-38H,6,11,14,17-19,22H2,1H3,(H,39,43)/t31-,32+/m0/s1
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n/an/a 9 6n/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19310
PNG
((2S)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphe...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)cc1 |r|
Show InChI InChI=1S/C33H36N6O2/c1-41-26-16-13-24(14-17-26)22-39-31(18-15-23-8-3-2-4-9-23)37-38-32(39)30(36-33(40)29-12-7-19-34-29)20-25-21-35-28-11-6-5-10-27(25)28/h2-6,8-11,13-14,16-17,21,29-30,34-35H,7,12,15,18-20,22H2,1H3,(H,36,40)/t29-,30+/m0/s1
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n/an/a 9.5 13n/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19321
PNG
((3S)-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCNC2)cc1 |r|
Show InChI InChI=1S/C36H39N7O2/c1-45-28-15-12-24(13-16-28)23-43-34(17-14-25-21-38-31-10-4-2-8-29(25)31)41-42-35(43)33(40-36(44)26-7-6-18-37-20-26)19-27-22-39-32-11-5-3-9-30(27)32/h2-5,8-13,15-16,21-22,26,33,37-39H,6-7,14,17-20,23H2,1H3,(H,40,44)/t26-,33+/m0/s1
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n/an/a 10n/a 2.5n/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19326
PNG
((2S)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphe...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCCN2)cc1 |r|
Show InChI InChI=1S/C34H38N6O2/c1-42-27-17-14-25(15-18-27)23-40-32(19-16-24-9-3-2-4-10-24)38-39-33(40)31(37-34(41)30-13-7-8-20-35-30)21-26-22-36-29-12-6-5-11-28(26)29/h2-6,9-12,14-15,17-18,22,30-31,35-36H,7-8,13,16,19-21,23H2,1H3,(H,37,41)/t30-,31+/m0/s1
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n/an/a 11 27n/an/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19319
PNG
(N-[(1R)-1-{4-benzyl-5-[2-(1H-indol-3-yl)ethyl]-4H-...)
Show SMILES O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2c[nH]c3ccccc23)n1Cc1ccccc1)C1CCCNC1 |r|
Show InChI InChI=1S/C35H37N7O/c43-35(26-11-8-18-36-20-26)39-32(19-27-22-38-31-15-7-5-13-29(27)31)34-41-40-33(42(34)23-24-9-2-1-3-10-24)17-16-25-21-37-30-14-6-4-12-28(25)30/h1-7,9-10,12-15,21-22,26,32,36-38H,8,11,16-20,23H2,(H,39,43)/t26?,32-/m1/s1
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n/an/a 13n/a 9.90n/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19293
PNG
((R)-N-(1-(5-(2-(1H-Indol-3-yl)ethyl)-4-benzyl-4H-1...)
Show SMILES CC(C)(N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2c[nH]c3ccccc23)n1Cc1ccccc1 |r|
Show InChI InChI=1S/C33H35N7O/c1-33(2,34)32(41)37-29(18-24-20-36-28-15-9-7-13-26(24)28)31-39-38-30(40(31)21-22-10-4-3-5-11-22)17-16-23-19-35-27-14-8-6-12-25(23)27/h3-15,19-20,29,35-36H,16-18,21,34H2,1-2H3,(H,37,41)/t29-/m1/s1
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n/an/a 15n/a 64n/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19322
PNG
((3S)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphe...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCNC2)cc1 |r|
Show InChI InChI=1S/C34H38N6O2/c1-42-28-16-13-25(14-17-28)23-40-32(18-15-24-8-3-2-4-9-24)38-39-33(40)31(37-34(41)26-10-7-19-35-21-26)20-27-22-36-30-12-6-5-11-29(27)30/h2-6,8-9,11-14,16-17,22,26,31,35-36H,7,10,15,18-21,23H2,1H3,(H,37,41)/t26-,31+/m0/s1
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n/an/a 16 10n/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19344
PNG
(N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3-yl)e...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CNCCN2)cc1 |r|
Show InChI InChI=1S/C35H38N8O2/c1-45-26-13-10-23(11-14-26)22-43-33(15-12-24-19-38-29-8-4-2-6-27(24)29)41-42-34(43)31(40-35(44)32-21-36-16-17-37-32)18-25-20-39-30-9-5-3-7-28(25)30/h2-11,13-14,19-20,31-32,36-39H,12,15-18,21-22H2,1H3,(H,40,44)/t31-,32?/m1/s1
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n/an/a 18n/a 8.70n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19350
PNG
(N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)m...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCCCC2)cc1 |r|
Show InChI InChI=1S/C35H39N5O2/c1-42-29-19-16-26(17-20-29)24-40-33(21-18-25-10-4-2-5-11-25)38-39-34(40)32(37-35(41)27-12-6-3-7-13-27)22-28-23-36-31-15-9-8-14-30(28)31/h2,4-5,8-11,14-17,19-20,23,27,32,36H,3,6-7,12-13,18,21-22,24H2,1H3,(H,37,41)/t32-/m1/s1
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n/an/a 18n/a 390n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19339
PNG
(N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phenylet...)
Show SMILES CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1 |r|
Show InChI InChI=1S/C35H40N6O/c1-2-25-12-14-27(15-13-25)24-41-33(17-16-26-8-4-3-5-9-26)39-40-34(41)32(38-35(42)28-18-20-36-21-19-28)22-29-23-37-31-11-7-6-10-30(29)31/h3-15,23,28,32,36-37H,2,16-22,24H2,1H3,(H,38,42)/t32-/m1/s1
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n/an/a 19n/a 7.70n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19328
PNG
((2R)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphe...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCCN2)cc1 |r|
Show InChI InChI=1S/C34H38N6O2/c1-42-27-17-14-25(15-18-27)23-40-32(19-16-24-9-3-2-4-10-24)38-39-33(40)31(37-34(41)30-13-7-8-20-35-30)21-26-22-36-29-12-6-5-11-28(26)29/h2-6,9-12,14-15,17-18,22,30-31,35-36H,7-8,13,16,19-21,23H2,1H3,(H,37,41)/t30-,31-/m1/s1
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n/an/a 23 53n/an/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19335
PNG
(N-[(1R)-1-{4-benzyl-5-[2-(1H-indol-3-yl)ethyl]-4H-...)
Show SMILES O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2c[nH]c3ccccc23)n1Cc1ccccc1)C1CCNCC1 |r|
Show InChI InChI=1S/C35H37N7O/c43-35(25-16-18-36-19-17-25)39-32(20-27-22-38-31-13-7-5-11-29(27)31)34-41-40-33(42(34)23-24-8-2-1-3-9-24)15-14-26-21-37-30-12-6-4-10-28(26)30/h1-13,21-22,25,32,36-38H,14-20,23H2,(H,39,43)/t32-/m1/s1
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n/an/a 24n/a 5.40n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19309
PNG
((2R)-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCN2)cc1 |r|
Show InChI InChI=1S/C35H37N7O2/c1-44-26-15-12-23(13-16-26)22-42-33(17-14-24-20-37-29-9-4-2-7-27(24)29)40-41-34(42)32(39-35(43)31-11-6-18-36-31)19-25-21-38-30-10-5-3-8-28(25)30/h2-5,7-10,12-13,15-16,20-21,31-32,36-38H,6,11,14,17-19,22H2,1H3,(H,39,43)/t31-,32-/m1/s1
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n/an/a 28 7n/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19327
PNG
((2R)-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCCN2)cc1 |r|
Show InChI InChI=1S/C36H39N7O2/c1-45-27-16-13-24(14-17-27)23-43-34(18-15-25-21-38-30-10-4-2-8-28(25)30)41-42-35(43)33(40-36(44)32-12-6-7-19-37-32)20-26-22-39-31-11-5-3-9-29(26)31/h2-5,8-11,13-14,16-17,21-22,32-33,37-39H,6-7,12,15,18-20,23H2,1H3,(H,40,44)/t32-,33-/m1/s1
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n/an/a 29 8n/an/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19311
PNG
((2R)-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphe...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCN2)cc1 |r|
Show InChI InChI=1S/C33H36N6O2/c1-41-26-16-13-24(14-17-26)22-39-31(18-15-23-8-3-2-4-9-23)37-38-32(39)30(36-33(40)29-12-7-19-34-29)20-25-21-35-28-11-6-5-10-27(25)28/h2-6,8-11,13-14,16-17,21,29-30,34-35H,7,12,15,18-20,22H2,1H3,(H,36,40)/t29-,30-/m1/s1
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n/an/a 32 8n/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19346
PNG
((R,S)-N-((R)-1-(5-(2-(1H-Indol-3-yl)ethyl)-4-(2,4-...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CNCCN2)c(OC)c1 |r|
Show InChI InChI=1S/C36H40N8O3/c1-46-26-13-11-24(33(18-26)47-2)22-44-34(14-12-23-19-39-29-9-5-3-7-27(23)29)42-43-35(44)31(41-36(45)32-21-37-15-16-38-32)17-25-20-40-30-10-6-4-8-28(25)30/h3-11,13,18-20,31-32,37-40H,12,14-17,21-22H2,1-2H3,(H,41,45)/t31-,32?/m1/s1
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n/an/a 32 5n/an/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19296
PNG
(2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxy...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CN)cc1 |r|
Show InChI InChI=1S/C30H32N6O2/c1-38-24-14-11-22(12-15-24)20-36-28(16-13-21-7-3-2-4-8-21)34-35-30(36)27(33-29(37)18-31)17-23-19-32-26-10-6-5-9-25(23)26/h2-12,14-15,19,27,32H,13,16-18,20,31H2,1H3,(H,33,37)/t27-/m1/s1
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n/an/a 32 19n/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19347
PNG
(N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-(2-ph...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CNCCN2)c(OC)c1 |r|
Show InChI InChI=1S/C34H39N7O3/c1-43-26-14-13-24(31(19-26)44-2)22-41-32(15-12-23-8-4-3-5-9-23)39-40-33(41)29(38-34(42)30-21-35-16-17-36-30)18-25-20-37-28-11-7-6-10-27(25)28/h3-11,13-14,19-20,29-30,35-37H,12,15-18,21-22H2,1-2H3,(H,38,42)/t29-,30?/m1/s1
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n/an/a 35n/a 19.6n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19297
PNG
(2-amino-N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CN)c(OC)c1 |r|
Show InChI InChI=1S/C33H35N7O3/c1-42-24-13-11-22(30(16-24)43-2)20-40-31(14-12-21-18-35-27-9-5-3-7-25(21)27)38-39-33(40)29(37-32(41)17-34)15-23-19-36-28-10-6-4-8-26(23)28/h3-11,13,16,18-19,29,35-36H,12,14-15,17,20,34H2,1-2H3,(H,37,41)/t29-/m1/s1
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n/an/a 38 27n/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19313
PNG
((2S)-N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)c(OC)c1 |r|
Show InChI InChI=1S/C34H38N6O3/c1-42-26-16-15-24(31(20-26)43-2)22-40-32(17-14-23-9-4-3-5-10-23)38-39-33(40)30(37-34(41)29-13-8-18-35-29)19-25-21-36-28-12-7-6-11-27(25)28/h3-7,9-12,15-16,20-21,29-30,35-36H,8,13-14,17-19,22H2,1-2H3,(H,37,41)/t29-,30+/m0/s1
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n/an/a 44 32n/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19325
PNG
(N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-[2-(1...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCCCN2)c(OC)c1 |r|
Show InChI InChI=1S/C37H41N7O3/c1-46-27-16-14-25(34(20-27)47-2)23-44-35(17-15-24-21-39-30-11-5-3-9-28(24)30)42-43-36(44)33(41-37(45)32-13-7-8-18-38-32)19-26-22-40-31-12-6-4-10-29(26)31/h3-6,9-12,14,16,20-22,32-33,38-40H,7-8,13,15,17-19,23H2,1-2H3,(H,41,45)/t32?,33-/m1/s1
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n/an/a 53 18n/an/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19345
PNG
(N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-methoxyphenyl)m...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CNCCN2)cc1 |r|
Show InChI InChI=1S/C33H37N7O2/c1-42-26-14-11-24(12-15-26)22-40-31(16-13-23-7-3-2-4-8-23)38-39-32(40)29(37-33(41)30-21-34-17-18-35-30)19-25-20-36-28-10-6-5-9-27(25)28/h2-12,14-15,20,29-30,34-36H,13,16-19,21-22H2,1H3,(H,37,41)/t29-,30?/m1/s1
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n/an/a 54n/a 12n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19306
PNG
((R)-N-(1-(4-(4-Methoxybenzyl)-5-phenethyl-4H-1,2,4...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CCN)cc1 |r|
Show InChI InChI=1S/C31H34N6O2/c1-39-25-14-11-23(12-15-25)21-37-29(16-13-22-7-3-2-4-8-22)35-36-31(37)28(34-30(38)17-18-32)19-24-20-33-27-10-6-5-9-26(24)27/h2-12,14-15,20,28,33H,13,16-19,21,32H2,1H3,(H,34,38)/t28-/m1/s1
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n/an/a 59n/a 256n/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19340
PNG
(N-[(1R)-1-[4-(2,4-dimethoxyphenyl)-5-(2-phenylethy...)
Show SMILES COc1ccc(c(OC)c1)-n1c(CCc2ccccc2)nnc1[C@@H](Cc1c[nH]c2ccccc12)NC(=O)C1CCNCC1 |r,wU:23.38,(4.57,-2.49,;3.09,-2.1,;2.48,-.68,;.95,-.51,;.33,.91,;1.25,2.14,;2.78,1.97,;3.7,3.2,;5.24,3.2,;3.39,.55,;.85,3.63,;2.12,4.51,;3.57,4,;4.74,5.01,;4.74,6.55,;3.4,7.32,;3.4,8.86,;4.74,9.63,;6.07,8.86,;6.07,7.32,;1.67,5.98,;.13,6.02,;-.37,4.56,;-1.71,3.79,;-2.48,2.46,;-2.48,.92,;-1,.49,;-.95,-1.05,;-2.41,-1.57,;-2.99,-3,;-4.52,-3.2,;-5.46,-1.98,;-4.87,-.56,;-3.35,-.35,;-3.04,4.56,;-4.38,3.79,;-4.38,2.25,;-5.71,4.56,;-7.04,3.79,;-8.38,4.56,;-8.38,6.1,;-7.04,6.87,;-5.71,6.1,)|
Show InChI InChI=1S/C34H38N6O3/c1-42-26-13-14-30(31(21-26)43-2)40-32(15-12-23-8-4-3-5-9-23)38-39-33(40)29(37-34(41)24-16-18-35-19-17-24)20-25-22-36-28-11-7-6-10-27(25)28/h3-11,13-14,21-22,24,29,35-36H,12,15-20H2,1-2H3,(H,37,41)/t29-/m1/s1
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n/an/a 63n/a 14n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19337
PNG
(N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indol-3-yl)e...)
Show SMILES O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2c[nH]c3ccccc23)n1-c1ccccc1)C1CCNCC1 |r|
Show InChI InChI=1S/C34H35N7O/c42-34(23-16-18-35-19-17-23)38-31(20-25-22-37-30-13-7-5-11-28(25)30)33-40-39-32(41(33)26-8-2-1-3-9-26)15-14-24-21-36-29-12-6-4-10-27(24)29/h1-13,21-23,31,35-37H,14-20H2,(H,38,42)/t31-/m1/s1
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n/an/a 70n/a 2.30n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19338
PNG
(N-[(1R)-1-[4-(4-ethylphenyl)-5-[2-(1H-indol-3-yl)e...)
Show SMILES CCc1ccc(cc1)-n1c(CCc2c[nH]c3ccccc23)nnc1[C@@H](Cc1c[nH]c2ccccc12)NC(=O)C1CCNCC1 |r|
Show InChI InChI=1S/C36H39N7O/c1-2-24-11-14-28(15-12-24)43-34(16-13-26-22-38-31-9-5-3-7-29(26)31)41-42-35(43)33(40-36(44)25-17-19-37-20-18-25)21-27-23-39-32-10-6-4-8-30(27)32/h3-12,14-15,22-23,25,33,37-39H,2,13,16-21H2,1H3,(H,40,44)/t33-/m1/s1
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n/an/a 96n/a 15n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19304
PNG
((2S)-2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-me...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)N)cc1 |r|
Show InChI InChI=1S/C31H34N6O2/c1-21(32)31(38)34-28(18-24-19-33-27-11-7-6-10-26(24)27)30-36-35-29(17-14-22-8-4-3-5-9-22)37(30)20-23-12-15-25(39-2)16-13-23/h3-13,15-16,19,21,28,33H,14,17-18,20,32H2,1-2H3,(H,34,38)/t21-,28+/m0/s1
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n/an/a 113n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19324
PNG
((3S)-N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phe...)
Show SMILES CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCNC2)cc1 |r|
Show InChI InChI=1S/C35H40N6O/c1-2-25-14-16-27(17-15-25)24-41-33(19-18-26-9-4-3-5-10-26)39-40-34(41)32(38-35(42)28-11-8-20-36-22-28)21-29-23-37-31-13-7-6-12-30(29)31/h3-7,9-10,12-17,23,28,32,36-37H,2,8,11,18-22,24H2,1H3,(H,38,42)/t28-,32+/m0/s1
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n/an/a 130n/an/an/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19329
PNG
((2R)-N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]-5-...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCCN2)c(OC)c1 |r|
Show InChI InChI=1S/C35H40N6O3/c1-43-27-17-16-25(32(21-27)44-2)23-41-33(18-15-24-10-4-3-5-11-24)39-40-34(41)31(38-35(42)30-14-8-9-19-36-30)20-26-22-37-29-13-7-6-12-28(26)29/h3-7,10-13,16-17,21-22,30-31,36-37H,8-9,14-15,18-20,23H2,1-2H3,(H,38,42)/t30-,31-/m1/s1
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n/an/a 134n/an/an/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19295
PNG
(2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(1H-indo...)
Show SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CN)cc1 |r|
Show InChI InChI=1S/C32H33N7O2/c1-41-24-13-10-21(11-14-24)20-39-30(15-12-22-18-34-27-8-4-2-6-25(22)27)37-38-32(39)29(36-31(40)17-33)16-23-19-35-28-9-5-3-7-26(23)28/h2-11,13-14,18-19,29,34-35H,12,15-17,20,33H2,1H3,(H,36,40)/t29-/m1/s1
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n/an/a 138n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19298
PNG
(2-amino-N-[(1R)-1-{4-[(2,4-dimethoxyphenyl)methyl]...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CN)c(OC)c1 |r|
Show InChI InChI=1S/C31H34N6O3/c1-39-24-14-13-22(28(17-24)40-2)20-37-29(15-12-21-8-4-3-5-9-21)35-36-31(37)27(34-30(38)18-32)16-23-19-33-26-11-7-6-10-25(23)26/h3-11,13-14,17,19,27,33H,12,15-16,18,20,32H2,1-2H3,(H,34,38)/t27-/m1/s1
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n/an/a 154n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19317
PNG
((2S,4R)-4-hydroxy-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2C[C@@H](O)CN2)cc1 |r|
Show InChI InChI=1S/C33H36N6O3/c1-42-26-14-11-23(12-15-26)21-39-31(16-13-22-7-3-2-4-8-22)37-38-32(39)29(36-33(41)30-18-25(40)20-35-30)17-24-19-34-28-10-6-5-9-27(24)28/h2-12,14-15,19,25,29-30,34-35,40H,13,16-18,20-21H2,1H3,(H,36,41)/t25-,29-,30+/m1/s1
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n/an/a 173n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19307
PNG
((2S)-2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-{4-[(4-me...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](N)Cc2ccccc2)cc1 |r|
Show InChI InChI=1S/C37H38N6O2/c1-45-30-19-16-28(17-20-30)25-43-35(21-18-26-10-4-2-5-11-26)41-42-36(43)34(23-29-24-39-33-15-9-8-14-31(29)33)40-37(44)32(38)22-27-12-6-3-7-13-27/h2-17,19-20,24,32,34,39H,18,21-23,25,38H2,1H3,(H,40,44)/t32-,34+/m0/s1
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n/an/a 175 24n/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19348
PNG
(N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phenylet...)
Show SMILES CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CNCCN2)cc1 |r|
Show InChI InChI=1S/C34H39N7O/c1-2-24-12-14-26(15-13-24)23-41-32(17-16-25-8-4-3-5-9-25)39-40-33(41)30(38-34(42)31-22-35-18-19-36-31)20-27-21-37-29-11-7-6-10-28(27)29/h3-15,21,30-31,35-37H,2,16-20,22-23H2,1H3,(H,38,42)/t30-,31?/m1/s1
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n/an/a 178n/a 143n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19303
PNG
((2-aminoethyl)[(1R)-1-{4-[(2,4-dimethoxyphenyl)met...)
Show SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NCCN)c(OC)c1 |r|
Show InChI InChI=1S/C31H36N6O2/c1-38-25-14-13-23(29(19-25)39-2)21-37-30(15-12-22-8-4-3-5-9-22)35-36-31(37)28(33-17-16-32)18-24-20-34-27-11-7-6-10-26(24)27/h3-11,13-14,19-20,28,33-34H,12,15-18,21,32H2,1-2H3/t28-/m1/s1
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n/an/a 190n/a 279n/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19342
PNG
(N-[(1R)-2-(1H-indol-3-yl)-1-[5-(2-phenylethyl)-4-(...)
Show SMILES O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1Cc1cccs1)C1CCNCC1 |r|
Show InChI InChI=1S/C31H34N6OS/c38-31(23-14-16-32-17-15-23)34-28(19-24-20-33-27-11-5-4-10-26(24)27)30-36-35-29(13-12-22-7-2-1-3-8-22)37(30)21-25-9-6-18-39-25/h1-11,18,20,23,28,32-33H,12-17,19,21H2,(H,34,38)/t28-/m1/s1
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n/an/a 255n/an/an/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19305
PNG
((2S)-2-amino-N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-...)
Show SMILES CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)N)cc1 |r|
Show InChI InChI=1S/C32H36N6O/c1-3-23-13-15-25(16-14-23)21-38-30(18-17-24-9-5-4-6-10-24)36-37-31(38)29(35-32(39)22(2)33)19-26-20-34-28-12-8-7-11-27(26)28/h4-16,20,22,29,34H,3,17-19,21,33H2,1-2H3,(H,35,39)/t22-,29+/m0/s1
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n/an/a 275n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19316
PNG
((2S)-N-[(1R)-1-[4-(4-ethylphenyl)-5-[2-(1H-indol-3...)
Show SMILES CCc1ccc(cc1)-n1c(CCc2c[nH]c3ccccc23)nnc1[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1 |r|
Show InChI InChI=1S/C35H37N7O/c1-2-23-13-16-26(17-14-23)42-33(18-15-24-21-37-29-10-5-3-8-27(24)29)40-41-34(42)32(39-35(43)31-12-7-19-36-31)20-25-22-38-30-11-6-4-9-28(25)30/h3-6,8-11,13-14,16-17,21-22,31-32,36-38H,2,7,12,15,18-20H2,1H3,(H,39,43)/t31-,32+/m0/s1
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n/an/a 350n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19330
PNG
((2R)-N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phe...)
Show SMILES CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]2CCCCN2)cc1 |r|
Show InChI InChI=1S/C35H40N6O/c1-2-25-15-17-27(18-16-25)24-41-33(20-19-26-10-4-3-5-11-26)39-40-34(41)32(38-35(42)31-14-8-9-21-36-31)22-28-23-37-30-13-7-6-12-29(28)30/h3-7,10-13,15-18,23,31-32,36-37H,2,8-9,14,19-22,24H2,1H3,(H,38,42)/t31-,32-/m1/s1
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n/an/a 375n/an/an/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19336
PNG
(N-[(1R)-2-(1H-indol-3-yl)-1-[4-phenyl-5-(2-phenyle...)
Show SMILES O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1-c1ccccc1)C1CCNCC1 |r|
Show InChI InChI=1S/C32H34N6O/c39-32(24-17-19-33-20-18-24)35-29(21-25-22-34-28-14-8-7-13-27(25)28)31-37-36-30(16-15-23-9-3-1-4-10-23)38(31)26-11-5-2-6-12-26/h1-14,22,24,29,33-34H,15-21H2,(H,35,39)/t29-/m1/s1
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n/an/a 468n/an/an/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19314
PNG
((2S)-N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-phe...)
Show SMILES CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2CCCN2)cc1 |r|
Show InChI InChI=1S/C34H38N6O/c1-2-24-14-16-26(17-15-24)23-40-32(19-18-25-9-4-3-5-10-25)38-39-33(40)31(37-34(41)30-13-8-20-35-30)21-27-22-36-29-12-7-6-11-28(27)29/h3-7,9-12,14-17,22,30-31,35-36H,2,8,13,18-21,23H2,1H3,(H,37,41)/t30-,31+/m0/s1
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n/an/a 490n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19343
PNG
(N-[(1R)-1-[4-(furan-2-ylmethyl)-5-(2-phenylethyl)-...)
Show SMILES O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1Cc1ccco1)C1CCNCC1 |r|
Show InChI InChI=1S/C31H34N6O2/c38-31(23-14-16-32-17-15-23)34-28(19-24-20-33-27-11-5-4-10-26(24)27)30-36-35-29(13-12-22-7-2-1-3-8-22)37(30)21-25-9-6-18-39-25/h1-11,18,20,23,28,32-33H,12-17,19,21H2,(H,34,38)/t28-/m1/s1
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n/an/a 560n/a 183n/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19299
PNG
(2-amino-N-[(1R)-1-{4-[(4-ethylphenyl)methyl]-5-(2-...)
Show SMILES CCc1ccc(Cn2c(CCc3ccccc3)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CN)cc1 |r|
Show InChI InChI=1S/C31H34N6O/c1-2-22-12-14-24(15-13-22)21-37-29(17-16-23-8-4-3-5-9-23)35-36-31(37)28(34-30(38)19-32)18-25-20-33-27-11-7-6-10-26(25)27/h3-15,20,28,33H,2,16-19,21,32H2,1H3,(H,34,38)/t28-/m1/s1
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n/an/a 759n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19315
PNG
((2S)-N-[(1R)-2-(1H-indol-3-yl)-1-[4-phenyl-5-(2-ph...)
Show SMILES O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1-c1ccccc1)[C@@H]1CCCN1 |r|
Show InChI InChI=1S/C31H32N6O/c38-31(27-16-9-19-32-27)34-28(20-23-21-33-26-15-8-7-14-25(23)26)30-36-35-29(18-17-22-10-3-1-4-11-22)37(30)24-12-5-2-6-13-24/h1-8,10-15,21,27-28,32-33H,9,16-20H2,(H,34,38)/t27-,28+/m0/s1
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n/an/a>1.00E+3n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19341
PNG
(N-[(1R)-1-[5-benzyl-4-(pyridin-2-ylmethyl)-4H-1,2,...)
Show SMILES O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(Cc2ccccc2)n1Cc1ccccn1)C1CCNCC1 |r|
Show InChI InChI=1S/C31H33N7O/c39-31(23-13-16-32-17-14-23)35-28(19-24-20-34-27-12-5-4-11-26(24)27)30-37-36-29(18-22-8-2-1-3-9-22)38(30)21-25-10-6-7-15-33-25/h1-12,15,20,23,28,32,34H,13-14,16-19,21H2,(H,35,39)/t28-/m1/s1
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n/an/a>1.00E+3n/an/an/an/an/an/a



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19302
PNG
(2-amino-N-[(1R)-1-[4-(4-ethylphenyl)-5-[2-(1H-indo...)
Show SMILES CCc1ccc(cc1)-n1c(CCc2c[nH]c3ccccc23)nnc1[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CN |r|
Show InChI InChI=1S/C32H33N7O/c1-2-21-11-14-24(15-12-21)39-30(16-13-22-19-34-27-9-5-3-7-25(22)27)37-38-32(39)29(36-31(40)18-33)17-23-20-35-28-10-6-4-8-26(23)28/h3-12,14-15,19-20,29,34-35H,2,13,16-18,33H2,1H3,(H,36,40)/t29-/m1/s1
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n/an/a>1.00E+3n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19320
PNG
(N-[(1R)-2-(1H-indol-3-yl)-1-[5-(2-phenylethyl)-4-(...)
Show SMILES O=C(N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1Cc1ccccn1)C1CCCNC1 |r|
Show InChI InChI=1S/C32H35N7O/c40-32(24-11-8-17-33-20-24)36-29(19-25-21-35-28-14-5-4-13-27(25)28)31-38-37-30(16-15-23-9-2-1-3-10-23)39(31)22-26-12-6-7-18-34-26/h1-7,9-10,12-14,18,21,24,29,33,35H,8,11,15-17,19-20,22H2,(H,36,40)/t24?,29-/m1/s1
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n/an/a>1.00E+3n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19301
PNG
(2-amino-N-[(1R)-1-[4-(2,4-dimethoxyphenyl)-5-(2-ph...)
Show SMILES COc1ccc(c(OC)c1)-n1c(CCc2ccccc2)nnc1[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CN |r,wU:23.38,(4.36,-2.45,;2.85,-2.19,;2.31,-.75,;.8,-.48,;.27,.96,;1.25,2.14,;2.77,1.88,;3.76,3.06,;5.3,3.06,;3.3,.44,;.85,3.63,;2.12,4.51,;3.57,4,;4.74,5.01,;4.74,6.55,;3.4,7.32,;3.4,8.86,;4.74,9.63,;6.07,8.86,;6.07,7.32,;1.67,5.98,;.13,6.02,;-.37,4.56,;-1.71,3.79,;-2.48,2.46,;-2.48,.92,;-1.01,.45,;-1.01,-1.09,;-2.47,-1.57,;-3.1,-2.98,;-4.63,-3.15,;-5.53,-1.9,;-4.91,-.49,;-3.38,-.33,;-3.04,4.56,;-4.38,3.79,;-4.38,2.25,;-5.71,4.56,;-7.04,3.79,)|
Show InChI InChI=1S/C30H32N6O3/c1-38-22-13-14-26(27(17-22)39-2)36-28(15-12-20-8-4-3-5-9-20)34-35-30(36)25(33-29(37)18-31)16-21-19-32-24-11-7-6-10-23(21)24/h3-11,13-14,17,19,25,32H,12,15-16,18,31H2,1-2H3,(H,33,37)/t25-/m1/s1
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n/an/a>1.00E+3n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
Growth hormone secretagogue receptor type 1


(Homo sapiens (Human))		BDBM19300
PNG
(2-amino-N-[(1R)-2-(1H-indol-3-yl)-1-[4-phenyl-5-(2...)
Show SMILES NCC(=O)N[C@H](Cc1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1-c1ccccc1 |r|
Show InChI InChI=1S/C28H28N6O/c29-18-27(35)31-25(17-21-19-30-24-14-8-7-13-23(21)24)28-33-32-26(16-15-20-9-3-1-4-10-20)34(28)22-11-5-2-6-12-22/h1-14,19,25,30H,15-18,29H2,(H,31,35)/t25-/m1/s1
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n/an/a>1.00E+3n/an/an/an/a7.325



CNRS



Assay Description
Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...

J Med Chem 50: 5790-5806 (2007)


Article DOI: 10.1021/jm0704550
BindingDB Entry DOI: 10.7270/Q2HD7SZ4
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%