Found 68 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret S891A mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50134785
(CHEMBL3753512)Show InChI InChI=1S/C17H20N6O/c18-16-14-15(12-8-13(24-22-12)10-6-7-10)21-23(17(14)20-9-19-16)11-4-2-1-3-5-11/h8-11H,1-7H2,(H2,18,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret Y791F mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50021574
(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC Show InChI InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret S891A mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50134786
(CHEMBL3751904)Show InChI InChI=1S/C16H18N6O2/c17-15-13-14(11-7-12(24-21-11)9-1-2-9)20-22(16(13)19-8-18-15)10-3-5-23-6-4-10/h7-10H,1-6H2,(H2,17,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret M918T mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50021574
(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC Show InChI InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret Y791F mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret G691S mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50388620
(CHEMBL2058538)Show InChI InChI=1S/C16H15N5/c1-11(2)21-16-14(15(17)18-10-19-16)13(20-21)9-8-12-6-4-3-5-7-12/h3-7,10-11H,1-2H3,(H2,17,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret Y791F mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50134785
(CHEMBL3753512)Show InChI InChI=1S/C17H20N6O/c18-16-14-15(12-8-13(24-22-12)10-6-7-10)21-23(17(14)20-9-19-16)11-4-2-1-3-5-11/h8-11H,1-7H2,(H2,18,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50021574
(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC Show InChI InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret G691S mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50021574
(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC Show InChI InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret M918T mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804L mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase beta-1
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of recombinant human p70S6K by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136293
(CHEMBL3752118)Show InChI InChI=1S/C12H12N6O/c1-18-12-9(11(13)14-5-15-12)10(16-18)7-4-8(19-17-7)6-2-3-6/h4-6H,2-3H2,1H3,(H2,13,14,15) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50134786
(CHEMBL3751904)Show InChI InChI=1S/C16H18N6O2/c17-15-13-14(11-7-12(24-21-11)9-1-2-9)20-22(16(13)19-8-18-15)10-3-5-23-6-4-10/h7-10H,1-6H2,(H2,17,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136227
(CHEMBL3753958)Show InChI InChI=1S/C13H16N6O/c1-4-8-5-9(18-20-8)11-10-12(14)15-6-16-13(10)19(17-11)7(2)3/h5-7H,4H2,1-3H3,(H2,14,15,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136224
(CHEMBL3752395)Show InChI InChI=1S/C14H18N6O/c1-7(2)10-5-9(19-21-10)12-11-13(15)16-6-17-14(11)20(18-12)8(3)4/h5-8H,1-4H3,(H2,15,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136294
(CHEMBL3752879)Show InChI InChI=1S/C11H10N6O/c12-10-8-9(15-16-11(8)14-4-13-10)6-3-7(18-17-6)5-1-2-5/h3-5H,1-2H2,(H3,12,13,14,15,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50388620
(CHEMBL2058538)Show InChI InChI=1S/C16H15N5/c1-11(2)21-16-14(15(17)18-10-19-16)13(20-21)9-8-12-6-4-3-5-7-12/h3-7,10-11H,1-2H3,(H2,17,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret S891A mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50388620
(CHEMBL2058538)Show InChI InChI=1S/C16H15N5/c1-11(2)21-16-14(15(17)18-10-19-16)13(20-21)9-8-12-6-4-3-5-7-12/h3-7,10-11H,1-2H3,(H2,17,18,19) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret M918T mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase Fgr
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB
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UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of recombinant human FGR by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136229
(CHEMBL3752712)Show InChI InChI=1S/C15H18N6O2/c1-15(2,22)6-21-14-11(13(16)17-7-18-14)12(19-21)9-5-10(23-20-9)8-3-4-8/h5,7-8,22H,3-4,6H2,1-2H3,(H2,16,17,18) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of recombinant human FLT4 by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136235
(CHEMBL3754346)Show InChI InChI=1S/C18H16N6O/c19-17-15-16(13-8-14(25-23-13)12-6-7-12)22-24(18(15)21-10-20-17)9-11-4-2-1-3-5-11/h1-5,8,10,12H,6-7,9H2,(H2,19,20,21) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50388620
(CHEMBL2058538)Show InChI InChI=1S/C16H15N5/c1-11(2)21-16-14(15(17)18-10-19-16)13(20-21)9-8-12-6-4-3-5-7-12/h3-7,10-11H,1-2H3,(H2,17,18,19) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret G691S mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Dual specificity mitogen-activated protein kinase kinase 2
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of recombinant human MEK2 by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of recombinant human VGFR2 by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136232
(CHEMBL3753242)Show InChI InChI=1S/C18H24N6O/c1-2-3-4-5-6-9-24-18-15(17(19)20-11-21-18)16(22-24)13-10-14(25-23-13)12-7-8-12/h10-12H,2-9H2,1H3,(H2,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase HCK
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 137 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of recombinant human HCK by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 142 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of recombinant human MEK1 by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136236
(CHEMBL3754092)Show SMILES CC(C)n1nc(-c2cc(on2)-c2ccc(F)cc2)c2c(N)ncnc12 Show InChI InChI=1S/C17H15FN6O/c1-9(2)24-17-14(16(19)20-8-21-17)15(22-24)12-7-13(25-23-12)10-3-5-11(18)6-4-10/h3-9H,1-2H3,(H2,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136293
(CHEMBL3752118)Show InChI InChI=1S/C12H12N6O/c1-18-12-9(11(13)14-5-15-12)10(16-18)7-4-8(19-17-7)6-2-3-6/h4-6H,2-3H2,1H3,(H2,13,14,15) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 182 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136295
(CHEMBL3754442)Show InChI InChI=1S/C17H16N6O/c1-10(2)23-17-14(16(18)19-9-20-17)15(21-23)12-8-13(24-22-12)11-6-4-3-5-7-11/h3-10H,1-2H3,(H2,18,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136223
(CHEMBL3751965)Show InChI InChI=1S/C15H20N6O/c1-8(2)21-14-11(13(16)17-7-18-14)12(19-21)9-6-10(22-20-9)15(3,4)5/h6-8H,1-5H3,(H2,16,17,18) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136290
(CHEMBL3752025)Show InChI InChI=1S/C11H12N6O/c1-6(2)17-11-8(10(12)13-5-14-11)9(15-17)7-3-4-18-16-7/h3-6H,1-2H3,(H2,12,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 213 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136229
(CHEMBL3752712)Show InChI InChI=1S/C15H18N6O2/c1-15(2,22)6-21-14-11(13(16)17-7-18-14)12(19-21)9-5-10(23-20-9)8-3-4-8/h5,7-8,22H,3-4,6H2,1-2H3,(H2,16,17,18) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 217 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50021574
(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC Show InChI InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804L mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136225
(CHEMBL3753903)Show InChI InChI=1S/C16H20N6O/c1-9(2)22-16-13(15(17)18-8-19-16)14(20-22)11-7-12(23-21-11)10-5-3-4-6-10/h7-10H,3-6H2,1-2H3,(H2,17,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 241 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50134789
(CHEMBL3753714)Show InChI InChI=1S/C18H18N6O/c1-11(2)24-18-15(17(19)20-10-21-18)16(22-24)14-9-13(25-23-14)8-12-6-4-3-5-7-12/h3-7,9-11H,8H2,1-2H3,(H2,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 241 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 311 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of recombinant human RSK1 by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136294
(CHEMBL3752879)Show InChI InChI=1S/C11H10N6O/c12-10-8-9(15-16-11(8)14-4-13-10)6-3-7(18-17-6)5-1-2-5/h3-5H,1-2H2,(H3,12,13,14,15,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 354 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136224
(CHEMBL3752395)Show InChI InChI=1S/C14H18N6O/c1-7(2)10-5-9(19-21-10)12-11-13(15)16-6-17-14(11)20(18-12)8(3)4/h5-8H,1-4H3,(H2,15,16,17) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 355 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50021574
(BMS-907351 | CABOZANTINIB | CHEBI:72317 | Cabomety...)Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC Show InChI InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 358 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136227
(CHEMBL3753958)Show InChI InChI=1S/C13H16N6O/c1-4-8-5-9(18-20-8)11-10-12(14)15-6-16-13(10)19(17-11)7(2)3/h5-7H,4H2,1-3H3,(H2,14,15,16) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 531 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136235
(CHEMBL3754346)Show InChI InChI=1S/C18H16N6O/c19-17-15-16(13-8-14(25-23-13)12-6-7-12)22-24(18(15)21-10-20-17)9-11-4-2-1-3-5-11/h1-5,8,10,12H,6-7,9H2,(H2,19,20,21) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 557 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50134788
(CHEMBL3752736)Show SMILES CC(C)n1nc(C2=NOC(C2)c2ccccc2)c2c(N)ncnc12 |t:6| Show InChI InChI=1S/C17H18N6O/c1-10(2)23-17-14(16(18)19-9-20-17)15(21-23)12-8-13(24-22-12)11-6-4-3-5-7-11/h3-7,9-10,13H,8H2,1-2H3,(H2,18,19,20) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 583 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136290
(CHEMBL3752025)Show InChI InChI=1S/C11H12N6O/c1-6(2)17-11-8(10(12)13-5-14-11)9(15-17)7-3-4-18-16-7/h3-6H,1-2H3,(H2,12,13,14) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 903 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136291
(CHEMBL3752827)Show InChI InChI=1S/C17H22N6O/c1-10(2)23-17-14(16(18)19-9-20-17)15(21-23)12-8-13(24-22-12)11-6-4-3-5-7-11/h8-11H,3-7H2,1-2H3,(H2,18,19,20) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50134790
(CHEMBL3754247)Show InChI InChI=1S/C16H15N7O/c1-9(2)23-16-13(15(17)19-8-20-16)14(21-23)11-7-12(24-22-11)10-5-3-4-6-18-10/h3-9H,1-2H3,(H2,17,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136232
(CHEMBL3753242)Show InChI InChI=1S/C18H24N6O/c1-2-3-4-5-6-9-24-18-15(17(19)20-11-21-18)16(22-24)13-10-14(25-23-13)12-7-8-12/h10-12H,2-9H2,1H3,(H2,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 927 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136225
(CHEMBL3753903)Show InChI InChI=1S/C16H20N6O/c1-9(2)22-16-13(15(17)18-8-19-16)14(20-22)11-7-12(23-21-11)10-5-3-4-6-10/h7-10H,3-6H2,1-2H3,(H2,17,18,19) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50134789
(CHEMBL3753714)Show InChI InChI=1S/C18H18N6O/c1-11(2)24-18-15(17(19)20-10-21-18)16(22-24)14-9-13(25-23-14)8-12-6-4-3-5-7-12/h3-7,9-11H,8H2,1-2H3,(H2,19,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Cytochrome P450 1A2
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of CYP1A2 (unknown origin) |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136223
(CHEMBL3751965)Show InChI InChI=1S/C15H20N6O/c1-8(2)21-14-11(13(16)17-7-18-14)12(19-21)9-6-10(22-20-9)15(3,4)5/h6-8H,1-5H3,(H2,16,17,18) | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50388620
(CHEMBL2058538)Show InChI InChI=1S/C16H15N5/c1-11(2)21-16-14(15(17)18-10-19-16)13(20-21)9-8-12-6-4-3-5-7-12/h3-7,10-11H,1-2H3,(H2,17,18,19) | PDB MMDB
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B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50388620
(CHEMBL2058538)Show InChI InChI=1S/C16H15N5/c1-11(2)21-16-14(15(17)18-10-19-16)13(20-21)9-8-12-6-4-3-5-7-12/h3-7,10-11H,1-2H3,(H2,17,18,19) | PDB MMDB
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UniProtKB/SwissProt
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804L mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50134787
(CHEMBL3753503)Show InChI InChI=1S/C9H12N6O/c1-5(2)15-9-7(6(14-15)3-13-16)8(10)11-4-12-9/h3-5,16H,1-2H3,(H2,10,11,12)/b13-3+ | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50134787
(CHEMBL3753503)Show InChI InChI=1S/C9H12N6O/c1-5(2)15-9-7(6(14-15)3-13-16)8(10)11-4-12-9/h3-5,16H,1-2H3,(H2,10,11,12)/b13-3+ | PDB MMDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50134788
(CHEMBL3752736)Show SMILES CC(C)n1nc(C2=NOC(C2)c2ccccc2)c2c(N)ncnc12 |t:6| Show InChI InChI=1S/C17H18N6O/c1-10(2)23-17-14(16(18)19-9-20-17)15(21-23)12-8-13(24-22-12)11-6-4-3-5-7-11/h3-7,9-10,13H,8H2,1-2H3,(H2,18,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50134790
(CHEMBL3754247)Show InChI InChI=1S/C16H15N7O/c1-9(2)23-16-13(15(17)19-8-20-16)14(21-23)11-7-12(24-22-11)10-5-3-4-6-18-10/h3-9H,1-2H3,(H2,17,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human)) | BDBM50136292
(CHEMBL3754195)Show InChI InChI=1S/C16H18N6O/c1-11(2)22-16-14(15(17)18-10-19-16)13(21-22)8-20-23-9-12-6-4-3-5-7-12/h3-8,10-11H,9H2,1-2H3,(H2,17,18,19)/b20-8+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATP |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of CYP3A4 (unknown origin) |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of CYP2D6 (unknown origin) |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of CYP2C9 (unknown origin) |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50136226
(CHEMBL3753341)Show InChI InChI=1S/C14H16N6O/c1-7(2)20-14-11(13(15)16-6-17-14)12(18-20)9-5-10(21-19-9)8-3-4-8/h5-8H,3-4H2,1-2H3,(H2,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST)
Curated by ChEMBL
| Assay Description Inhibition of CYP2C19 (unknown origin) |
J Med Chem 59: 358-73 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01522 BindingDB Entry DOI: 10.7270/Q2VD719M |
More data for this Ligand-Target Pair | |