Found 46 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360680
(CHEMBL1933918)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)N[C@@H](C)c1ccccc1 |r| Show InChI InChI=1S/C27H28N2O6/c1-4-25(30)29-20-11-13-22(35-24-14-18(15-26(31)32)10-12-23(24)34-3)21(16-20)27(33)28-17(2)19-8-6-5-7-9-19/h5-14,16-17H,4,15H2,1-3H3,(H,28,33)(H,29,30)(H,31,32)/t17-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360682
(CHEMBL1933920)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)NC(C)(C)Cc1ccc(F)cc1 Show InChI InChI=1S/C29H31FN2O6/c1-5-26(33)31-21-11-13-23(38-25-14-19(15-27(34)35)8-12-24(25)37-4)22(16-21)28(36)32-29(2,3)17-18-6-9-20(30)10-7-18/h6-14,16H,5,15,17H2,1-4H3,(H,31,33)(H,32,36)(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50302824
(2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylca...)Show SMILES CCNC(=O)c1ccc(Oc2c(OC)cc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C25H24Cl2N2O8S/c1-4-28-25(32)15-5-7-19(18(12-15)29-38(33,34)22-8-6-16(26)13-17(22)27)37-24-20(35-2)9-14(11-23(30)31)10-21(24)36-3/h5-10,12-13,29H,4,11H2,1-3H3,(H,28,32)(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360679
(CHEMBL1933917)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)N[C@@H](C)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C27H27ClN2O6/c1-4-25(31)30-20-10-12-22(36-24-13-17(14-26(32)33)5-11-23(24)35-3)21(15-20)27(34)29-16(2)18-6-8-19(28)9-7-18/h5-13,15-16H,4,14H2,1-3H3,(H,29,34)(H,30,31)(H,32,33)/t16-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360681
(CHEMBL1933919)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)NCCc1ccc(F)cc1 Show InChI InChI=1S/C27H27FN2O6/c1-3-25(31)30-20-9-11-22(36-24-14-18(15-26(32)33)6-10-23(24)35-2)21(16-20)27(34)29-13-12-17-4-7-19(28)8-5-17/h4-11,14,16H,3,12-13,15H2,1-2H3,(H,29,34)(H,30,31)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50302828
(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C26H26Cl2N2O7S/c1-3-4-11-29-26(33)17-6-9-21(37-22-8-5-16(13-25(31)32)12-23(22)36-2)20(14-17)30-38(34,35)24-10-7-18(27)15-19(24)28/h5-10,12,14-15,30H,3-4,11,13H2,1-2H3,(H,29,33)(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360668
(CHEMBL1933763)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(cc2OC)C(F)(F)C(O)=O)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C26H24Cl2F2N2O7S/c1-3-4-11-31-24(33)15-5-8-20(19(12-15)32-40(36,37)23-10-7-17(27)14-18(23)28)39-21-9-6-16(13-22(21)38-2)26(29,30)25(34)35/h5-10,12-14,32H,3-4,11H2,1-2H3,(H,31,33)(H,34,35) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360671
(CHEMBL1933766)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C26H27ClN2O7S/c1-3-4-13-28-26(32)18-6-12-22(36-23-11-5-17(15-25(30)31)14-24(23)35-2)21(16-18)29-37(33,34)20-9-7-19(27)8-10-20/h5-12,14,16,29H,3-4,13,15H2,1-2H3,(H,28,32)(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360675
(CHEMBL1933913)Show SMILES COc1cc(CC(O)=O)ccc1Oc1ccc(cc1CS(=O)(=O)c1ccc(Cl)cc1Cl)C(=O)NC1CCC1 Show InChI InChI=1S/C27H25Cl2NO7S/c1-36-24-11-16(12-26(31)32)5-8-23(24)37-22-9-6-17(27(33)30-20-3-2-4-20)13-18(22)15-38(34,35)25-10-7-19(28)14-21(25)29/h5-11,13-14,20H,2-4,12,15H2,1H3,(H,30,33)(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360680
(CHEMBL1933918)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)N[C@@H](C)c1ccccc1 |r| Show InChI InChI=1S/C27H28N2O6/c1-4-25(30)29-20-11-13-22(35-24-14-18(15-26(31)32)10-12-23(24)34-3)21(16-20)27(33)28-17(2)19-8-6-5-7-9-19/h5-14,16-17H,4,15H2,1-3H3,(H,28,33)(H,29,30)(H,31,32)/t17-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasma |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360670
(CHEMBL1933765)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)NS(C)(=O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C27H29Cl2N3O8S2/c1-4-5-12-30-27(34)18-7-10-22(21(15-18)31-42(37,38)25-11-8-19(28)16-20(25)29)40-23-9-6-17(13-24(23)39-2)14-26(33)32-41(3,35)36/h6-11,13,15-16,31H,4-5,12,14H2,1-3H3,(H,30,34)(H,32,33) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360669
(CHEMBL1933764)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(Cc3nnn[nH]3)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C26H26Cl2N6O5S/c1-3-4-11-29-26(35)17-6-9-21(20(14-17)32-40(36,37)24-10-7-18(27)15-19(24)28)39-22-8-5-16(12-23(22)38-2)13-25-30-33-34-31-25/h5-10,12,14-15,32H,3-4,11,13H2,1-2H3,(H,29,35)(H,30,31,33,34) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360677
(CHEMBL1933915)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C26H25ClN2O6/c1-3-24(30)29-19-9-11-21(35-23-12-17(13-25(31)32)6-10-22(23)34-2)20(14-19)26(33)28-15-16-4-7-18(27)8-5-16/h4-12,14H,3,13,15H2,1-2H3,(H,28,33)(H,29,30)(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50302828
(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C26H26Cl2N2O7S/c1-3-4-11-29-26(33)17-6-9-21(37-22-8-5-16(13-25(31)32)12-23(22)36-2)20(14-17)30-38(34,35)24-10-7-18(27)15-19(24)28/h5-10,12,14-15,30H,3-4,11,13H2,1-2H3,(H,29,33)(H,31,32) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360667
(CHEMBL1933762)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(cc2OC)C2(CCCC2)C(O)=O)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C30H32Cl2N2O7S/c1-3-4-15-33-28(35)19-7-10-24(23(16-19)34-42(38,39)27-12-9-21(31)18-22(27)32)41-25-11-8-20(17-26(25)40-2)30(29(36)37)13-5-6-14-30/h7-12,16-18,34H,3-6,13-15H2,1-2H3,(H,33,35)(H,36,37) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360671
(CHEMBL1933766)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C26H27ClN2O7S/c1-3-4-13-28-26(32)18-6-12-22(36-23-11-5-17(15-25(30)31)14-24(23)35-2)21(16-18)29-37(33,34)20-9-7-19(27)8-10-20/h5-12,14,16,29H,3-4,13,15H2,1-2H3,(H,28,32)(H,30,31) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360681
(CHEMBL1933919)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)NCCc1ccc(F)cc1 Show InChI InChI=1S/C27H27FN2O6/c1-3-25(31)30-20-9-11-22(36-24-14-18(15-26(32)33)6-10-23(24)35-2)21(16-20)27(34)29-13-12-17-4-7-19(28)8-5-17/h4-11,14,16H,3,12-13,15H2,1-2H3,(H,29,34)(H,30,31)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasma |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360678
(CHEMBL1933916)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)N[C@H](C)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C27H27ClN2O6/c1-4-25(31)30-20-10-12-22(36-24-13-17(14-26(32)33)5-11-23(24)35-3)21(15-20)27(34)29-16(2)18-6-8-19(28)9-7-18/h5-13,15-16H,4,14H2,1-3H3,(H,29,34)(H,30,31)(H,32,33)/t16-/m1/s1 | PDB
Reactome pathway
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UniProtKB/SwissProt
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antibodypedia
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360682
(CHEMBL1933920)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)NC(C)(C)Cc1ccc(F)cc1 Show InChI InChI=1S/C29H31FN2O6/c1-5-26(33)31-21-11-13-23(38-25-14-19(15-27(34)35)8-12-24(25)37-4)22(16-21)28(36)32-29(2,3)17-18-6-9-20(30)10-7-18/h6-14,16H,5,15,17H2,1-4H3,(H,31,33)(H,32,36)(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasma |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360679
(CHEMBL1933917)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)N[C@@H](C)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C27H27ClN2O6/c1-4-25(31)30-20-10-12-22(36-24-13-17(14-26(32)33)5-11-23(24)35-3)21(15-20)27(34)29-16(2)18-6-8-19(28)9-7-18/h5-13,15-16H,4,14H2,1-3H3,(H,29,34)(H,30,31)(H,32,33)/t16-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasma |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50302817
(2-(3-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylca...)Show SMILES CCNC(=O)c1ccc(Oc2cccc(CC(O)=O)c2)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C23H20Cl2N2O6S/c1-2-26-23(30)15-6-8-20(33-17-5-3-4-14(10-17)11-22(28)29)19(12-15)27-34(31,32)21-9-7-16(24)13-18(21)25/h3-10,12-13,27H,2,11H2,1H3,(H,26,30)(H,28,29) | PDB
Reactome pathway
KEGG
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antibodypedia
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50302824
(2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylca...)Show SMILES CCNC(=O)c1ccc(Oc2c(OC)cc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C25H24Cl2N2O8S/c1-4-28-25(32)15-5-7-19(18(12-15)29-38(33,34)22-8-6-16(26)13-17(22)27)37-24-20(35-2)9-14(11-23(30)31)10-21(24)36-3/h5-10,12-13,29H,4,11H2,1-3H3,(H,28,32)(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasma |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50302828
(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C26H26Cl2N2O7S/c1-3-4-11-29-26(33)17-6-9-21(37-22-8-5-16(13-25(31)32)12-23(22)36-2)20(14-17)30-38(34,35)24-10-7-18(27)15-19(24)28/h5-10,12,14-15,30H,3-4,11,13H2,1-2H3,(H,29,33)(H,31,32) | PDB
Reactome pathway
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CHEMBL
MCE
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasma |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360677
(CHEMBL1933915)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C26H25ClN2O6/c1-3-24(30)29-19-9-11-21(35-23-12-17(13-25(31)32)6-10-22(23)34-2)20(14-19)26(33)28-15-16-4-7-18(27)8-5-16/h4-12,14H,3,13,15H2,1-2H3,(H,28,33)(H,29,30)(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasma |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360676
(CHEMBL1933914)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(c1)S(=O)(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C26H27ClN2O7S/c1-3-4-13-28-26(32)18-6-12-22(36-21-11-5-17(15-25(30)31)14-23(21)35-2)24(16-18)37(33,34)29-20-9-7-19(27)8-10-20/h5-12,14,16,29H,3-4,13,15H2,1-2H3,(H,28,32)(H,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360673
(CHEMBL1933768)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NCCc2ccccc2)c1 Show InChI InChI=1S/C28H32N2O5/c1-3-4-15-30-28(33)22-11-13-24(23(19-22)29-16-14-20-8-6-5-7-9-20)35-25-12-10-21(18-27(31)32)17-26(25)34-2/h5-13,17,19,29H,3-4,14-16,18H2,1-2H3,(H,30,33)(H,31,32) | PDB
Reactome pathway
KEGG
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antibodypedia
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360674
(CHEMBL1933769)Show SMILES CCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NC(=O)NCc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C26H26ClN3O6/c1-3-28-25(33)18-7-11-21(36-22-10-6-17(13-24(31)32)12-23(22)35-2)20(14-18)30-26(34)29-15-16-4-8-19(27)9-5-16/h4-12,14H,3,13,15H2,1-2H3,(H,28,33)(H,31,32)(H2,29,30,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360668
(CHEMBL1933763)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(cc2OC)C(F)(F)C(O)=O)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C26H24Cl2F2N2O7S/c1-3-4-11-31-24(33)15-5-8-20(19(12-15)32-40(36,37)23-10-7-17(27)14-18(23)28)39-21-9-6-16(13-22(21)38-2)26(29,30)25(34)35/h5-10,12-14,32H,3-4,11H2,1-2H3,(H,31,33)(H,34,35) | UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasma |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360672
(CHEMBL1933767)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NCc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C27H29ClN2O5/c1-3-4-13-29-27(33)20-8-12-23(22(16-20)30-17-18-5-9-21(28)10-6-18)35-24-11-7-19(15-26(31)32)14-25(24)34-2/h5-12,14,16,30H,3-4,13,15,17H2,1-2H3,(H,29,33)(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360678
(CHEMBL1933916)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)N[C@H](C)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C27H27ClN2O6/c1-4-25(31)30-20-10-12-22(36-24-13-17(14-26(32)33)5-11-23(24)35-3)21(15-20)27(34)29-16(2)18-6-8-19(28)9-7-18/h5-13,15-16H,4,14H2,1-3H3,(H,29,34)(H,30,31)(H,32,33)/t16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTh2 receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasma |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50302828
(2-(4-(4-(butylcarbamoyl)-2-(2,4-dichlorophenylsulf...)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C26H26Cl2N2O7S/c1-3-4-11-29-26(33)17-6-9-21(37-22-8-5-16(13-25(31)32)12-23(22)36-2)20(14-17)30-38(34,35)24-10-7-18(27)15-19(24)28/h5-10,12,14-15,30H,3-4,11,13H2,1-2H3,(H,29,33)(H,31,32) | UniProtKB/SwissProt
antibodypedia
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| Purchase
CHEMBL
MCE
PC cid
PC sid
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Patents
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| Article
PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasma |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360670
(CHEMBL1933765)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)NS(C)(=O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C27H29Cl2N3O8S2/c1-4-5-12-30-27(34)18-7-10-22(21(15-18)31-42(37,38)25-11-8-19(28)16-20(25)29)40-23-9-6-17(13-24(23)39-2)14-26(33)32-41(3,35)36/h6-11,13,15-16,31H,4-5,12,14H2,1-3H3,(H,30,34)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360669
(CHEMBL1933764)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(Cc3nnn[nH]3)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C26H26Cl2N6O5S/c1-3-4-11-29-26(35)17-6-9-21(20(14-17)32-40(36,37)24-10-7-18(27)15-19(24)28)39-22-8-5-16(12-23(22)38-2)13-25-30-33-34-31-25/h5-10,12,14-15,32H,3-4,11,13H2,1-2H3,(H,29,35)(H,30,31,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360668
(CHEMBL1933763)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(cc2OC)C(F)(F)C(O)=O)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C26H24Cl2F2N2O7S/c1-3-4-11-31-24(33)15-5-8-20(19(12-15)32-40(36,37)23-10-7-17(27)14-18(23)28)39-21-9-6-16(13-22(21)38-2)26(29,30)25(34)35/h5-10,12-14,32H,3-4,11H2,1-2H3,(H,31,33)(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360667
(CHEMBL1933762)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(cc2OC)C2(CCCC2)C(O)=O)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C30H32Cl2N2O7S/c1-3-4-15-33-28(35)19-7-10-24(23(16-19)34-42(38,39)27-12-9-21(31)18-22(27)32)41-25-11-8-20(17-26(25)40-2)30(29(36)37)13-5-6-14-30/h7-12,16-18,34H,3-6,13-15H2,1-2H3,(H,33,35)(H,36,37) | UniProtKB/SwissProt
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| CHEMBL
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UniChem
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| Article
PubMed
| n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 50 % human plasma |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360675
(CHEMBL1933913)Show SMILES COc1cc(CC(O)=O)ccc1Oc1ccc(cc1CS(=O)(=O)c1ccc(Cl)cc1Cl)C(=O)NC1CCC1 Show InChI InChI=1S/C27H25Cl2NO7S/c1-36-24-11-16(12-26(31)32)5-8-23(24)37-22-9-6-17(27(33)30-20-3-2-4-20)13-18(22)15-38(34,35)25-10-7-19(28)14-21(25)29/h5-11,13-14,20H,2-4,12,15H2,1H3,(H,30,33)(H,31,32) | UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360666
(CHEMBL1933761)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(cc2OC)C2(CC2)C(O)=O)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C28H28Cl2N2O7S/c1-3-4-13-31-26(33)17-5-8-22(21(14-17)32-40(36,37)25-10-7-19(29)16-20(25)30)39-23-9-6-18(15-24(23)38-2)28(11-12-28)27(34)35/h5-10,14-16,32H,3-4,11-13H2,1-2H3,(H,31,33)(H,34,35) | UniProtKB/SwissProt
antibodypedia
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50302817
(2-(3-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylca...)Show SMILES CCNC(=O)c1ccc(Oc2cccc(CC(O)=O)c2)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C23H20Cl2N2O6S/c1-2-26-23(30)15-6-8-20(33-17-5-3-4-14(10-17)11-22(28)29)19(12-15)27-34(31,32)21-9-7-16(24)13-18(21)25/h3-10,12-13,27H,2,11H2,1H3,(H,26,30)(H,28,29) | UniProtKB/SwissProt
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UniChem
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PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360667
(CHEMBL1933762)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(cc2OC)C2(CCCC2)C(O)=O)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C30H32Cl2N2O7S/c1-3-4-15-33-28(35)19-7-10-24(23(16-19)34-42(38,39)27-12-9-21(31)18-22(27)32)41-25-11-8-20(17-26(25)40-2)30(29(36)37)13-5-6-14-30/h7-12,16-18,34H,3-6,13-15H2,1-2H3,(H,33,35)(H,36,37) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor 2
(Homo sapiens (Human)) | BDBM50360666
(CHEMBL1933761)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(cc2OC)C2(CC2)C(O)=O)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C28H28Cl2N2O7S/c1-3-4-13-31-26(33)17-5-8-22(21(14-17)32-40(36,37)25-10-7-19(29)16-20(25)30)39-23-9-6-18(15-24(23)38-2)28(11-12-28)27(34)35/h5-10,14-16,32H,3-4,11-13H2,1-2H3,(H,31,33)(H,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human CRTH2 receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360680
(CHEMBL1933918)Show SMILES CCC(=O)Nc1ccc(Oc2cc(CC(O)=O)ccc2OC)c(c1)C(=O)N[C@@H](C)c1ccccc1 |r| Show InChI InChI=1S/C27H28N2O6/c1-4-25(30)29-20-11-13-22(35-24-14-18(15-26(31)32)10-12-23(24)34-3)21(16-20)27(33)28-17(2)19-8-6-5-7-9-19/h5-14,16-17H,4,15H2,1-3H3,(H,28,33)(H,29,30)(H,31,32)/t17-/m0/s1 | UniProtKB/SwissProt
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UniChem
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PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360676
(CHEMBL1933914)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(c1)S(=O)(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C26H27ClN2O7S/c1-3-4-13-28-26(32)18-6-12-22(36-21-11-5-17(15-25(30)31)14-23(21)35-2)24(16-18)37(33,34)29-20-9-7-19(27)8-10-20/h5-12,14,16,29H,3-4,13,15H2,1-2H3,(H,28,32)(H,30,31) | UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360672
(CHEMBL1933767)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NCc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C27H29ClN2O5/c1-3-4-13-29-27(33)20-8-12-23(22(16-20)30-17-18-5-9-21(28)10-6-18)35-24-11-7-19(15-26(31)32)14-25(24)34-2/h5-12,14,16,30H,3-4,13,15,17H2,1-2H3,(H,29,33)(H,31,32) | UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360674
(CHEMBL1933769)Show SMILES CCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NC(=O)NCc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C26H26ClN3O6/c1-3-28-25(33)18-7-11-21(36-22-10-6-17(13-24(31)32)12-23(22)35-2)20(14-18)30-26(34)29-15-16-4-8-19(27)9-5-16/h4-12,14H,3,13,15H2,1-2H3,(H,28,33)(H,31,32)(H2,29,30,34) | UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50360673
(CHEMBL1933768)Show SMILES CCCCNC(=O)c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NCCc2ccccc2)c1 Show InChI InChI=1S/C28H32N2O5/c1-3-4-15-30-28(33)22-11-13-24(23(19-22)29-16-14-20-8-6-5-7-9-20)35-25-12-10-21(18-27(31)32)17-26(25)34-2/h5-13,17,19,29H,3-4,14-16,18H2,1-2H3,(H,30,33)(H,31,32) | UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
Prostaglandin D2 receptor
(Homo sapiens (Human)) | BDBM50302824
(2-(4-(2-(2,4-dichlorophenylsulfonamido)-4-(ethylca...)Show SMILES CCNC(=O)c1ccc(Oc2c(OC)cc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C25H24Cl2N2O8S/c1-4-28-25(32)15-5-7-19(18(12-15)29-38(33,34)22-8-6-16(26)13-17(22)27)37-24-20(35-2)9-14(11-23(30)31)10-21(24)36-3/h5-10,12-13,29H,4,11H2,1-3H3,(H,28,32)(H,30,31) | UniProtKB/SwissProt
antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGD2 from human DP receptor expressed in 293 cells by scintillation counting in presence of 0.5 % BSA |
Bioorg Med Chem Lett 22: 367-70 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.123
BindingDB Entry DOI: 10.7270/Q2057GB8 |
More data for this
Ligand-Target Pair | |
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