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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178123 ((2'R*,7R*)-3-(4-methoxybenzyl)-3,5,6,7-tetrahy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178112 (3-(4-fluorobenzyl)-5,6-dihydrospiro[benzo[d][1,2,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178114 (3-(4-(trifluoromethyl)benzyl)-5,6-dihydrospiro[ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 440 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178115 (3-(4-methoxybenzyl)-5,6-dihydrospiro[benzo[d][1,2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178113 (3-(4-chlorobenzyl)-5,6-dihydrospiro[benzo[d][1,2,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178111 (3-(naphthalen-2-ylmethyl)-5,6-dihydrospiro[benzo[d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 590 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178128 (isobutyl ((2'R*,7R*)-3-(4-methoxybenzyl)-3,5,6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178125 ((2'R*,7R*)-3-(4-methoxybenzyl)-3,5,6,7-tetrahy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178121 ((2'R*,7R*)-3-benzyl-3,5,6,7-tetrahydrospiro [b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 780 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178117 ((2'R*,7R*)-3-(4-methoxybenzyl)-3,5,6,7-tetrahy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 930 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178127 ((2'R*,7R*)-3-(4-methoxybenzyl)-3,5,6,7-tetrahy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 990 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178110 (3-((7-oxo-6,7-dihydrospiro[benzo[d][1,2,3]triazole...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178126 ((2'R*,7S*)-3-(4-methoxybenzyl)-3,5,6,7-tetrahy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.21E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178119 ((2'R*,7R*)-3-benzyl-3,5,6,7-tetrahydrospiro [b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178109 (3-(2-methylbenzyl)-5,6-dihydrospiro[benzo[d][1,2,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178108 (3-benzyl-5,6-dihydrospiro[benzo[d][1,2,3]triazole-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178118 ((2'R*,7S*)-3-(4-methoxybenzyl)-3,5,6,7-tetrahy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178130 ((4R,7S)-3-[(4-methoxyphenyl)methyl]-3,5,6,7-tetrah...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178122 ((2'R*,7S*)-3-benzyl-3,5,6,7-tetrahydrospiro [b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178129 ((4S,7S)-3-[(4-methoxyphenyl)methyl]-3,5,6,7-tetrah...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178120 ((2'R*,7S*)-3-benzyl-3,5,6,7-tetrahydrospiro [b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178116 (1-[(4-methoxyphenyl)methyl]-7-methylidene-4,5,6,7-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178124 ((2'R*,7S*)-3-(4-methoxybenzyl)-3,5,6,7-tetrahy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM178107 (3-(cyclohexylmethyl)-5,6-dihydrospiro[benzo[d][1,2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
German Cancer Research Center (DKFZ) | Assay Description Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total... | ACS Chem Biol 11: 1001-11 (2016) Article DOI: 10.1021/acschembio.5b00755 BindingDB Entry DOI: 10.7270/Q23J3BQR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
