Found 122 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.0398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of radioligand from human 5HT4R by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of radioligand from human 5HT4R by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399621
(CHEMBL2181166)Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of radioligand from human 5HT4R by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of radioligand from human 5HT4R by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of radioligand from human 5HT4R by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399621
(CHEMBL2181166)Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 13.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 13.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 20.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399633
(CHEMBL2181190)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-21-18(7-5-8-19(21)23)17-6-3-4-9-20(17)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 21.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 21.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399617
(CHEMBL2181172)Show InChI InChI=1S/C21H25N3O/c1-2-11-24-12-8-16(9-13-24)15-25-21-18-7-10-22-14-19(18)17-5-3-4-6-20(17)23-21/h3-7,10,14,16H,2,8-9,11-13,15H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 22.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 29.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399618
(CHEMBL2181185)Show InChI InChI=1S/C22H25FN2O/c1-2-11-25-12-9-16(10-13-25)15-26-22-20-6-4-3-5-18(20)19-8-7-17(23)14-21(19)24-22/h3-8,14,16H,2,9-13,15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 40.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399632
(CHEMBL2177145)Show InChI InChI=1S/C22H26N2O/c1-2-13-24-14-11-17(12-15-24)16-25-22-20-9-4-3-7-18(20)19-8-5-6-10-21(19)23-22/h3-10,17H,2,11-16H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 51.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399631
(CHEMBL2181186)Show InChI InChI=1S/C23H28N2O/c1-3-13-25-14-11-18(12-15-25)16-26-23-21-9-5-4-8-19(21)20-10-6-7-17(2)22(20)24-23/h4-10,18H,3,11-16H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399618
(CHEMBL2181185)Show InChI InChI=1S/C22H25FN2O/c1-2-11-25-12-9-16(10-13-25)15-26-22-20-6-4-3-5-18(20)19-8-7-17(23)14-21(19)24-22/h3-8,14,16H,2,9-13,15H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 101 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399630
(CHEMBL2181167)Show SMILES Ic1ccc(CCCN2CCC(COc3nc4ccccc4c4ccccc34)CC2)cc1 Show InChI InChI=1S/C28H29IN2O/c29-23-13-11-21(12-14-23)6-5-17-31-18-15-22(16-19-31)20-32-28-26-9-2-1-7-24(26)25-8-3-4-10-27(25)30-28/h1-4,7-14,22H,5-6,15-20H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 136 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50399621
(CHEMBL2181166)Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT7 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 153 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT7 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399629
(CHEMBL2181175)Show InChI InChI=1S/C22H25FN2O/c1-2-11-25-12-9-16(10-13-25)15-26-22-20-14-17(23)7-8-18(20)19-5-3-4-6-21(19)24-22/h3-8,14,16H,2,9-13,15H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 154 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 162 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399628
(CHEMBL2181173)Show InChI InChI=1S/C22H25FN2O/c1-2-11-25-12-9-16(10-13-25)15-26-22-19-8-7-17(23)14-20(19)18-5-3-4-6-21(18)24-22/h3-8,14,16H,2,9-13,15H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 209 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399627
(CHEMBL2181181)Show InChI InChI=1S/C23H28N2O2/c1-3-12-25-13-10-17(11-14-25)16-27-23-20-7-5-4-6-19(20)21-15-18(26-2)8-9-22(21)24-23/h4-9,15,17H,3,10-14,16H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 233 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399626
(CHEMBL2181180)Show InChI InChI=1S/C23H28N2O/c1-3-12-25-13-10-18(11-14-25)16-26-23-20-7-5-4-6-19(20)21-15-17(2)8-9-22(21)24-23/h4-9,15,18H,3,10-14,16H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 246 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50399621
(CHEMBL2181166)Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 341 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2C by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 384 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT7 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50399621
(CHEMBL2181166)Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2C by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399617
(CHEMBL2181172)Show InChI InChI=1S/C21H25N3O/c1-2-11-24-12-8-16(9-13-24)15-25-21-18-7-10-22-14-19(18)17-5-3-4-6-20(17)23-21/h3-7,10,14,16H,2,8-9,11-13,15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 403 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from human recombinant 5HT4R expressed in HEK293T cells |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50399621
(CHEMBL2181166)Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT3 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 492 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2C by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 627 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 641 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT3 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT3 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50399621
(CHEMBL2181166)Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 680 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399625
(CHEMBL2181184)Show InChI InChI=1S/C23H28N2O/c1-3-12-25-13-10-18(11-14-25)16-26-23-21-7-5-4-6-19(21)20-9-8-17(2)15-22(20)24-23/h4-9,15,18H,3,10-14,16H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 691 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT3 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 729 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2C by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 772 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2C by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50399621
(CHEMBL2181166)Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 810 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT7 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2C by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT3 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 5A
(Homo sapiens (Human)) | BDBM50399621
(CHEMBL2181166)Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT5A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(GUINEA PIG) | BDBM50399624
(CHEMBL2181183)Show InChI InChI=1S/C23H28N2O2/c1-3-12-25-13-10-17(11-14-25)16-27-23-21-7-5-4-6-19(21)20-9-8-18(26-2)15-22(20)24-23/h4-9,15,17H,3,10-14,16H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Displacement of [3H]GR113808 from 5HT4R in guinea pig striatal membranes |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT7 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT7 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1D by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT3 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1D by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2C by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT7 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 5A
(Homo sapiens (Human)) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT5A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT6 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT6 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 5A
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT5A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1E
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1E by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1D by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 5A
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT5A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1E
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1E by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1E
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1E by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT7 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1D by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1D by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT6 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT6 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 5A
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT5A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT3 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1E
(Homo sapiens (Human)) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1E by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1E
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1E by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50399621
(CHEMBL2181166)Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50399623
(CHEMBL2181169)Show InChI InChI=1S/C22H25IN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 5A
(Homo sapiens (Human)) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT5A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 5A
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT5A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT3 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1E
(Homo sapiens (Human)) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1E by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1E
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1E by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT6 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT6 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 5A
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT5A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1D by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50399622
(CHEMBL2181168)Show InChI InChI=1S/C21H24IN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1B by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50399621
(CHEMBL2181166)Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT6 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT6 by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2C by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50399614
(CHEMBL2181170)Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2A by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50399621
(CHEMBL2181166)Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1D by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT1D by Cerep protocol based assay |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399619
(CHEMBL2181189)Show InChI InChI=1S/C22H25FN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 63.1 | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human recombinant 5HT4R expressed in HEK293T cells assessed as Gs activation |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399615
(CHEMBL2181171)Show InChI InChI=1S/C21H25N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-8,11,16H,2,9-10,12-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human recombinant 5HT4R expressed in HEK293T cells assessed as Gs activation |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399620
(CHEMBL2181187)Show InChI InChI=1S/C23H28N2O2/c1-3-13-25-14-11-17(12-15-25)16-27-23-20-8-5-4-7-18(20)19-9-6-10-21(26-2)22(19)24-23/h4-10,17H,3,11-16H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 79.4 | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human recombinant 5HT4R expressed in HEK293T cells assessed as Gs activation |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50399616
(CHEMBL2181188)Show InChI InChI=1S/C22H25ClN2O/c1-2-12-25-13-10-16(11-14-25)15-26-22-19-7-4-3-6-17(19)18-8-5-9-20(23)21(18)24-22/h3-9,16H,2,10-15H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 251 | n/a | n/a | n/a | n/a |
Universit£ de Caen Basse-Normandie
Curated by ChEMBL
| Assay Description
Inverse agonist activity at human recombinant 5HT4R expressed in HEK293T cells assessed as Gs activation |
J Med Chem 55: 9693-707 (2012)
Article DOI: 10.1021/jm300943r
BindingDB Entry DOI: 10.7270/Q2ZC8417 |
More data for this
Ligand-Target Pair | |
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