Found 11 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human)) | BDBM50209096
(CHEMBL3885080)Show SMILES CC[C@H](C)N1C(=O)C2(CC2)c2cnc(Nc3cccnc3)nc12 |r| Show InChI InChI=1S/C17H19N5O/c1-3-11(2)22-14-13(17(6-7-17)15(22)23)10-19-16(21-14)20-12-5-4-8-18-9-12/h4-5,8-11H,3,6-7H2,1-2H3,(H,19,20,21)/t11-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of MARK3 (unknown origin) |
Bioorg Med Chem Lett 27: 109-113 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.066
BindingDB Entry DOI: 10.7270/Q20867B1 |
More data for this
Ligand-Target Pair | |
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human)) | BDBM50208926
(CHEMBL3884179)Show SMILES C[C@H](N1C(=O)C(C)(C)c2cnc(Nc3cccnc3)nc12)c1ccc(F)cc1 |r| Show InChI InChI=1S/C21H20FN5O/c1-13(14-6-8-15(22)9-7-14)27-18-17(21(2,3)19(27)28)12-24-20(26-18)25-16-5-4-10-23-11-16/h4-13H,1-3H3,(H,24,25,26)/t13-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of MARK3 (unknown origin) |
Bioorg Med Chem Lett 27: 109-113 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.066
BindingDB Entry DOI: 10.7270/Q20867B1 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human)) | BDBM50209077
(CHEMBL3884116)Show SMILES CC[C@H](C)N1C(=O)C(C)(C)c2cnc(Nc3ccc(cc3)-c3nnc(C)[nH]3)nc12 |r| Show InChI InChI=1S/C21H25N7O/c1-6-12(2)28-18-16(21(4,5)19(28)29)11-22-20(25-18)24-15-9-7-14(8-10-15)17-23-13(3)26-27-17/h7-12H,6H2,1-5H3,(H,22,24,25)(H,23,26,27)/t12-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of MARK3 (unknown origin) |
Bioorg Med Chem Lett 27: 109-113 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.066
BindingDB Entry DOI: 10.7270/Q20867B1 |
More data for this
Ligand-Target Pair | |
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human)) | BDBM50208922
(CHEMBL3884253)Show SMILES CC[C@H](C)N1C(=O)C(C)(C)c2cnc(Nc3cccnc3)nc12 |r| Show InChI InChI=1S/C17H21N5O/c1-5-11(2)22-14-13(17(3,4)15(22)23)10-19-16(21-14)20-12-7-6-8-18-9-12/h6-11H,5H2,1-4H3,(H,19,20,21)/t11-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of MARK3 (unknown origin) |
Bioorg Med Chem Lett 27: 109-113 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.066
BindingDB Entry DOI: 10.7270/Q20867B1 |
More data for this
Ligand-Target Pair | |
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human)) | BDBM50209079
(CHEMBL3885363)Show SMILES CC[C@H](C)N1C(=O)C(C)(C)c2cnc(Nc3ccc(cc3)S(C)(=O)=O)nc12 |r| Show InChI InChI=1S/C19H24N4O3S/c1-6-12(2)23-16-15(19(3,4)17(23)24)11-20-18(22-16)21-13-7-9-14(10-8-13)27(5,25)26/h7-12H,6H2,1-5H3,(H,20,21,22)/t12-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of MARK3 (unknown origin) |
Bioorg Med Chem Lett 27: 109-113 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.066
BindingDB Entry DOI: 10.7270/Q20867B1 |
More data for this
Ligand-Target Pair | |
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human)) | BDBM50208925
(CHEMBL3883548)Show InChI InChI=1S/C19H23N5O/c1-19(2)15-12-21-18(22-13-7-6-10-20-11-13)23-16(15)24(17(19)25)14-8-4-3-5-9-14/h6-7,10-12,14H,3-5,8-9H2,1-2H3,(H,21,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 346 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of MARK3 (unknown origin) |
Bioorg Med Chem Lett 27: 109-113 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.066
BindingDB Entry DOI: 10.7270/Q20867B1 |
More data for this
Ligand-Target Pair | |
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human)) | BDBM50208912
(CHEMBL3883766)Show SMILES CC[C@@H](C)N1C(=O)C(C)(C)c2cnc(Nc3cccnc3)nc12 |r| Show InChI InChI=1S/C17H21N5O/c1-5-11(2)22-14-13(17(3,4)15(22)23)10-19-16(21-14)20-12-7-6-8-18-9-12/h6-11H,5H2,1-4H3,(H,19,20,21)/t11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 738 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of MARK3 (unknown origin) |
Bioorg Med Chem Lett 27: 109-113 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.066
BindingDB Entry DOI: 10.7270/Q20867B1 |
More data for this
Ligand-Target Pair | |
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human)) | BDBM50208923
(CHEMBL3884781)Show SMILES CC(=O)N1CCC(CC1)N1C(=O)C(C)(C)c2cnc(Nc3ccccc3)nc12 Show InChI InChI=1S/C21H25N5O2/c1-14(27)25-11-9-16(10-12-25)26-18-17(21(2,3)19(26)28)13-22-20(24-18)23-15-7-5-4-6-8-15/h4-8,13,16H,9-12H2,1-3H3,(H,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of MARK3 (unknown origin) |
Bioorg Med Chem Lett 27: 109-113 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.066
BindingDB Entry DOI: 10.7270/Q20867B1 |
More data for this
Ligand-Target Pair | |
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human)) | BDBM50209094
(CHEMBL3885321)Show SMILES C[C@@H](N1C(=O)C(C)(C)c2cnc(Nc3cccnc3)nc12)c1ccc(F)cc1 |r| Show InChI InChI=1S/C21H20FN5O/c1-13(14-6-8-15(22)9-7-14)27-18-17(21(2,3)19(27)28)12-24-20(26-18)25-16-5-4-10-23-11-16/h4-13H,1-3H3,(H,24,25,26)/t13-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of MARK3 (unknown origin) |
Bioorg Med Chem Lett 27: 109-113 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.066
BindingDB Entry DOI: 10.7270/Q20867B1 |
More data for this
Ligand-Target Pair | |
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human)) | BDBM50209095
(CHEMBL3884277)Show SMILES CC(=O)N1CCC(CC1)N1C(=O)C(C)(C)c2cnc(Nc3cccnc3)nc12 Show InChI InChI=1S/C20H24N6O2/c1-13(27)25-9-6-15(7-10-25)26-17-16(20(2,3)18(26)28)12-22-19(24-17)23-14-5-4-8-21-11-14/h4-5,8,11-12,15H,6-7,9-10H2,1-3H3,(H,22,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of MARK3 (unknown origin) |
Bioorg Med Chem Lett 27: 109-113 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.066
BindingDB Entry DOI: 10.7270/Q20867B1 |
More data for this
Ligand-Target Pair | |
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human)) | BDBM50209078
(CHEMBL3884017)Show SMILES CC(=O)N1CCC(CC1)N1C(=O)C(C)(C)c2cnc(Nc3ccc(F)cc3)nc12 Show InChI InChI=1S/C21H24FN5O2/c1-13(28)26-10-8-16(9-11-26)27-18-17(21(2,3)19(27)29)12-23-20(25-18)24-15-6-4-14(22)5-7-15/h4-7,12,16H,8-11H2,1-3H3,(H,23,24,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description
Inhibition of MARK3 (unknown origin) |
Bioorg Med Chem Lett 27: 109-113 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.066
BindingDB Entry DOI: 10.7270/Q20867B1 |
More data for this
Ligand-Target Pair | |
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