Affinity Data by PubMed id=26965864

PubMed code 26965864

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50155759 (CHEMBL3781453) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Lucknow Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assay				Bioorg Med Chem Lett 26: 1988-92 (2016) Article DOI: 10.1016/j.bmcl.2016.03.003 BindingDB Entry DOI: 10.7270/Q2514147
University of Lucknow Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50155760 (CHEMBL3780639) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Lucknow Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assay				Bioorg Med Chem Lett 26: 1988-92 (2016) Article DOI: 10.1016/j.bmcl.2016.03.003 BindingDB Entry DOI: 10.7270/Q2514147
University of Lucknow Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50155761 (CHEMBL3782051) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Lucknow Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assay				Bioorg Med Chem Lett 26: 1988-92 (2016) Article DOI: 10.1016/j.bmcl.2016.03.003 BindingDB Entry DOI: 10.7270/Q2514147
University of Lucknow Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50155762 (CHEMBL3781672) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Lucknow Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assay				Bioorg Med Chem Lett 26: 1988-92 (2016) Article DOI: 10.1016/j.bmcl.2016.03.003 BindingDB Entry DOI: 10.7270/Q2514147
University of Lucknow Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50155758 (Imbricatolic Acid) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Lucknow Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP-1B using IR5 insulin receptor residues as substrate after 30 mins by malachite green assay				Bioorg Med Chem Lett 26: 1988-92 (2016) Article DOI: 10.1016/j.bmcl.2016.03.003 BindingDB Entry DOI: 10.7270/Q2514147
University of Lucknow Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%