BindingDB logo
myBDB logout

PubMed code 28689096

Compile data set for download or QSAR
Found 46 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456552
PNG
(CHEMBL4207283)
Show SMILES COc1cc(C)c(c(C)c1)-c1cccc(COc2ccc3C(CC(O)=O)CSc3c2)c1
Show InChI InChI=1S/C26H26O4S/c1-16-9-22(29-3)10-17(2)26(16)19-6-4-5-18(11-19)14-30-21-7-8-23-20(12-25(27)28)15-31-24(23)13-21/h4-11,13,20H,12,14-15H2,1-3H3,(H,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 123n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456560
PNG
(CHEMBL4217180)
Show SMILES CC(C)COc1cc(C)c(c(C)c1)-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C27H30O6S/c1-18(2)15-32-24-12-19(3)27(20(4)13-24)22-7-5-6-21(14-22)16-33-23-8-10-25(11-9-23)34(30,31)17-26(28)29/h5-14,18H,15-17H2,1-4H3,(H,28,29)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 95n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456555
PNG
(CHEMBL4213888)
Show SMILES COc1cc(C)c(c(C)c1)-c1cccc(COc2ccc(cc2)S(=O)(=O)C(C)C(O)=O)c1
Show InChI InChI=1S/C25H26O6S/c1-16-12-22(30-4)13-17(2)24(16)20-7-5-6-19(14-20)15-31-21-8-10-23(11-9-21)32(28,29)18(3)25(26)27/h5-14,18H,15H2,1-4H3,(H,26,27)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a<1.00E+3n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456558
PNG
(CHEMBL4208237)
Show SMILES Cc1cc(OCC2CC2)cc(C)c1-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C27H28O6S/c1-18-12-24(33-15-20-6-7-20)13-19(2)27(18)22-5-3-4-21(14-22)16-32-23-8-10-25(11-9-23)34(30,31)17-26(28)29/h3-5,8-14,20H,6-7,15-17H2,1-2H3,(H,28,29)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 79n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456526
PNG
(CHEMBL4209491)
Show SMILES Cc1ccc(c(Cl)c1)-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C22H19ClO5S/c1-15-5-10-20(21(23)11-15)17-4-2-3-16(12-17)13-28-18-6-8-19(9-7-18)29(26,27)14-22(24)25/h2-12H,13-14H2,1H3,(H,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 36n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456531
PNG
(CHEMBL4204628)
Show SMILES CCOc1ccc(c(Cl)c1)-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C23H21ClO6S/c1-2-29-19-8-11-21(22(24)13-19)17-5-3-4-16(12-17)14-30-18-6-9-20(10-7-18)31(27,28)15-23(25)26/h3-13H,2,14-15H2,1H3,(H,25,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 51n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456539
PNG
(CHEMBL4215289)
Show SMILES Cc1nc(sc1COc1ccc(cc1)S(=O)(=O)CC(O)=O)-c1cccc(C)c1
Show InChI InChI=1S/C20H19NO5S2/c1-13-4-3-5-15(10-13)20-21-14(2)18(27-20)11-26-16-6-8-17(9-7-16)28(24,25)12-19(22)23/h3-10H,11-12H2,1-2H3,(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 214n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456546
PNG
(CHEMBL4206179)
Show SMILES COc1ccccc1-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C22H20O6S/c1-27-21-8-3-2-7-20(21)17-6-4-5-16(13-17)14-28-18-9-11-19(12-10-18)29(25,26)15-22(23)24/h2-13H,14-15H2,1H3,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 195n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456562
PNG
(CHEMBL4211760)
Show SMILES Cc1noc(C)c1-c1cc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)ccc1Cl |(24.09,-11.88,;23.77,-10.36,;24.8,-9.21,;24.03,-7.86,;22.51,-8.19,;21.36,-7.15,;22.35,-9.73,;21,-10.5,;19.67,-9.73,;18.34,-10.5,;17,-9.73,;15.67,-10.5,;14.34,-9.73,;14.34,-8.19,;13,-7.42,;11.67,-8.19,;11.67,-9.73,;13,-10.5,;10.33,-7.41,;9.55,-6.08,;11.1,-6.07,;9,-8.18,;7.68,-7.4,;6.34,-8.16,;7.68,-5.87,;18.34,-12.04,;19.67,-12.81,;21,-12.04,;22.34,-12.81,)|
Show InChI InChI=1S/C20H18ClNO6S/c1-12-20(13(2)28-22-12)17-9-14(3-8-18(17)21)10-27-15-4-6-16(7-5-15)29(25,26)11-19(23)24/h3-9H,10-11H2,1-2H3,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 214n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456570
PNG
(CHEMBL4218236)
Show SMILES Cc1ccc(C)n1-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C21H21NO5S/c1-15-6-7-16(2)22(15)18-5-3-4-17(12-18)13-27-19-8-10-20(11-9-19)28(25,26)14-21(23)24/h3-12H,13-14H2,1-2H3,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 129n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456527
PNG
(CHEMBL4207821)
Show SMILES COc1cc(C)c(c(C)c1)-c1cccc(COc2ccc3C(CC(O)=O)CS(=O)(=O)c3c2)c1
Show InChI InChI=1S/C26H26O6S/c1-16-9-22(31-3)10-17(2)26(16)19-6-4-5-18(11-19)14-32-21-7-8-23-20(12-25(27)28)15-33(29,30)24(23)13-21/h4-11,13,20H,12,14-15H2,1-3H3,(H,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a<1.00E+3n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456528
PNG
(CHEMBL4211807)
Show SMILES Cc1noc(C)c1-c1ccc(C)c(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C21H21NO6S/c1-13-4-5-16(21-14(2)22-28-15(21)3)10-17(13)11-27-18-6-8-19(9-7-18)29(25,26)12-20(23)24/h4-10H,11-12H2,1-3H3,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 427n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456532
PNG
(CHEMBL4214530)
Show SMILES CC(C)c1ccccc1-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C24H24O5S/c1-17(2)22-8-3-4-9-23(22)19-7-5-6-18(14-19)15-29-20-10-12-21(13-11-20)30(27,28)16-24(25)26/h3-14,17H,15-16H2,1-2H3,(H,25,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 74n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456543
PNG
(CHEMBL4213359)
Show SMILES COc1cc(C)c(c(C)c1)-c1cccc(COc2ccc(cc2)S(=O)(=O)C2(CC2)C(O)=O)c1
Show InChI InChI=1S/C26H26O6S/c1-17-13-22(31-3)14-18(2)24(17)20-6-4-5-19(15-20)16-32-21-7-9-23(10-8-21)33(29,30)26(11-12-26)25(27)28/h4-10,13-15H,11-12,16H2,1-3H3,(H,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a<1.00E+3n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456568
PNG
(CHEMBL4206505)
Show SMILES Cc1noc(C)c1-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C20H19NO6S/c1-13-20(14(2)27-21-13)16-5-3-4-15(10-16)11-26-17-6-8-18(9-7-17)28(24,25)12-19(22)23/h3-10H,11-12H2,1-2H3,(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 269n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456536
PNG
(CHEMBL4206875)
Show SMILES Cc1noc(C)c1-c1ccc(Cl)c(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C20H18ClNO6S/c1-12-20(13(2)28-22-12)14-3-8-18(21)15(9-14)10-27-16-4-6-17(7-5-16)29(25,26)11-19(23)24/h3-9H,10-11H2,1-2H3,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 234n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456540
PNG
(CHEMBL4205537)
Show SMILES Cc1nc(sc1COc1ccc(cc1)S(=O)(=O)CC(O)=O)-c1ccccc1F
Show InChI InChI=1S/C19H16FNO5S2/c1-12-17(27-19(21-12)15-4-2-3-5-16(15)20)10-26-13-6-8-14(9-7-13)28(24,25)11-18(22)23/h2-9H,10-11H2,1H3,(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 550n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456542
PNG
(CHEMBL4217768)
Show SMILES Cc1ccccc1-c1ccc(COc2cccc(c2)S(=O)(=O)CC(O)=O)cc1
Show InChI InChI=1S/C22H20O5S/c1-16-5-2-3-8-21(16)18-11-9-17(10-12-18)14-27-19-6-4-7-20(13-19)28(25,26)15-22(23)24/h2-13H,14-15H2,1H3,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a<1.00E+3n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456548
PNG
(CHEMBL4210139)
Show SMILES Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C27H30O8S2/c1-19-14-24(34-12-5-13-36(3,30)31)15-20(2)27(19)22-7-4-6-21(16-22)17-35-23-8-10-25(11-9-23)37(32,33)18-26(28)29/h4,6-11,14-16H,5,12-13,17-18H2,1-3H3,(H,28,29)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 170n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456564
PNG
(CHEMBL4218291)
Show SMILES COc1cc(C)c(c(C)c1)-c1cccc(COc2ccc(cc2)S(=O)(=O)C(C)(C)C(O)=O)c1
Show InChI InChI=1S/C26H28O6S/c1-17-13-22(31-5)14-18(2)24(17)20-8-6-7-19(15-20)16-32-21-9-11-23(12-10-21)33(29,30)26(3,4)25(27)28/h6-15H,16H2,1-5H3,(H,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a<1.00E+3n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456567
PNG
(CHEMBL4202452)
Show SMILES Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(COc2ccc(CCC(O)=O)cc2)c1
Show InChI InChI=1S/C28H32O6S/c1-20-16-26(33-14-5-15-35(3,31)32)17-21(2)28(20)24-7-4-6-23(18-24)19-34-25-11-8-22(9-12-25)10-13-27(29)30/h4,6-9,11-12,16-18H,5,10,13-15,19H2,1-3H3,(H,29,30)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 15n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456569
PNG
(CHEMBL4210719)
Show SMILES CCCOc1cc(C)c(c(C)c1)-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C26H28O6S/c1-4-12-31-23-13-18(2)26(19(3)14-23)21-7-5-6-20(15-21)16-32-22-8-10-24(11-9-22)33(29,30)17-25(27)28/h5-11,13-15H,4,12,16-17H2,1-3H3,(H,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 69n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456571
PNG
(CHEMBL4214028)
Show SMILES OC(=O)CS(=O)(=O)c1ccc(OCc2cccc(c2)-c2ccccc2F)cc1
Show InChI InChI=1S/C21H17FO5S/c22-20-7-2-1-6-19(20)16-5-3-4-15(12-16)13-27-17-8-10-18(11-9-17)28(25,26)14-21(23)24/h1-12H,13-14H2,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 257n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456529
PNG
(CHEMBL4218763)
Show SMILES OC(=O)CS(=O)(=O)c1ccc(OCc2cccc(Oc3ccccc3)c2)cc1
Show InChI InChI=1S/C21H18O6S/c22-21(23)15-28(24,25)20-11-9-17(10-12-20)26-14-16-5-4-8-19(13-16)27-18-6-2-1-3-7-18/h1-13H,14-15H2,(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 98n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456547
PNG
(CHEMBL4205774)
Show SMILES OC(=O)CS(=O)(=O)c1ccc(OCc2cccc(c2)-c2ccccc2)cc1
Show InChI InChI=1S/C21H18O5S/c22-21(23)15-27(24,25)20-11-9-19(10-12-20)26-14-16-5-4-8-18(13-16)17-6-2-1-3-7-17/h1-13H,14-15H2,(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 288n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456553
PNG
(CHEMBL4212170)
Show SMILES COc1cc(C)c(c(C)c1)-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C24H24O6S/c1-16-11-21(29-3)12-17(2)24(16)19-6-4-5-18(13-19)14-30-20-7-9-22(10-8-20)31(27,28)15-23(25)26/h4-13H,14-15H2,1-3H3,(H,25,26)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 58n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456530
PNG
(CHEMBL4210871)
Show SMILES Cc1nc(sc1COc1ccc(cc1)S(=O)(=O)CC(O)=O)-c1ccc(F)cc1
Show InChI InChI=1S/C19H16FNO5S2/c1-12-17(27-19(21-12)13-2-4-14(20)5-3-13)10-26-15-6-8-16(9-7-15)28(24,25)11-18(22)23/h2-9H,10-11H2,1H3,(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 191n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456534
PNG
(CHEMBL4202936)
Show SMILES COc1cc(C)c(c(C)c1)-c1cccc(COc2ccc3C(CC(O)=O)CC(=O)c3c2)c1
Show InChI InChI=1S/C27H26O5/c1-16-9-22(31-3)10-17(2)27(16)19-6-4-5-18(11-19)15-32-21-7-8-23-20(13-26(29)30)12-25(28)24(23)14-21/h4-11,14,20H,12-13,15H2,1-3H3,(H,29,30)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 234n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456537
PNG
(CHEMBL4206915)
Show SMILES Cc1noc(C)c1-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1C |(24.09,-11.88,;23.77,-10.36,;24.8,-9.21,;24.03,-7.86,;22.51,-8.19,;21.36,-7.15,;22.35,-9.73,;21,-10.5,;21,-12.04,;19.67,-12.81,;18.34,-12.04,;18.34,-10.5,;17,-9.73,;15.67,-10.5,;14.34,-9.73,;14.34,-8.19,;13,-7.42,;11.67,-8.19,;11.67,-9.73,;13,-10.5,;10.33,-7.41,;9.55,-6.08,;11.1,-6.07,;9,-8.18,;7.68,-7.4,;6.34,-8.16,;7.68,-5.87,;19.67,-9.73,;19.67,-8.19,)|
Show InChI InChI=1S/C21H21NO6S/c1-13-16(5-4-6-19(13)21-14(2)22-28-15(21)3)11-27-17-7-9-18(10-8-17)29(25,26)12-20(23)24/h4-10H,11-12H2,1-3H3,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 363n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456538
PNG
(CHEMBL4213829)
Show SMILES CO\N=C(/COc1ccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)cc1)c1ccccc1
Show InChI InChI=1S/C24H23NO7S/c1-30-25-23(19-5-3-2-4-6-19)16-32-20-9-7-18(8-10-20)15-31-21-11-13-22(14-12-21)33(28,29)17-24(26)27/h2-14H,15-17H2,1H3,(H,26,27)/b25-23+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 178n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456544
PNG
(CHEMBL4208972)
Show SMILES CCC(C(O)=O)S(=O)(=O)c1ccc(OCc2cccc(c2)-c2c(C)cc(OC)cc2C)cc1
Show InChI InChI=1S/C26H28O6S/c1-5-24(26(27)28)33(29,30)23-11-9-21(10-12-23)32-16-19-7-6-8-20(15-19)25-17(2)13-22(31-4)14-18(25)3/h6-15,24H,5,16H2,1-4H3,(H,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a<1.00E+3n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456551
PNG
(CHEMBL4203471)
Show SMILES COc1cc(C)c(c(C)c1)-c1cccc(COc2ccc3C(CC(O)=O)CC(O)c3c2)c1
Show InChI InChI=1S/C27H28O5/c1-16-9-22(31-3)10-17(2)27(16)19-6-4-5-18(11-19)15-32-21-7-8-23-20(13-26(29)30)12-25(28)24(23)14-21/h4-11,14,20,25,28H,12-13,15H2,1-3H3,(H,29,30)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 550n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456557
PNG
(CHEMBL4209845)
Show SMILES Cc1cccc(C)c1-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C23H22O5S/c1-16-5-3-6-17(2)23(16)19-8-4-7-18(13-19)14-28-20-9-11-21(12-10-20)29(26,27)15-22(24)25/h3-13H,14-15H2,1-2H3,(H,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 66n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456559
PNG
(CHEMBL4206053)
Show SMILES OC(=O)CS(=O)(=O)c1cccc(OCc2ccc(cc2)-c2ccccc2)c1
Show InChI InChI=1S/C21H18O5S/c22-21(23)15-27(24,25)20-8-4-7-19(13-20)26-14-16-9-11-18(12-10-16)17-5-2-1-3-6-17/h1-13H,14-15H2,(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a<1.00E+3n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456561
PNG
(CHEMBL4166922)
Show SMILES Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(COc2ccc3[C@@H](COc3c2)C(O)=O)c1 |r|
Show InChI InChI=1S/C28H30O7S/c1-18-12-23(33-10-5-11-36(3,31)32)13-19(2)27(18)21-7-4-6-20(14-21)16-34-22-8-9-24-25(28(29)30)17-35-26(24)15-22/h4,6-9,12-15,25H,5,10-11,16-17H2,1-3H3,(H,29,30)/t25-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 42n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456565
PNG
(CHEMBL4209622)
Show SMILES OC(=O)CS(=O)(=O)c1ccc(OCc2cccc(c2)-c2ccccc2C(F)(F)F)cc1
Show InChI InChI=1S/C22H17F3O5S/c23-22(24,25)20-7-2-1-6-19(20)16-5-3-4-15(12-16)13-30-17-8-10-18(11-9-17)31(28,29)14-21(26)27/h1-12H,13-14H2,(H,26,27)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 52n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456566
PNG
(CHEMBL4215675)
Show SMILES CCOc1cc(C)c(c(C)c1)-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C25H26O6S/c1-4-30-22-12-17(2)25(18(3)13-22)20-7-5-6-19(14-20)15-31-21-8-10-23(11-9-21)32(28,29)16-24(26)27/h5-14H,4,15-16H2,1-3H3,(H,26,27)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 63n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456535
PNG
(CHEMBL4214140)
Show SMILES Cc1cccc(C)c1-c1cccc(COc2ccc(SCC(O)=O)cc2)c1
Show InChI InChI=1S/C23H22O3S/c1-16-5-3-6-17(2)23(16)19-8-4-7-18(13-19)14-26-20-9-11-21(12-10-20)27-15-22(24)25/h3-13H,14-15H2,1-2H3,(H,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 195n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456545
PNG
(CHEMBL4211064)
Show SMILES OC(=O)CS(=O)(=O)c1ccc(OCc2cccc(c2)-c2ccccc2C#N)cc1
Show InChI InChI=1S/C22H17NO5S/c23-13-18-5-1-2-7-21(18)17-6-3-4-16(12-17)14-28-19-8-10-20(11-9-19)29(26,27)15-22(24)25/h1-12H,14-15H2,(H,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 457n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456549
PNG
(CHEMBL4205241)
Show SMILES COCCOc1cc(C)c(c(C)c1)-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C26H28O7S/c1-18-13-23(32-12-11-31-3)14-19(2)26(18)21-6-4-5-20(15-21)16-33-22-7-9-24(10-8-22)34(29,30)17-25(27)28/h4-10,13-15H,11-12,16-17H2,1-3H3,(H,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 126n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456563
PNG
(CHEMBL4210351)
Show SMILES Cc1nc(sc1COc1ccc(cc1)S(=O)(=O)CC(O)=O)-c1cccc(Cl)c1
Show InChI InChI=1S/C19H16ClNO5S2/c1-12-17(27-19(21-12)13-3-2-4-14(20)9-13)10-26-15-5-7-16(8-6-15)28(24,25)11-18(22)23/h2-9H,10-11H2,1H3,(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 251n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456533
PNG
(CHEMBL4217477)
Show SMILES Cc1ccccc1-c1cccc(COc2ccc(cc2)S(=O)(=O)CC(O)=O)c1
Show InChI InChI=1S/C22H20O5S/c1-16-5-2-3-8-21(16)18-7-4-6-17(13-18)14-27-19-9-11-20(12-10-19)28(25,26)15-22(23)24/h2-13H,14-15H2,1H3,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 47n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456541
PNG
(CHEMBL4210415)
Show SMILES Cc1nc(sc1COc1ccc(cc1)S(=O)(=O)CC(O)=O)-c1ccccc1
Show InChI InChI=1S/C19H17NO5S2/c1-13-17(26-19(20-13)14-5-3-2-4-6-14)11-25-15-7-9-16(10-8-15)27(23,24)12-18(21)22/h2-10H,11-12H2,1H3,(H,21,22)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 331n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456550
PNG
(CHEMBL4215143)
Show SMILES CO\N=C1/CC(CC(O)=O)c2ccc(OCc3cccc(c3)-c3c(C)cc(OC)cc3C)cc12
Show InChI InChI=1S/C28H29NO5/c1-17-10-23(32-3)11-18(2)28(17)20-7-5-6-19(12-20)16-34-22-8-9-24-21(14-27(30)31)13-26(29-33-4)25(24)15-22/h5-12,15,21H,13-14,16H2,1-4H3,(H,30,31)/b29-26+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a<1.00E+3n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456556
PNG
(CHEMBL4218946)
Show SMILES OC(=O)CS(=O)(=O)c1ccc(OCc2cccc(c2)-c2ccccc2Cl)cc1
Show InChI InChI=1S/C21H17ClO5S/c22-20-7-2-1-6-19(20)16-5-3-4-15(12-16)13-27-17-8-10-18(11-9-17)28(25,26)14-21(23)24/h1-12H,13-14H2,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 29n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
Free fatty acid receptor 1


(Homo sapiens (Human))		BDBM50456554
PNG
(CHEMBL4205991)
Show SMILES Cc1nc(sc1COc1ccc(cc1)S(=O)(=O)CC(O)=O)-c1cccc(F)c1
Show InChI InChI=1S/C19H16FNO5S2/c1-12-17(27-19(21-12)13-3-2-4-14(20)9-13)10-26-15-5-7-16(8-6-15)28(24,25)11-18(22)23/h2-9H,10-11H2,1H3,(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 275n/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human FFA1 receptor expressed in CHO cells assessed as increase in intracellular calcium flux by Fluo 4AM dye-based FLIPR assay

Eur J Med Chem 138: 458-479 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.001
BindingDB Entry DOI: 10.7270/Q269765Z
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%