Affinity Data by PubMed id=19254846

PubMed code 19254846

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50377988 (CHEMBL552521) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50096598 (((2R,3S,4R,5R)-3-hydroxy-4-(3-methoxybenzamido)-5-...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50096600 (CHEMBL464924 \| N-((2R,3R,4S,5R)-4-Hydroxy-5-hydrox...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50198762 (4-(6,7-diacetoxy-2-oxo-2H-chromen-3-yl)-1,2-phenyl...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50248616 ((8E,11E,14E)-Anacardic acid \| CHEMBL464925) Show SMILES OC(=O)c1c(O)cccc1CCCCCCC\C=C\C\C=C\CC=C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50241244 ((E)-((2R,3S,4S,5R,6S)-6-(5,7-dihydroxy-2-(4-hydrox...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50240591 ((R)-6-(1,1-Dimethyl-allyl)-2-(1-hydroxy-1-methyl-e...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50248617 ((8E,11E)-Anacardic acid \| CHEMBL465536) Show SMILES CCC\C=C\C\C=C\CCCCCCCc1cccc(O)c1C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50249049 (6,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-chrome...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50241529 (7-hydroxy-6-methoxy-3-(4-methoxyphenyl)-4H-chromen...) Show SMILES COc1ccc(cc1)-c1coc2cc(O)c(OC)cc2c1=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50248650 (CHEMBL464507 \| Guajaverin) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM7460 (2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50242207 (CHEMBL455364 \| Mangiferin) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.49E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50241272 ((8E)-Anacardic acid \| 6-(8'E-pentadecaenyl)salicyl...) Show SMILES CCCCCC\C=C\CCCCCCCc1cccc(O)c1C(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.61E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM50174558 (7-hydroxy-2H-1-benzopyran-2-one \| 7-hydroxy-2H-chr...) Show SMILES Oc1ccc2ccc(=O)oc2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal (Trypanosoma cruzi)	BDBM12342 (2H-chromen-2-one \| CHEMBL6466 \| Coumarin) Show SMILES O=c1ccc2ccccc2o1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	6.92E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi recombinant glycosomal GAPDH expressed in Escherichia coli by spectrophotometry				Bioorg Med Chem 17: 2476-82 (2009) Article DOI: 10.1016/j.bmc.2009.01.079 BindingDB Entry DOI: 10.7270/Q2BC40FV
Universidade de S£o Paulo Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%