Found 66 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445521
(CHEMBL3103033 | US11345702, Table 1.21 | US2023039...)Show InChI InChI=1S/C19H18ClN3O/c20-15-5-4-6-16(12-15)23-13-21-17-11-14(7-8-18(17)23)19(24)22-9-2-1-3-10-22/h4-8,11-13H,1-3,9-10H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM30884
(1-(3-methylphenyl)-5-(piperidin-1-ylcarbonyl)-1H-b...)Show InChI InChI=1S/C20H21N3O/c1-15-6-5-7-17(12-15)23-14-21-18-13-16(8-9-19(18)23)20(24)22-10-3-2-4-11-22/h5-9,12-14H,2-4,10-11H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445520
(CHEMBL3103034)Show InChI InChI=1S/C20H21N3O2/c1-25-17-7-5-6-16(13-17)23-14-21-18-12-15(8-9-19(18)23)20(24)22-10-3-2-4-11-22/h5-9,12-14H,2-4,10-11H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445514
(CHEMBL3103040 | US11345702, Table 1.33 | US2023039...)Show InChI InChI=1S/C20H21N3O2/c1-25-17-8-6-16(7-9-17)23-14-21-18-13-15(5-10-19(18)23)20(24)22-11-3-2-4-12-22/h5-10,13-14H,2-4,11-12H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445516
(CHEMBL3103038)Show InChI InChI=1S/C20H21N3O/c1-15-5-8-17(9-6-15)23-14-21-18-13-16(7-10-19(18)23)20(24)22-11-3-2-4-12-22/h5-10,13-14H,2-4,11-12H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445537
(CHEMBL3103018)Show SMILES CC1CCCN(C1)C(=O)c1ccc2n(cnc2c1)-c1cccc(C)c1 Show InChI InChI=1S/C21H23N3O/c1-15-5-3-7-18(11-15)24-14-22-19-12-17(8-9-20(19)24)21(25)23-10-4-6-16(2)13-23/h3,5,7-9,11-12,14,16H,4,6,10,13H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445562
(CHEMBL3102994)Show SMILES Cc1cc(c(C)n1-c1ccc(Cl)c(Cl)c1)-c1nnc2CCCCCn12 Show InChI InChI=1S/C19H20Cl2N4/c1-12-10-15(19-23-22-18-6-4-3-5-9-24(18)19)13(2)25(12)14-7-8-16(20)17(21)11-14/h7-8,10-11H,3-6,9H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445523
(CHEMBL3103032)Show InChI InChI=1S/C19H19N3O/c23-19(21-11-5-2-6-12-21)15-9-10-18-17(13-15)20-14-22(18)16-7-3-1-4-8-16/h1,3-4,7-10,13-14H,2,5-6,11-12H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445515
(CHEMBL3103039)Show InChI InChI=1S/C19H18ClN3O/c20-15-5-7-16(8-6-15)23-13-21-17-12-14(4-9-18(17)23)19(24)22-10-2-1-3-11-22/h4-9,12-13H,1-3,10-11H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445522
(CHEMBL3102860)Show InChI InChI=1S/C20H21N3O2/c1-25-19-8-4-3-7-18(19)23-14-21-16-13-15(9-10-17(16)23)20(24)22-11-5-2-6-12-22/h3-4,7-10,13-14H,2,5-6,11-12H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445561
(CHEMBL3102995)Show InChI InChI=1S/C19H21ClN4/c1-13-11-17(14(2)24(13)16-8-6-7-15(20)12-16)19-22-21-18-9-4-3-5-10-23(18)19/h6-8,11-12H,3-5,9-10H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445511
(CHEMBL3103043)Show InChI InChI=1S/C17H23N3O/c1-17(2,3)20-12-18-14-11-13(7-8-15(14)20)16(21)19-9-5-4-6-10-19/h7-8,11-12H,4-6,9-10H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445555
(CHEMBL3103000)Show InChI InChI=1S/C20H24N4/c1-14-8-10-17(11-9-14)24-15(2)13-18(16(24)3)20-22-21-19-7-5-4-6-12-23(19)20/h8-11,13H,4-7,12H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445560
(CHEMBL3102996)Show InChI InChI=1S/C19H21ClN4/c1-13-12-17(14(2)24(13)16-9-7-15(20)8-10-16)19-22-21-18-6-4-3-5-11-23(18)19/h7-10,12H,3-6,11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445549
(CHEMBL3103006)Show SMILES CCOC(=O)c1ccc(cc1)-n1c(C)cc(c1C)-c1nnc2CCCCCn12 Show InChI InChI=1S/C22H26N4O2/c1-4-28-22(27)17-9-11-18(12-10-17)26-15(2)14-19(16(26)3)21-24-23-20-8-6-5-7-13-25(20)21/h9-12,14H,4-8,13H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445559
(CHEMBL3102997)Show InChI InChI=1S/C19H21BrN4/c1-13-12-17(14(2)24(13)16-9-7-15(20)8-10-16)19-22-21-18-6-4-3-5-11-23(18)19/h7-10,12H,3-6,11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445519
(CHEMBL3103035)Show SMILES FC(F)(F)c1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C20H18F3N3O/c21-20(22,23)15-5-4-6-16(12-15)26-13-24-17-11-14(7-8-18(17)26)19(27)25-9-2-1-3-10-25/h4-8,11-13H,1-3,9-10H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445535
(CHEMBL3103020)Show SMILES CC(C)C1CCCN(C1)C(=O)c1ccc2n(cnc2c1)-c1cccc(C)c1 Show InChI InChI=1S/C23H27N3O/c1-16(2)19-7-5-11-25(14-19)23(27)18-9-10-22-21(13-18)24-15-26(22)20-8-4-6-17(3)12-20/h4,6,8-10,12-13,15-16,19H,5,7,11,14H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445557
(CHEMBL3102998)Show SMILES Cc1cc(c(C)n1-c1cccc(c1)C(F)(F)F)-c1nnc2CCCCCn12 Show InChI InChI=1S/C20H21F3N4/c1-13-11-17(19-25-24-18-9-4-3-5-10-26(18)19)14(2)27(13)16-8-6-7-15(12-16)20(21,22)23/h6-8,11-12H,3-5,9-10H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50347949
(CHEMBL599406 | US8637558, 46)Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)cc1 |w:7.8,t:1| Show InChI InChI=1S/C18H21NO3S/c20-17-16(23-18(21)19-17)12-14-6-8-15(9-7-14)22-11-10-13-4-2-1-3-5-13/h6-9,12-13H,1-5,10-11H2,(H,19,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of PGDH (unknown origin) |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445512
(CHEMBL3103042)Show SMILES CC(C)(C)c1ccc(cc1)-n1cnc2cc(ccc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C23H27N3O/c1-23(2,3)18-8-10-19(11-9-18)26-16-24-20-15-17(7-12-21(20)26)22(27)25-13-5-4-6-14-25/h7-12,15-16H,4-6,13-14H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445563
(CHEMBL1408258)Show InChI InChI=1S/C19H22N4/c1-14-13-17(15(2)23(14)16-9-5-3-6-10-16)19-21-20-18-11-7-4-8-12-22(18)19/h3,5-6,9-10,13H,4,7-8,11-12H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445510
(CHEMBL3103044)Show InChI InChI=1S/C17H23N3O/c1-2-3-9-20-13-18-15-12-14(7-8-16(15)20)17(21)19-10-5-4-6-11-19/h7-8,12-13H,2-6,9-11H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445518
(CHEMBL3103036)Show SMILES CC(C)c1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C22H25N3O/c1-16(2)17-7-6-8-19(13-17)25-15-23-20-14-18(9-10-21(20)25)22(26)24-11-4-3-5-12-24/h6-10,13-16H,3-5,11-12H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445533
(CHEMBL3103022)Show SMILES Cc1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCC(C1)C(F)(F)F Show InChI InChI=1S/C21H20F3N3O/c1-14-4-2-6-17(10-14)27-13-25-18-11-15(7-8-19(18)27)20(28)26-9-3-5-16(12-26)21(22,23)24/h2,4,6-8,10-11,13,16H,3,5,9,12H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445556
(CHEMBL3102999)Show SMILES Cc1cc(c(C)n1-c1ccc(cc1)C(F)(F)F)-c1nnc2CCCCCn12 Show InChI InChI=1S/C20H21F3N4/c1-13-12-17(19-25-24-18-6-4-3-5-11-26(18)19)14(2)27(13)16-9-7-15(8-10-16)20(21,22)23/h7-10,12H,3-6,11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445534
(CHEMBL3103021)Show SMILES Cc1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCC(C)(C)C1 Show InChI InChI=1S/C22H25N3O/c1-16-6-4-7-18(12-16)25-15-23-19-13-17(8-9-20(19)25)21(26)24-11-5-10-22(2,3)14-24/h4,6-9,12-13,15H,5,10-11,14H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445554
(CHEMBL3103001)Show InChI InChI=1S/C20H21N5/c1-14-11-18(20-23-22-19-9-4-3-5-10-24(19)20)15(2)25(14)17-8-6-7-16(12-17)13-21/h6-8,11-12H,3-5,9-10H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445532
(CHEMBL3103023)Show SMILES Cc1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCC(Br)CC1 Show InChI InChI=1S/C20H20BrN3O/c1-14-3-2-4-17(11-14)24-13-22-18-12-15(5-6-19(18)24)20(25)23-9-7-16(21)8-10-23/h2-6,11-13,16H,7-10H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445513
(CHEMBL3103041)Show SMILES FC(F)(F)c1ccc(cc1)-n1cnc2cc(ccc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C20H18F3N3O/c21-20(22,23)15-5-7-16(8-6-15)26-13-24-17-12-14(4-9-18(17)26)19(27)25-10-2-1-3-11-25/h4-9,12-13H,1-3,10-11H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445552
(CHEMBL3103003)Show InChI InChI=1S/C20H24N4O/c1-14-13-18(20-22-21-19-7-5-4-6-12-23(19)20)15(2)24(14)16-8-10-17(25-3)11-9-16/h8-11,13H,4-7,12H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445553
(CHEMBL3103002)Show InChI InChI=1S/C20H21N5/c1-14-12-18(20-23-22-19-6-4-3-5-11-24(19)20)15(2)25(14)17-9-7-16(13-21)8-10-17/h7-10,12H,3-6,11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445545
(CHEMBL3103010)Show SMILES Cc1cc(c(C)n1-c1cccc2ccccc12)-c1nnc2CCCCCn12 |(30.03,-40.3,;31.5,-39.83,;32.74,-40.74,;33.99,-39.84,;33.52,-38.37,;34.43,-37.13,;31.98,-38.36,;31.24,-37.01,;29.71,-36.99,;28.96,-35.65,;29.76,-34.32,;31.3,-34.35,;32.09,-33.05,;33.62,-33.07,;34.36,-34.42,;33.57,-35.73,;32.04,-35.7,;35.45,-40.32,;35.92,-41.78,;37.46,-41.78,;37.95,-40.31,;39.45,-39.89,;40.05,-38.45,;39.3,-37.09,;37.77,-36.82,;36.61,-37.85,;36.69,-39.41,)| Show InChI InChI=1S/C23H24N4/c1-16-15-20(23-25-24-22-13-4-3-7-14-26(22)23)17(2)27(16)21-12-8-10-18-9-5-6-11-19(18)21/h5-6,8-12,15H,3-4,7,13-14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445551
(CHEMBL3103004)Show SMILES Cc1cc(c(C)n1-c1ccc(cc1)[N+]([O-])=O)-c1nnc2CCCCCn12 Show InChI InChI=1S/C19H21N5O2/c1-13-12-17(19-21-20-18-6-4-3-5-11-22(18)19)14(2)23(13)15-7-9-16(10-8-15)24(25)26/h7-10,12H,3-6,11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445558
(CHEMBL2132150)Show InChI InChI=1S/C19H21FN4/c1-13-12-17(14(2)24(13)16-9-7-15(20)8-10-16)19-22-21-18-6-4-3-5-11-23(18)19/h7-10,12H,3-6,11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 121 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445550
(CHEMBL3103005)Show SMILES Cc1cc(c(C)n1-c1ccc(cc1)C(C)(C)C)-c1nnc2CCCCCn12 Show InChI InChI=1S/C23H30N4/c1-16-15-20(22-25-24-21-9-7-6-8-14-26(21)22)17(2)27(16)19-12-10-18(11-13-19)23(3,4)5/h10-13,15H,6-9,14H2,1-5H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445517
(CHEMBL3103037)Show SMILES CC(C)(C)c1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C23H27N3O/c1-23(2,3)18-8-7-9-19(15-18)26-16-24-20-14-17(10-11-21(20)26)22(27)25-12-5-4-6-13-25/h7-11,14-16H,4-6,12-13H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 171 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445543
(CHEMBL3103012)Show InChI InChI=1S/C18H20N4/c1-13-12-16(14(2)22(13)15-8-4-3-5-9-15)18-20-19-17-10-6-7-11-21(17)18/h3-5,8-9,12H,6-7,10-11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 192 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445542
(CHEMBL3103013)Show InChI InChI=1S/C20H24N4/c1-15-14-18(16(2)24(15)17-10-6-5-7-11-17)20-22-21-19-12-8-3-4-9-13-23(19)20/h5-7,10-11,14H,3-4,8-9,12-13H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 242 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445536
(CHEMBL3103019)Show SMILES CC1CC(C)CN(C1)C(=O)c1ccc2n(cnc2c1)-c1cccc(C)c1 Show InChI InChI=1S/C22H25N3O/c1-15-5-4-6-19(10-15)25-14-23-20-11-18(7-8-21(20)25)22(26)24-12-16(2)9-17(3)13-24/h4-8,10-11,14,16-17H,9,12-13H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 271 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445547
(CHEMBL3103008)Show InChI InChI=1S/C18H21N5/c1-13-11-16(14(2)23(13)15-7-6-9-19-12-15)18-21-20-17-8-4-3-5-10-22(17)18/h6-7,9,11-12H,3-5,8,10H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 271 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445529
(CHEMBL3103026)Show InChI InChI=1S/C19H19N3O/c1-14-5-4-6-16(11-14)22-13-20-17-12-15(7-8-18(17)22)19(23)21-9-2-3-10-21/h4-8,11-13H,2-3,9-10H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 383 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445541
(CHEMBL3103014)Show InChI InChI=1S/C21H26N4/c1-16-15-19(17(2)25(16)18-11-7-6-8-12-18)21-23-22-20-13-9-4-3-5-10-14-24(20)21/h6-8,11-12,15H,3-5,9-10,13-14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 383 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445530
(CHEMBL3103025)Show InChI InChI=1S/C19H21N3O/c1-4-21(5-2)19(23)15-9-10-18-17(12-15)20-13-22(18)16-8-6-7-14(3)11-16/h6-13H,4-5H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 383 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445546
(CHEMBL3103009)Show InChI InChI=1S/C18H21N5/c1-13-12-16(14(2)23(13)15-7-9-19-10-8-15)18-21-20-17-6-4-3-5-11-22(17)18/h7-10,12H,3-6,11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 383 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445528
(CHEMBL3103027)Show SMILES Cc1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCC(C1)c1ccccc1 Show InChI InChI=1S/C26H25N3O/c1-19-7-5-11-23(15-19)29-18-27-24-16-21(12-13-25(24)29)26(30)28-14-6-10-22(17-28)20-8-3-2-4-9-20/h2-5,7-9,11-13,15-16,18,22H,6,10,14,17H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 429 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445540
(CHEMBL3103015)Show InChI InChI=1S/C17H18N4/c1-3-7-15(8-4-1)20-12-10-14(13-20)17-19-18-16-9-5-2-6-11-21(16)17/h1,3-4,7-8,10,12-13H,2,5-6,9,11H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 607 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
Aldehyde dehydrogenase 1A1
(Homo sapiens (Human)) | BDBM50445562
(CHEMBL3102994)Show SMILES Cc1cc(c(C)n1-c1ccc(Cl)c(Cl)c1)-c1nnc2CCCCCn12 Show InChI InChI=1S/C19H20Cl2N4/c1-12-10-15(19-23-22-18-6-4-3-5-9-24(18)19)13(2)25(12)14-7-8-16(20)17(21)11-14/h7-8,10-11H,3-6,9H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 607 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of ALDH1A1 (unknown origin) using NAD+/propionaldehyde as substrate after 15 mins by UV-fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445538
(CHEMBL3103017)Show InChI InChI=1S/C21H20N4/c1-3-9-16(10-4-1)25-15-18(17-11-6-7-12-19(17)25)21-23-22-20-13-5-2-8-14-24(20)21/h1,3-4,6-7,9-12,15H,2,5,8,13-14H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 681 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445527
(CHEMBL3103028)Show InChI InChI=1S/C20H21N3O/c1-14-5-4-8-17(11-14)23-13-21-18-12-15(9-10-19(18)23)20(24)22-16-6-2-3-7-16/h4-5,8-13,16H,2-3,6-7H2,1H3,(H,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 961 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445548
(CHEMBL3103007)Show InChI InChI=1S/C18H21N5/c1-13-12-15(14(2)23(13)16-8-5-6-10-19-16)18-21-20-17-9-4-3-7-11-22(17)18/h5-6,8,10,12H,3-4,7,9,11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
Aldehyde dehydrogenase 1A1
(Homo sapiens (Human)) | BDBM50445514
(CHEMBL3103040 | US11345702, Table 1.33 | US2023039...)Show InChI InChI=1S/C20H21N3O2/c1-25-17-8-6-16(7-9-17)23-14-21-18-13-15(5-10-19(18)23)20(24)22-11-3-2-4-12-22/h5-10,13-14H,2-4,11-12H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of ALDH1A1 (unknown origin) using NAD+/propionaldehyde as substrate after 15 mins by UV-fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445526
(CHEMBL3103029)Show InChI InChI=1S/C19H21N3O/c1-3-4-10-20-19(23)15-8-9-18-17(12-15)21-13-22(18)16-7-5-6-14(2)11-16/h5-9,11-13H,3-4,10H2,1-2H3,(H,20,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445531
(CHEMBL3103024)Show SMILES Cc1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCC(CC1)C(F)(F)F Show InChI InChI=1S/C21H20F3N3O/c1-14-3-2-4-17(11-14)27-13-25-18-12-15(5-6-19(18)27)20(28)26-9-7-16(8-10-26)21(22,23)24/h2-6,11-13,16H,7-10H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
Aldehyde dehydrogenase 1A1
(Homo sapiens (Human)) | BDBM50445557
(CHEMBL3102998)Show SMILES Cc1cc(c(C)n1-c1cccc(c1)C(F)(F)F)-c1nnc2CCCCCn12 Show InChI InChI=1S/C20H21F3N4/c1-13-11-17(19-25-24-18-9-4-3-5-10-26(18)19)14(2)27(13)16-8-6-7-15(12-16)20(21,22)23/h6-8,11-12H,3-5,9-10H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of ALDH1A1 (unknown origin) using NAD+/propionaldehyde as substrate after 15 mins by UV-fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
Aldehyde dehydrogenase 1A1
(Homo sapiens (Human)) | BDBM50445534
(CHEMBL3103021)Show SMILES Cc1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCC(C)(C)C1 Show InChI InChI=1S/C22H25N3O/c1-16-6-4-7-18(12-16)25-15-23-19-13-17(8-9-20(19)25)21(26)24-11-5-10-22(2,3)14-24/h4,6-9,12-13,15H,5,10-11,14H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of ALDH1A1 (unknown origin) using NAD+/propionaldehyde as substrate after 15 mins by UV-fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
Aldehyde dehydrogenase 1A1
(Homo sapiens (Human)) | BDBM50445521
(CHEMBL3103033 | US11345702, Table 1.21 | US2023039...)Show InChI InChI=1S/C19H18ClN3O/c20-15-5-4-6-16(12-15)23-13-21-17-11-14(7-8-18(17)23)19(24)22-9-2-1-3-10-22/h4-8,11-13H,1-3,9-10H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of ALDH1A1 (unknown origin) using NAD+/propionaldehyde as substrate after 15 mins by UV-fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
Aldehyde dehydrogenase 1A1
(Homo sapiens (Human)) | BDBM50445555
(CHEMBL3103000)Show InChI InChI=1S/C20H24N4/c1-14-8-10-17(11-9-14)24-15(2)13-18(16(24)3)20-22-21-19-7-5-4-6-12-23(19)20/h8-11,13H,4-7,12H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of ALDH1A1 (unknown origin) using NAD+/propionaldehyde as substrate after 15 mins by UV-fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
Aldehyde dehydrogenase 1A1
(Homo sapiens (Human)) | BDBM50445519
(CHEMBL3103035)Show SMILES FC(F)(F)c1cccc(c1)-n1cnc2cc(ccc12)C(=O)N1CCCCC1 Show InChI InChI=1S/C20H18F3N3O/c21-20(22,23)15-5-4-6-16(12-15)26-13-24-17-11-14(7-8-18(17)26)19(27)25-9-2-1-3-10-25/h4-8,11-13H,1-3,9-10H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of ALDH1A1 (unknown origin) using NAD+/propionaldehyde as substrate after 15 mins by UV-fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50049243
(5-[4-(1-Methyl-cyclohexylmethoxy)-benzyl]-thiazoli...)Show InChI InChI=1S/C18H23NO3S/c1-18(9-3-2-4-10-18)12-22-14-7-5-13(6-8-14)11-15-16(20)19-17(21)23-15/h5-8,20H,2-4,9-12H2,1H3,(H,19,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of PGDH (unknown origin) |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445525
(CHEMBL3103030)Show SMILES CN1CCN(CC1)C(=O)c1ccc2n(cnc2c1)-c1cccc(C)c1 Show InChI InChI=1S/C20H22N4O/c1-15-4-3-5-17(12-15)24-14-21-18-13-16(6-7-19(18)24)20(25)23-10-8-22(2)9-11-23/h3-7,12-14H,8-11H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445524
(CHEMBL3103031)Show InChI InChI=1S/C19H19N3O2/c1-14-3-2-4-16(11-14)22-13-20-17-12-15(5-6-18(17)22)19(23)21-7-9-24-10-8-21/h2-6,11-13H,7-10H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445544
(CHEMBL3103011)Show InChI InChI=1S/C17H18N4/c1-12-11-15(17-19-18-16-9-6-10-20(16)17)13(2)21(12)14-7-4-3-5-8-14/h3-5,7-8,11H,6,9-10H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
(Homo sapiens (Human)) | BDBM50445539
(CHEMBL3103016)Show InChI InChI=1S/C16H17N5/c1-3-7-13(8-4-1)21-12-10-14(19-21)16-18-17-15-9-5-2-6-11-20(15)16/h1,3-4,7-8,10,12H,2,5-6,9,11H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
Aldehyde dehydrogenase 1A1
(Homo sapiens (Human)) | BDBM50445561
(CHEMBL3102995)Show InChI InChI=1S/C19H21ClN4/c1-13-11-17(14(2)24(13)16-8-6-7-15(20)12-16)19-22-21-18-9-4-3-5-10-23(18)19/h6-8,11-12H,3-5,9-10H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of ALDH1A1 (unknown origin) using NAD+/propionaldehyde as substrate after 15 mins by UV-fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
Aldehyde dehydrogenase 1A1
(Homo sapiens (Human)) | BDBM50445554
(CHEMBL3103001)Show InChI InChI=1S/C20H21N5/c1-14-11-18(20-23-22-19-9-4-3-5-10-24(19)20)15(2)25(14)17-8-6-7-16(12-17)13-21/h6-8,11-12H,3-5,9-10H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences
Curated by ChEMBL
| Assay Description
Inhibition of ALDH1A1 (unknown origin) using NAD+/propionaldehyde as substrate after 15 mins by UV-fluorescence assay |
Bioorg Med Chem Lett 24: 630-5 (2014)
Article DOI: 10.1016/j.bmcl.2013.11.081
BindingDB Entry DOI: 10.7270/Q28G8N6H |
More data for this
Ligand-Target Pair | |
Search and Browse
