Affinity Data by PubMed id=19527032

PubMed code 19527032

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human))	BDBM50293841 (3-((3,5-dimethylisoxazol-4-yl)methoxy)-N-(4-methyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISA				J Med Chem 52: 4087-90 (2009) Article DOI: 10.1021/jm8015987 BindingDB Entry DOI: 10.7270/Q23T9H81
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human))	BDBM50293840 (CHEMBL562095 \| N-(4-methoxy-3-(piperidin-1-ylsulfo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISA				J Med Chem 52: 4087-90 (2009) Article DOI: 10.1021/jm8015987 BindingDB Entry DOI: 10.7270/Q23T9H81
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human))	BDBM50293842 (1-(4-morpholinophenylamino)-1-oxopropan-2-yl 1-hyd...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISA				J Med Chem 52: 4087-90 (2009) Article DOI: 10.1021/jm8015987 BindingDB Entry DOI: 10.7270/Q23T9H81
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human))	BDBM50293843 (1,8-diamino-6-methoxy-3-(4-(2-methoxyphenyl)pipera...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISA				J Med Chem 52: 4087-90 (2009) Article DOI: 10.1021/jm8015987 BindingDB Entry DOI: 10.7270/Q23T9H81
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Ras-related C3 botulinum toxin substrate 1 (Homo sapiens (Human))	BDBM50293839 (2-(4-fluoro-3-nitrophenylamino)-N-(4-morpholinophe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Inhibition of PDGF-BB-stimulated Rac1 activity in human aortic smooth muscle cells assessed as reduction of Rac1GTP level after 4 hrs by G-LISA				J Med Chem 52: 4087-90 (2009) Article DOI: 10.1021/jm8015987 BindingDB Entry DOI: 10.7270/Q23T9H81
Universit£ degli Studi di Milano Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%