Affinity Data by PubMed id=28056160

PubMed code 28056160

Found 3 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM225238 (BTK inhibitor, 3) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	30
X-Chem Pharmaceuticals					Assay Description The BTK time-resolved FRET-based competitive binding assay and cell-based BTK assays have been previously described.[Xu et al., J.Pharmacol. Exp. The...				Chembiochem 18: 864-871 (2017) Article DOI: 10.1002/cbic.201600573 BindingDB Entry DOI: 10.7270/Q22J69Q5
X-Chem Pharmaceuticals					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM225237 (BTK inhibitor, 2) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	30
X-Chem Pharmaceuticals					Assay Description The BTK time-resolved FRET-based competitive binding assay and cell-based BTK assays have been previously described.[Xu et al., J.Pharmacol. Exp. The...				Chembiochem 18: 864-871 (2017) Article DOI: 10.1002/cbic.201600573 BindingDB Entry DOI: 10.7270/Q22J69Q5
X-Chem Pharmaceuticals					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM225236 (BTK inhibitor, 1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	30
X-Chem Pharmaceuticals					Assay Description The BTK time-resolved FRET-based competitive binding assay and cell-based BTK assays have been previously described.[Xu et al., J.Pharmacol. Exp. The...				Chembiochem 18: 864-871 (2017) Article DOI: 10.1002/cbic.201600573 BindingDB Entry DOI: 10.7270/Q22J69Q5
X-Chem Pharmaceuticals					More data for this Ligand-Target Pair

* indicates data uncertainty>20%