Affinity Data by PubMed id=26270568

PubMed code 26270568

Found 18 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50115491 (CHEMBL3608988) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin)				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50115492 (CHEMBL3608989) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin)				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50307871 ((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin)				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prothrombin (Homo sapiens (Human))	BDBM50037981 (CHEMBL103102 \| CHEMBL216318 \| Piperidine-1-carboxa...) Show SMILES NC(=N)N1CCCCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	1.11E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin)				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50038002 (Benzamidine (Protonated) \| CHEMBL20936 \| CHEMBL537...) Show SMILES NC(=N)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	2.58E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin)				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50115490 (CHEMBL3608990) Show SMILES NC(=O)c1ccc(Cl)s1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	4.31E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin)				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50115489 (CHEMBL1571193) Show SMILES COc1ccc(cc1)C(=O)Nc1ccccn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	2.43E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin)				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50115489 (CHEMBL1571193) Show SMILES COc1ccc(cc1)C(=O)Nc1ccccn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetry				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50115489 (CHEMBL1571193) Show SMILES COc1ccc(cc1)C(=O)Nc1ccccn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	1.58E+6	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin) by displacement titration based isothermal titration colorimetry				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50037981 (CHEMBL103102 \| CHEMBL216318 \| Piperidine-1-carboxa...) Show SMILES NC(=N)N1CCCCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	1.97E+5	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin) by displacement titration based isothermal titration colorimetry				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50307871 ((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetry				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prothrombin (Homo sapiens (Human))	BDBM50115490 (CHEMBL3608990) Show SMILES NC(=O)c1ccc(Cl)s1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	4.75E+5	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetry				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50115490 (CHEMBL3608990) Show SMILES NC(=O)c1ccc(Cl)s1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	5.07E+5	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin) by displacement titration based isothermal titration colorimetry				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50115491 (CHEMBL3608988) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetry				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50038002 (Benzamidine (Protonated) \| CHEMBL20936 \| CHEMBL537...) Show SMILES NC(=N)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	4.55E+5	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin) by displacement titration based isothermal titration colorimetry				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50115492 (CHEMBL3608989) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetry				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50038002 (Benzamidine (Protonated) \| CHEMBL20936 \| CHEMBL537...) Show SMILES NC(=N)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	3.55E+5	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetry				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50037981 (CHEMBL103102 \| CHEMBL216318 \| Piperidine-1-carboxa...) Show SMILES NC(=N)N1CCCCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	1.07E+5	n/a	n/a	n/a	n/a	n/a
Philipps-University Marburg Curated by ChEMBL					Assay Description Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetry				J Med Chem 58: 6960-71 (2015) Article DOI: 10.1021/acs.jmedchem.5b00812 BindingDB Entry DOI: 10.7270/Q26M38M6
Philipps-University Marburg Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%