Affinity Data by PubMed id=26247308

PubMed code 26247308

Found 20 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152653 (4-(1,3-Dioxoisoindolin-2-yl)-N-(4-ethylphenyl)benz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.82E+4	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152639 (4-(1,3-Dioxoisoindolin-2-yl)-N,N-dimethyl benzenes...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152644 (4-(1,3-Dioxoisoindolin-2-yl)-N-phenylbenzenesulpho...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152651 (4-(1,3-Dioxoisoindolin-2-yl)-N-m-tolylbenzenesulph...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152655 (4-(4-(1,3-Dioxoisoindolin-2-yl)phenylsulphonamido)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152643 (2-(4-(4-Methylpiperazin-1-ylsulphonyl)phenyl)isoin...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152648 (N-(3-chlorophenyl)-4-(1,3-dioxoisoindolin-2-yl)ben...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152649 (N-(4-chlorophenyl)-4-(1,3-dioxoisoindolin-2-yl)ben...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152650 (4-(1,3-Dioxoisoindolin-2-yl)-N-o-tolylbenzenesulph...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152647 (4-(1,3-Dioxoisoindolin-2-yl)-N-(4-methoxyphenyl)be...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152652 (4-(1,3-Dioxoisoindolin-2-yl)-N-p-tolylbenzenesulph...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152657 (4-(1,3-Dioxoisoindolin-2-yl)-N-phenethylbenzenesul...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152646 (4-(1,3-Dioxoisoindolin-2-yl)-N-(3-methoxyphenyl)be...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152640 (4-(1,3-Dioxoisoindolin-2-yl)-N,N-diethyl benzenesu...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152642 (2-(4-(Piperidin-1-ylsulphonyl)phenyl)isoindoline-1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152654 (4-(1,3-Dioxoisoindolin-2-yl)-N-(4-nitrophenyl)benz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152645 (4-(1,3-Dioxoisoindolin-2-yl)-N-(2-hydroxyphenyl)be...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152640 (4-(1,3-Dioxoisoindolin-2-yl)-N,N-diethyl benzenesu...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152638 (4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1C(=O)c2ccccc2C1=O Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair
Genome polyprotein (Dengue virus 2 (Virus))	BDBM152656 (4-(1,3-Dioxoisoindolin-2-yl)-N-(naphthalen-1-yl)be...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+5	n/a	n/a	n/a	n/a	8.5	n/a
Birla Institute of Technology					Assay Description To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...				Bioorg Chem 62: 74-82 (2015) Article DOI: 10.1016/j.bioorg.2015.07.005 BindingDB Entry DOI: 10.7270/Q2VT1QTG
Birla Institute of Technology					More data for this Ligand-Target Pair

* indicates data uncertainty>20%