Affinity Data by PubMed id=26301559

PubMed code 26301559

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM50422013 (LOBELINE \| Lobeline Hydrochloride) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity to alpha4beta2 (unknown origin)				Eur J Med Chem 102: 425-44 (2015) Article DOI: 10.1016/j.ejmech.2015.07.024 BindingDB Entry DOI: 10.7270/Q2765H4R
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM50422013 (LOBELINE \| Lobeline Hydrochloride) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity to alpha4beta2 (unknown origin)				Eur J Med Chem 102: 425-44 (2015) Article DOI: 10.1016/j.ejmech.2015.07.024 BindingDB Entry DOI: 10.7270/Q2765H4R
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine-binding protein (Lymnaea stagnalis)	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 \|r\| Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity to Lymnaea stagnalis AChBP after 300 seconds by SPR biosensor analysis				Eur J Med Chem 102: 425-44 (2015) Article DOI: 10.1016/j.ejmech.2015.07.024 BindingDB Entry DOI: 10.7270/Q2765H4R
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetylcholine-binding protein (Lymnaea stagnalis)	BDBM50120209 (CHEMBL3616575) Show SMILES C(N1CCCN(CC1)c1cccnc1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity to Lymnaea stagnalis AChBP after 300 seconds by SPR biosensor analysis				Eur J Med Chem 102: 425-44 (2015) Article DOI: 10.1016/j.ejmech.2015.07.024 BindingDB Entry DOI: 10.7270/Q2765H4R
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine-binding protein (Lymnaea stagnalis)	BDBM50120210 (CHEMBL3616577) Show SMILES C(CN1CCCN(CC1)c1cccnc1)Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity to Lymnaea stagnalis AChBP after 300 seconds by SPR biosensor analysis				Eur J Med Chem 102: 425-44 (2015) Article DOI: 10.1016/j.ejmech.2015.07.024 BindingDB Entry DOI: 10.7270/Q2765H4R
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine-binding protein (Lymnaea stagnalis)	BDBM50120209 (CHEMBL3616575) Show SMILES C(N1CCCN(CC1)c1cccnc1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity to Lymnaea stagnalis AChBP after 300 seconds by SPR biosensor analysis				Eur J Med Chem 102: 425-44 (2015) Article DOI: 10.1016/j.ejmech.2015.07.024 BindingDB Entry DOI: 10.7270/Q2765H4R
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine-binding protein (Lymnaea stagnalis)	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 \|r\| Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity to Lymnaea stagnalis AChBP after 300 seconds by SPR biosensor analysis				Eur J Med Chem 102: 425-44 (2015) Article DOI: 10.1016/j.ejmech.2015.07.024 BindingDB Entry DOI: 10.7270/Q2765H4R
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetylcholine-binding protein (Lymnaea stagnalis)	BDBM50422013 (LOBELINE \| Lobeline Hydrochloride) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity to Lymnaea stagnalis AChBP after 300 seconds by SPR biosensor analysis				Eur J Med Chem 102: 425-44 (2015) Article DOI: 10.1016/j.ejmech.2015.07.024 BindingDB Entry DOI: 10.7270/Q2765H4R
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine-binding protein (Lymnaea stagnalis)	BDBM50120210 (CHEMBL3616577) Show SMILES C(CN1CCCN(CC1)c1cccnc1)Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity to Lymnaea stagnalis AChBP after 300 seconds by SPR biosensor analysis				Eur J Med Chem 102: 425-44 (2015) Article DOI: 10.1016/j.ejmech.2015.07.024 BindingDB Entry DOI: 10.7270/Q2765H4R
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholine-binding protein (Lymnaea stagnalis)	BDBM50422013 (LOBELINE \| Lobeline Hydrochloride) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity to Lymnaea stagnalis AChBP after 300 seconds by SPR biosensor analysis				Eur J Med Chem 102: 425-44 (2015) Article DOI: 10.1016/j.ejmech.2015.07.024 BindingDB Entry DOI: 10.7270/Q2765H4R
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%