Affinity Data by PubMed id=21419531

PubMed code 21419531

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50241727 ((S)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic ac...) Show SMILES Cn1cc(C[C@H](N)C(O)=O)c2ccccc12 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Competitive inhibition of histidine-tagged human recombinant IDO expressed in bacterial strain BL21 AI using L-Trptophan as substrate measured at 490...				Eur J Med Chem 46: 3058-65 (2011) Article DOI: 10.1016/j.ejmech.2011.02.049 BindingDB Entry DOI: 10.7270/Q2F19029
University of Namur Curated by ChEMBL					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50336434 (1-(1H-Indol-2-yl)-2-pyridin-3-yl-ethanone \| CHEMBL...) Show SMILES O=C(Cc1cccnc1)c1cc2ccccc2[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Uncompetitive inhibition of histidine-tagged human recombinant IDO expressed in bacterial strain BL21 AI using L-Trptophan as substrate measured at 4...				Eur J Med Chem 46: 3058-65 (2011) Article DOI: 10.1016/j.ejmech.2011.02.049 BindingDB Entry DOI: 10.7270/Q2F19029
University of Namur Curated by ChEMBL					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM50347507 (CHEMBL1802300) Show SMILES Cn1c(cc2cc(F)ccc12)C(=O)Cc1cccnc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Namur Curated by ChEMBL					Assay Description Competitive inhibition of histidine-tagged human recombinant IDO expressed in bacterial strain BL21 AI using L-Trptophan as substrate measured at 490...				Eur J Med Chem 46: 3058-65 (2011) Article DOI: 10.1016/j.ejmech.2011.02.049 BindingDB Entry DOI: 10.7270/Q2F19029
University of Namur Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%