Affinity Data by PubMed id=18436346

PubMed code 18436346

Found 28 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266158 (CHEMBL510225 \| Dimethyl-[2-(4-naphtho[1,2-d]oxazol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.51E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266161 (2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.71E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266161 (2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.75E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266158 (CHEMBL510225 \| Dimethyl-[2-(4-naphtho[1,2-d]oxazol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.87E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266231 (CHEMBL510460 \| Dimethyl-[3-(4-naphtho[1,2-d]oxazol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.41E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266160 (2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.42E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266159 (CHEMBL506882 \| Diethyl-[2-(4-naphtho[1,2-d]oxazol-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266231 (CHEMBL510460 \| Dimethyl-[3-(4-naphtho[1,2-d]oxazol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.63E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266160 (2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266232 (CHEMBL458009 \| Diethyl-[3-(4-naphtho[1,2-d]oxazol-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.05E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266232 (CHEMBL458009 \| Diethyl-[3-(4-naphtho[1,2-d]oxazol-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266162 (Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266162 (Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.44E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266159 (CHEMBL506882 \| Diethyl-[2-(4-naphtho[1,2-d]oxazol-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.55E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266161 (2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266161 (2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266162 (Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266162 (Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266232 (CHEMBL458009 \| Diethyl-[3-(4-naphtho[1,2-d]oxazol-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266232 (CHEMBL458009 \| Diethyl-[3-(4-naphtho[1,2-d]oxazol-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266231 (CHEMBL510460 \| Dimethyl-[3-(4-naphtho[1,2-d]oxazol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266158 (CHEMBL510225 \| Dimethyl-[2-(4-naphtho[1,2-d]oxazol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266231 (CHEMBL510460 \| Dimethyl-[3-(4-naphtho[1,2-d]oxazol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266158 (CHEMBL510225 \| Dimethyl-[2-(4-naphtho[1,2-d]oxazol...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266159 (CHEMBL506882 \| Diethyl-[2-(4-naphtho[1,2-d]oxazol-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266159 (CHEMBL506882 \| Diethyl-[2-(4-naphtho[1,2-d]oxazol-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266160 (2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50266160 (2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity				Eur J Med Chem 44: 109-16 (2008) Article DOI: 10.1016/j.ejmech.2008.03.009 BindingDB Entry DOI: 10.7270/Q2FN1602
Central Drug Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%