Affinity Data by PubMed id=27031216

PubMed code 27031216

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nischarin (RAT)	BDBM50164835 (CHEMBL3800398) Show SMILES Cl.Fc1ccc2n(CC3=NCCN3)ccc2c1 \|t:7\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164841 (CHEMBL3798191) Show SMILES Cl.Brc1cccc2ccn(CC3=NCCN3)c12 \|t:10\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164834 (CHEMBL3798638) Show SMILES Cl.Brc1cccc2n(CC3=NCCN3)ccc12 \|t:8\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	468	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164837 (CHEMBL3800446) Show SMILES Cl.Fc1ccc2ccn(CC3=NCCN3)c2c1 \|t:9\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	789	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164842 (CHEMBL3798387) Show SMILES Br.Cc1cccc2ccn(CC3=NCCN3)c12 \|t:10\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164838 (CHEMBL3797854) Show SMILES Cl.Clc1ccc2ccn(CC3=NCCN3)c2c1 \|t:9\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164839 (CHEMBL3797661) Show SMILES Cl.Fc1cccc2ccn(CC3=NCCN3)c12 \|t:10\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164840 (CHEMBL3799780) Show SMILES Cl.Clc1cccc2ccn(CC3=NCCN3)c12 \|t:10\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164836 (CHEMBL3798967) Show SMILES Cl.Brc1ccc2n(CC3=NCCN3)ccc2c1 \|t:7\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164833 (CHEMBL3799346) Show SMILES Cl.Fc1cccc2n(CC3=NCCN3)ccc12 \|t:8\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164845 (CHEMBL3799081) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.63E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164843 (CHEMBL3800486) Show SMILES Cl.CCc1cccc2ccn(CC3=NCCN3)c12 \|t:11\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.58E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164832 (CHEMBL3797481) Show SMILES Cl.C(C1=NCCN1)n1ccc2ccccc12 \|t:1\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.14E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair
Nischarin (RAT)	BDBM50164844 (CHEMBL3798276) Show SMILES Br.COc1cccc2ccn(CC3=NCCN3)c12 \|t:11\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.88E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from Imidazoline receptor 1 in Sprague-Dawley rat kidney P2 membranes after 45 hrs by liquid scintillation counting				Eur J Med Chem 115: 406-15 (2016) Article DOI: 10.1016/j.ejmech.2016.03.026 BindingDB Entry DOI: 10.7270/Q2GH9KVS
Medical University of Gdansk Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%