Affinity Data by PubMed id=18507366

PubMed code 18507366

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23174 (6-chloro-1,2-benzoxazol-3-ol \| 6-chlorobenzo[d]iso...) Show SMILES Clc1ccc2c(c1)o[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23175 (6-methyl-1,2-benzoxazol-3-ol \| Benzo[d]isoxazol-3-...) Show SMILES Cc1ccc2c(c1)o[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	269	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23173 (6-fluoro-1,2-benzoxazol-3-ol \| Benzo[d]isoxazol-3-...) Show SMILES Fc1ccc2c(c1)o[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	444	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23170 (5-bromo-1,2-benzoxazol-3-ol \| Benzo[d]isoxazol-3-o...) Show SMILES Brc1ccc2o[nH]c(=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	599	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23178 (6-nitro-1,2-benzoxazol-3-ol \| Benzo[d]isoxazol-3-o...) Show SMILES [O-][N+](=O)c1ccc2c(c1)o[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	722	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23171 (5-iodo-1,2-benzoxazol-3-ol \| Benzo[d]isoxazol-3-ol...) Show SMILES Ic1ccc2o[nH]c(=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23166 (1,2-benzoxazol-3-ol \| benzo[d]isoxazol-3-ol) Show SMILES O=c1[nH]oc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23176 (6-methoxy-1,2-benzoxazol-3-ol \| Benzo[d]isoxazol-3...) Show SMILES COc1ccc2c(c1)o[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23172 (5-nitro-1,2-benzoxazol-3-ol \| Benzo[d]isoxazol-3-o...) Show SMILES [O-][N+](=O)c1ccc2o[nH]c(=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.95E+3	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23179 (6-(trifluoromethyl)-1,2-benzoxazol-3-ol \| Benzo[d]...) Show SMILES FC(F)(F)c1ccc2c(c1)o[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23169 (4-fluoro-1,2-benzoxazol-3-ol \| Benzo[d]isoxazol-3-...) Show SMILES Fc1cccc2o[nH]c(=O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.82E+3	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23181 (7-fluoro-1,2-benzoxazol-3-ol \| Benzo[d]isoxazol-3-...) Show SMILES Fc1cccc2c1o[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23168 (4-(trifluoromethyl)-1,2-benzoxazol-3-ol \| Benzo[d]...) Show SMILES FC(F)(F)c1cccc2o[nH]c(=O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23182 (7-methyl-1,2-benzoxazol-3-ol \| Benzo[d]isoxazol-3-...) Show SMILES Cc1cccc2c1o[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23183 (5-(aminomethyl)-1,2-oxazol-3-ol \| Agarin \| CHEMBL2...) Show SMILES NCc1cc(=O)[nH]o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23180 (7-fluoro-6-(trifluoromethyl)-1,2-benzoxazol-3-ol \|...) Show SMILES Fc1c(ccc2c1o[nH]c2=O)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23186 (6-chloro-3-methoxy-1,2-benzoxazole \| 6-chloro-3-me...) Show SMILES COc1noc2cc(Cl)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23185 (4,5,6,7-tetrahydro-1,2-benzoxazol-3-ol \| 4,5,6,7-t...) Show SMILES O=c1[nH]oc2CCCCc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23177 (6-ethoxy-1,2-benzoxazol-3-ol \| Benzo[d]isoxazol-3-...) Show SMILES CCOc1ccc2c(c1)o[nH]c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair
D-amino-acid oxidase (Sus scrofa (pig))	BDBM23184 ((2S)-2-amino-3-(3-hydroxy-4-methyl-1,2-oxazol-5-yl...) Show SMILES Cc1c(C[C@H](N)C(O)=O)o[nH]c1=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	22
MGI Pharma					Assay Description D-amino acid oxidase (DAAO) was assayed in a 96-well plate format. D-serine was oxidatively deaminated by porcine D-amino acid oxidase in the presenc...				J Med Chem 51: 3357-9 (2008) Article DOI: 10.1021/jm800200u BindingDB Entry DOI: 10.7270/Q21G0JJJ
MGI Pharma					More data for this Ligand-Target Pair

* indicates data uncertainty>20%