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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262085 (CHEMBL468397 | methyl 5-((3-(1H-benzo[d]imidazol-2...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.17 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents at 1 uM by w... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262085 (CHEMBL468397 | methyl 5-((3-(1H-benzo[d]imidazol-2...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.17 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262132 (CHEMBL468409 | methyl 2-(4-bromophenyl)-5-((3-(5,6...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 53.0 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262082 (CHEMBL468217 | ethyl 5-((3-(5,6-dimethyl-1H-benzo[...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50262085 (CHEMBL468397 | methyl 5-((3-(1H-benzo[d]imidazol-2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 178 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Inhibition of human ERG channel | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262083 (CHEMBL468227 | methyl 5-((3-(1H-benzo[d]imidazol-2...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262024 (CHEMBL467174 | ethyl 5-((3-(1H-benzo[d]imidazol-2-...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262131 (CHEMBL468408 | methyl 2-(4-bromophenyl)-2-isopropy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262134 (CHEMBL513836 | ethyl 5-(4-(4-fluorobenzyl)piperazi...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262185 (CHEMBL512604 | methyl 5-(4-(3-(trifluoromethyl)ben...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262241 (CHEMBL468157 | methyl 5-(4-(2,3,4-trimethoxybenzyl...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262133 (CHEMBL467384 | ethyl 5-(4-(4-methoxybenzyl)piperaz...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262242 (2-(4-Bromo-phenyl)-2-isopropyl-5-[4-(3-methyl-benz...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262240 (CHEMBL468156 | methyl 5-(4-(4-methoxybenzyl)pipera...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262182 (CHEMBL511386 | methyl 5-(4-(2-fluorobenzyl)piperaz...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262084 (CHEMBL468228 | methyl 2-isopropyl-5-((3-(5-methoxy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262183 (CHEMBL466767 | methyl 5-(4-(3-fluorobenzyl)piperaz...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262184 (CHEMBL466768 | methyl 5-(4-(4-fluorobenzyl)piperaz...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50117922 ((1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Voltage-dependent T-type calcium channel subunit alpha-1G (Homo sapiens (Human)) | BDBM50262239 (CHEMBL513338 | methyl 2-(4-bromophenyl)-2-isopropy...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 9.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel... | Bioorg Med Chem Lett 18: 4424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.037 BindingDB Entry DOI: 10.7270/Q2TT4QRD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
